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CPEB2 Gene

protein-coding   GIFtS: 50
GCID: GC04P015005

Cytoplasmic Polyadenylation Element Binding Protein 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cytoplasmic Polyadenylation Element Binding Protein 21 2
CPE-BP22 3
CPE-Binding Protein 22 3
hCPEB-22 3
CPEB-22
Cytoplasmic Polyadenylation Element-Binding Protein 22

External Ids:    HGNC: 217451   Entrez Gene: 1328642   Ensembl: ENSG000001374497   OMIM: 6106055   UniProtKB: Q7Z5Q13   

Export aliases for CPEB2 gene to outside databases

Previous GC identifers: GC04P014707 GC04P014756 GC04P014681 GC04P014355


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CPEB2 Gene:
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB),
an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and
spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in
transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct
isoforms have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for CPEB2 Gene:
CPEB2 (cytoplasmic polyadenylation element binding protein 2) is a protein-coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is CPEB4.

UniProtKB/Swiss-Prot: CPEB2_HUMAN, Q7Z5Q1
Function: May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid
spermatids. Binds to poly(U) RNA oligomers (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_006316.17  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CPEB2 gene promoter:
         AhR   SRY   S8   POU2F1   HOXA3   POU2F1a   HSF2   NF-kappaB1   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCPEB2 promoter sequence
   Search Chromatin IP Primers for CPEB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CPEB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.33   Ensembl cytogenetic band:  4p15.33   HGNC cytogenetic band: 4p15.33

CPEB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPEB2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P015005:  view genomic region     (about GC identifiers)

Start:
15,004,298 bp from pter      End:
15,071,777 bp from pter
Size:
67,480 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CPEB2_HUMAN, Q7Z5Q1 (See protein sequence)
Recommended Name: Cytoplasmic polyadenylation element-binding protein 2  
Size: 589 amino acids; 64944 Da
Subunit: Interacts with PAPD4/GLD2 (By similarity)
Secondary accessions: Q3B8N6 Q3MI89 Q3MI90 Q3MI92 Q7Z5Q0
Alternative splicing: 6 isoforms:  Q7Z5Q1-2   Q7Z5Q1-3   Q7Z5Q1-4   Q7Z5Q1-5   Q7Z5Q1-6   Q7Z5Q1-7   

Explore the universe of human proteins at neXtProt for CPEB2: NX_Q7Z5Q1

Explore proteomics data for CPEB2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CPEB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001170852.1  NP_001170853.1  NP_001170854.1  NP_001170855.1  NP_872291.2  NP_872587.2  

    ENSEMBL proteins: 
     ENSP00000424084   ENSP00000334058   ENSP00000259997   ENSP00000371832   ENSP00000371838  
     ENSP00000423890   ENSP00000443985   ENSP00000437884   ENSP00000414270  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z5Q1

    ProtoNet protein and cluster: Q7Z5Q1

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: CPEB2_HUMAN, Q7Z5Q1
    Similarity: Belongs to the RRM CPEB family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    Find genes that share domains with CPEB2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CPEB2_HUMAN, Q7Z5Q1
    Function: May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid
    spermatids. Binds to poly(U) RNA oligomers (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0000900translation repressor activity, nucleic acid binding ISS--
    GO:0003676nucleic acid binding ----
    GO:0005095GTPase inhibitor activity ISS--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CPEB2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CPEB2

    miRNA
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    miRTarBase miRNAs that target CPEB2:
    hsa-mir-335-5p (MIRT017639), hsa-mir-210-3p (MIRT003167), hsa-mir-26a-5p (MIRT005587), hsa-mir-103a-3p (MIRT027130), hsa-mir-92a-3p (MIRT005590)

    Block miRNA regulation of human, mouse, rat CPEB2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CPEB2 (see all 243):
    hsa-miR-134 hsa-miR-519a hsa-miR-502-3p hsa-miR-1273d hsa-miR-298 hsa-miR-92b hsa-miR-130b hsa-miR-520b
    SwitchGear 3'UTR luciferase reporter plasmidCPEB2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CPEB2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CPEB2_HUMAN, Q7Z5Q1: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005844polysome ----
    GO:1990124messenger ribonucleoprotein complex ISS--

