Aliases for CPA4 Gene
External Ids for CPA4 Gene
Previous GeneCards Identifiers for CPA4 Gene
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]
GeneCards Summary for CPA4 Gene
CPA4 (Carboxypeptidase A4) is a Protein Coding gene. Diseases associated with CPA4 include richter's syndrome and silver-russell syndrome. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Pancreatic secretion. GO annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is CPA3.
UniProtKB/Swiss-Prot for CPA4 Gene
Metalloprotease that could be involved in the histone hyperacetylation pathway.