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CPAMD8 Gene

protein-coding   GIFtS: 49
GCID: GC19M017003

C3 And PZP-Like, Alpha-2-Macroglobulin Domain Containing...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
C3 And PZP-Like, Alpha-2-Macroglobulin Domain Containing 81 2
KIAA12833 5
K-CAP2
VIP2
Alpha-2 Macroglobulin Family Protein VIP2
C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 82

External Ids:    HGNC: 232281   Entrez Gene: 271512   Ensembl: ENSG000001601117   OMIM: 6088415   UniProtKB: Q8IZJ33   

Export aliases for CPAMD8 gene to outside databases

Previous GC identifers: GC19M016866 GC19M016867 GC07P009820


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CPAMD8 Gene:
CPAMD8 belongs to the complement component-3 (C3; MIM 120700)/alpha-2-macroglobulin (A2M; MIM 103950) family of
proteins, which are involved in innate immunity and damage control. Complement components recognize and eliminate
pathogens by direct binding or by mediating opsonization/phagocytosis and intracellular killing, and A2M is a
broad-spectrum protease inhibitor (Li et al., 2004 (PubMed 15177561)).(supplied by OMIM, Mar 2008)

GeneCards Summary for CPAMD8 Gene:
CPAMD8 (C3 and PZP-like, alpha-2-macroglobulin domain containing 8) is a protein-coding gene. GO annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is A2M.

summary for CPAMD8 Gene:
Vasoactive intestinal peptide (VIP) receptors are a group of Gs-protein-coupled receptors that are currently
divided into two subtypes; VPAC1 and VPAC2. They are widely distributed throughout the central nervous
system and are also found in peripheral organs including the liver, lung, intestine, skeletal muscle, heart
and kidney. VPAC1 and VPAC2 have diverse biological actions including promotion of neuronal survival,
regulation of glycogen metabolism, stimulation of prolactin release from the pituitary and catecholamine
release from the adrenal medulla, and inhibition of IL-2-mediated T-cell proliferation. The human genes
encoding VPAC1 and VPAC2 receptor have been located on chromosomes 3p22 and 7q36.3 respectively.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CPAMD8
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCPAMD8 promoter sequence
   Search Chromatin IP Primers for CPAMD8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CPAMD8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.12

CPAMD8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPAMD8 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M017003:  view genomic region     (about GC identifiers)

Start:
17,003,758 bp from pter      End:
17,137,625 bp from pter
Size:
133,868 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CPMD8_HUMAN, Q8IZJ3 (See protein sequence)
Recommended Name: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 precursor  
Size: 1885 amino acids; 206702 Da
Subunit: Interacts with heparin
Sequence caution: Sequence=BAC11400.1; Type=Erroneous initiation;
Secondary accessions: Q8NC09 Q9ULD7
Alternative splicing: 2 isoforms:  Q8IZJ3-1   Q8IZJ3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CPAMD8: NX_Q8IZJ3

Explore proteomics data for CPAMD8 at MOPED

Post-translational modifications: 

  • Proteolytically cleaved into 2 chains of about 70 and 130 kDa. The fragments are not connected by disulfide bonds1
  • Glycosylation2 at Asn117, Asn190, Asn267, Asn757, Asn1439
  • Modification sites at PhosphoSitePlus

  • See CPAMD8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056507.2  
    ENSEMBL proteins: 
     ENSP00000402505   ENSP00000471545   ENSP00000473216   ENSP00000469163   ENSP00000291440  
     ENSP00000373577  

    CPAMD8 Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online kits for CPAMD8 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 11):
     IPR002350 Kazal_dom
     IPR014756 Ig_E-set
     IPR001599 Macroglobln_a2
     IPR011626 A2M_comp
     IPR002890 A2M_N

    Graphical View of Domain Structure for InterPro Entry Q8IZJ3

    ProtoNet protein and cluster: Q8IZJ3

    3 Blocks protein domains:
    IPB001599 Alpha-2-macroglobulin
    IPB002890 Alpha-2-macroglobulin
    IPB009048 Alpha-macroglobulin


    UniProtKB/Swiss-Prot: CPMD8_HUMAN, Q8IZJ3
    Similarity: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family
    Similarity: Contains 1 Kazal-like domain