    Find genes that share ontologies with CPEB2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CPEB2
    Interactions:

        Search GeneGlobe Interaction Network for CPEB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for CPEB2 (ENSP000002599974) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BICC1ENSP000003629934STRING: ENSP00000362993
    ANKS6ENSP000002978374STRING: ENSP00000297837
    PAPOLBENSP000003847004STRING: ENSP00000384700
    HDLBPENSP000003120424STRING: ENSP00000312042
    PUM1ENSP000003917234STRING: ENSP00000391723
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    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032869cellular response to insulin stimulus IDA18752464
    GO:0033125negative regulation of GTP catabolic process ----
    GO:0034260negative regulation of GTPase activity ISS--
    GO:0034599cellular response to oxidative stress ISS--
    GO:0045900negative regulation of translational elongation ----

    Find genes that share ontologies with CPEB2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CPEB2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CPEB2 gene (6 alternative transcripts): 
    NM_001177381.1  NM_001177382.1  NM_001177383.1  NM_001177384.1  NM_182485.2  NM_182646.2  

    Unigene Cluster for CPEB2:

    Cytoplasmic polyadenylation element binding protein 2
    Hs.656937  [show with all ESTs]
    Unigene Representative Sequence: NM_001177382
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507071 ENST00000345451 ENST00000259997 ENST00000382395 ENST00000382401
    ENST00000503926 ENST00000509684 ENST00000538197(uc003gnk.2) ENST00000541112(uc003gni.2)
    ENST00000442003(uc003gnl.2 uc003gnm.2 uc003gnn.2 uc003gnj.2)

    miRNA
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    Block miRNA regulation of human, mouse, rat CPEB2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CPEB2 (see all 243):
    hsa-miR-134 hsa-miR-519a hsa-miR-502-3p hsa-miR-1273d hsa-miR-298 hsa-miR-92b hsa-miR-130b hsa-miR-520b
    SwitchGear 3'UTR luciferase reporter plasmidCPEB2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CPEB2
    Predesigned siRNA for gene silencing in human, mouse, rat CPEB2
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    GenScript: all cDNA clones in your preferred vector (see all 6): CPEB2 (NM_182485)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPEB2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CPEB2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CPEB2
      QuantiTect SYBR Green Assays in human, mouse, rat CPEB2
      QuantiFast Probe-based Assays in human, mouse, rat CPEB2

    Additional mRNA sequence: 

    AK094566.1 AY247744.1 AY255519.1 BC103939.1 BC103940.1 BC103941.1 BC103942.1 BC105925.1 
    BX640753.1 

    6 DOTS entries:

    DT.101982326  DT.410224  DT.418806  DT.95206866  DT.121248966  DT.40262257 

    Selected AceView cDNA sequences (see all 76):

    BQ000575 CA395047 AA377165 AW299792 AY255519 AI589089 AA613805 CA394718 
    CB528992 AY247744 NM_182646 AK094566 AW964015 NM_182485 BU686906 AI659732 
    AA429688 BQ638087 AI701687 AL700535 BU854218 BG748532 BG388881 BM706423 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CPEB2 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b
    SP1:                    -                                                           -               
    SP2:                    -     -                                                     -               
    SP3:                    -                       -                                   -               
    SP4:                          -                                                     -               
    SP5:                    -     -                 -                                   -               


    ECgene alternative splicing isoforms for CPEB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CPEB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTATGGA
    CPEB2 Expression
    About this image


    CPEB2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Renal Collecting Duct System
     
     Neurons
             Glycinergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Glycinergic Amacrine Cells Inner Nuclear Layer
     
