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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX7A1 Gene

protein-coding   GIFtS: 54
GCID: GC19M036641

cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)


(Previous symbol: COX7A)
 Explore 2 diseases affiliated with
COX7A1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for COX7A1    

Aliases
for COX7A1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cytochrome C Oxidase Subunit VIIa Polypeptide 1 (Muscle)1 2     Cytochrome C Oxidase Subunit VIIa-M2 3
COX7AH1 2 3     Cytochrome C Oxidase Subunit VIIa-Muscle2 3
COX7A1 2     COX7AM2 5
Cytochrome C Oxidase Subunit VIIa-H2 3     Cytochrome C Oxidase Subunit 7A1, Mitochondrial2
Cytochrome C Oxidase Subunit VIIa-Heart2 3     Cytochrome C Oxidase Subunit VIIa Heart/Muscle Isoform2

External Ids:    HGNC: 22871   Entrez Gene: 13462   Ensembl: ENSG000001612817   OMIM: 1239955   UniProtKB: P243103   

Export aliases for COX7A1 gene to outside databases

Previous GC identifers: GC19M037280 GC19M037090 GC19M041317 GC19M041333 GC19M033149


Summaries
for COX7A1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for COX7A1:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron
transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic
subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The
mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the
regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and
the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and
nonmuscle tissues, and are encoded by different genes. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CX7A1_HUMAN, P24310
Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in
mitochondrial electron transport

Gene Wiki entry for COX7A1


Genomic Views
for COX7A1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX7A1 gene promoter:
         NF-1   AP-1   AML1a   CUTL1   YY1   RORalpha1   MZF-1   POU2F1   POU2F1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: COX7A1 promoter sequence
   Search SABiosciences Chromatin IP Primers for COX7A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX7A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.1   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.1

COX7A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX7A1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M036641:  view genomic region     (about GC identifiers)

Start:
 36,641,824 bp from pter      End:
 36,643,771 bp from pter
Size:
 1,948 bases      Orientation:
 minus strand

Proteins
for COX7A1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CX7A1_HUMAN, P24310 (See protein sequence)
Recommended Name: Cytochrome c oxidase subunit 7A1, mitochondrial precursor  
Size: 79 amino acids; 9118 Da
Subcellular location: Mitochondrion inner membrane

Explore the universe of human proteins at neXtProt for COX7A1: NX_P24310

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P24310

    • COX7A1 Protein expression data from MOPED and PaxDb:    About this image 
    COX7A1 Protein Expression
    REFSEQ proteins: NP_001855.1  
    ENSEMBL proteins: 
     ENSP00000292907   ENSP00000468063  

    Human Recombinant Protein Products for COX7A1: 
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    Novus Biologicals COX7A1 Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for COX7A1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion TAS9344674
    GO:0005746mitochondrial respiratory chain IEA--
    GO:0016021integral to membrane IEA--

    COX7A1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for COX7A1

    Protein Domains /
    Families
    for COX7A1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    COX7A1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR003177 Cyt_c_oxidase_su7a

    Graphical View of Domain Structure for InterPro Entry P24310

    ProtoNet protein and cluster: P24310

    1 Blocks protein family: IPB003177 Cytochrome c oxidase

    UniProtKB/Swiss-Prot: CX7A1_HUMAN, P24310
    Similarity: Belongs to the cytochrome c oxidase VIIa family


    Function
    for COX7A1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CX7A1_HUMAN, P24310
    Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in
    mitochondrial electron transport

         Genatlas biochemistry entry for COX7A1:
    cytochrome c oxidase,subunit VIIa,polypeptide 1,heart muscle,with a nuclear respiratory factor 2 (NRF-2) binding
    site,component of the complex IV,terminal enzyme complex for electron transfert,oxidative phosphorylation
    (OXPHOS),inner mitochondrial membrane

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity IEA--
    GO:0009055electron carrier activity IEA--
         
    COX7A1 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Cox7a1):
     cardiovascular system  cellular  mortality/aging  muscle 

    COX7A1 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Cox7a1tm1Hutt for COX7A1
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for COX7A1 

