COX6B1 Gene
protein-coding GIFtS: 59
GCID: GC19P036140
|
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)(Previous names: cytochrome c oxidase subunit Vib, cytochrome c oxidase...)
(Previous symbol: COX6B)
| |
Aliases
for COX6B1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous)1 2 | | Cytochrome C Oxidase Subunit Vib1 | | COX6B1 2 3 | | COXVIb12 | | COXG1 2 | | Cytochrome C Oxidase Subunit 6B12 | | COX VIb-12 3 | | Cytochrome C Oxidase Subunit VIb Isoform 13 |
Export aliases for COX6B1 gene to outside databasesPrevious GC identifers: GC19P040831 GC19P032644 |
Summaries
for COX6B1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for COX6B1:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transferfrom reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded bymitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunitsfunction in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of thecomplex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantileencephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and22q13.1-13.2, respectively. (provided by RefSeq, Jan 2010)
UniProtKB/Swiss-Prot: CX6B1_HUMAN, P14854Function: Connects the two COX monomers into the physiological dimeric form (By similarity)
Gene Wiki entry for COX6B1
|
Genomic Views
for COX6B1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the COX6B1 gene promoter:
E2F-4 E2F-3a E2F-5 HTF RelA E2F-2 GATA-2 c-Ets-1 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for COX6B1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX6B1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q13.1COX6B1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P036140: view genomic region
(about GC identifiers)
Start:
|
36,139,125 bp from pter |
End:
|
36,149,763 bp from pter |
Size:
|
10,639 bases |
Orientation:
|
plus strand |
|
Proteins
for COX6B1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CX6B1_HUMAN, P14854 (See
protein sequence)Recommended Name: Cytochrome c oxidase subunit 6B1 Size: 86 amino acids; 10192 Da
Subcellular location: Mitochondrion intermembrane space (By similarity)
Secondary accessions: B2R5C9 Q6IBL4Explore the universe of human proteins at neXtProt for COX6B1: NX_P14854
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P14854
COX6B1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001854.1
ENSEMBL proteins: ENSP00000246554 ENSP00000466818 ENSP00000376037 ENSP00000467776 Reactome Protein details: P14854
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IDA | -- | | GO:0005743 | mitochondrial inner membrane |
TAS | -- | | GO:0005758 | mitochondrial intermembrane space |
IEA | -- |
COX6B1 for ontologies About GeneDecksing
COX6B1 Antibody Products:
Assay Products for COX6B1: |
Protein
Domains /
Families
for COX6B1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
COX6B1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P14854ProtoNet protein and cluster: P14854 1 Blocks protein family: IPB003213 Cytochrome oxidase c
UniProtKB/Swiss-Prot: CX6B1_HUMAN, P14854Similarity: Belongs to the cytochrome c oxidase subunit 6B family |
Function
for COX6B1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CX6B1_HUMAN, P14854Function: Connects the two COX monomers into the physiological dimeric form (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: COX6B1 (NM_001863) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COX6B1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX6B1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004129 | cytochrome-c oxidase activity |
NAS | 2172092 |
COX6B1 for ontologies About GeneDecksing
|
Pathways & Interactions
for COX6B1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | | | 3 | Cardiac muscle contraction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for COX6B1
4 
Reactome Pathways for COX6B1
5/6 
Kegg Pathways (Kegg details for COX6B1) (see all 6):
COX6B1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX6B1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/30 Interacting proteins for COX6B1 (P148543 ENSP000002465544) via UniProtKB, MINT, STRING, and/or I2D (see all 30)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0022904 | respiratory electron transport chain |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- | | GO:0055114 | oxidation-reduction process |
NAS | -- |
COX6B1 for ontologies About GeneDecksing
|
Drugs & Compounds
for COX6B1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for COX6B1
2 HMDB Compounds for COX6B1 About this table
2 DrugBank Compounds for COX6B1 About this table
Search CenterWatch for drugs/clinical trials and news about COX6B1 / CX6B1
|
Transcripts
for COX6B1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for COX6B1 gene: NM_001863.4 Unigene Cluster for COX6B1: Cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) Hs.431668 [show with all ESTs]Unigene Representative Sequence: CD5179594 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000246554(uc002oav.3) ENST00000592141 ENST00000392201 ENST00000590618
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: COX6B1 (NM_001863) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COX6B1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX6B1 |
Additional cDNA sequence: AK312140.1 BC001015.2 BC002478.2 BT006945.1 CR456789.1 CR542137.1 X13923.1 X54473.1 17 DOTS entries: DT.100693282 DT.87018180 DT.100826502 DT.100826505 DT.121410468 DT.121410479 DT.100044739 DT.99986089 DT.100826506 DT.91769100 DT.95259097 DT.121410464 DT.121410465 DT.92373372 DT.95312469 DT.121124434 DT.121124435 24/551 AceView cDNA sequences (see all 551): W73200 AA825249 AA903983 BF056151 AI354663 AA872391 AI500212 AI086974 BU730166 AI203949 BG574973 W76623 W73015 AJ712039 BG165187 AA010262 AI306607 BX106670 AI567551 AI167254 BE019228 AA706321 AA047248 AA758037
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for COX6B1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | - | | | |
ECgene alternative splicing isoforms for COX6B1
|
Expression
for COX6B1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| COX6B1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTTACCTGC
About this image