    Find genes that share domains with CPAMD8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CPMD8_HUMAN, Q8IZJ3
    Induction: Up-regulated by IL1B/interleukin-1 beta and IL6/interleukin-6

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004866endopeptidase inhibitor activity ----
    GO:0004867serine-type endopeptidase inhibitor activity IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CPAMD8           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CPAMD8

    miRNA
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    miRTarBase miRNAs that target CPAMD8:
    hsa-mir-335-5p (MIRT017990)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CPMD8_HUMAN, Q8IZJ3: Secreted (Probable). Cell membrane; Peripheral membrane protein; Extracellular side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular4
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space IEA--
    GO:0005886plasma membrane IEA--

    Find genes that share ontologies with CPAMD8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CPAMD8
    Interactions:

        Search GeneGlobe Interaction Network for CPAMD8

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for CPAMD8 (Q8IZJ33 ENSP000002914404) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DPP4P274873, ENSP000003537314I2D: score=1 STRING: ENSP00000353731
    SCTRP478723, ENSP000000191034I2D: score=2 STRING: ENSP00000019103
    ADCYAP1P185093I2D: score=1 
    --ENSP000002692004STRING: ENSP00000269200
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for CPAMD8 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    [D-p-Cl-Phe6,Leu17]-VIP Selective VIP receptor antagonist[102805-45-8]
    Bay 55-9837Potent and selective VPAC2 agonist[463930-25-8]
    VIP (6-28) (human, rat, porcine, bovine) VIP antagonist[69698-54-0]
    VIP (human, rat, mouse, rabbit, canine, porcine) Involved in neurotransmission, smooth muscle relaxation [40077-57-4]
    [Ala11,22,28]VIP Potent, highly selective VPAC1 agonist [291524-04-4]



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CPAMD8 gene: 
    NM_015692.2  

    Unigene Cluster for CPAMD8:

    C3 and PZP-like, alpha-2-macroglobulin domain containing 8
    Hs.631644  [show with all ESTs]
    Unigene Representative Sequence: NM_015692
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000443236(uc002nfb.3) ENST00000594249 ENST00000600235 ENST00000596224
    ENST00000597335 ENST00000602132 ENST00000598547 ENST00000598792 ENST00000601782
    ENST00000597709 ENST00000598104 ENST00000596572 ENST00000593739 ENST00000599287
    ENST00000595323 ENST00000593420 ENST00000602159 ENST00000291440(uc010xpj.1 uc002nfd.1)

    miRNA
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    GenScript: all cDNA clones in your preferred vector: CPAMD8 (NM_015692)
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    Primer
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      QuantiFast Probe-based Assays in human, mouse, rat CPAMD8

    Additional mRNA sequence: 

    AB033109.1 AK075099.1 AK092632.1 AY101765.1 BC067854.1 

    8 DOTS entries:

    DT.99950234  DT.100025239  DT.106740  DT.100025235  DT.100772000  DT.97784875  DT.100025233  DT.121477977 

    Selected AceView cDNA sequences (see all 86):

    AK124052 BM720454 BM723750 BF724694 CD244746 CA392885 CA388956 BF724846 
    CD243466 CA391121 AI683732 CA392927 BF726092 CA388683 CA388955 BG708853 
    CA389994 AI928636 BU633141 BQ181790 BG899872 BX384285 BQ001729 AI201464 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CPAMD8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTTGTGGG
    CPAMD8 Expression
    About this image

    CPAMD8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CPAMD8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.631644

    UniProtKB/Swiss-Prot: CPMD8_HUMAN, Q8IZJ3
    Tissue specificity: Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and
    small intestine

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPAMD8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CPAMD8 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia CPAMD81 C3 and PZP-like, alpha-2-macroglobulin domain containing more 85.57(n)
    85.5(a)
      484845  XM_005632735.1  XP_005632792.1 
    chicken
    (Gallus gallus)
    Aves CPAMD81 C3 and PZP-like, alpha-2-macroglobulin domain containing more 70.05(n)
    71.27(a)
      420138  XM_003642893.2  XP_003642941.2 
    lizard
    (Anolis carolinensis)
    Reptilia CPAMD86
    C3 and PZP-like, alpha-2-macroglobulin domain cont...
    69(a)
    1 ↔ 1
    GL344197.1(8946-58900)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cpamd81 C3 and PZP-like, alpha-2-macroglobulin domain containing more 64.08(n)
    65.73(a)
      100491045  XM_002934370.2  XP_002934416.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cpamd81 C3 and PZP-like, alpha-2-macroglobulin domain containing more 65.67(n)
    66.13(a)
      100151400  XM_003201057.2  XP_003201105.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mcr6
    Macroglobulin complement-related
    21(a)
    1 ↔ 1
    2L(8074117-8082982)


