Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



COX20 Gene

protein-coding   GIFtS: 43
GCID: GC01P245000

COX20 Cytochrome C Oxidase Assembly Factor

(Previous names: family with sequence similarity 36, member A, COX20 Cox2...)
(Previous symbol: FAM36A)
  See COX20-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
COX20 Cytochrome C Oxidase Assembly Factor1 2     COX20 Cox2 Chaperone Homolog2
FAM36A1 2 3 5     Cytochrome C Oxidase Protein 20 Homolog2
Family With Sequence Similarity 36, Member A1 2     Protein FAM36A2
COX20 Cox2 Chaperone Homolog (S. Cerevisiae)1     

External Ids:    HGNC: 269701   Entrez Gene: 1162282   Ensembl: ENSG000002036677   OMIM: 6146985   UniProtKB: Q5RI153   
ORGUL members:         

Export aliases for COX20 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for COX20 Gene:
COX20 (COX20 cytochrome C oxidase assembly factor) is a protein-coding gene. Diseases associated with COX20 include cytochrome-c oxidase deficiency disease.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_167186.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for COX20
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX20 promoter sequence
   Search Chromatin IP Primers for COX20

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

COX20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX20 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P245000:  view genomic region     (about GC identifiers)

Start:
244,998,624 bp from pter      End:
245,008,359 bp from pter
Size:
9,736 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: COX20_HUMAN, Q5RI15 (See protein sequence)
Recommended Name: Cytochrome c oxidase protein 20 homolog  
Size: 118 amino acids; 13291 Da
Secondary accessions: Q8WV86
Alternative splicing: 2 isoforms:  Q5RI15-1   Q5RI15-2   (Gene prediction confirmed by EST data)

Explore the universe of human proteins at neXtProt for COX20: NX_Q5RI15

Explore proteomics data for COX20 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys98
  • Modification sites at PhosphoSitePlus

  • See COX20 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_932342.1  
    ENSEMBL proteins: 
     ENSP00000406327   ENSP00000355486  

    COX20 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for COX20
    OriGene Protein Over-expression Lysate for COX20
    OriGene MassSpec for COX20
    OriGene Custom Protein Services for COX20
    GenScript Custom Purified and Recombinant Proteins Services for COX20
    Novus Biologicals COX20 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for COX20 

    COX20 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for COX20
    Novus Biologicals COX20 Antibodies
    Search for Antibodies for COX20 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for COX20
    LSBio Antibodies in human, mouse, rat for COX20

    COX20 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for COX20
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for COX20
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for COX20 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    2 InterPro protein domains:
     IPR022533 Cox20/FAM36A
     IPR023242 FAM36A

    Graphical View of Domain Structure for InterPro Entry Q5RI15

    ProtoNet protein and cluster: Q5RI15

    UniProtKB/Swiss-Prot: COX20_HUMAN, Q5RI15
    Similarity: Belongs to the COX20 family


    Find genes that share domains with COX20           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX20
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for COX20

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX20
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COX20

    miRNA
    Products:
        
    miRTarBase miRNAs that target COX20:
    hsa-mir-375 (MIRT019839)

    Block miRNA regulation of human, mouse, rat COX20 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COX20
    SwitchGear 3'UTR luciferase reporter plasmidCOX20 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for COX20
    Predesigned siRNA for gene silencing in human, mouse, rat COX20

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for COX20

    Clone
    Products:
         
    OriGene clones in human, mouse for COX20 (see all 6)
    OriGene ORF clones in mouse, rat for COX20
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for COX20
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX20

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for COX20
    Browse ESI BIO Cell Lines and PureStem Progenitors for COX20 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX20


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    COX20_HUMAN, Q5RI15: Mitochondrion membrane; Multi-pass membrane protein (Potential)

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0016021integral component of membrane IEA--
    GO:0031966mitochondrial membrane IEA--

    Find genes that share ontologies with COX20           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COX20
    Interactions:

        Search GeneGlobe Interaction Network for COX20

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for COX20 (ENSP000004063274) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COX20



