CPEB1 Gene
protein-coding GIFtS: 52
GCID: GC15M083211
|
|
cytoplasmic polyadenylation element binding protein 1
| |
Aliases
for CPEB1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytoplasmic Polyadenylation Element Binding Protein 11 2 | | HCPEB-11 | | CPEB1 2 3 | | FLJ132031 | | CPE-BP12 3 | | CEBP2 | | CPE-Binding Protein 12 3 | | Cytoplasmic Polyadenylation Element-Binding Protein 12 | | H-CEBP1 | | |
Export aliases for CPEB1 gene to outside databasesPrevious GC identifers: GC15M079015 GC15M076145 GC15M080796 GC15M080939 GC15M080940 GC15M081009 GC15M059482 |
Summaries
for CPEB1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CPEB1:
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highlyconserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteinsin Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resultingin their translation. Members of this protein family regulate translation of cyclin B1 during embryonic celldivisions. Multiple transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CPEB1_HUMAN, Q9BZB8Function: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translationinitiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmicpolyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation ofCPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in thetransport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationallydormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes localCPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stressgranules in the absence of stress
Gene Wiki entry for CPEB1
|
Genomic Views
for CPEB1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_077661.3
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CPEB1 gene promoter:
Elk-1 LCR-F1 Tal-1beta E47 AREB6 MZF-1 HFH-1 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CPEB1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPEB1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q25.2 Ensembl cytogenetic band: 15q25.2 HGNC cytogenetic band: 15q25.1CPEB1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M083211: view genomic region
(about GC identifiers)
Start:
|
83,211,951 bp from pter |
End:
|
83,317,612 bp from pter |
Size:
|
105,662 bases |
Orientation:
|
minus strand |
|
Proteins
for CPEB1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CPEB1_HUMAN, Q9BZB8 (See
protein sequence)Recommended Name: Cytoplasmic polyadenylation element-binding protein 1 Size: 566 amino acids; 62595 Da
Subunit: Interacts with kinesin, dynein, APLP1, APLP2, PAPD4/GLD2 and APP. Both phosphorylated and non phosphorylatedforms interact with APLP1 (By similarity)
Subcellular location: Cytoplasm, P-body. Cytoplasmic granule. Cell junction, synapse. Membrane. Cell junction, synapse,postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Note=Alsofound in stress granules. Recruited to stress granules (SGs) upon arsenite treatment. In dendrites (By similarity).Localizes in synaptosomes at dendritic synapses of neurons (By similarity). Strongly enriched in postsynaptic density(PSD) fractions (By similarity). Transported into dendrites in a microtubule-dependent fashion and colocalizes inmRNA-containing particles with TACC3, dynein and kinesin (By similarity). Membrane-associated (By similarity).Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1,TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity)
Secondary accessions: B7Z6C6 Q86W46 Q8IV41 Q9BZB7 Q9H8V5Alternative splicing: 4 isoforms: Q9BZB8-1 Q9BZB8-2 Q9BZB8-3 Q9BZB8-4 Explore the universe of human proteins at neXtProt for CPEB1: NX_Q9BZB8
Post-translational modifications:
Phosphorylated on serine/threonine residues by AURKA within positions 166 and 197. Phosphorylation anddephosphorylation on Thr-172 regulates cytoplasmic polyadenylation and translation of CPE-containing mRNAs.Phosphorylation on Thr-172 by AURKA and CAMK2A activates CPEB1. Phosphorylation on Thr-172 may be promoted by APLP1.Phosphorylation increases binding to RNA (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BZB8
CPEB1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001073001.1 NP_001073002.1 NP_001073003.1 NP_085097.3
ENSEMBL proteins: ENSP00000414187 ENSP00000457556 ENSP00000381591 ENSP00000457836 ENSP00000397526 ENSP00000457881 ENSP00000457364 ENSP00000261723 ENSP00000458081 ENSP00000454881 ENSP00000455044 ENSP00000455268 ENSP00000457137 ENSP00000381592
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
CPEB1 for ontologies About GeneDecksing
CPEB1 Antibody Products:
Assay Products for CPEB1: |
Protein
Domains /
Families
for CPEB1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CPEB1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BZB8ProtoNet protein and cluster: Q9BZB8 1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
