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COX19 Gene

protein-coding   GIFtS: 43
GCID: GC07M000939

Cytochrome C Oxidase Assembly Homolog 19 (S. Cerevisiae)

(Previous name: COX19 cytochrome c oxidase assembly homolog (S. cerevisiae))
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cytochrome C Oxidase Assembly Homolog 19 (S. Cerevisiae)1 2
hCOX192 3
COX19 Cytochrome C Oxidase Assembly Homolog (S. Cerevisiae)1
COX19 Cytochrome C Oxidase Assembly Homolog2
Cytochrome C Oxidase Assembly Protein COX192

External Ids:    HGNC: 280741   Entrez Gene: 906392   Ensembl: ENSG000002402307   OMIM: 6104295   UniProtKB: Q49B963   

Export aliases for COX19 gene to outside databases

Previous GC identifer: GC07M000972


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for COX19 Gene:
COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in
metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial
respiratory chain (Sacconi et al., 2005 (PubMed 16212937)).(supplied by OMIM, Mar 2008)

GeneCards Summary for COX19 Gene:
COX19 (cytochrome c oxidase assembly homolog 19 (S. cerevisiae)) is a protein-coding gene. Diseases associated with COX19 include menkes disease.

UniProtKB/Swiss-Prot: COX19_HUMAN, Q49B96
Function: May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007819.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the COX19 gene promoter:
         NF-1   NF-1/L   NRSF form 1   Bach2   MIF-1   NRSF form 2   Roaz   HEN1   SRY   Zic1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): COX19 promoter sequence
   Search Chromatin IP Primers for COX19

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

COX19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX19 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M000939:  view genomic region     (about GC identifiers)

Start:
938,415 bp from pter      End:
1,015,235 bp from pter
Size:
76,821 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 1,059,119-1,069,865     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: COX19_HUMAN, Q49B96 (See protein sequence)
Recommended Name: Cytochrome c oxidase assembly protein COX19  
Size: 90 amino acids; 10394 Da
Secondary accessions: A4FTX0

Explore the universe of human proteins at neXtProt for COX19: NX_Q49B96

Explore proteomics data for COX19 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See COX19 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001026788.1  
    ENSEMBL proteins: 
     ENSP00000413423   ENSP00000342015  

    COX19 Human Recombinant Protein Products:

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    Novus Biologicals COX19 Lysate
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    Novus Biologicals COX19 Antibodies
    Abcam antibodies for COX19
    Cloud-Clone Corp. Antibodies for COX19
    Search ThermoFisher Antibodies for COX19
    LSBio Antibodies in human, mouse, rat for COX19

    COX19 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for COX19
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for COX19
    Cloud-Clone Corp. CLIAs for COX19


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    2 InterPro protein domains:
     IPR010625 CHCH
     IPR009069 Cys_alpha_HP_mot_SF

    Graphical View of Domain Structure for InterPro Entry Q49B96

    ProtoNet protein and cluster: Q49B96

    1 Blocks protein domain: IPB010625 CHCH

    UniProtKB/Swiss-Prot: COX19_HUMAN, Q49B96
    Similarity: Belongs to the COX19 family
    Similarity: Contains 1 CHCH domain


    COX19 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COX19_HUMAN, Q49B96
    Function: May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)

    Phenotypes:
         1 MGI phenotypic allele for Cox19 (no phenotypes)


    COX19 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX19
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for COX19

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX19
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COX19

    miRNA
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    Search for qRT-PCR Assays for microRNAs that regulate COX19
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for COX19
    Predesigned siRNA for gene silencing in human, mouse, rat COX19

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for COX19

    Clone
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    OriGene clones in human, mouse for COX19 (see all 6)
    OriGene ORF clones in mouse, rat for COX19
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: COX19 (NM_001031617)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX19
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX19

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for COX19
    Browse ESI BIO Cell Lines and PureStem Progenitors for COX19 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX19


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COX19_HUMAN, Q49B96: Cytoplasm, cytosol
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol IEA--

    COX19 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COX19
    Interactions:

        Search GeneGlobe Interaction Network for COX19

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for COX19 (ENSP000003420154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHCHD4ENSP000002957674STRING: ENSP00000295767
    RHOT1ENSP000003511324STRING: ENSP00000351132
    RHOT2ENSP000003219714STRING: ENSP00000321971
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COX19



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for COX19 gene: 
    NM_001031617.2  

    Unigene Cluster for COX19:

    Cytochrome c oxidase assembly homolog 19 (S. cerevisiae)
    Hs.121593  [show with all ESTs]
    Unigene Representative Sequence: NM_001031617
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000457254 ENST00000344111(uc003sjp.1) ENST00000466146 ENST00000466853

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat COX19 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COX19
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for COX19
    Predesigned siRNA for gene silencing in human, mouse, rat COX19
    Clone
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    OriGene clones in human, mouse for COX19 (see all 6)
    OriGene ORF clones in mouse, rat for COX19
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: COX19 (NM_001031617)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX19
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX19
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for COX19
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat COX19
      QuantiTect SYBR Green Assays in human, mouse, rat COX19
      QuantiFast Probe-based Assays in human, mouse, rat COX19

    Additional mRNA sequence: 

    AK023185.1 AK130822.1 AY957566.1 BC042434.1 BC053372.1 BC058158.1 BC070383.1 BC103632.1 
    BC110420.1 

    5 DOTS entries:

    DT.100754628  DT.99983648  DT.101975144  DT.410251  DT.121061459 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    COX19 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGAAACCC
    COX19 Expression
    About this image

    COX19 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COX19 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.121593

    UniProtKB/Swiss-Prot: COX19_HUMAN, Q49B96
    Tissue specificity: Ubiquitously expressed. Highly expressed in skeletal muscle

        Custom PCR Arrays for COX19
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    QuantiFast Probe-based Assays in human, mouse, rat COX19
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX19

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for COX19 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox191 , 5 COX19 cytochrome c oxidase assembly homolog (S. cerevisiae)5
    cytochrome c oxidase assembly protein 191
    81.27(n)1
    82.02(a)1
      5 (78.40 cM)5
    680331  NM_197980.11  NP_932097.11 
     1393361895 
    chicken
    (Gallus gallus)
    Aves COX191 COX19 cytochrome c oxidase assembly homolog (S. cerevisiae) 66.67(n)
    65.17(a)
      416452  NM_001256807.1  NP_001243736.1 
    lizard
    (Anolis carolinensis)
    Reptilia COX196
    cytochrome c oxidase assembly homolog 19 (S. cerev...
    56(a)
    1 ↔ 1
    GL343385.1(724558-727596)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.341762 Xenopus laevis transcribed sequences 74.56(n)    BX853648.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1621751 zgc:162175 68.2(n)
    74.71(a)
      100004173  NM_001110540.1  NP_001104010.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG424966
    --
    36(a)
    1 ↔ 1
    2R(17579095-17580269)
    worm
    (Caenorhabditis elegans)
    Secernentea F45H11.56
    Protein F45H11.5 (F45H11.5) mRNA, complete cds
    42(a)
    1 ↔ 1
    I(10381082-10381975) WBGene00009745
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes COX19(YLL018C-A)4 Protein required for cytochrome c oxidase assembly, more   --   12(108972-108676) 850642  NP_013082.1 


    ENSEMBL Gene Tree for COX19 (if available)
    TreeFam Gene Tree for COX19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for COX19 gene

    COX19 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for COX19
    PGOHUM00000235154


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for COX19 (see all 300)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs586925471,2
    C--1003999(+) AACAA-/TTTTTT 1 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs69614241,2
    C,F,A,H--1004113(+) acaggC/Tgtggg 1 -- int120Minor allele frequency- T:0.28EA NS NA WA CSA 1319
    rs1845997071,2
    --1004205(+) GTAATC/TTGTTA 1 -- int10--------
    rs69491941,2
    C,F,A--1004211(+) TGTTAC/GTGTGG 1 -- int111Minor allele frequency- G:0.44NA WA CSA EA 373
    rs778322541,2
    C,F--1004228(+) GAACCG/AATACA 1 -- int11Minor allele frequency- A:0.02EA 120
    rs132287631,2
    C,F,H--1004248(+) AGGAAG/CTCAGT 1 -- int111Minor allele frequency- C:0.09NS EA NA WA 748
    rs117690261,2
    C,H--1004323(+) CAAACA/GAGGCC 1 -- int10--------
    rs1505468331,2
    --1004427(+) CCTGCA/GACCAC 1 -- int10--------
    rs1810339791,2
    --1004442(+) CCTCCC/GGTTTA 1 -- int10--------
    rs23971,2
    C,F,O,H--1004523(+) CAGCTT/AATCAT 1 -- ut3127Minor allele frequency- A:0.14MN NS EA NA WA CSA 2958

