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CPEB3 Gene

protein-coding   GIFtS: 52
GCID: GC10M093798

Cytoplasmic Polyadenylation Element Binding Protein 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cytoplasmic Polyadenylation Element Binding Protein 31 2
CPE-BP32 3
CPE-Binding Protein 32 3
hCPEB-32 3
KIAA09403 5
Cytoplasmic Polyadenylation Element-Binding Protein 32

External Ids:    HGNC: 217461   Entrez Gene: 228492   Ensembl: ENSG000001078647   OMIM: 6106065   UniProtKB: Q8NE353   

Export aliases for CPEB3 gene to outside databases

Previous GC identifers: GC10M093939 GC10M093472 GC10M093473 GC10M087437


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CPEB3 Gene:
CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a protein-coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is CPEB2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CPEB3 gene promoter:
         Pax-5   Nkx2-2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   CUTL1   LCR-F1   HEN1   COMP1   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCPEB3 promoter sequence
   Search Chromatin IP Primers for CPEB3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CPEB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23.32   Ensembl cytogenetic band:  10q23.32   HGNC cytogenetic band: 10q23.33

CPEB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPEB3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M093798:  view genomic region     (about GC identifiers)

Start:
93,806,449 bp from pter      End:
94,050,875 bp from pter
Size:
244,427 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CPEB3_HUMAN, Q8NE35 (See protein sequence)
Recommended Name: Cytoplasmic polyadenylation element-binding protein 3  
Size: 698 amino acids; 76014 Da
Sequence caution: Sequence=BAA76784.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CPEB3:
2DNL (3D)    
Secondary accessions: Q5T389 Q9NQJ7 Q9Y2E9
Alternative splicing: 2 isoforms:  Q8NE35-1   Q8NE35-2   

Explore the universe of human proteins at neXtProt for CPEB3: NX_Q8NE35

Explore proteomics data for CPEB3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CPEB3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001171608.1  NP_055727.3  

    ENSEMBL proteins: 
     ENSP00000398310   ENSP00000265997  

    CPEB3 Human Recombinant Protein Products:

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    Novus Biologicals CPEB3 Protein
    Novus Biologicals CPEB3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CPEB3

     
    Search eBioscience for Proteins for CPEB3 

     
    antibodies-online proteins for CPEB3 (3 products) 

     
    antibodies-online peptides for CPEB3

    CPEB3 Antibody Products:

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    Search for Antibodies for CPEB3 at Abcam
    Cloud-Clone Corp. Antibodies for CPEB3
    Search ThermoFisher Antibodies for CPEB3
    antibodies-online antibodies for CPEB3 (27 products) 

    CPEB3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for CPEB3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CPEB3
    Cloud-Clone Corp. CLIAs for CPEB3
    Search eBioscience for ELISAs for CPEB3 
    antibodies-online kits for CPEB3 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q8NE35

    ProtoNet protein and cluster: Q8NE35

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: CPEB3_HUMAN, Q8NE35
    Similarity: Belongs to the RRM CPEB family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    Find genes that share domains with CPEB3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): Selected molecular function terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0000900translation repressor activity, nucleic acid binding ISS--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IDA--
    GO:0003730mRNA 3'-UTR binding ISS--
         
    Find genes that share ontologies with CPEB3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CPEB3:
     Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CPEB3

    miRNA
    Products:
        
    miRTarBase miRNAs that target CPEB3:
    hsa-mir-196a-5p (MIRT026085), hsa-mir-29a-3p (MIRT005591), hsa-mir-320a (MIRT044792), hsa-mir-26a-5p (MIRT005588), hsa-mir-23b-3p (MIRT023472), hsa-mir-21-5p (MIRT030711)

    Block miRNA regulation of human, mouse, rat CPEB3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CPEB3 (see all 202):
    hsa-miR-1914* hsa-miR-106a hsa-miR-4305 hsa-miR-128 hsa-miR-519a hsa-miR-1243 hsa-miR-508-5p hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat CPEB3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): CPEB3 (NM_014912)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPEB3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPEB3

