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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX7A2 Gene

protein-coding   GIFtS: 55
GCID: GC06M075947

Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (Liver)

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (Liver)1 2     COXVIIa-L2
Cytochrome C Oxidase Subunit VIIa-L2 3     VIIAL2
Cytochrome C Oxidase Subunit VIIa-Liver/Heart2 3     Cytochrome C Oxidase Polypeptide 7A2, Mitochondrial2
Cytochrome C Oxidase Subunit VIIaL2 3     Cytochrome C Oxidase Polypeptide VIIa-Liver/Heart2
COX7AL2 3     Cytochrome C Oxidase Subunit 7A2, Mitochondrial2
COX7AL12     Hepatic Cytochrome-C Oxidase Chain VIIa2
COXVIIAL2     

External Ids:    HGNC: 22881   Entrez Gene: 13472   Ensembl: ENSG000001126957   OMIM: 1239965   UniProtKB: P144063   

Export aliases for COX7A2 gene to outside databases

Previous GC identifers: GC06M075895 GC06M075943 GC06M076004 GC06M073146


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COX7A2 Gene:
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron
transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three
catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The
mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function
in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit
VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2,
subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related
protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related
pseudogenes have been identified on chromosomes 4 and 14. (provided by RefSeq, Oct 2009)

GeneCards Summary for COX7A2 Gene: 
COX7A2 (cytochrome c oxidase subunit VIIa polypeptide 2 (liver)) is a protein-coding gene. Diseases associated with COX7A2 include barrett's adenocarcinoma, and hepatitis, and among its related super-pathways are Electron Transport Chain. GO annotations related to this gene include electron carrier activity and cytochrome-c oxidase activity. An important paralog of this gene is COX7A1.

UniProtKB/Swiss-Prot: CX7A2_HUMAN, P14406
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
oxidase in mitochondrial electron transport

Gene Wiki entry for COX7A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007299.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX7A2 gene promoter:
         SREBP-1c   CUTL1   YY1   C/EBPalpha   SREBP-1b   AREB6   SREBP-1a   HFH-1   COMP1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX7A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for COX7A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX7A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q12   Ensembl cytogenetic band:  6q14.1   HGNC cytogenetic band: 6q14.1

COX7A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX7A2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M075947:  view genomic region     (about GC identifiers)

Start:
75,947,391 bp from pter      End:
75,960,039 bp from pter
Size:
12,649 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CX7A2_HUMAN, P14406 (See protein sequence)
Recommended Name: Cytochrome c oxidase subunit 7A2, mitochondrial precursor  
Size: 83 amino acids; 9396 Da
Subunit: Interacts with PET100
Subcellular location: Mitochondrion inner membrane
Sequence caution: Sequence=CAI19899.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B2R5E1 Q3MIH5 Q5TF59 Q6FGI2

Explore the universe of human proteins at neXtProt for COX7A2: NX_P14406

Explore proteomics data for COX7A2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P14406

  • COX7A2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COX7A2 Protein Expression
    REFSEQ proteins: NP_001856.2  
    ENSEMBL proteins: 
     ENSP00000359098   ENSP00000359106   ENSP00000421969   ENSP00000425951   ENSP00000422979  
     ENSP00000423432   ENSP00000421193   ENSP00000230459  

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane ----
    GO:0005746mitochondrial respiratory chain IEA--

    COX7A2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comIV: Mitochondrial respiratory chain complex / Complex IV

    1 InterPro protein domain:
     IPR003177 Cyt_c_oxidase_su7a

    Graphical View of Domain Structure for InterPro Entry P14406

    ProtoNet protein and cluster: P14406

    1 Blocks protein domain: IPB003177 Cytochrome c oxidase

    UniProtKB/Swiss-Prot: CX7A2_HUMAN, P14406
    Similarity: Belongs to the cytochrome c oxidase VIIa family


    COX7A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CX7A2_HUMAN, P14406
    Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal
    oxidase in mitochondrial electron transport

         Genatlas biochemistry entry for COX7A2:
    cytochrome c oxidase,subunit VIIa,polypeptide 2,liver,pseudogene,

