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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX8A Gene

protein-coding   GIFtS: 53
GCID: GC11P063742

Cytochrome C Oxidase Subunit VIIIA (Ubiquitous)

(Previous names: cytochrome c oxidase subunit VIII, cytochrome c oxidase...)
(Previous symbol: COX8)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cytochrome C Oxidase Subunit VIIIA (Ubiquitous)1 2     COX8L2 3
COX81 2 3 5     COX2
Cytochrome C Oxidase Subunit 8A (Ubiquitous)1 2     COX8-22
Cytochrome C Oxidase Subunit VIII1 2     VIII2
Cytochrome C Oxidase Polypeptide VIII-Liver/Heart2 3     VIII-L2
Cytochrome C Oxidase Subunit 8-22 3     Cytochrome C Oxidase Subunit 8A, Mitochondrial2

External Ids:    HGNC: 22941   Entrez Gene: 13512   Ensembl: ENSG000001763407   OMIM: 1238705   UniProtKB: P101763   

Export aliases for COX8A gene to outside databases

Previous GC identifers: GC11P063518 GC11P063498 GC11P060070


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COX8A Gene:
The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of
electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical
gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which
perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in
number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be
involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
(provided by RefSeq, Jul 2008)

GeneCards Summary for COX8A Gene: 
COX8A (cytochrome c oxidase subunit VIIIA (ubiquitous)) is a protein-coding gene. Diseases associated with COX8A include malignant glioma, and huntington's disease, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include cytochrome-c oxidase activity. An important paralog of this gene is ENSG00000256100.

UniProtKB/Swiss-Prot: COX8A_HUMAN, P10176
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
oxidase in mitochondrial electron transport




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX8A gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B2   Olf-1   POU2F2   AREB6   POU2F1   POU2F1a   POU2F2B   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX8A promoter sequence
   Search SABiosciences Chromatin IP Primers for COX8A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX8A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12-q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q12-q13

COX8A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX8A gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P063742:  view genomic region     (about GC identifiers)

Start:
63,742,079 bp from pter      End:
63,744,015 bp from pter
Size:
1,937 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COX8A_HUMAN, P10176 (See protein sequence)
Recommended Name: Cytochrome c oxidase subunit 8A, mitochondrial precursor  
Size: 69 amino acids; 7579 Da
Subcellular location: Mitochondrion inner membrane
Secondary accessions: P15955

Explore the universe of human proteins at neXtProt for COX8A: NX_P10176

Explore proteomics data for COX8A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P10176

  • COX8A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COX8A Protein Expression
    REFSEQ proteins: NP_004065.1  
    ENSEMBL proteins: 
     ENSP00000321260  
    Reactome Protein details: P10176
    Human Recombinant Protein Products for COX8A: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane TAS--
    GO:0016021integral to membrane IEA--

    COX8A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comIV: Mitochondrial respiratory chain complex / Complex IV

    2 InterPro protein domains:
     IPR003205 Cyt_c_oxidase_su8
     IPR016070 Cyt_c_oxidase_su8/PSI_RC_su9

    Graphical View of Domain Structure for InterPro Entry P10176

    ProtoNet protein and cluster: P10176

    1 Blocks protein domain: IPB003205 Cytochrome oxidase c

    UniProtKB/Swiss-Prot: COX8A_HUMAN, P10176
    Similarity: Belongs to the cytochrome c oxidase VIII family


    COX8A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COX8A_HUMAN, P10176
    Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
    oxidase in mitochondrial electron transport

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity IEA--
         
    COX8A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for COX8A 
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    SwitchGear 3'UTR luciferase reporter plasmidCOX8A 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for COX8A About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Huntington's disease0.47
    Electron Transport Chain0.75
    Alzheimer's disease0.46
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
    Arachidonate Epoxygenase / Epoxide Hydrolase0.36
    4Cardiac muscle contraction
    Cardiac muscle contraction

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for COX8A
        Arachidonate Epoxygenase / Epoxide Hydrolase
    Electron Transport Chain


    4        Reactome Pathways for COX8A
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/7         Kegg Pathways  (Kegg details for COX8A) (see all 7):
        Oxidative phosphorylation
    Metabolic pathways
    Cardiac muscle contraction
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease


    COX8A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX8A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/23 Interacting proteins for COX8A (ENSP000003212604) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COX4I1ENSP000002534524STRING: ENSP00000253452
    COX5AENSP000003177804STRING: ENSP00000317780
    COX5BENSP000002584244STRING: ENSP00000258424
    COX6B1ENSP000002465544STRING: ENSP00000246554
    COX6CENSP000002975644STRING: ENSP00000297564
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006091generation of precursor metabolites and energy TAS2543673
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    COX8A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COX8A

    2 HMDB Compounds for COX8A    About this table
    CompoundSynonyms CAS #PubMed Ids
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    2 DrugBank Compounds for COX8A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Cholic Acid-- 81-25-4target--10592235
    N-Formylmethionine-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about COX8A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COX8A gene: 
    NM_004074.2  

    Unigene Cluster for COX8A:

    Cytochrome c oxidase subunit VIIIA (ubiquitous)
    Hs.743989  [show with all ESTs]
    Unigene Representative Sequence: CD555987
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000314133(uc001nye.3)

    miRNA
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    hsa-miR-433 hsa-miR-298 hsa-miR-3121-3p
    SwitchGear 3'UTR luciferase reporter plasmidCOX8A 3' UTR sequence
    Inhib. RNA
    Products:
         
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    GenScript: all cDNA clones in your preferred vector: COX8A (NM_004074)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX8A
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    Additional mRNA sequence: 

    AK311934.1 BC000501.1 BC063025.1 BT009803.1 CR407687.1 

    22 DOTS entries:

    DT.101971358  DT.100886580  DT.100045241  DT.120741946  DT.91673279  DT.100045240  DT.100886564  DT.219944 
    DT.100886572  DT.100886573  DT.100886558  DT.120741959  DT.100673331  DT.100886562  DT.120741903  DT.40107023 
    DT.100044586  DT.100044589  DT.120741910  DT.95149702  DT.95333829  DT.97856606 

    24/1333 AceView cDNA sequences (see all 1333):

    AA298765 BE887772 AI290988 BM828931 BI824009 BU859734 CB856902 BM351840 
    BM470037 CR617582 AI266283 BQ668709 BF438229 F25631 AA299923 AA363976 
    T08109 AA312389 BM423637 AI571351 BE872490 BE883148 BF873267 BX119271 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COX8A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGACCTCCT
    COX8A Expression
    About this image


    See COX8A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COX8A

    SOURCE GeneReport for Unigene cluster: Hs.743989
        SABiosciences Expression via Pathway-Focused PCR Arrays including COX8A: 
              Mitochondrial Energy Metabolism in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX8A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for COX8A gene from 1/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox8a1 , 5 cytochrome c oxidase, subunit VIIIa5
    cytochrome c oxidase subunit VIIIa1
    78.74(n)1
    68.12(a)1
      19 (5.28 cM)5
    128681  NM_007750.21  NP_031776.11 
     72151585 


    ENSEMBL Gene Tree for COX8A (if available)
    TreeFam Gene Tree for COX8A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COX8A gene
    ENSG000002561002  
    1 SIMAP similar gene for COX8A using alignment to 2 protein entries:     COX8A_HUMAN (see all proteins):
    COX8C

    COX8A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/107 SNPs in COX8A are shown (see all 107)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs680802151,2
    C--60073014(+) TGTGT-/GTGT  
      GTGTGT
    GTGTC
    1 -- ds50011Minor allele frequency- GTGTGTGTGT:0.00NA 2
    rs1926492381,2
    --63740185(+) TAGCCA/GGGCAT 1 -- us2k10--------
    rs778794571,2
    C--63740297(+) TCCAGAG/-CCTGG 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1828152541,2
    --63740312(+) AACAGC/TGCAAG 1 -- us2k10--------
    rs1874617551,2
    --63740379(+) GTAATC/TCCAGC 1 -- us2k10--------
    rs1486663091,2
    --63740578(+) GCAGGG/TTCGAA 1 -- us2k10--------
    rs1421524231,2
    C--63740590(+) GTGTGC/GAATAT 1 -- us2k10--------
    rs1140599061,2
    C,F--63740629(+) AGTGAC/TATCCG 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1468254671,2
    --63740634(+) CATCCA/GGGAAT 1 -- us2k10--------
    rs2015817501,2
    C--63740870(+) CGGAG-/GCCT  
            
    GCCTG
    1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COX8A (63742079 - 63744015 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for COX8A:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv1156n71CNV Loss21882294
    dgv1155n71CNV Loss21882294
    esv29993CNV Loss17803354
    nsv897639CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 123870    OMIM disorders: --

    7 diseases for COX8A:    About MalaCards
    malignant glioma    huntington's disease    hepatitis c    parkinson's disease
    hepatitis    alzheimer's disease    pancreatitis

    1 disease from the University of Copenhagen DISEASES database for COX8A:
    Malignant glioma

    COX8A for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): COX8A
    Human Genome Epidemiology (HuGE) Navigator: COX8A (1 document)

    Export disorders for COX8A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COX8A gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with COX8A)
        Utopia: connect your pdf to the dynamic
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    1. A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non- muscle tissues. (PubMed id 2543673)1, 2, 3 Rizzuto R.... Schon E.A. (1989)
    2. Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence. (PubMed id 2847943)1, 2, 3 van Kuilenburg A.B.P....van Beeumen J.J. (1988)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A third isoform of cytochrome c oxidase subunit VIII is present in mammals. (PubMed id 12909344)1, 9 Huettemann M.... Grossman L.I. (2003)
    6. HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
    7. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (2000)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1351 HGNC: 2294 AceView: COX8AandOTUB1 Ensembl:ENSG00000176340 euGenes: HUgn1351
    ECgene: COX8A Kegg: 1351 H-InvDB: COX8A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COX8A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for COX8A gene:
    Search GeneIP for patents involving COX8A

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