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for COX20 gene: 
    NM_198076.4  

    Unigene Cluster for COX20:

    COX20 Cox2 chaperone homolog (S. cerevisiae)
    Hs.411490  [show with all ESTs]
    Unigene Representative Sequence: NM_198076
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000411948(uc001iar.3 uc001ias.3 uc001iat.3) ENST00000366528
    ENST00000391839 ENST00000498262 ENST00000464757
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat COX20 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COX20
    SwitchGear 3'UTR luciferase reporter plasmidCOX20 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for COX20
    Predesigned siRNA for gene silencing in human, mouse, rat COX20
    Clone
    Products:
         
    OriGene clones in human, mouse for COX20 (see all 6)
    OriGene ORF clones in mouse, rat for COX20
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for COX20
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX20
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for COX20
    OriGene qSTAR qPCR primer pairs in human, mouse for COX20
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COX20
      QuantiTect SYBR Green Assays in human, mouse, rat COX20
      QuantiFast Probe-based Assays in human, mouse, rat COX20

    Additional mRNA sequence: 

    AF086182.1 AK000866.1 AK054764.1 AK125259.1 AK130498.1 AK300760.1 AL122072.1 BC018519.1 
    BC062419.1 BC064399.1 BC095486.1 

    Selected DOTS entries (see all 27):

    DT.113374  DT.101985133  DT.100825637  DT.87015863  DT.99975590  DT.95214998  DT.100825636  DT.121445583 
    DT.91640722  DT.95315522  DT.92416950  DT.121445647  DT.91674190  DT.92004008  DT.97846192  DT.99944880 
    DT.99995020  DT.121238954  DT.121445586  DT.121445619  DT.91721453  DT.91749453  DT.91913730  DT.100825631 

    Selected AceView cDNA sequences (see all 232):

    D11993 AF086182 BC018519 BX442469 BC062419 AI627303 BI325004 CB853753 
    BU738667 AI140960 CR592197 BQ189361 AI690043 AA732463 CB132534 N74633 
    BU687773 BI258748 BM771333 BG027599 BQ009739 CD677338 AA643904 BC064399 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    COX20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCAATAAGC
    COX20 Expression
    About this image


    COX20 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
    COX20 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COX20 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.411490
        Custom PCR Arrays for COX20
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for COX20
    OriGene qSTAR qPCR primer pairs in human, mouse for COX20
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COX20
    QuantiTect SYBR Green Assays in human, mouse, rat COX20
    QuantiFast Probe-based Assays in human, mouse, rat COX20
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for COX20 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox201 , 5 family with sequence similarity 36, member A5
    COX20 Cox2 chaperone1
    83.02(n)1
    82.08(a)1
      1 (83.16 cM)5
    663591  NM_025511.21  NP_079787.11 
     1783191305 
    chicken
    (Gallus gallus)
    Aves COX201 COX20 Cox2 chaperone homolog (S. cerevisiae) 69.61(n)
    63.73(a)
      421493  NM_001277664.1  NP_001264593.1 
    lizard
    (Anolis carolinensis)
    Reptilia COX206
    COX20 cytochrome C oxidase assembly factor
    58(a)
    1 ↔ 1
    GL343285.1(1218326-1225062)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004976661 cytochrome c oxidase protein 20 homolog 63.78(n)
    64.42(a)
      100497666  XM_002942194.2  XP_002942240.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:925981 zgc:92598 57(n)
    60(a)
      436985  NM_001002712.1  NP_001002712.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)87Df6
    lethal (3) 87Df
    37(a)
    1 ↔ 1
    3R(8856664-8857317)


    ENSEMBL Gene Tree for COX20 (if available)
    TreeFam Gene Tree for COX20 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for COX20 gene
    1 SIMAP similar gene for COX20 using alignment to 1 protein entry:     COX20_HUMAN:
    FAM36A

    Find genes that share paralogs with COX20           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for COX20
    PGOHUM00000237182 PGOHUM00000241133


