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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX7B Gene

protein-coding   GIFtS: 59
GCID: GC0XP077154

Cytochrome C Oxidase Subunit VIIb

Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cytochrome C Oxidase Subunit VIIb1 2
Cytochrome C Oxidase Polypeptide VIIb2 3
APLCC2
Cytochrome C Oxidase Subunit 7B, Mitochondrial2
Cytochrome-C Oxidase Chain VIIb2

External Ids:    HGNC: 22911   Entrez Gene: 13492   Ensembl: ENSG000001311747   OMIM: 3008855   UniProtKB: P243113   

Export aliases for COX7B gene to outside databases

Previous GC identifers: GC0XP072700 GC0XP074116 GC0XP075196 GC0XP075910 GC0XP076961 GC0XP077041 GC0XP070740


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COX7B Gene:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron
transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic
subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The
mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in
the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to
bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2,
20 and 22. (provided by RefSeq, Jun 2011)

GeneCards Summary for COX7B Gene: 
COX7B (cytochrome c oxidase subunit VIIb) is a protein-coding gene. Diseases associated with COX7B include huntington's disease, and parkinson's disease, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include cytochrome-c oxidase activity. An important paralog of this gene is COX7B2.

UniProtKB/Swiss-Prot: COX7B_HUMAN, P24311
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in
vertebrates

Gene Wiki entry for COX7B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX7B gene promoter:
         POU2F1   POU2F1a   TGIF   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX7B promoter sequence
   Search SABiosciences Chromatin IP Primers for COX7B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq21.1   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

COX7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX7B gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP077154:  view genomic region     (about GC identifiers)

Start:
77,154,935 bp from pter      End:
77,162,870 bp from pter
Size:
7,936 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COX7B_HUMAN, P24311 (See protein sequence)
Recommended Name: Cytochrome c oxidase subunit 7B, mitochondrial precursor  
Size: 80 amino acids; 9161 Da
Subcellular location: Mitochondrion inner membrane (By similarity)
Secondary accessions: B2R4M3 Q6ICR1

Explore the universe of human proteins at neXtProt for COX7B: NX_P24311

Explore proteomics data for COX7B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P24311

  • COX7B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COX7B Protein Expression
    REFSEQ proteins: NP_001857.1  
    ENSEMBL proteins: 
     ENSP00000417656  
    Reactome Protein details: P24311
    Human Recombinant Protein Products for COX7B: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005746mitochondrial respiratory chain IEA--
    GO:0016021integral to membrane IEA--

    COX7B for ontologies           About GeneDecksing



    COX7B Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comIV: Mitochondrial respiratory chain complex / Complex IV

    2 InterPro protein domains:
     IPR023272 Cyt_c_oxidase_suVIIB_dom
     IPR008433 Cyt_c_oxidase_suVIIB

    Graphical View of Domain Structure for InterPro Entry P24311

    ProtoNet protein and cluster: P24311

    1 Blocks protein domain: IPB008433 Cytochrome C oxidase chain VIIB

    UniProtKB/Swiss-Prot: COX7B_HUMAN, P24311
    Similarity: Belongs to the cytochrome c oxidase VIIb family


    COX7B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COX7B_HUMAN, P24311
    Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
    oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in
    vertebrates

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity IEA--
         
    COX7B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for COX7B:
     Increased circadian period len  Synthetic lethal with Ras 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cox7b):
     embryogenesis  reproductive system 

    COX7B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for COX7B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COX7B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX7B 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate COX7B:
    hsa-miR-607
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for COX7B About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Huntington's disease0.47
    Electron Transport Chain0.75
    Alzheimer's disease0.46
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3Cardiac muscle contraction
    Cardiac muscle contraction
    4AMPK Enzyme Complex Pathway
    AMPK Enzyme Complex Pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for COX7B
        AMPK Enzyme Complex Pathway

    1 BioSystems Pathway for COX7B
        Electron Transport Chain


    4        Reactome Pathways for COX7B
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/7         Kegg Pathways  (Kegg details for COX7B) (see all 7):
        Oxidative phosphorylation
    Metabolic pathways
    Cardiac muscle contraction
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease


    COX7B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX7B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/25 Interacting proteins for COX7B (P243113 ENSP000004176564) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYBP102423I2D: score=1 
    COX4I1ENSP000002534524STRING: ENSP00000253452
    COX7A2LENSP000002343014STRING: ENSP00000234301
    COX8AENSP000003212604STRING: ENSP00000321260
    UQCRC2ENSP000002683794STRING: ENSP00000268379
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007417central nervous system development IMP--
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    COX7B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COX7B

    2 HMDB Compounds for COX7B    About this table
    CompoundSynonyms CAS #PubMed Ids
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    2 DrugBank Compounds for COX7B    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Cholic Acid-- 81-25-4target--10592235
    N-Formylmethionine-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about COX7B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COX7B gene: 
    NM_001866.2  

    Unigene Cluster for COX7B:

    Cytochrome c oxidase subunit VIIb
    Hs.522699  [show with all ESTs]
    Unigene Representative Sequence: BG179412
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373335 ENST00000481445(uc004ecu.1) ENST00000475465

    miRNA
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    hsa-miR-607
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    Additional mRNA sequence: 

