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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COX18 Gene

protein-coding   GIFtS: 44
GCID: GC04M073920

COX18 Cytochrome C Oxidase Assembly Factor

(Previous names: COX18 cytochrome c oxidase assembly homolog (S. cerevisiae),...)
  Search for COX18
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
COX18 Cytochrome C Oxidase Assembly Factor1 2     Cox18Hs2 Protein2
Cytochrome C Oxidase Assembly Protein 182 3     Cox18Hs3 Protein2
COX18 Cytochrome C Oxidase Assembly Homolog (S. Cerevisiae)1     Cytochrome C Oxidase Assembly Homolog 182
Cytochrome C Oxidase Assembly Homolog 18 (Yeast)1     Mitochondrial COX182
COX18HS2     Mitochondrial Inner Membrane Protein COX182
COX18 Cytochrome C Oxidase Assembly Homolog2     COX18Hs3
Cox18Hs1 Protein2     OXA1L23

External Ids:    HGNC: 268011   Entrez Gene: 2855212   Ensembl: ENSG000001636267   OMIM: 6104285   UniProtKB: Q8N8Q83   

Export aliases for COX18 gene to outside databases

Previous GC identifers: GC04M074139 GC04M069726


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COX18 Gene:
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the
insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate
step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 (PubMed
16212937)).(supplied by OMIM, Mar 2008)

GeneCards Summary for COX18 Gene: 
COX18 (COX18 cytochrome C oxidase assembly factor) is a protein-coding gene. GO annotations related to this gene include protein transporter activity. An important paralog of this gene is OXA1L.

UniProtKB/Swiss-Prot: COX18_HUMAN, Q8N8Q8
Function: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane.
Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and
export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_022778.16  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COX18 gene promoter:
         AhR   AML1a   CUTL1   LCR-F1   Ik-2   FOXO4   FOXO1a   FOXO1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOX18 promoter sequence
   Search SABiosciences Chromatin IP Primers for COX18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COX18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

COX18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX18 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M073920:  view genomic region     (about GC identifiers)

Start:
73,920,416 bp from pter      End:
73,935,472 bp from pter
Size:
15,057 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COX18_HUMAN, Q8N8Q8 (See protein sequence)
Recommended Name: Mitochondrial inner membrane protein COX18 precursor  
Size: 333 amino acids; 37063 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAH71812.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q2PB66 Q2PB67 Q2PB68 Q49B97 Q6IPP9
Alternative splicing: 4 isoforms:  Q8N8Q8-1   Q8N8Q8-2   Q8N8Q8-3   Q8N8Q8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COX18: NX_Q8N8Q8

Explore proteomics data for COX18 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N8Q8

  • COX18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COX18 Protein Expression
    REFSEQ proteins: NP_776188.1  
    ENSEMBL proteins: 
     ENSP00000295890   ENSP00000394583   ENSP00000425261   ENSP00000424978  

    Human Recombinant Protein Products for COX18: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for COX18 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0016021integral to membrane ----
    GO:0031305integral to mitochondrial inner membrane IDA16212937

    COX18 for ontologies           About GeneDecksing



    COX18 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for COX18


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    1 InterPro protein domain:
     IPR001708 Membrane_insert_OXA1/ALB3/YidC

    Graphical View of Domain Structure for InterPro Entry Q8N8Q8

    ProtoNet protein and cluster: Q8N8Q8

    UniProtKB/Swiss-Prot: COX18_HUMAN, Q8N8Q8
    Similarity: Belongs to the OXA1/ALB3/YidC family


    COX18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COX18_HUMAN, Q8N8Q8
    Function: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane.
    Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and
    export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008565protein transporter activity IGI16911509
         
    COX18 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for COX18:
     Increased cell number in G2M,   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for COX18 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX18 
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    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate COX18 (see all 13):
    hsa-miR-217 hsa-miR-3671 hsa-miR-206 hsa-miR-576-5p hsa-miR-607 hsa-miR-1 hsa-miR-3647-3p hsa-miR-500a
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX18


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COX18

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008535respiratory chain complex IV assembly IGI16911509
    GO:0015031protein transport IGI16911509
    GO:0051204protein insertion into mitochondrial membrane IGI16911509
    GO:0051205protein insertion into membrane ----

    COX18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COX18

    Search CenterWatch for drugs/clinical trials and news about COX18

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COX18 gene (2 alternative transcripts): 
    NM_001033760.1  NM_173827.2  

    Unigene Cluster for COX18:

    Cytochrome c oxidase assembly homolog 18 (yeast)
    Hs.356697  [show with all ESTs]
    Unigene Representative Sequence: NM_173827
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000295890(uc003hgm.1 uc003hgn.1 uc011cbc.1) ENST00000449739(uc010iih.1)
    ENST00000507544 ENST00000510031 ENST00000421792
    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate COX18 (see all 13):
    hsa-miR-217 hsa-miR-3671 hsa-miR-206 hsa-miR-576-5p hsa-miR-607 hsa-miR-1 hsa-miR-3647-3p hsa-miR-500a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COX18

    Additional mRNA sequence: 

