Aliases for CPA6 Gene
External Ids for CPA6 Gene
The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome.[provided by RefSeq, Sep 2010]
GeneCards Summary for CPA6 Gene
CPA6 (Carboxypeptidase A6) is a Protein Coding gene. Diseases associated with CPA6 include epilepsy, familial temporal lobe, 5 and febrile seizures, familial, 11. GO annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is CPA3.
UniProtKB/Swiss-Prot for CPA6 Gene
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II.