Aliases for COX7A1 Gene
External Ids for COX7A1 Gene
Previous HGNC Symbols for COX7A1 Gene
Previous GeneCards Identifiers for COX7A1 Gene
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008]
GeneCards Summary for COX7A1 Gene
COX7A1 (Cytochrome C Oxidase Subunit 7A1) is a Protein Coding gene. Among its related pathways are Alzheimer's disease and Cardiac muscle contraction. GO annotations related to this gene include electron carrier activity and cytochrome-c oxidase activity. An important paralog of this gene is COX7A2.
UniProtKB/Swiss-Prot for COX7A1 Gene
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.