UniProtKB/Swiss-Prot: CPEB1_HUMAN, Q9BZB8Domain: The 2 RRM domains and the C-terminal region mediate interaction with CPE-containing RNA (By similarity)Similarity: Belongs to the RRM CPEB familySimilarity: Contains 2 RRM (RNA recognition motif) domains |
Function
for CPEB1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CPEB1_HUMAN, Q9BZB8Function: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translationinitiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmicpolyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation ofCPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in thetransport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationallydormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes localCPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stressgranules in the absence of stress
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPEB1 (see all 5)
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CPEB1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Cpeb1tm1Rcht for CPEB1
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cpeb1):
CPEB1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CPEB1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Oocyte meiosis | | | 2 | Aurora A signaling | | | 3 | Dorso-ventral axis formation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for CPEB1
3 
Kegg Pathways (Kegg details for CPEB1):
CPEB1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPEB1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/81 Interacting proteins for CPEB1 (Q9BZB83 ENSP000004141874) via UniProtKB, MINT, STRING, and/or I2D (see all 81)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006397 | mRNA processing |
IEA | -- | | GO:0006417 | regulation of translation |
IEA | -- |
CPEB1 for ontologies About GeneDecksing
|
Drugs & Compounds
for CPEB1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CPEB1 for compounds About GeneDecksing
 Browse Tocris compounds for CPEB1
6 Novoseek chemical compound relationships for CPEB1 gene About this table
Search CenterWatch for drugs/clinical trials and news about CPEB1
|
Transcripts
for CPEB1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CPEB1 gene (4 alternative transcripts): NM_001079533.1 NM_001079534.1 NM_001079535.1 NM_030594.3 Unigene Cluster for CPEB1: Cytoplasmic polyadenylation element binding protein 1 Hs.547988 [show with all ESTs]Unigene Representative Sequence: BX64915918 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000569015(uc002bip.3) ENST00000450751(uc002biq.3 uc002bir.3 uc002bis.3 uc010uod.2 uc010uoe.2 uc010uof.2 uc002biv.3)
ENST00000563800(uc002bit.3 uc002biu.3) ENST00000398591 ENST00000562019
ENST00000423133 ENST00000568128 ENST00000564522 ENST00000261723 ENST00000568757
ENST00000570229 ENST00000570205 ENST00000568994 ENST00000569257 ENST00000567678
ENST00000566716 ENST00000563519 ENST00000398592
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPEB1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPEB1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): CPEB1 (NM_001079534) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CPEB1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPEB1 |
Additional cDNA sequence: AF329402.1 AF329403.1 AK023265.1 AK294280.1 AK300105.1 AK301728.1 AL832156.1 BC035348.1 BC050629.1 BX649159.1 10 DOTS entries: DT.95365025 DT.100752004 DT.433263 DT.100722696 DT.121021350 DT.121021850 DT.75154050 DT.100752005 DT.100752006 DT.121021941 24/3007 AceView cDNA sequences (see all 3007): BM888403 AA583869 BF663531 CR602312 AI688985 BC009407 BE277510 BX391083 BE905890 CB113570 BE266126 AI685465 CD105295 BE901871 AI243633 BF795910 BM853852 BF727297 AW163296 BM715948 BQ070359 BE893362 BM788251 BG422230
GeneLoc Exon Structure
|
Expression
for CPEB1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CPEB1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGGCCTGC
About this image
See CPEB1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CPEB1
SOURCE GeneReport for Unigene cluster: Hs.547988
UniProtKB/Swiss-Prot: CPEB1_HUMAN, Q9BZB8Tissue specificity: Isoform 1 is expressed in immature oocytes, ovary, brain and heart. Isoform 2 is expressed in brainand heart. Isoform 3 and isoform 4 are expressed in brain. Expressed in breast tumors and several tumor cell lines
SABiosciences Custom PCR Arrays for CPEB1
Primer
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Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB1 |
Orthologs
for CPEB1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CPEB1 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CPEB11 |
cytoplasmic polyadenylation element binding protein more |
80.06(n)
86.25(a) |
|
415326 XM_413713.3 XP_413713.2 |
lizard
(Anolis carolinensis) |
