Aliases for CPA4 Gene
External Ids for CPA4 Gene
Previous GeneCards Identifiers for CPA4 Gene
This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008]
GeneCards Summary for CPA4 Gene
CPA4 (Carboxypeptidase A4) is a Protein Coding gene. Diseases associated with CPA4 include silver-russell syndrome and gliosarcoma. Among its related pathways are Transport to the Golgi and subsequent modification and Pancreatic secretion. GO annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPA3.
UniProtKB/Swiss-Prot for CPA4 Gene
Metalloprotease that could be involved in the histone hyperacetylation pathway.