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of COX7A1 
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for COX7A1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    		Electron Transport Chain0.76
    		Alzheimer's disease0.43
    		Oxidative phosphorylation0.63
    		Huntington's disease0.40
    		Parkinson's disease0.61
    2AMPK Enzyme Complex Pathway
    		AMPK Enzyme Complex Pathway1.00
    3Cardiac muscle contraction
    		Cardiac muscle contraction1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for COX7A1
        AMPK Enzyme Complex Pathway

    1 BioSystems Pathway for COX7A1 
        Electron Transport Chain


    5         Kegg Pathways  (Kegg details for COX7A1):
        Oxidative phosphorylation
    Cardiac muscle contraction
    Alzheimer's disease
    Parkinson's disease
    Huntington's disease


    COX7A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX7A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/17 Interacting proteins for COX7A1 (ENSP000002929074) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COX5BENSP000002584244STRING: ENSP00000258424
    UQCRHENSP000003095654STRING: ENSP00000309565
    COX5AENSP000003177804STRING: ENSP00000317780
    CYC1ENSP000003171594STRING: ENSP00000317159
    ENSG00000267059ENSP000002629464STRING: ENSP00000262946
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006091generation of precursor metabolites and energy TAS9344674

    COX7A1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for COX7A1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COX7A1

    2 HMDB Compounds for COX7A1    About this table
    CompoundSynonyms CAS #PubMed Ids
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    2 DrugBank Compounds for COX7A1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Cholic Acid-- 81-25-4target--10592235
    N-Formylmethionine-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about COX7A1 / CX7A1 

    Transcripts
    for COX7A1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for COX7A1 gene: 
    NM_001864.2  

    Unigene Cluster for COX7A1:

    Cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
    Hs.421621  [show with all ESTs]
    Unigene Representative Sequence: CD299556
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000437291 ENST00000481297 ENST00000292907(uc002odm.1) ENST00000589154


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    Inhib. RNA
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    OriGene siRNA: COX7A1
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    Sirion Biotech Custom design and validation of potent shRNA sequences against COX7A1 
    Clone
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    Primer
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    Additional cDNA sequence: 

    AK312091.1 BC002757.2 BT006924.1 CR542120.1 HE647857.1 M83186.1 

    4 DOTS entries:

    DT.75155515  DT.100777018  DT.95306680  DT.92420932 

    24/236 AceView cDNA sequences (see all 236):

    F30447 F27279 F25786 F36309 BM726594 CR542120 AA192556 F37144 
    F30024 BQ639430 AA526858 F26035 F24634 AI811022 F27421 F24459 
    F29216 F30042 C05621 CD243077 F34960 F31248 AJ573270 CK826118 

    GeneLoc Exon Structure


    Expression
    for COX7A1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COX7A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    COX7A1 Expression
    About this image

    COX7A1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PancreasDorsal Pancreatic BudImmature Beta Progenitor CellsPancreas
    PancreasVentral Pancreatic BudImmature Beta Progenitor CellsPancreas
    AdiposeBody Subcutaneous White AdiposeAdipose
    AdiposeInterscapular Brown Adipose DepotAdipose
    AdiposeThoracic Perivascular AdiposeAdipose
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Fetal cardiomyocytes (20 weeks) (Primary Cell)Heart, Myocardium
    Definitive endoderm-like cells (A scalable, suspensi...)

    See COX7A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COX7A1

    SOURCE GeneReport for Unigene cluster: Hs.421621
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX7A1

    Orthologs
    for COX7A1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of human and mouse.

