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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX7B2 Gene

protein-coding   GIFtS: 52
GCID: GC04M046652

Cytochrome C Oxidase Subunit VIIb2

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cytochrome C Oxidase Subunit VIIb21 2
Cytochrome C Oxidase Polypeptide VIIb22 3
Cytochrome C Oxidase Subunit 7B2, Mitochondrial2

External Ids:    HGNC: 243811   Entrez Gene: 1707122   Ensembl: ENSG000001705167   OMIM: 6098115   UniProtKB: Q8TF083   

Export aliases for COX7B2 gene to outside databases

Previous GC identifers: GC04M046807 GC04M047046 GC04M046586 GC04M046577 GC04M046431 GC04M046055


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for COX7B2 Gene: 
COX7B2 (cytochrome c oxidase subunit VIIb2) is a protein-coding gene. Diseases associated with COX7B2 include nasopharyngitis, and huntington's disease, and among its related super-pathways are Electron Transport Chain and Metabolism. GO annotations related to this gene include cytochrome-c oxidase activity. An important paralog of this gene is COX7B.

UniProtKB/Swiss-Prot: CX7B2_HUMAN, Q8TF08
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
oxidase in mitochondrial electron transport




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_006238.11  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX7B2 gene promoter:
         Oct-B1   SRF   oct-B3   oct-B2   Pbx1a   SRF (504 AA)   AP-4   POU2F2   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX7B2 promoter sequence
   Search SABiosciences Chromatin IP Primers for COX7B2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX7B2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p12   Ensembl cytogenetic band:  4p12   HGNC cytogenetic band: 4p12

COX7B2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX7B2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M046652:  view genomic region     (about GC identifiers)

Start:
46,736,844 bp from pter      End:
46,911,252 bp from pter
Size:
174,409 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CX7B2_HUMAN, Q8TF08 (See protein sequence)
Recommended Name: Cytochrome c oxidase subunit 7B2, mitochondrial precursor  
Size: 81 amino acids; 9077 Da
Subcellular location: Mitochondrion inner membrane (By similarity)
Sequence caution: Sequence=AAH35923.1; Type=Erroneous initiation; Sequence=AAI07856.1; Type=Erroneous initiation;
Sequence=AAL75946.1; Type=Erroneous initiation;
Secondary accessions: Q32Q40

Explore the universe of human proteins at neXtProt for COX7B2: NX_Q8TF08

Explore proteomics data for COX7B2 at MOPED 

COX7B2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

COX7B2 Protein Expression

REFSEQ proteins: NP_570972.2  
ENSEMBL proteins: 
 ENSP00000379784   ENSP00000347799   ENSP00000423519   ENSP00000305964   ENSP00000437439  

Human Recombinant Protein Products for COX7B2: 
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Novus Biologicals COX7B2 Lysate
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Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005746mitochondrial respiratory chain IEA--
GO:0016021integral to membrane IEA--

COX7B2 for ontologies           About GeneDecksing



COX7B2 Antibody Products: 
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LSBio Antibodies in human, mouse, rat for COX7B2 

Assay Products for COX7B2: 
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Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
comIV: Mitochondrial respiratory chain complex / Complex IV

2 InterPro protein domains:
 IPR023272 Cyt_c_oxidase_suVIIB_dom
 IPR008433 Cyt_c_oxidase_suVIIB

Graphical View of Domain Structure for InterPro Entry Q8TF08

ProtoNet protein and cluster: Q8TF08

1 Blocks protein domain: IPB008433 Cytochrome C oxidase chain VIIB

UniProtKB/Swiss-Prot: CX7B2_HUMAN, Q8TF08
Similarity: Belongs to the cytochrome c oxidase VIIb family


COX7B2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CX7B2_HUMAN, Q8TF08
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
oxidase in mitochondrial electron transport

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004129cytochrome-c oxidase activity IEA--
     
COX7B2 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for COX7B2 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COX7B2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX7B2 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COX7B2 

miRNA
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Inhib. RNA
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QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COX7B2

Gene Editing
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Sirion Biotech Customized adenovirus for overexpression of COX7B2

Clone
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OriGene ORF clones in mouse, rat for COX7B2
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GenScript: all cDNA clones in your preferred vector: COX7B2 (NM_130902)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX7B2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX7B2
Sirion Biotech Customized lentivirus for stable overexpression of COX7B2 
                     Customized lentivirus expression plasmids for stable overexpression of COX7B2 

Cell Line
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Search LifeMap BioReagents cell lines for COX7B2
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7B2


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for COX7B2 About                                                                                                See pathways by source

