Aliases for CPA6 Gene
External Ids for CPA6 Gene
Previous GeneCards Identifiers for CPA6 Gene
The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome.[provided by RefSeq, Sep 2010]
GeneCards Summary for CPA6 Gene
CPA6 (Carboxypeptidase A6) is a Protein Coding gene. Diseases associated with CPA6 include Epilepsy, Familial Temporal Lobe, 5 and Febrile Seizures, Familial, 11. GO annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPA3.
UniProtKB/Swiss-Prot for CPA6 Gene
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II.