Reptilia |
CPEB16 |
-- |
78(a) |
1 → many |
GL343479.1(566791-612839) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.9842 |
Xenopus laevis cytoplasmic polyadenylation element more |
79.27(n) |
|
U14169.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zorba2 |
Orb/CPEB-related RNA-binding protein |
74.36(n) |
|
30702 AB011680.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
orb3 |
germ-cell development RNA binding |
59(a) |
|
3 94E9 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
cpb-33 |
-- |
44(a) |
|
I(5797307-5799860) -- |
ENSEMBL Gene Tree for CPEB1 (if available)
TreeFam Gene Tree for CPEB1 (if available) |
Paralogs
for CPEB1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CPEB1 gene
- CPEB22 CPEB42 ENSG000002608362 CPEB32
5 SIMAP similar genes for CPEB1 using alignment to 8 protein entries: CPEB1_HUMAN (see all proteins):CPEB 4 variant CPEB2 CPEB3 CPEB4 DKFZp686L03182
CPEB1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CPEB1
PGOHUM00000246883
|
Genomic Variants
for CPEB1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CPEB1 (83211951 - 83317612 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for CPEB1
6 CNVs: 72323 7075 10488 9266 0190 3972
5 Indels: 45374 61468 25569 102145 42400 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPEB1 |
|
Disorders
/ Diseases
for CPEB1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CPEB1 for disorders About GeneDecksing
OMIM gene information: 607342
OMIM disorders: --
7  diseases for CPEB1: About MalaCardschronic lymphocytic leukemia lymphocytic leukemia hermaphroditism leukemia
cervicitis retinitis neuronitis
Human Genome Epidemiology (HuGE) Navigator: CPEB1 (2 documents)
Export disorders for CPEB1 gene to outside databases
|
Publications
for CPEB1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CPEB1 gene, integrated from 9 sources (see all 78):
(articles sorted by number of sources associating them with CPEB1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein. (PubMed id 11223249)1, 2, 3 Welk J.F.... MacNicol A.M. (2001)
- The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules. (PubMed id 15731006)1, 2 Wilczynska A.... Weil D. (2005)
- Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1. (PubMed id 15966895)1, 2 Sasayama T.... Hirota T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation. (PubMed id 19141477)1, 9 Burns D.M. and Richter J.D. (2008)
- Expression of CPEB, GAPDH and U6snRNA in cervical and ovarian tissue during cancer development. (PubMed id 19161537)1, 9 Hansen C.N....Norrild B. (2009)
- CPEB1, a novel gene silenced in gastric cancer: a Dros ophila approach. (PubMed id 22052064)1 Caldeira J....Seruca R. (2012)
- Cytoplasmic polyadenylation element binding protein de ficiency stimulates PTEN and Stat3 mRNA translation and induces hepatic insulin resistance. (PubMed id 22253608)1 Alexandrov I.M....Richter J.D. (2012)
- Transient CPEB dimerization and translational control. (PubMed id 22456264)1 Lin C.L....Richter J.D. (2012)
|
External Searches for CPEB1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CPEB1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CPEB1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CPEB1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CPEB1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CPEB1 gene:
Search GeneIP for patents involving CPEB1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CPEB1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for CPEB1 | | OriGene shRNA RFP for CPEB1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPEB1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CPEB1 | | | OriGene Protein Over-expression Lysate for CPEB1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CPEB1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CPEB1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CPEB1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CPEB1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CPEB1 | | OriGene Custom Protein Services for CPEB1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CPEB1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CPEB1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPEB1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPEB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPEB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPEB1 |
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| | | | Search Tocris compounds for CPEB1 |
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 | | | CPEB1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPEB1 |
|  |  |  | | | | ThermoFisher Antibodies for CPEB1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPEB1 |
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