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity IEA--
    GO:0009055electron carrier activity IEA--
         
    COX7A2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for COX7A2 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for COX7A2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Electron Transport Chain0.75
    Huntington's disease0.47
    Oxidative phosphorylation0.64
    Alzheimer's disease0.46
    Parkinson's disease0.61
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Cardiac muscle contraction
    Cardiac muscle contraction
    3AMPK Enzyme Complex Pathway
    AMPK Enzyme Complex Pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for COX7A2
        AMPK Enzyme Complex Pathway

    1 BioSystems Pathway for COX7A2
        Electron Transport Chain


    5/6         Kegg Pathways  (Kegg details for COX7A2) (see all 6):
        Oxidative phosphorylation
    Cardiac muscle contraction
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    COX7A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX7A2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/11 Interacting proteins for COX7A2 (P144063 ENSP000002304594) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MT-CO2P004033, ENSP000003548764I2D: score=1 STRING: ENSP00000354876
    UBCENSP000003448184STRING: ENSP00000344818
    TCF3ENSP000002629654STRING: ENSP00000262965
    UQCRC1ENSP000002034074STRING: ENSP00000203407
    COX5BENSP000002584244STRING: ENSP00000258424
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COX7A2 (CX7A2)

    2 HMDB Compounds for COX7A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    Search CenterWatch for drugs/clinical trials and news about COX7A2 / CX7A2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COX7A2 gene: 
    NM_001865.3  

    Unigene Cluster for COX7A2:

    Cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
    Hs.70312  [show with all ESTs]
    Unigene Representative Sequence: BQ214619
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370081 ENST00000370089 ENST00000459637 ENST00000509698 ENST00000460985
    ENST00000472311 ENST00000377978 ENST00000481061 ENST00000230459(uc021zbx.1 uc003phv.2)


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    Additional mRNA sequence: 

    AK312154.1 BC100852.1 BC100853.1 BC100854.2 BC101826.1 BC101828.1 BC133654.1 CR407646.1 
    CR542125.1 HE647861.1 NR_029466.1 X15822.1 

    16 DOTS entries:

    DT.100685862  DT.449957  DT.95123003  DT.121332988  DT.91902187  DT.100877191  DT.121263463  DT.121333009 
    DT.100683359  DT.121332995  DT.100718144  DT.100877194  DT.100877195  DT.100877197  DT.91762350  DT.92355392 

    24/567 AceView cDNA sequences (see all 567):

    BM844217 AA573454 AA314810 AW085609 AA452437 CK299882 BX956596 AA384259 
    BF445123 CR407646 BG291563 BE537768 AI687033 AW340963 X15822 BQ675372 
    BM785087 CD108239 BF725549 CR542125 BM684755 AI458658 BM850329 AI921713 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for COX7A2    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b
    SP1:        -                             -     -                           
    SP2:                                      -     -           -               
    SP3:                                            -           -               
    SP4:                                      -     -                           
    SP5:                                                                        


    ECgene alternative splicing isoforms for COX7A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COX7A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    COX7A2 Expression
    About this image


    See COX7A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COX7A2

    SOURCE GeneReport for Unigene cluster: Hs.70312
        SABiosciences Expression via Pathway-Focused PCR Arrays including COX7A2: 
              Mitochondrial Energy Metabolism in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7A2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for COX7A2 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox7a21 , 5 cytochrome c oxidase, subunit VIIa 25
    cytochrome c oxidase subunit VIIa 21
    81.3(n)1
    81.71(a)1
      9 (43.82 cM)5
    128661  NM_009945.31  NP_034075.21 
     797552415 
    chicken
    (Gallus gallus)
    Aves COX7A21 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 74.3(n)
    69.88(a)
      772260  NM_001198782.1  NP_001185711.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.75702 Xenopus laevis, clone IMAGE5542050, mRNA 75.36(n)    BC045069.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cox7a21 cytochrome c oxidase, subunit VIIa 2 58.63(n)
    54.22(a)
      554103  NM_001032728.1  NP_001027900.1 