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for COX20 (see all 121)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1896290011,2
    --244996791(+) GCGCCC/TGTAAT 1 -- us2k10--------
    rs1808596331,2
    --244996944(+) ATAAAA/TCATCC 1 -- us2k10--------
    rs784014071,2
    C,F--244996949(+) TCATCC/TTTATG 1 -- us2k12Minor allele frequency- T:0.03WA NA 238
    rs1493687381,2
    C--244997015(+) TTTTC-/AAAGTCA 1 -- us2k10--------
    rs1843266541,2
    --244997098(+) ATCAAC/TAATGA 1 -- us2k10--------
    rs1439235081,2
    --244997205(+) GCAGAA/GAATCC 1 -- us2k10--------
    rs1158044761,2
    C,F--244997261(+) CTAGCA/TAACAG 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1896372651,2
    --244997304(+) ACGGAC/GTTTCG 1 -- us2k10--------
    rs1472791701,2
    C--244997332(+) GAGTAC/GAGTGG 1 -- us2k10--------
    rs1812323351,2
    --244997532(+) CAGCCC/TCCAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COX20 (244998624 - 245008359 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for COX20: --
    Human Gene Mutation Database (HGMD): COX20
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing COX20
    DNA2.0 Custom Variant and Variant Library Synthesis for COX20

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 614698   
    OMIM disorders: 220110  
    1 disease for COX20:    
    About MalaCards
    cytochrome-c oxidase deficiency disease


    Find genes that share disorders with COX20           About GenesLikeMe


    Export disorders for COX20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for COX20 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with COX20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. (PubMed id 22356826)1, 2, 3 Szklarczyk R.... Huynen M.A. (Genome Biol. 2012)
    2. A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia. (PubMed id 23125284)1, 3 Szklarczyk R....van den Heuvel L.P. (Hum. Mol. Genet. 2013)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Molecular characterization of 1q44 microdeletion in 11 patients reveals three candidate genes for intellectual disability and seizures. (PubMed id 22678713)1 Thierry G....Le Caignec C. (Am. J. Med. Genet. A 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 116228 HGNC: 26970 AceView: FAM36A Ensembl:ENSG00000203667 euGenes: HUgn116228
    ECgene: COX20 H-InvDB: COX20

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for COX20 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for COX20 gene:
    Search GeneIP for patents involving COX20

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for COX20  
     OriGene qPCR primer pairs and template standards for COX20   OriGene Protein Over-expression Lysate for COX20  
     OriGene MassSpec something-or-other for COX20   OriGene clones in human, mouse for COX20  
     OriGene qSTAR qPCR primer pairs in human, mouse for COX20   OriGene Purified Protein for COX20  
     OriGene ORF clones in mouse, rat for COX20   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for COX20   OriGene Custom Protein Services for COX20  

     
     
     Block miRNA regulation of human, mouse, rat COX20 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing COX20
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX20 Predesigned siRNA for gene silencing in human, mouse, rat COX20
     QuantiFast Probe-based Assays in human, mouse, rat COX20 QuantiTect SYBR Green Assays in human, mouse, rat COX20
     Custom PCR Arrays for COX20 Search Chromatin IP Primers for COX20
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COX20 Search GeneGlobe Interaction Network for COX20
     Search Regulatory tfbs for COX20
     GenScript Custom Purified and Recombinant Proteins Services for COX20 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for COX20
     GenScript Custom Assay Services for COX20 GenScript Custom overexpressing Cell Line Services for COX20
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for COX20
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     COX20 antibodies
     COX20 lysates
     Search for Antibodies for COX20 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for COX20
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for COX20
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX20
     SwitchGear 3'UTR luciferase reporter plasmids for COX20
     SwitchGear Promoter luciferase reporter plasmids for COX20
     Search ThermoFisher Antibodies for COX20
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX20
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX20
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for COX20
     LSBio Antibodies in human, mouse, rat for COX20
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for COX20
      Search eBioscience for proteins for COX20
      Search eBioscience for elisas for COX20
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      COX20 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4