See COX6B1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COX6B1
SOURCE GeneReport for Unigene cluster: Hs.431668
SABiosciences Expression via Pathway-Focused PCR Arrays including COX6B1: | Mitochondrial Energy Metabolism in human mouse rat | | Molecular Toxicology PathwayFinder 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COX6B1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COX6B1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX6B1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX6B1 |
Orthologs
for COX6B1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for COX6B1 gene from 7/30 species (see all 30) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.347242 |
Xenopus laevis transcribed sequence with weak similarity more |
69.9(n) |
|
BJ637694.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufa92g052 |
Transcribed sequence with moderate similarity to protein more |
73(n) |
|
BI671464.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG142351 |
CG14235 |
64.79(n)
61.97(a) |
|
32989 NM_167678.2 NP_728294.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y71H2AM.56 |
Protein Y71H2AM.5 |
28(a) |
1 → many |
III(2786109-2786851) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
COX12(YLR038C)4
COX121 |
Subunit VIb of cytochrome c oxidase, which is the terminal more4
Cox12p1 |
53.81(n)1
48.57(a)1 |
|
12(225172-224921)4
8507271, 4 NP_013139.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
COX6B1 |
cytochrome C oxidase 6B |
53.25(n)
50(a) |
|
838851 NM_102094.3 NP_173661.1 |
rice
(Oryza sativa) |
Liliopsida |
Os03g03904001 |
hypothetical protein |
52.99(n)
52.56(a) |
|
4333018 NM_001056810.1 NP_001050275.1 |
ENSEMBL Gene Tree for COX6B1 (if available)
TreeFam Gene Tree for COX6B1 (if available) |
Paralogs
for COX6B1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for COX6B1 gene
- COX6B22
1 SIMAP similar gene for COX6B1 using alignment to 2 protein entries: CX6B1_HUMAN (see all proteins):COX6B2
COX6B1 for paralogs About GeneDecksing
5/7 Pseudogenes.org Pseudogenes for COX6B1 (see all 7)
PGOHUM00000237426 PGOHUM00000244751 PGOHUM00000246592 PGOHUM00000245807 PGOHUM00000233640
|
Genomic Variants
for COX6B1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for COX6B1 (36139125 - 36149763 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for COX6B1: --
Human Gene Mutation Database (HGMD): COX6B1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COX6B1 |
|
Disorders
/ Diseases
for COX6B1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
COX6B1 for disorders About GeneDecksing
OMIM gene information: 124089
OMIM disorders: 220110
UniProtKB/Swiss-Prot: CX6B1_HUMAN, P14854
Defects in COX6B1 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known ascytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinicalmanifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness,excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patientsmanifest Leigh syndrome
6  diseases for COX6B1: About MalaCardsencephalomyopathy huntington's disease hypotonia parkinson's disease
breast cancer carcinoma
Human Genome Epidemiology (HuGE) Navigator: COX6B1 (1 document)
Export disorders for COX6B1 gene to outside databases
|
Publications
for COX6B1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for COX6B1 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with COX6B1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human cytochrome c oxidase subunit VIb: characterization and mapping of a multigene family. (PubMed id 1651883)1, 2, 9 Carrero-Valenzuela R.D.... Forte M.A. (1991)
- Nucleotide sequence of the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking regions. (PubMed id 1647217)1, 2, 9 Taanman J.-W....de Vries H. (1991)
- Severe infantile encephalomyopathy caused by a mutation in COX6B1, a nucleus-encoded subunit of cytochrome c oxidase. (PubMed id 18499082)1, 2 Massa V....Zeviani M. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Assignment of the gene coding for human cytochrome c oxidase subunit VIb to chromosome 19, band q13.1, by fluorescence in situ hybridisation. (PubMed id 1650756)1, 3 Taanman J.W....Buys C.H. (1991)
- Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues. (PubMed id 2172092)1, 2 Taanman J.-W.... Agsteribbe E. (1990)
- Nucleotide sequence of cDNA encoding subunit VIb of human cytochrome c oxidase. (PubMed id 2537962)1, 2 Taanman J.-W....Agsteribbe E. (1989)
- HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for COX6B1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing COX6B1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing COX6B1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing COX6B1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for COX6B1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for COX6B1 gene:
Search GeneIP for patents involving COX6B1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for COX6B1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for COX6B1 | | OriGene shRNA RFP for COX6B1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COX6B1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COX6B1 | | | OriGene Protein Over-expression Lysate for COX6B1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for COX6B1 | | OriGene 3'-UTR Clone for COX6B1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX6B1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for COX6B1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for COX6B1 | | OriGene Custom Protein Services for COX6B1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COX6B1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COX6B1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX6B1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COX6B1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX6B1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX6B1 |
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| | | | Search Tocris compounds for COX6B1 |
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 | | | COX6B1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibody for COX6B1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX6B1 |
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