    AK092641.1 AK096310.2 AM055750.1 AM055751.1 AM055752.1 BC071812.1 BC101684.1 BC143642.1 

    6 DOTS entries:

    DT.314864  DT.95367294  DT.99945744  DT.99966529  DT.40190506  DT.100749764 

    24/86 AceView cDNA sequences (see all 86):

    BE326447 AA412740 T08528 AW519319 AI024757 BM668855 AI368777 BE047663 
    BU619518 BG283902 AA449445 AA938348 BX116684 BM804180 BC071812 AI302410 
    AA770199 CB857042 AI208464 BG109286 AA601548 N29053 AI042199 N20674 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for COX18    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            


    ECgene alternative splicing isoforms for COX18

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COX18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    COX18 Expression
    About this image


    See COX18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COX18

    SOURCE GeneReport for Unigene cluster: Hs.356697
        SABiosciences Expression via Pathway-Focused PCR Array including COX18: 
              Mitochondria in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX18

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for COX18 gene from 8/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox181 , 5 COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)5
    cytochrome c oxidase assembly protein 181
    77.88(n)1
    78.79(a)1
      5 (44.32 cM)5
    2314301  NM_001163456.11  NP_001156928.11 
     902147245 
    chicken
    (Gallus gallus)
    Aves COX181 COX18 cytochrome c oxidase assembly homolog (S. cerevisiae) 66.44(n)
    61.82(a)
      422650  XM_420604.3  XP_420604.2 
    lizard
    (Anolis carolinensis)
    Reptilia COX186
    cytochrome c oxidase assembly homolog 18 (yeast)
    65(a)
    1 ↔ 1
    6(59862024-59872091)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.261542 Xenopus laevis transcribed sequence with weak similarity more 72.02(n)    CD360564.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1748641 zgc:174864 60.1(n)
    59.14(a)
      100000948  NM_001114469.1  NP_001107941.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG49421 CG4942 53.21(n)
    41.82(a)
      39044  NM_140029.3  NP_648286.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y55F3AR.16
    C01A2.36
    Protein C01A2.3
    21(a)
    15(a)
    1 ↔ 1
    possible ortholog
    IV(1097451-1102981)
    I(13387817-13391450)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes OXA16
    Mitochondrial inner membrane insertase, mediates t...
    14(a)
    1 → many
    V(475020-476228)


    ENSEMBL Gene Tree for COX18 (if available)
    TreeFam Gene Tree for COX18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COX18 gene
    OXA1L2  

    COX18 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/370 SNPs in COX18 are shown (see all 370)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512628621,2
    --73920047(+) TGCAAC/TTTTCT 1 -- ds50010--------
    rs1926614731,2
    --73920103(+) TGAAGA/GAAAAA 1 -- ds50010--------
    rs1396342001,2
    --73920555(+) CCTGGA/CCACAA 1 -- ut310--------
    rs728618101,2
    C--73920558(+) GGCCAC/AAAGGA 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs10520801,2
    C,F,O,H--73920622(-) CTTTTG/ATATGC 1 -- ut31 ese321Minor allele frequency- A:0.30MN NS EA NA WA 2526
    rs1829779411,2
    --73920648(+) GATTCC/TGCTGG 1 -- ut310--------
    rs1180330961,2
    F--73920719(+) TTTGCG/ATCTCA 1 -- ut311Minor allele frequency- A:0.01EA 120
    rs1154394251,2
    C,F--73920836(+) ATGAGA/GAAAAT 1 -- ut311Minor allele frequency- G:0.02WA 118
    rs1884876151,2
    --73920927(+) ATTCTC/TTCCTC 1 -- ut310--------
    rs1931748851,2
    --73920975(+) TCTGCA/CTCCTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for COX18 (73920416 - 73935472 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for COX18:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv523169CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing COX18
    DNA2.0 Custom Variant and Variant Library Synthesis for COX18

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    COX18 for disorders           About MalaCards
    OMIM gene information: 610428    OMIM disorders: --


    COX18 for disorders           About GeneDecksing

    Genetic Association Database (GAD): COX18
    Human Genome Epidemiology (HuGE) Navigator: COX18 (4 documents)

    Export disorders for COX18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COX18 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with COX18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The COX18 gene, involved in mitochondrial biogenesis, is functionally conserved and tightly regulated in humans and fission yeast. (PubMed id 16911509)1, 2, 3, 9 Gaisne M. and Bonnefoy N. (2006)
    2. hCOX18 and hCOX19: two human genes involved in cytochrome c oxidase assembly. (PubMed id 16212937)1, 2, 3 Sacconi S....Salviati L. (2005)
    3. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage he ad and neck cancer. (PubMed id 20819778)1, 4 Zhang X....Wu X. (2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)
    9. Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. (PubMed id 21546767)1 Murea M....Freedman B.I. (2011)
    10. Genome-wide pleiotropy of osteoporosis-related phenot ypes: The Framingham study. (PubMed id 20200953)1 Karasik D....Demissie S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 285521 HGNC: 26801 AceView: FLJ38991 Ensembl:ENSG00000163626 euGenes: HUgn285521
    ECgene: COX18 H-InvDB: COX18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COX18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COX18 gene:
    Search GeneIP for patents involving COX18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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