COX4I1 Gene
protein-coding GIFtS: 61
GCID: GC16P085833
|
|
cytochrome c oxidase subunit IV isoform 1(Previous name: cytochrome c oxidase subunit IV ) (Previous symbol: COX4)
| |
Aliases for COX4I1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Cytochrome C Oxidase Subunit IV Isoform 11 2 3 | | COX IV-12 3 | | COX41 2 3 5 | | Cytochrome C Oxidase Subunit IV1 | | COX4-11 2 | | COXIV2 | | Cytochrome C Oxidase Polypeptide IV2 3 | | Cytochrome C Oxidase Subunit 4 Isoform 1, Mitochondrial2 |
Export aliases for COX4I1 gene to outside databasesPrevious GC identifers: GC16P077058 GC16P086866 GC16P085573 GC16P085614 GC16P084390 GC16P071574 |
Summaries for COX4I1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for COX4I1: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzymecomplex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a protonelectrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- andnuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumpingactivities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation andassembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrialrespiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: COX41_HUMAN, P13073Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase inmitochondrial electron transport Gene Wiki entry for COX4I1
|
Genomic Views for COX4I1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the COX4I1 gene promoter: MAZR AML1a HTF NCX/Ncx YY1 Max PPAR-gamma1 PPAR-gamma2 c-Myc ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for COX4I1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX4I1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.1 Ensembl cytogenetic band: 16q24.1 HGNC cytogenetic band: 16q24.1COX4I1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P085833: view genomic region
(about GC identifiers)
Start:
|
85,832,239 bp from pter |
End:
|
85,840,650 bp from pter |
Size:
|
8,412 bases |
Orientation:
|
plus strand |
|
Proteins for COX4I1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: COX41_HUMAN, P13073 (See
protein sequence)Recommended Name: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor Size: 169 amino acids; 19577 Da
Subcellular location: Mitochondrion inner membrane
Secondary accessions: B2R4J2 D3DUM7 Q6P666Explore the universe of human proteins at neXtProt for COX4I1: NX_P13073
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P13073 COX4I1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001852.1 ENSEMBL proteins: ENSP00000454869 ENSP00000455437 ENSP00000455030 ENSP00000253452 ENSP00000457513 ENSP00000457015 ENSP00000455301 ENSP00000456452 ENSP00000454714 Reactome Protein details: P13073 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
COX4I1 for ontologies About GeneDecksing
COX4I1 Antibody Products: Assay Products for COX4I1: |
Protein
Domains / Families for COX4I1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
COX4I1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P13073ProtoNet protein and cluster: P13073 1 Blocks protein family: IPB004203 Cytochrome c oxidase subunit IV
UniProtKB/Swiss-Prot: COX41_HUMAN, P13073Similarity: Belongs to the cytochrome c oxidase IV family |
Function for COX4I1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: COX41_HUMAN, P13073Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase inmitochondrial electron transport
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: COX4I1 (NM_001861) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COX4I1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX4I1  |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004129 | cytochrome-c oxidase activity |
IEA | -- |
COX4I1 for ontologies About GeneDecksing
Animal Models: 1 MGI phenotypic allele for Cox4i1 (no phenotypes)
COX4I1 for phenotypes About GeneDecksing
|
Pathways & Interactions for COX4I1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | | | 3 | Glucose / Energy Metabolism | | | 4 | Cytoskeletal Signaling | | | 5 | Apoptosis and Autophagy | |
Pathway sources See GeneCards unified pathways Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for COX4I1 3
Cell Signaling Technology (CST) Pathways for COX4I1 1 BioSystems Pathway for COX4I1 
4
Reactome Pathways for COX4I1
5/6
Kegg Pathways (Kegg details for COX4I1) (see all 6):
COX4I1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX4I1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/259 Interacting proteins for COX4I1 (P130731, 2, 3 ENSP000002534524) via UniProtKB, MINT, STRING, and/or I2D (see all 259)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006091 | generation of precursor metabolites and energy |
TAS | 2157630 | | GO:0007584 | response to nutrient |
IEA | -- | | GO:0022904 | respiratory electron transport chain |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
COX4I1 for ontologies About GeneDecksing
|
Drugs & Compounds for COX4I1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
COX4I1 for compounds About GeneDecksing
Browse Tocris compounds for COX4I1
2 HMDB Compounds for COX4I1 About this table
2 DrugBank Compounds for COX4I1 About this table
3 Novoseek chemical compound relationships for COX4I1 gene About this table
Search CenterWatch for drugs/clinical trials and news about COX4I1 / COX41 
|
Transcripts for COX4I1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for COX4I1 gene: NM_001861.3 Unigene Cluster for COX4I1: Cytochrome c oxidase subunit IV isoform 1 Hs.433419 [show with all ESTs]Unigene Representative Sequence: BF31614818 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000565078 ENST00000570123 ENST00000568339(uc002fje.3 uc002fjf.3) ENST00000566115 ENST00000567241 ENST00000568794 ENST00000253452 ENST00000562336 ENST00000563774 ENST00000567266 ENST00000561569 ENST00000566405 ENST00000564544 ENST00000566617 ENST00000564648 ENST00000564903 ENST00000569997 ENST00000562929
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: COX4I1 (NM_001861) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COX4I1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX4I1  |
Additional cDNA sequence: AK311847.1 BC008704.1 BC021236.2 BC062437.1 BT019825.1 M21575.1 M34600.1 U90915.1 X54802.1 24/28 DOTS entries (see all 28): DT.100673712 DT.420414 DT.100039062 DT.92406997 DT.455163 DT.100862378 DT.120687900 DT.95363546 DT.95091958 DT.87014109 DT.95178636 DT.91767775 DT.120687925 DT.85101409 DT.95091949 DT.120687941 DT.95092027 DT.100862383 DT.101968064 DT.120687917 DT.91767776 DT.91863124 DT.91995104 DT.95091954 24/982 AceView cDNA sequences (see all 982): BQ271136 AA513023 BQ130653 AW327609 CA841904 BM663168 BM854697 BM700493 CR592979 CD613066 H06316 T61019 AA425535 BG034212 F11128 BU728209 BI335897 CR590992 CR591678 AI983416 CA774659 BQ026383 BM767046 BM773149 GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for COX4I1 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   |