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    Browse ESI BIO Cell Lines and PureStem Progenitors for CPEB3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm ISS--
    GO:0030014CCR4-NOT complex IDA--
    GO:0030425dendrite ISS--
    GO:0043005neuron projection ISS--

    Find genes that share ontologies with CPEB3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CPEB3
    Interactions:

        Search GeneGlobe Interaction Network for CPEB3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for CPEB3 (Q8NE351, 2, 3 ENSP000002659974) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TOB1P506161, 2, 3, ENSP000002689574EBI-8596191,EBI-723281 MINT-8176462 MINT-8176507 MINT-8176406 MINT-8176523 MINT-8173967 MINT-8176376 MINT-8176426 MINT-8176476 I2D: score=1 STRING: ENSP00000268957
    CNOT7Q9UIV12, ENSP000003552794MINT-8173967 MINT-8176376 MINT-8176406 STRING: ENSP00000355279
    TOB2Q141062, 3, ENSP000003313054MINT-8176448 I2D: score=1 STRING: ENSP00000331305
    NEURL1O760503, ENSP000003587954I2D: score=1 STRING: ENSP00000358795
    KXD1ENSP000002223074STRING: ENSP00000222307
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA--
    GO:0006412translation ISS--
    GO:0007616long-term memory ISS--
    GO:0017148negative regulation of translation IDA--
    GO:0045727positive regulation of translation ISS--

    Find genes that share ontologies with CPEB3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CPEB3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CPEB3 gene (2 alternative transcripts): 
    NM_001178137.1  NM_014912.4  

    Unigene Cluster for CPEB3:

    Cytoplasmic polyadenylation element binding protein 3
    Hs.131683  [show with all ESTs]
    Unigene Representative Sequence: NM_014912
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000412050(uc001khv.2) ENST00000265997
    miRNA
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    Block miRNA regulation of human, mouse, rat CPEB3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CPEB3 (see all 202):
    hsa-miR-1914* hsa-miR-106a hsa-miR-4305 hsa-miR-128 hsa-miR-519a hsa-miR-1243 hsa-miR-508-5p hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CPEB3
    Predesigned siRNA for gene silencing in human, mouse, rat CPEB3
    Clone
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    OriGene clones in human, mouse for CPEB3 (see all 10)
    OriGene ORF clones in mouse, rat for CPEB3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CPEB3 (NM_014912)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CPEB3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPEB3
    Primer
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    OriGene qPCR primer pairs and template standards for CPEB3
    OriGene qSTAR qPCR primer pairs in human, mouse for CPEB3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CPEB3
      QuantiTect SYBR Green Assays in human, mouse, rat CPEB3
      QuantiFast Probe-based Assays in human, mouse, rat CPEB3

    Additional mRNA sequence: 

    AB023157.1 AK127060.1 AK302576.1 BC036444.2 

    7 DOTS entries:

    DT.452787  DT.402838  DT.100022631  DT.65285379  DT.92420332  DT.121222591  DT.75127040 

    Selected AceView cDNA sequences (see all 57):

    BF509277 AB023157 BE673893 NM_014912 CK821783 BU159553 BX109142 CB159683 
    CK821782 CD104192 BU948688 AI637670 BV196267 CA848776 AI827590 AK127060 
    BC036444 H66447 BX486614 AI016770 BM311440 AW130642 AL600688 AA904806 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CPEB3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTAAAATA
    CPEB3 Expression
    About this image


    CPEB3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    CPEB3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CPEB3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.131683
        Custom PCR Arrays for CPEB3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CPEB3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cpeb31 , 5 cytoplasmic polyadenylation element binding protein more1, 5 90.84(n)1
    96.12(a)1
      19 (32.08 cM)5
    2089221  NM_198300.21  NP_938042.21 
     370212915 
    chicken
    (Gallus gallus)
    Aves CPEB31 cytoplasmic polyadenylation element binding protein more 83.16(n)
    90.47(a)
      423816  XM_004942160.1  XP_004942217.1 
    lizard
    (Anolis carolinensis)
    Reptilia CPEB36
    cytoplasmic polyadenylation element binding protei...
    88(a)
    1 ↔ 1
    GL343262.1(1707911-1802855)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cpeb31 cytoplasmic polyadenylation element binding protein more 78.27(n)
    85.39(a)
      548679  NM_001015925.2  NP_001015925.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cpeb31 cytoplasmic polyadenylation element binding protein more 74.03(n)
    79.68(a)
      100005268  NM_001167662.1  NP_001161134.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta orb26
    --
    44(a)
    1 → many
    3L(8930200-8947563)
    worm
    (Caenorhabditis elegans)
    Secernentea cpb-16
    cpb-26
    (see all 3)
    Protein CPB-2 (cpb-2) mRNA, complete cds
    (see all 3)
    33(a)
    29(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    III(9322316-9324733) WBGene00000770
    II(6192833-6195204) WBGene00000771


