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COX14 Gene

protein-coding   GIFtS: 38
GCID: GC12P050509

Cytochrome C Oxidase Assembly Homolog 14 (S. Cerevisiae)

(Previous names: chromosome 12 open reading frame 62, COX14 cytochrome c...)
(Previous symbol: C12orf62)
  See COX14-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cytochrome C Oxidase Assembly Homolog 14 (S. Cerevisiae)1 2
C12orf621 2 3 5
Chromosome 12 Open Reading Frame 621
COX14 Cytochrome C Oxidase Assembly Homolog (S. Cerevisiae)1
COX14 Cytochrome C Oxidase Assembly Homolog2
Cytochrome C Oxidase Assembly Protein COX142

External Ids:    HGNC: 282161   Entrez Gene: 849872   Ensembl: ENSG000001784497   OMIM: 6144785   UniProtKB: Q96I363   

Export aliases for COX14 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for COX14 Gene:
This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play
a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subunit assembly
and, in particular, the synthesis and assembly of the COX I subunit of the holoenzyme. Mutations in this gene
have been associated with mitochondrial complex IV deficiency. Alternative splicing results in multiple
transcript variants. (provided by RefSeq, Nov 2012)

GeneCards Summary for COX14 Gene:
COX14 (cytochrome c oxidase assembly homolog 14 (S. cerevisiae)) is a protein-coding gene. Diseases associated with COX14 include cytochrome-c oxidase deficiency disease.

UniProtKB/Swiss-Prot: COX14_HUMAN, Q96I36
Function: Plays a role in the assembly or stability of the cytochrome c oxidase complex (COX). Requires for
coordination of the early steps of COX assembly with the synthesis of MT-CO1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for COX14
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for COX14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

COX14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COX14 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P050509:  view genomic region     (about GC identifiers)

Start:
50,505,762 bp from pter      End:
50,514,240 bp from pter
Size:
8,479 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: COX14_HUMAN, Q96I36 (See protein sequence)
Recommended Name: Cytochrome c oxidase assembly protein COX14  
Size: 57 amino acids; 6600 Da
Subunit: Component of some MITRAC complex
Secondary accessions: B2R5G6

Explore the universe of human proteins at neXtProt for COX14: NX_Q96I36

Explore proteomics data for COX14 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See COX14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001244062.1  NP_001244063.1  NP_116290.1  

    ENSEMBL proteins: 
     ENSP00000446524   ENSP00000326052   ENSP00000450331   ENSP00000447776  

    COX14 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for COX14
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    Novus Biologicals COX14 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for COX14 

    COX14 Antibody Products:

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    COX14 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for COX14 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    ProtoNet protein and cluster: Q96I36


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COX14_HUMAN, Q96I36
    Function: Plays a role in the assembly or stability of the cytochrome c oxidase complex (COX). Requires for
    coordination of the early steps of COX assembly with the synthesis of MT-CO1

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX14
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COX14
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COX14

    miRNA
    Products:
        
    miRTarBase miRNAs that target COX14:
    hsa-let-7e-5p (MIRT051682), hsa-let-7a-5p (MIRT052620)

    Block miRNA regulation of human, mouse, rat COX14 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COX14
    SwitchGear 3'UTR luciferase reporter plasmidCOX14 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat COX14

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX14

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COX14_HUMAN, Q96I36: Mitochondrion membrane; Single-pass membrane protein

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0016021integral component of membrane IEA--
    GO:0031966mitochondrial membrane IEA--

    Find genes that share ontologies with COX14           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COX14
    Interactions:

        Search GeneGlobe Interaction Network for COX14

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for COX14 (ENSP000003260524) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COX17ENSP000002610704STRING: ENSP00000261070
    MT-CO1ENSP000003544994STRING: ENSP00000354499
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0033617mitochondrial respiratory chain complex IV assembly TAS--

    Find genes that share ontologies with COX14           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COX14



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for COX14 gene (3 alternative transcripts): 
    NM_001257133.1  NM_001257134.1  NM_032901.3  

    Unigene Cluster for COX14:

    Cytochrome c oxidase assembly homolog 14 (S. cerevisiae)
    Hs.388645  [show with all ESTs]
    Unigene Representative Sequence: BI116796
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000550487(uc001rwb.1) ENST00000317943 ENST00000550654 ENST00000548985

    miRNA
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    Block miRNA regulation of human, mouse, rat COX14 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COX14
    SwitchGear 3'UTR luciferase reporter plasmidCOX14 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for COX14
    Predesigned siRNA for gene silencing in human, mouse, rat COX14
    Clone
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    OriGene ORF clones in mouse, rat for COX14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for COX14
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COX14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX14
    Primer
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    OriGene qPCR primer pairs and template standards for COX14
    OriGene qSTAR qPCR primer pairs in human, mouse for COX14
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COX14
      QuantiTect SYBR Green Assays in human, mouse, rat COX14
      QuantiFast Probe-based Assays in human, mouse, rat COX14

    Additional mRNA sequence: 

    AK312180.1 BC007849.2 

    11 DOTS entries:

    DT.446561  DT.95315693  DT.121183263  DT.95171855  DT.95171856  DT.100818480  DT.121183257  DT.97787084 
    DT.100818483  DT.91667377  DT.92043940 

    Selected AceView cDNA sequences (see all 227):