    Orthologs for COX7A1 gene from 1/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cox7a11 , 5 cytochrome c oxidase, subunit VIIa 15
    cytochrome c oxidase subunit VIIa 11    		 77.06(n)1
    72.73(a)1    		   7 (17.31 cM)5
    128651  NM_009944.31  NP_034074.11 
     301841715 


    ENSEMBL Gene Tree for COX7A1 (if available)
    TreeFam Gene Tree for COX7A1 (if available) 

    Paralogs
    for COX7A1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COX7A1 gene
    COX7A2L2  COX7A22  
    3 SIMAP similar genes for COX7A1 using alignment to 4 protein entries:     CX7A1_HUMAN (see all proteins):
    COX7A2    COX7A2P2    COX7A2L

    COX7A1 for paralogs           About GeneDecksing



    Genomic Variants
    for COX7A1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/80 NCBI SNPs in COX7A1 are shown (see all 80)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs178854881,2
    		C,F,H--36641835(+) CCAGCG/ATTTAT 1 -- ut31 ese34Minor allele frequency- A:0.01NS NA 344
    rs18033701,2
    		C,F--36641932(-) GGCACT/CGTCTA 2 /T syn12Minor allele frequency- C:0.00NA EU 5875
    rs1125979681,2
    		C--36641938(+) GTGCCA/G/TAGAAA 1 -- spa11CSA 1
    rs1119607721,2
    		C--36641939(+) TGCCTA/C/TGAAAG 1 -- int11CSA 1
    rs2006889641,2
    		--36641977(+) TAATCC/TCCTCC 1 -- int10--------
    rs1511946211,2
    		--36641996(+) CCCAGC/GCTTTT 1 -- int10--------
    rs1403397821,2
    		--36642036(+) TGGACC/TCCAGC 1 -- int10--------
    rs361086271,2
    		C,F--36642127(+) GCTTTG/CTCCCC 1 -- int12Minor allele frequency- C:0.50NA 4
    rs776551781,2
    		--36642179(+) CGTCCT/CGGGAC 1 -- int11Minor allele frequency- C:0.01EA 120
    rs20086831,2
    		C,H--36642310(+) ACCTCC/TTACTC 1 -- int115Minor allele frequency- T:0.03MN NA WA CSA EA 565

    HapMap Linkage Disequilibrium report for COX7A1 (36641824 - 36643771 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for COX7A1: --
    Human Gene Mutation Database (HGMD): COX7A1

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COX7A1
    DNA2.0 Custom Variant and Variant Library Synthesis for COX7A1

    Disorders / Diseases
    for COX7A1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    COX7A1 for disorders           About GeneDecksing

    OMIM gene information: 123995    OMIM disorders: --

    2 diseases for COX7A1:    About MalaCards
    huntington's disease    parkinson's disease

    Human Genome Epidemiology (HuGE) Navigator: COX7A1 (5 documents)

    Export disorders for COX7A1 gene to outside databases

    Publications
    for COX7A1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COX7A1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with COX7A1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase. (PubMed id 1327965)1, 2, 3, 9 Arnaudo E.... Schon E.A. (1992)
    2. Genomic organization and promoter regulation of human cytochrome c oxidase subunit VII heart/muscle isoform (COX7AH). (PubMed id 11997101)1, 2, 9 Yu M.... Grossman L.I. (2002)
    3. Molecular evolution of the COX7A gene family in primates. (PubMed id 10335655)1, 2, 9 Schmidt T.R.... Grossman L.I. (1999)
    4. Genomic sequence and organization of the human gene for cytochrome c oxidase subunit (COX7A1) VIIa-M. (PubMed id 9344674)1, 2, 9 Wolz W.... Mueller C.R. (1997)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    7. Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both 'heart-type' and 'liver-type' isoforms of subunit VIIa in human heart. (PubMed id 1309697)1, 2 van Kuilenburg A.B.P....Muijsers A.O. (1992)
    8. Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase. (PubMed id 2550906)1, 3 Fabrizi G.M....Schon E.A. (1989)
    9. HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
    10. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)

    External Searches for COX7A1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing COX7A1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1346 HGNC: 2287 AceView: COX7A1 Ensembl:ENSG00000161281 euGenes: HUgn1346
    ECgene: COX7A1 Kegg: 1346 H-InvDB: COX7A1

    Other Databases showing COX7A1 gene

    (According to HUGE)
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    Specialized Databases showing COX7A1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COX7A1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for COX7A1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for COX7A1 gene:
    Search GeneIP for patents involving COX7A1

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