    ENSEMBL Gene Tree for COX7A2 (if available)
    TreeFam Gene Tree for COX7A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COX7A2 gene
    COX7A12  COX7A2L2  
    18/51 SIMAP similar genes for COX7A2 using alignment to 8 protein entries:     CX7A2_HUMAN (see all proteins) (see all similar genes):
    DRG2    IFT122    MTA3    NUSAP1    ZNF738    CCPG1
    IPO7    KLHDC1    NSRP1    SCIMP    COX7A2P2    FAM3A
    WDR6    C19orf47    NSD1    ZNF23    ZNF480    LGALS3

    COX7A2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for COX7A2
    PGOHUM00000250108 PGOHUM00000246005


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/195 SNPs in COX7A2 are shown (see all 195)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0123194
    ----see VAR_0123192 E D mis40--------
    rs1161112471,2
    C,F--75947009(+) ATAGCT/GGGGGA 2 -- ds50011Minor allele frequency- G:0.10WA 118
    rs1163630031,2
    C,F--75947027(+) AACTGT/CCCTGC 2 -- ds50013Minor allele frequency- C:0.06WA NA EA 358
    rs1116379091,2
    C,F--75947129(+) TAAAGC/TCTAAT 2 -- ds50011Minor allele frequency- T:0.50NA 2
    rs558327041,2
    C--75947186(+) CTGAG-/AAAAAA 2 -- ds50011Minor allele frequency- A:0.00NA 2
    rs2020754421,2
    C--75947186(+) CTGAG-/AAAAAA
            
    AAAAA
    2 -- ds50010--------
    rs756967231,2
    C,F--75947301(+) AGCAAT/CATGCA 2 -- ds50011Minor allele frequency- C:0.09WA 118
    rs1399293771,2
    C--75947353(+) GCTGTC/TAGAAG 2 -- ds50010--------
    rs1134300681,2
    C,F--75947487(+) AAGTGG/ATAAAA 2 -- ut31 nc-transcript-variant3Minor allele frequency- A:0.43CSA 7
    rs10600031,2
    H--75947585(-) GTAATC/TTGATA 2 -- ut31 nc-transcript-variant5Minor allele frequency- T:0.00NS EA NA 406

    HapMap Linkage Disequilibrium report for COX7A2 (75947391 - 75960039 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for COX7A2: --

    Human Gene Mutation Database (HGMD): COX7A2
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 123996    OMIM disorders: --

    9 diseases for COX7A2:    About MalaCards
    barrett's adenocarcinoma    hepatitis    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    huntington's disease    parkinson's disease    alzheimer's disease    adenocarcinoma
    prostatitis


    COX7A2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): COX7A2
    Human Genome Epidemiology (HuGE) Navigator: COX7A2 (2 documents)

    Export disorders for COX7A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COX7A2 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with COX7A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and sequence of the human cytochrome c oxidase subunit VIIaL gene. (PubMed id 11004498)1, 2, 9 Huettemann M....Kadenbach B. (2000)
    2. Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase. (PubMed id 1327965)1, 3, 9 Arnaudo E.... Schon E.A. (1992)
    3. Iterative orthology prediction uncovers new mitochond rial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. (PubMed id 22356826)1, 2 Szklarczyk R....Huynen M.A. (2012)
    4. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    5. Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (2008)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    8. Chromosomal localization of the human liver form cytochrome c oxidase subunit VIIa gene. (PubMed id 9202412)1, 3 Merante F....Robinson B.H. (1997)
    9. Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both 'heart-type' and 'liver-type' isoforms of subunit VIIa in human heart. (PubMed id 1309697)1, 2 van Kuilenburg A.B.P....Muijsers A.O. (1992)
    10. Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase. (PubMed id 2550906)1, 2 Fabrizi G.M....Schon E.A. (1989)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1347 HGNC: 2288 AceView: COX7A2 Ensembl:ENSG00000112695 euGenes: HUgn1347
    ECgene: COX7A2 Kegg: 1347 H-InvDB: COX7A2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COX7A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COX7A2 gene:
    Search GeneIP for patents involving COX7A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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