SuperPathContained pathways About
1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Oxidative phosphorylation0.64
Alzheimer's disease0.46
Parkinson's disease0.61
Non-alcoholic fatty liver disease (NAFLD)0.41
Huntington's disease0.47
2Metabolism
Metabolic pathways0.40
3Cardiac muscle contraction
Cardiac muscle contraction
4AMPK Enzyme Complex Pathway
AMPK Enzyme Complex Pathway

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for COX7B2
    AMPK Enzyme Complex Pathway


5/7         Kegg Pathways  (Kegg details for COX7B2) (see all 7):
    Oxidative phosphorylation
Metabolic pathways
Cardiac muscle contraction
Non-alcoholic fatty liver disease (NAFLD)
Alzheimer's disease


COX7B2 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX7B2

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

5/14 Interacting proteins for COX7B2 (ENSP000003059644) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
InteractantInteraction Details
GeneCardExternal ID(s)
MT-CO1ENSP000003544994STRING: ENSP00000354499
COX5AENSP000003177804STRING: ENSP00000317780
MT-CO2ENSP000003548764STRING: ENSP00000354876
MT-CO3ENSP000003549824STRING: ENSP00000354982
COX6CENSP000002975644STRING: ENSP00000297564
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for COX7B2 (CX7B2)

2 HMDB Compounds for COX7B2    About this table
CompoundSynonyms CAS #PubMed Ids
OxygenOxygen (see all 5)7782-44-7--
WaterDihydrogen oxide (see all 2)7732-18-5--

Search CenterWatch for drugs/clinical trials and news about COX7B2 / CX7B2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for COX7B2 gene: 
NM_130902.2  

Unigene Cluster for COX7B2:

Cytochrome c oxidase subunit VIIb2
Hs.479656  [show with all ESTs]
Unigene Representative Sequence: BI829607
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000396533(uc010ige.3) ENST00000355591(uc003gxf.3) ENST00000505102
ENST00000302930 ENST00000543208

miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COX7B2
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate COX7B2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for COX7B2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COX7B2
Clone
Products:
     
OriGene clones in human, mouse for COX7B2 (see all 7)
OriGene ORF clones in mouse, rat for COX7B2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: COX7B2 (NM_130902)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX7B2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX7B2
Sirion Biotech Customized lentivirus for stable overexpression of COX7B2 
                     Customized lentivirus expression plasmids for stable overexpression of COX7B2 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for COX7B2
OriGene qSTAR qPCR primer pairs in human, mouse for COX7B2
SABiosciences RT2 qPCR Primer Assay in human, mouse / rat COX7B2
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX7B2
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX7B2

Additional mRNA sequence: 

AF125109.1 BC035923.1 BC107855.1 

5 DOTS entries:

DT.97783069  DT.311366  DT.92424831  DT.92424835  DT.95365661 

24/46 AceView cDNA sequences (see all 46):

AA909863 BM800781 AA910035 AA960902 AA971256 AI419946 AA935137 AI040938 
NM_130902 AW664696 AI025233 AF125109 BG187393 AA431383 BI829607 BG207061 
BC035923 BG207062 AI126605 AA781167 AW304005 BG198733 AW663461 AI632188 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for COX7B2    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP1:                                    
SP2:              -                     


ECgene alternative splicing isoforms for COX7B2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

COX7B2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TAAGCACTCT
COX7B2 Expression
About this image


See COX7B2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COX7B2

SOURCE GeneReport for Unigene cluster: Hs.479656
    SABiosciences Custom PCR Arrays for COX7B2
Primer
Products:
OriGene qPCR primer pairs and template standards for COX7B2
OriGene qSTAR qPCR primer pairs in human, mouse for COX7B2
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX7B2
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX7B2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7B2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for COX7B2 gene from 2/7 species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cox7b25 cytochrome c oxidase subunit VIIb2   --   5 (37.98 cM) 71442824 
chicken
(Gallus gallus)
Aves --
--
51(a)
1 → many
4(12862011-12864443)


ENSEMBL Gene Tree for COX7B2 (if available)
TreeFam Gene Tree for COX7B2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for COX7B2 gene
COX7B2  
1 SIMAP similar gene for COX7B2 using alignment to 2 protein entries:     CX7B2_HUMAN (see all proteins):
COX7B