    ENSEMBL Gene Tree for CPEB3 (if available)
    TreeFam Gene Tree for CPEB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CPEB3 gene
    CPEB22  CPEB42  ENSG000002608362  CPEB12  
    5 SIMAP similar genes for CPEB3 using alignment to 3 protein entries:     CPEB3_HUMAN (see all proteins):
    DKFZp686L03182    CPEB 4 variant    CPEB2    CPEB4    CPEB1

    Find genes that share paralogs with CPEB3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CPEB3 (see all 3891)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1483276051,2
    Cuntested193985714(+) CCGGGA/C/TGTGGT 2 -- int10--------
    rs1877457721,2
    --93807907(+) TGACAC/TCCGAG 2 -- int10--------
    rs1506194431,2
    --93808024(+) TTCCTC/GTATGA 2 -- int10--------
    rs1396846271,2
    --93808033(+) GACTCC/TGATAT 2 -- int10--------
    rs1439480741,2
    --93808068(+) ATTCGG/TCCTGG 2 -- int10--------
    rs1435466051,2
    C--93808116(+) GGCAG-/TTTTTCT 2 -- int10--------
    rs111868101,2
    C,F,A,H--93808119(+) AGTTTT/CTCTCT 2 -- int116Minor allele frequency- C:0.33NS EA WA NA CSA 1982
    rs618751821,2
    C--93808142(+) CTCTCA/TCTCAC 2 -- int11Minor allele frequency- T:0.00NA 2
    rs2009366661,2
    C--93808143(+) CTCTC-/ACACA 
    C
    /CACACA
    TCACA
    4 -- cds10--------
    rs111868111,2
    C,A--93808144(+) CTCTCA/TCACAC 2 -- int13Minor allele frequency- T:0.00NA CSA 5

    HapMap Linkage Disequilibrium report for CPEB3 (93806449 - 94050875 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CPEB3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2671036CNV Deletion23128226
    esv2664459CNV Deletion23128226
    esv2739562CNV Deletion23290073
    nsv895893CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CPEB3
    DNA2.0 Custom Variant and Variant Library Synthesis for CPEB3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610606    OMIM disorders: --


    Find genes that share disorders with CPEB3           About GenesLikeMe

    Genetic Association Database (GAD): CPEB3
    Human Genome Epidemiology (HuGE) Navigator: CPEB3 (3 documents)

    Export disorders for CPEB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CPEB3 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with CPEB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. CPEB3 is associated with human episodic memory. (PubMed id 19503753)1, 4 Vogler C....de Quervain D.J. (Front Behav Neurosci 2009)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    7. CPEB2, a novel putative translational regulator in mouse haploid germ cells. (PubMed id 12672660)1, 3 Kurihara Y....Uesugi S. (Biol. Reprod. 2003)
    8. Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons. (PubMed id 22711986)1 Wang C.F. and Huang Y.S. (Mol. Cell. Biol. 2012)
    9. Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase. (PubMed id 21336257)1 Hosoda N....Hoshino S. (EMBO J. 2011)
    10. The human HDV-like CPEB3 ribozyme is intrinsically fast-reacting. (PubMed id 20524672)1 Chadalavada D.M....Bevilacqua P.C. (Biochemistry 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22849 HGNC: 21746 AceView: CPEB3 Ensembl:ENSG00000107864 euGenes: HUgn22849
    ECgene: CPEB3 H-InvDB: CPEB3

    (According to HUGE)
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    HUGE: KIAA0940

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CPEB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for CPEB3 gene:
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