    AA235287 AA313833 BU162058 BM920325 AW008787 AI571201 AA303477 BC007849 
    AJ346784 BM667896 AA280017 F30199 BU731504 AA706689 BM696534 F36871 
    AA838682 T25729 BQ920060 BM451907 CB135858 AI333959 CD106922 AA255455 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for COX14    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b · 4c
    SP1:                          -           -                     
    SP2:                          -     -                           
    SP3:                          -     -     -                     
    SP4:                                -     -                     


    ECgene alternative splicing isoforms for COX14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    COX14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTTCTCTGG
    COX14 Expression
    About this image

    COX14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COX14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.388645
        Custom PCR Arrays for COX14
    Primer
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    OriGene qPCR primer pairs and template standards for COX14
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COX14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for COX14 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cox141 , 5 RIKEN cDNA 2310016M24 gene5
    cytochrome c oxidase assembly protein 141
    85.38(n)1
    80.7(a)1
      15 (56.13 cM)5
    663791  NM_183256.31  NP_899079.11 
     997256185 
    lizard
    (Anolis carolinensis)
    Reptilia COX146
    cytochrome c oxidase assembly homolog 14 (S. cerev...
    61(a)
    1 ↔ 1
    2(91623172-91623339)
    zebrafish
    (Danio rerio)
    Actinopterygii cox146
    cytochrome c oxidase assembly homolog 14 (S. cerev...
    30(a)
    1 ↔ 1
    22(5676344-5680471) ENSDARG00000092124


    ENSEMBL Gene Tree for COX14 (if available)
    TreeFam Gene Tree for COX14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for COX14 (see all 251)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1385236681,2
    --50337428(+) CCCCTA/CCCCCA 3 -- us2k10--------
    rs1178014121,2
    C,F--50337480(+) AGCTCG/AGTGGC 3 -- us2k11Minor allele frequency- A:0.01EA 120
    rs744494831,2
    C,F--50337657(+) CTCAGC/TTCCCT 3 -- us2k11Minor allele frequency- T:0.03WA 118
    rs731235161,2
    --50337716(+) GGAGGA/TGTCAG 3 -- us2k10--------
    rs1896233081,2
    --50337816(+) CCAGAA/CCGGCC 3 -- us2k10--------
    rs1813051551,2
    --50337892(+) ATGAAC/TGGTAG 3 -- us2k10--------
    rs1383568811,2
    C--50338078(+) GGAGG-/GGAGGAGG 3 -- us2k10--------
    rs2005226981,2
    --50338089(+) GGAGG-/AGTGTGCT 3 -- us2k10--------
    rs1160286411,2
    C,F--50338123(+) ATGGGG/ATGGCA 3 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1440249201,2
    C--50338195(+) AGAGGC/GTCCCG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for COX14 (50505762 - 50514240 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for COX14: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing COX14
    DNA2.0 Custom Variant and Variant Library Synthesis for COX14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614478   
    OMIM disorders: 220110  
    UniProtKB/Swiss-Prot: COX14_HUMAN, Q96I36
  • Note=Defects in COX14 may be a cause of a mitochondrial disorder presenting with severe congenital lactic
    acidosis and dysmorphic features associated with a COX assembly defect. Other features include brain hypertrophy,
    diffuse alteration of the white-matter myelination, and numerous cavities in the parieto-occipital region,
    brainstem, and cerebellum, as well as hepatomegaly, hypertrophic cardiomyopathy, renal hypoplasia, and
    adrenal-gland hyperplasia

  • 1 disease for COX14:    
    About MalaCards
    cytochrome-c oxidase deficiency disease


    Find genes that share disorders with COX14           About GenesLikeMe


    Export disorders for COX14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for COX14 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with COX14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. (PubMed id 22356826)1, 2, 3 Szklarczyk R.... Huynen M.A. (Genome Biol. 2012)
    2. Mutations in C12orf62, a factor that couples COX I synthesis with cytochrome c oxidase assembly, cause fatal neonatal lactic acidosis. (PubMed id 22243966)1, 2, 3 Weraarpachai W.... Shoubridge E.A. (Am. J. Hum. Genet. 2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. (PubMed id 23260140)2 Mick D.U.... Rehling P. (Cell 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    10. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84987 HGNC: 28216 AceView: MGC14288 Ensembl:ENSG00000178449 euGenes: HUgn84987
    ECgene: COX14 H-InvDB: COX14

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for COX14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for COX14 gene:
    Search GeneIP for patents involving COX14

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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for COX14  
     OriGene qPCR primer pairs and template standards for COX14   OriGene Protein Over-expression Lysate for COX14  
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     OriGene Custom Antibody Services for COX14   OriGene Custom Protein Services for COX14  

     
     
     Block miRNA regulation of human, mouse, rat COX14 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing COX14
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COX14 Predesigned siRNA for gene silencing in human, mouse, rat COX14
     QuantiFast Probe-based Assays in human, mouse, rat COX14 QuantiTect SYBR Green Assays in human, mouse, rat COX14
     Custom PCR Arrays for COX14 Search Chromatin IP Primers for COX14
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COX14 Search GeneGlobe Interaction Network for COX14
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     Search Tocris compounds for COX14
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     Novus Tissue Slides
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     Search for Antibodies for COX14 at Abcam
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     Browse Proteins at Cloud-Clone Corp.
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     Browse ESI BIO Cell Lines and PureStem Progenitors for COX14
     Gene Synthesis
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     Search ThermoFisher Antibodies for COX14
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COX14
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COX14
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     Search LSBio for Antibodies for COX14
    Customized transgenic rodents for:
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     Browse compounds at ApexBio
     Search Addgene for plasmids for COX14
      Search eBioscience for proteins for COX14
      Search eBioscience for elisas for COX14
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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