    HapMap Linkage Disequilibrium report for COX19 (938415 - 1015235 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for COX19 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509182CNV Insertion20534489
    dgv7083n71CNV Loss21882294
    dgv7081n71CNV Loss21882294
    nsv887128CNV Loss21882294
    dgv7078n71CNV Loss21882294
    nsv823958CNV Loss20364138
    nsv887141CNV Loss21882294
    nsv464244CNV Loss19166990
    dgv7082n71CNV Loss21882294
    dgv7074n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing COX19
    DNA2.0 Custom Variant and Variant Library Synthesis for COX19

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610429    OMIM disorders: --

    1 disease for COX19:    
    About MalaCards
    menkes disease

    1 disease from the University of Copenhagen DISEASES database for COX19:
    Menkes disease

    COX19 for disorders           About GeneDecksing


    Export disorders for COX19 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for COX19 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with COX19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hCOX18 and hCOX19: two human genes involved in cytochrome c oxidase assembly. (PubMed id 16212937)1, 2, 3 Sacconi S....Salviati L. (Biochem. Biophys. Res. Commun. 2005)
    2. Studies of COX16, COX19, and PET191 in human cytochrome-c oxidase deficiency. (PubMed id 15596615)1, 3 Tay S.K.H.... Dimauro S. (Arch. Neurol. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. (PubMed id 23897914)1 Wang H....O'Brodovich H.M. (Pediatrics 2013)
    5. COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. (PubMed id 23345593)1 Leary S.C....Shoubridge E.A. (Mol. Biol. Cell 2013)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 90639 HGNC: 28074 Ensembl:ENSG00000240230 euGenes: HUgn90639 ECgene: COX19
    H-InvDB: COX19

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for COX19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for COX19 gene:
    Search GeneIP for patents involving COX19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for COX19   OriGene RNAi products in human, mouse, rat for COX19  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for COX19  
     OriGene MassSpec something-or-other for COX19   OriGene clones in human, mouse for COX19  
     OriGene qSTAR qPCR primer pairs in human, mouse for COX19   OriGene Purified Protein for COX19  
     OriGene ORF clones in mouse, rat for COX19   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for COX19   OriGene Custom Protein Services for COX19  

     
     
     Block miRNA regulation of human, mouse, rat COX19 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing COX19
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX19 Predesigned siRNA for gene silencing in human, mouse, rat COX19
     QuantiFast Probe-based Assays in human, mouse, rat COX19 QuantiTect SYBR Green Assays in human, mouse, rat COX19
     Custom PCR Arrays for COX19 Search Chromatin IP Primers for COX19
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat COX19  Search GeneGlobe Interaction Network for COX19
     Regulatory tfbs in COX19 promoter
     GenScript Custom Purified and Recombinant Proteins Services for COX19 GenScript cDNA clones with any tag delivered in your preferred vector for COX19
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     Search Tocris compounds for COX19
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     See all of Abcam's Antibodies, Kits and Proteins for COX19
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     Abcam protocols and scientific support
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     Proteins for COX19
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     Browse ESI BIO Cell Lines and PureStem Progenitors for COX19
     Gene Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX19
     Browse SwitchGear 3'UTR luciferase reporter plasmids for COX19
     SwitchGear Promoter luciferase reporter plasmids for COX19
     Search ThermoFisher Antibodies for COX19
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX19
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX19
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for COX19
     LSBio Antibodies in human, mouse, rat for COX19
    Customized transgenic rodents for:
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     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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