ECgene alternative splicing isoforms for COX4I1
|
Expression for COX4I1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| COX4I1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCTATTTACT
About this image See COX4I1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for COX4I1
SOURCE GeneReport for Unigene cluster: Hs.433419 UniProtKB/Swiss-Prot: COX41_HUMAN, P13073Tissue specificity: Ubiquitous SABiosciences Expression via Pathway-Focused PCR Array including COX4I1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COX4I1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COX4I1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX4I1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX4I1 |
Orthologs for COX4I1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for COX4I1 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
COX4I11 |
cytochrome c oxidase subunit IV isoform 1 |
69.23(n) 69.82(a) |
  |
415826 NM_001030577.1 NP_001025748.1 |
lizard (Anolis carolinensis) |
Reptilia |
COX4I16 |
-- |
71(a) |
1 ↔ 1 |
GL343454.1(486719-490361) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.247622 |
Xenopus laevis transcribed sequence with weak similarity more |
71.23(n) |
  |
48052114 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.281652 |
Danio rerio cytochrome c oxidase subunit IV isoform more |
72.73(n) |
  |
AY391417.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG103961 |
CG10396 |
46.11(n) 35.33(a) |
  |
35491 NM_136324.3 NP_610168.1 |
worm (Caenorhabditis elegans) |
Secernentea |
W09C5.86 |
Protein W09C5.8 |
23(a) |
1 → many |
I(13658159-13659118) |
ENSEMBL Gene Tree for COX4I1 (if available) TreeFam Gene Tree for COX4I1 (if available)  |
Paralogs for COX4I1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for COX4I1 gene
- COX4I22
2 SIMAP similar genes for COX4I1 using alignment to 7 protein entries: COX41_HUMAN (see all proteins):C4orf26 COX4I2
COX4I1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for COX4I1 PGOHUM00000262205 PGOHUM00000247822
|
Genomic Variants for COX4I1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for COX4I1 (85832239 - 85840650 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for COX4I1: -- Human Gene Mutation Database (HGMD): COX4I1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COX4I1 |
|
Disorders
/ Diseases for COX4I1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
COX4I1 for disorders About GeneDecksing
OMIM gene information: 123864
OMIM disorders: --
15 diseases for COX4I1: About MalaCardsceroid lipofuscinosis calvarial hyperostosis neuronal ceroid-lipofuscinosis exocrine pancreatic insufficiency hyperostosis batten disease huntington's disease parkinson's disease alzheimer's disease prostate cancer pancreatitis anemia obesity prostatitis neuronitis Human Genome Epidemiology (HuGE) Navigator: COX4I1 (1 document) Export disorders for COX4I1 gene to outside databases
|
Publications for COX4I1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for COX4I1 gene, integrated from 9 sources (see all 82): (articles sorted by number of sources associating them with COX4I1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV. (PubMed id 2157630)1, 2, 3, 9 Lomax M.I.... Grossman L.I. (1990)
- Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase. (PubMed id 2444497)1, 2, 3 Zeviani M.... Schon E.A. (1987)
- The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4. (PubMed id 10337626)1, 2, 9 Bachman N.J.... Lomax M.I. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Subunit IV of human cytochrome c oxidase, polymorphism and a putative isoform. (PubMed id 1311608)1, 2 van Kuilenburg A.B.P.... Muijsers A.O. (1992)
- Rapid evolution of the human gene for cytochrome c oxidase subunit IV. (PubMed id 1319058)1, 9 Lomax M.I....Grossman L.I. (1992)
- Cytochrome c oxidase and nitric oxide in action: molec ular mechanisms and pathophysiological implications. (PubMed id 21939634)1 Sarti P....Arese M. (2012)
- The mechanism for proton pumping in cytochrome c oxida se from an electrostatic and quantum chemical perspective. (PubMed id 21978537)1 Blomberg M.R. and Siegbahn P.E. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- HIV-1 Tat protein directly induces mitochondrial membr ane permeabilization and inactivates cytochrome c oxidase. (PubMed id 22419111)1 Lecoeur H....Jacotot E. (2012)
|
External Searches for COX4I1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing COX4I1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing COX4I1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing COX4I1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for COX4I1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for COX4I1 gene: Search GeneIP for patents involving COX4I1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for COX4I1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for COX4I1 | | OriGene shRNA RFP for COX4I1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COX4I1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COX4I1 | | OriGene Protein Over-expression Lysate for COX4I1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for COX4I1 | | OriGene 3'-UTR Clone for COX4I1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COX4I1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for COX4I1 | | OriGene Custom Protein Services for COX4I1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COX4I1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COX4I1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX4I1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COX4I1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX4I1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COX4I1 |
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| Antibodies & Assays for COX4I1  |
| | | Search Tocris compounds for COX4I1 |
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 | | COX4I1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | ThermoFisher Antibody for COX4I1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX4I1 |
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