COX7B2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/3532 SNPs in COX7B2 are shown (see all 3532)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 4 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1482149881,2
--46736417(+) TAGGAC/TAGCTC 1 -- ds50010--------
rs99952201,2
C,F--46736481(+) AATGAG/AGAGCA 1 -- ds50016Minor allele frequency- A:0.19WA CSA NA EA 364
rs1919304171,2
--46736652(+) TTCCAC/GCCAAA 1 -- ds50010--------
rs1820974171,2
--46736669(+) AATTTG/TTAAAT 1 -- ds50010--------
rs1868587001,2
--46736737(+) ATACAC/TGTTTT 1 -- ds50010--------
rs117360081,2
C,F,H--46736853(+) TAAAGA/TTTTAA 1 -- ut31 ese310Minor allele frequency- T:0.20NS EA NA WA 782
rs1412232741,2
--46736877(+) TTTTCA/CATTGT 1 -- ut310--------
rs1138325211,2
C--46736964(+) GATGGT/ATACTG 2 /* /Y --1Minor allele frequency- A:0.50CSA 2
rs2009581051,2
--46737000(+) CTGCCA/GACAGG 2 V syn10--------
rs1408221191,2
C,F--46737040(+) TGGCTG/ATAAAC 2 /T /I mis11Minor allele frequency- A:0.00NA 4550

HapMap Linkage Disequilibrium report for COX7B2 (46736844 - 46911252 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10/12 variations for COX7B2 (see all 12):    About this table     
Variant IDTypeSubtypePubMed ID
esv2727525CNV Deletion23290073
esv2410412CNV Deletion18987734
esv2450256CNV Deletion19546169
esv2657595CNV Deletion23128226
esv2727526CNV Deletion23290073
esv2666146CNV Deletion23128226
esv2672767CNV Deletion23128226
nsv291043CNV Insertion16902084
nsv292736CNV Insertion16902084
esv273230CNV Insertion20981092

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing COX7B2
DNA2.0 Custom Variant and Variant Library Synthesis for COX7B2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 609811    OMIM disorders: --

5 diseases for COX7B2:    About MalaCards
nasopharyngitis    huntington's disease    parkinson's disease    alzheimer's disease
prostatitis


COX7B2 for disorders           About GeneDecksing


Congresses - knowledge worth sharing:  
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
Genetic Association Database (GAD): COX7B2
Human Genome Epidemiology (HuGE) Navigator: COX7B2 (1 document)

Export disorders for COX7B2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for COX7B2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with COX7B2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A rare polymorphism of the COX7B2 gene in a Cantonese family with nasopharyngeal carcinoma. (PubMed id 15623157)1, 2, 3, 9 Liang H.... Zeng Y. (2004)
  2. Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (2008)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
  5. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
  6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  8. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 170712 HGNC: 24381 AceView: COX7B2 Ensembl:ENSG00000170516 euGenes: HUgn170712
ECgene: COX7B2 Kegg: 170712 H-InvDB: COX7B2

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for COX7B2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for COX7B2 gene:
Search GeneIP for patents involving COX7B2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore Custom Antibody & Bulk Services
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 OriGene Antibodies for COX7B2   OriGene RNAi products in human, mouse, rat for COX7B2  
 OriGene qPCR primer pairs and template standards for COX7B2   OriGene Protein Over-expression Lysate for COX7B2  
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 OriGene Custom Antibody Services for COX7B2   OriGene Custom Protein Services for COX7B2  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COX7B2
 QIAGEN SeqTarget long-range PCR primers for resequencing COX7B2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX7B2
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COX7B2
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 GenScript Custom Purified and Recombinant Proteins Services for COX7B2 GenScript cDNA clones with any tag delivered in your preferred vector for COX7B2
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 Regulatory tfbs in COX7B2 promoter
 Search Chromatin IP Primers for COX7B2
 RT2 qPCR Primer Assay in human, mouse / rat COX7B2
 Search GNC Networks for COX7B2
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 Search Tocris compounds for COX7B2 (CX7B2)
 Browse Sino Biological Proteins and Antibodies
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 COX7B2 antibodies
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 See all of Abcam's Antibodies, Kits and Proteins for COX7B2
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 Browse ProSpec Recombinant Proteins




 Browse Proteins at Cloud-Clone Corp.
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 Search LifeMap BioReagents cell lines for COX7B2
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7B2
 Browse SwitchGear 3'UTR luciferase reporter plasmids for COX7B2
 SwitchGear Promoter luciferase reporter plasmids for COX7B2
 ThermoFisher Antibody for COX7B2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX7B2
 inGenious Targeting Laboratory - Custom generated mouse model solutions for COX7B2
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COX7B2
Customized:
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 lentivirus expression plasmids for stable overexpression of COX7B2
 adenovirus for overexpression of COX7B2
 LSBio Antibodies in human, mouse, rat for COX7B2
Customized transgenic rodents for:
 Humanization
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 Tissue-specific gene expresssion
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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