    ENSEMBL Gene Tree for CPAMD8 (if available)
    TreeFam Gene Tree for CPAMD8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CPAMD8 gene
    A2M2  C52  C32  C4B2  C4A2  A2ML12  PZP2  CD1092  
    5 SIMAP similar genes for CPAMD8 using alignment to 6 protein entries:     CPMD8_HUMAN (see all proteins):
    LOC340268    AGRN    DKFZp566D234    C4B    OVOS2

    Find genes that share paralogs with CPAMD8           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CPAMD8
    PGOHUM00000233125


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CPAMD8 (see all 3611)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22273551,2
    C,F,H--17003381(+) GATGTT/CGGCAG 1 -- int17Minor allele frequency- C:0.01NS CSA 662
    rs22273561,2
    C,F,H--17003405(+) TTGCAC/TGGGAC 1 -- int134Minor allele frequency- T:0.16NS EA NA CSA WA 5668
    rs1391104951,2
    --17003438(+) TGGCTA/GTGGAG 1 -- int10--------
    rs1855805831,2
    --17003512(+) ACACAC/GACACA 1 -- int10--------
    rs1395753861,2
    C--17003513(+) CACAG-/ACACACA 1 -- int10--------
    rs22273571,2
    C,F--17003553(+) AGGGAG/ATGGCA 1 -- int17Minor allele frequency- A:0.13NS NA EA 2510
    rs22273811,2
    C,F--17003559(+) TGGCAC/TAGGGC 1 -- int18Minor allele frequency- T:0.10NS NA EA 2518
    rs1498986211,2
    --17003638(+) CCTCAC/TTGGGT 1 -- int10--------
    rs1503683261,2
    C--17003715(+) ACATG-/CACACAC 1 -- int10--------
    rs7739011,2
    C,F,A,H--17003789(-) TGACAC/AGAATA 1 -- ut31 ese334Minor allele frequency- A:0.45MN NS EA NA WA CSA EU 4651

    HapMap Linkage Disequilibrium report for CPAMD8 (17003758 - 17137625 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CPAMD8 (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669422CNV Deletion23128226
    esv2718270CNV Deletion23290073
    esv2675257CNV Deletion23128226
    esv2718271CNV Deletion23290073
    nsv2426CNV Insertion18451855
    esv29414CNV Loss19812545
    nsv911174CNV Loss21882294
    dgv3755n71CNV Loss21882294
    nsv911175CNV Loss21882294
    nsv911169CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CPAMD8
    DNA2.0 Custom Variant and Variant Library Synthesis for CPAMD8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608841    OMIM disorders: --


    Find genes that share disorders with CPAMD8           About GenesLikeMe

    Genetic Association Database (GAD): CPAMD8
    Human Genome Epidemiology (HuGE) Navigator: CPAMD8 (4 documents)

    Export disorders for CPAMD8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CPAMD8 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with CPAMD8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)1, 4 Baranzini S.E....Oksenberg J.R. (Hum. Mol. Genet. 2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Identification and characterization of CPAMD8, a novel member of the complement 3/alpha2-macroglobulin family with a C-terminal Kazal domain. (PubMed id 15177561)1, 2 Li Z.-F.... Engvall E. (Genomics 2004)
    6. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1 Kenny E.E....Peter I. (PLoS Genet. 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    10. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27151 HGNC: 23228 AceView: CPAMD8 Ensembl:ENSG00000160111 euGenes: HUgn27151
    ECgene: CPAMD8 H-InvDB: CPAMD8

    (According to HUGE)
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    HUGE: KIAA1283

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CPAMD8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CPAMD8 gene:
    Search GeneIP for patents involving CPAMD8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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