    AK311879.1 BC018386.1 BT009767.1 CR450332.1 CR542124.1 Z14244.1 

    17 DOTS entries:

    DT.452860  DT.95337838  DT.100666783  DT.121301147  DT.95337846  DT.121301169  DT.92441857  DT.97859158 
    DT.101976238  DT.98131771  DT.95337803  DT.100824906  DT.121430977  DT.121635024  DT.92441853  DT.95337835 
    DT.91849803 

    24/344 AceView cDNA sequences (see all 344):

    AI719097 AJ709363 AI189185 F17677 BM785318 CR542124 BM781812 AI799736 
    BI222310 AW005526 F35499 F27273 BX505966 AI139984 F25447 AI278272 
    AA363970 AV682604 BG033616 CR450332 C05612 CD676651 H49486 CD676950 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for COX7B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5
    SP1:                          -           -         
    SP2:                    -     -           -         
    SP3:                                      -         
    SP4:                    -     -                     


    ECgene alternative splicing isoforms for COX7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COX7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACATATGTA
    COX7B Expression
    About this image


    See COX7B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COX7B

    SOURCE GeneReport for Unigene cluster: Hs.522699
        SABiosciences Expression via Pathway-Focused PCR Array including COX7B: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for COX7B gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox7b1 , 5 cytochrome c oxidase subunit VIIb1, 5 85(n)1
    78.75(a)1
      X (47.36 cM)5
    661421  NM_025379.21  NP_079655.11 
     1060157005 
    chicken
    (Gallus gallus)
    Aves --
    --
    56(a)
    1 → many
    4(12862011-12864443)
    African clawed frog
    (Xenopus laevis)
    Amphibia AW635929.12   -- 73.4(n)    AW635929.1 


    ENSEMBL Gene Tree for COX7B (if available)
    TreeFam Gene Tree for COX7B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COX7B gene
    COX7B22  
    1 SIMAP similar gene for COX7B using alignment to 1 protein entry:     COX7B_HUMAN:
    COX7B2

    COX7B for paralogs           About GeneDecksing


    5/11 Pseudogenes.org Pseudogenes for COX7B (see all 11)
    PGOHUM00000238476 PGOHUM00000242439 PGOHUM00000242879 PGOHUM00000239744 PGOHUM00000244317


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/106 SNPs in COX7B are shown (see all 106)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1836082051,2
    --77124143(+) CAAAAC/TGTTAC 1 -- us2k10--------
    rs1881489351,2
    --77124343(+) GGAGAC/TTGACT 1 -- us2k10--------
    rs1929129151,2
    --77124676(+) AAGCAG/TTTAGT 1 -- us2k10--------
    rs1838247161,2
    --77124791(+) TGGGAC/TAGGTC 1 -- us2k10--------
    rs1866986941,2
    --77124892(+) CTGGGA/GTTAGA 1 -- us2k10--------
    rs1911607261,2
    --77124956(+) TTGCCA/GTGTTG 1 -- us2k10--------
    rs2005627931,2
    C--77124982(+) TCTTT-/TTTTC 
            
    TTTCT
    1 -- us2k10--------
    rs2010634511,2
    --77124999(+) TTCTT-/TTCTTTTT 1 -- us2k10--------
    rs1847958331,2
    --77125032(+) GCTCTA/GTCACC 1 -- us2k10--------
    rs1892582931,2
    --77125155(+) ACGCCC/TAGCTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COX7B (77154935 - 77162870 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for COX7B:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv511668CNV Loss21212237


    Human Gene Mutation Database (HGMD): COX7B
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing COX7B
    DNA2.0 Custom Variant and Variant Library Synthesis for COX7B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300885    OMIM disorders: --

    UniProtKB/Swiss-Prot: COX7B_HUMAN, P24311
  • Aplasia cutis congenita, reticulolinear, with microcephaly, facial dysmorphism and other congenital
    anomalies (APLCC) [MIM:300887]: A distinct form of aplasia cutis congenita presenting as multiple linear skin
    defects on the face and neck associated with poor growth, microcephaly, and facial dysmorphism. Additional
    features include intellectual disability, nail dystrophy, short stature and cardiac abnormalities. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • 3 diseases for COX7B:    About MalaCards
    huntington's disease    parkinson's disease    alzheimer's disease


    COX7B for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for COX7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COX7B gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with COX7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of a cDNA specifying subunit VIIb of human cytochrome c oxidase. (PubMed id 8382530)1, 2, 3 Sadlock J.E.... Schon E.A. (1993)
    2. Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease. (PubMed id 23122588)1, 2 Indrieri A.... Franco B. (2012)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both 'heart-type' and 'liver-type' isoforms of subunit VIIa in human heart. (PubMed id 1309697)1, 2 van Kuilenburg A.B.P....Muijsers A.O. (1992)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. Interleukin-24 mediates apoptosis in human B-cells thr ough early activation of cell cycle arrest followed by late induction of the mit ochondrial apoptosis pathway. (PubMed id 22860893)1 Hadife N....Dalloul A. (2013)
    8. HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Novel insights into the assembly and function of huma n nuclear-encoded cytochrome c oxidase subunits 4, 5a, 6a, 7a and 7b. (PubMed id 20307258)1 Fornuskova D....Zeman J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1349 HGNC: 2291 AceView: COX7B Ensembl:ENSG00000131174 euGenes: HUgn1349
    ECgene: COX7B Kegg: 1349 H-InvDB: COX7B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COX7B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COX7B gene:
    Search GeneIP for patents involving COX7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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