     Epidermis (Integumentary System)
    CPEB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CPEB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656937
        Custom PCR Arrays for CPEB2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CPEB2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cpeb21 , 5 cytoplasmic polyadenylation element binding protein more1, 5 88.09(n)1
    88.61(a)1
      5 (23.65 cM)5
    2312071  NM_175937.31  NP_787951.21 
     432339565 
    chicken
    (Gallus gallus)
    Aves CPEB21 cytoplasmic polyadenylation element binding protein more 90.04(n)
    99.29(a)
      422832  XM_420779.4  XP_420779.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    97(a)
    84(a)
    1 ↔ many
    1 ↔ many
    GL343513.1(232793-247403)
    GL343513.1(289626-318387)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.70842 Xenopus laevis transcribed sequence with moderate similarity more 84.16(n)    BX849528.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cpeb21 cytoplasmic polyadenylation element binding protein more 70.51(n)
    78.54(a)
      100330483  XM_002666399.3  XP_002666445.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta orb26
    --
    44(a)
    1 → many
    3L(8930200-8947563)
    worm
    (Caenorhabditis elegans)
    Secernentea cpb-16
    cpb-26
    (see all 3)
    Protein CPB-2 (cpb-2) mRNA, complete cds
    (see all 3)
    31(a)
    28(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    III(9322316-9324733) WBGene00000770
    II(6192833-6195204) WBGene00000771


    ENSEMBL Gene Tree for CPEB2 (if available)
    TreeFam Gene Tree for CPEB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CPEB2 gene
    CPEB42  ENSG000002608362  CPEB32  CPEB12  
    5 SIMAP similar genes for CPEB2 using alignment to 6 protein entries:     CPEB2_HUMAN (see all proteins):
    DKFZp686L03182    CPEB 4 variant    CPEB4    CPEB3    CPEB1

    Find genes that share paralogs with CPEB2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CPEB2 (see all 1211)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1912408691,2
    --15005838(+) CCCGCC/TGCCCG 12 P L mis10--------
    rs1120054611,2
    C--15006103(+) GAACTGA/-GAGGG 6 -- int11Minor allele frequency- -:0.00CSA 2
    rs1480462731,2
    C--15006178(+) GGGCTC/GTGGGG 6 -- int10--------
    rs1416562241,2
    --15006184(+) TGGGGC/GCGTGG 6 -- int10--------
    rs1130806821,2
    C,F--15006466(+) TTGGGT/CAGGGG 6 -- int11Minor allele frequency- C:0.00CSA 1
    rs1133581541,2
    C--15006551(+) AAGGC-/TTTTTT 6 -- int11Minor allele frequency- T:0.00CSA 2
    rs1826117231,2
    --15006608(+) CCTTGA/GAGCCT 6 -- int10--------
    rs1397939711,2
    C--15006737(+) TCCTCA/GCAGGA 6 -- int10--------
    rs74379741,2
    C,F,A,H--15006807(+) GTGACC/GGCTCG 6 -- int119Minor allele frequency- N:0.00EA NA NS WA CSA 1004
    rs1415525801,2
    --15006969(+) CTTCTA/GCAAGG 6 -- int10--------

    HapMap Linkage Disequilibrium report for CPEB2 (15004298 - 15071777 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CPEB2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2437263CNV Deletion19546169
    nsv461280CNV Loss19166990
    nsv878711CNV Loss21882294
    nsv518661CNV Loss19592680
    esv29275CNV Loss19812545
    nsv829868CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610605    OMIM disorders: --


    Find genes that share disorders with CPEB2           About GenesLikeMe

    Genetic Association Database (GAD): CPEB2

    Export disorders for CPEB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CPEB2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CPEB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. CPEB2, a novel putative translational regulator in mouse haploid germ cells. (PubMed id 12672660)1, 3 Kurihara Y....Uesugi S. (Biol. Reprod. 2003)
    3. Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to the HIF-1alpha mRNA 3'-UTR and modulate HIF-1alpha protein expression. (PubMed id 18752464)1, 9 HAogele S....Katschinski D.M. (Biochem. J. 2009)
    4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (BMC Med. Genet. 2007)
    5. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    6. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PubMed id 17903303)4 O'Donnell C.J....Demissie S. (BMC Med. Genet. 2007)
    7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 132864 HGNC: 21745 AceView: CPEB2 Ensembl:ENSG00000137449 euGenes: HUgn132864
    ECgene: CPEB2 H-InvDB: CPEB2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CPEB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CPEB2 gene:
    Search GeneIP for patents involving CPEB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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