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CORT Gene

protein-coding   GIFtS: 51
GCID: GC01P010509

Cortistatin

  See CORT-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
cortistatin1 2     cortistatin-142
prepro-cortistatin1 2     cortistatin-172
CST-142     cortistatin-292
CST-172     preprocortistatin2
CST-292     

External Ids:    HGNC: 22571   Entrez Gene: 13252   Ensembl: ENSG000002415637   OMIM: 6027845   UniProtKB: O002303   

Export aliases for CORT gene to outside databases

Previous GC identifers: GC01P010471 GC01P010333 GC01P010099 GC01P010199 GC01P010424 GC01P009663


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CORT Gene:
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin
receptors, and shares many pharmacological and functional properties with somatostatin, including the depression
of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of
slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of
locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein
undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and
the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. (provided
by RefSeq, Nov 2010)

GeneCards Summary for CORT Gene:
CORT (cortistatin) is a protein-coding gene. Diseases associated with CORT include intestinal disease. GO annotations related to this gene include neuropeptide hormone activity and G-protein coupled receptor binding.

UniProtKB/Swiss-Prot: CORT_HUMAN, O00230
Function: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by
forskolin through SSTRs

Gene Wiki entry for CORT (Cortistatin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the CORT gene promoter:
         GR   p53   Pax-6   GR-beta   CUTL1   c-Ets-1   STAT3   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CORT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CORT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.22   Ensembl cytogenetic band:  1p36.22   HGNC cytogenetic band: 1p36.22

CORT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CORT gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P010509:  view genomic region     (about GC identifiers)

Start:
10,509,776 bp from pter      End:
10,512,060 bp from pter
Size:
2,285 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CORT_HUMAN, O00230 (See protein sequence)
Recommended Name: Cortistatin precursor  
Size: 105 amino acids; 11532 Da
Sequence caution: Sequence=AAI19725.1; Type=Erroneous initiation; Sequence=AAI19726.1; Type=Erroneous initiation;
Sequence=AAQ89950.1; Type=Erroneous initiation; Sequence=CAI19195.1; Type=Erroneous initiation;
Sequence=EAW71650.1; Type=Erroneous initiation;
Secondary accessions: Q5T6G0 Q6UX11

Explore the universe of human proteins at neXtProt for CORT: NX_O00230

Explore proteomics data for CORT at MOPED


See CORT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001293.3  
ENSEMBL proteins: 
 ENSP00000366248   ENSP00000317110  

CORT Human Recombinant Protein Products:

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Novus Biologicals CORT Lysate
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Cloud-Clone Corp. Proteins for CORT

 
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antibodies-online proteins for CORT (2 products) 

 
antibodies-online peptides for CORT

CORT Antibody Products:

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antibodies-online antibodies for CORT (17 products) 

CORT Assay Products:

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Cloud-Clone Corp. CLIAs for CORT
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antibodies-online kits for CORT (27 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ENDOLIG: Endogenous ligands

1 InterPro protein domain:
 IPR018142 Somatostatin/Cortistatin_C

Graphical View of Domain Structure for InterPro Entry O00230

ProtoNet protein and cluster: O00230

1 Blocks protein domain: IPB004250 Somatostatin/Cortistatin

UniProtKB/Swiss-Prot: CORT_HUMAN, O00230
Similarity: Belongs to the somatostatin family


Find genes that share domains with CORT           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CORT_HUMAN, O00230
Function: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by
forskolin through SSTRs

     Genatlas biochemistry entry for CORT:
preprocortistatin,expressed in GABAergic interneurons in the cerebral cortex and hippocampus,highly homologous to
somatostatin,not tumor suppressor for neuroblastoma

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001664G-protein coupled receptor binding IPI12915402
GO:0005179hormone activity ----
GO:0005184neuropeptide hormone activity IDA9125122
     
Find genes that share ontologies with CORT           About GenesLikeMe


Phenotypes:
     4 GenomeRNAi human phenotypes for CORT:
 Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Increased gamma-H2AX phosphory 

     5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cort):
 behavior/neurological  endocrine/exocrine gland  growth/size/body  homeostasis/metabolism  normal 

Find genes that share phenotypes with CORT           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Corttm1Ldl for CORT

   genOway: Develop your customized and physiologically relevant rodent model for CORT

miRNA
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2 qRT-PCR Assays for microRNAs that regulate CORT:
hsa-miR-374c hsa-miR-655
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GenScript: all cDNA clones in your preferred vector: CORT (NM_001302)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for CORT
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CORT

Cell Line
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORT


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CORT_HUMAN, O00230: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
cytosol2
nucleus2
plasma membrane2
cytoskeleton1
endoplasmic reticulum1
mitochondrion1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region ----
GO:0005615extracellular space NAS9125122

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for CORT About    
See pathways by source

SuperPathContained pathways About
1Mitotic Metaphase and Anaphase
Mitotic Anaphase0.94
Mitotic Metaphase and Anaphase0.93
Separation of Sister Chromatids0.94
2Cell Cycle, Mitotic
Cell Cycle, Mitotic0.90
M Phase0.62
Cell Cycle0.90
3Mitotic Prometaphase
Mitotic Prometaphase0.92
Resolution of Sister Chromatid Cohesion0.92




    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CORT
Interactions:

    GeneGlobe Interaction Network for CORT

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

Selected Interacting proteins for CORT (O002303 ENSP000003171104) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
InteractantInteraction Details
GeneCardExternal ID(s)
SSTR1P308723I2D: score=1 
SSTR2P308743I2D: score=1 
SSTR3P327453I2D: score=1 
SSTR4P313913I2D: score=1 
SSTR5P353463I2D: score=1 
About this table

Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IDA9125122
GO:0007268synaptic transmission NAS9125122

Find genes that share ontologies with CORT           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CORT

1 HMDB Compound for CORT    About this table
CompoundSynonyms CAS #PubMed Ids
Cyclic AMPCyclic AMP (see all 19)60-92-4--

10 Novoseek inferred chemical compound relationships for CORT gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
somatostatin 14 90.2 1 9650799 (1)
vapreotide 84.7 1 15855408 (1)
hexarelin 78.8 3 11227737 (1), 14594107 (1), 11314756 (1)
octreotide 60.6 5 10219983 (1), 10399028 (1), 15094227 (1), 10374816 (1) (see all 5)
acth 44.4 1 17893252 (1)
adenylate 20.4 2 10598790 (1), 15659149 (1)
acetylcholine 11.3 4 10453467 (1), 9205124 (1), 8622767 (1), 11011067 (1)
lysine 0 1 10374816 (1)
glucose 0 1 16625861 (1)
tyrosine 0 1 18951121 (1)



Find genes that share compounds with CORT           About GenesLikeMe



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CORT gene: 
NM_001302.4  

Unigene Cluster for CORT:

Cortistatin
Hs.412311  [show with all ESTs]
Unigene Representative Sequence: NM_001270517
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000377049(uc001ari.3) ENST00000320498
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CORT using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate CORT:
hsa-miR-374c hsa-miR-655
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CORT
Predesigned siRNA for gene silencing in human, mouse, rat CORT
Clone
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OriGene clones in human, mouse for CORT (see all 5)
OriGene ORF clones in mouse, rat for CORT
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CORT (NM_001302)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CORT
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CORT
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for CORT
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CORT
  QuantiTect SYBR Green Assays in human, mouse, rat CORT
  QuantiFast Probe-based Assays in human, mouse, rat CORT

Additional mRNA sequence: 

AB000263.1 AF013252.1 AF086433.1 AY358561.1 BC029430.1 BC040034.1 BC119724.1 BC119725.1 
NR_036462.1 NR_037187.1 

13 DOTS entries:

DT.100813917  DT.443038  DT.314859  DT.100027550  DT.121367698  DT.97808227  DT.100023455  DT.121367683 
DT.75182715  DT.91746558  DT.95260771  DT.95268755  DT.97818062 

Selected AceView cDNA sequences (see all 150):

NM_198544 NM_199294 BQ082222 BM464479 AI364233 AI138905 AW244015 AI083637 
NM_199006 AF516753 AI304921 AI479158 AI287304 CR593315 AI640354 BQ012779 
NM_199295 AI221972 CR593499 NM_001302 AI922894 CA311915 BE551645 BQ010739 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CORT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GTTGACTTTT
CORT Expression
About this image


CORT expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Brain (Nervous System)    fully expand to see all 10 entries
         Cerebral Cortex
         Midbrain   
 
 Smooth Muscle (Muscoskeletal System)
         Juxtaglomerular Cells Afferent Arteriole
 
 Kidney (Urinary System)
         Juxtaglomerular Cells Afferent Arteriole
CORT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CORT Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.412311

UniProtKB/Swiss-Prot: CORT_HUMAN, O00230
Tissue specificity: Expressed in a subset of GABAergic cells in the cortex and hippocampus

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORT

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and mouse.

Orthologs for CORT gene from Selected species (see all 6)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cort1 , 5 cortistatin1, 5 72.35(n)1
59.09(a)1
  4 (78.89 cM)5
128541  NM_007745.31  NP_031771.11 
 1491250345 


ENSEMBL Gene Tree for CORT (if available)
TreeFam Gene Tree for CORT (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CORT:    About this table    
Variant IDTypeSubtypePubMed ID
essv3548CNV CNV17122850
dgv17e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CORT
DNA2.0 Custom Variant and Variant Library Synthesis for CORT

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 602784    OMIM disorders: --

1 disease for CORT:    
About MalaCards
intestinal disease


Find genes that share disorders with CORT           About GenesLikeMe

6 Novoseek inferred disease relationships for CORT gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
prolactinoma 64 3 16449338 (2), 16595604 (1)
autoimmune diseases 18.4 2 20030609 (1), 17080202 (1)
primary tumor 0 2 10894940 (1), 17114908 (1)
inflammation 0 2 19803425 (1), 17150030 (1)
tumors 0 3 18276067 (1), 17114908 (1)
cancer 0 2 19722632 (1), 17114908 (1)

Genetic Association Database (GAD): CORT
Human Genome Epidemiology (HuGE) Navigator: CORT (4 documents)

Export disorders for CORT gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CORT gene, integrated from 10 sources (see all 108):
(articles sorted by number of sources associating them with CORT)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. (PubMed id 9205124)1, 2, 3, 9 de Lecea L.... Sutcliffe J.G. (Genomics 1997)
  2. Identification and characterization of a novel human cortistatin-like peptide. (PubMed id 9125122)1, 2, 9 Fukusumi S.... Fujino M. (Biochem. Biophys. Res. Commun. 1997)
  3. Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)1, 4 Saus E....Estivill X. (J Psychiatr Res 2010)
  4. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  6. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. (PubMed id 11011067)1, 9 Spier A.D. and de Lecea L. (Brain Res. Brain Res. Rev. 2000)
  7. Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3--&gt;p36.2, but absence of mutations in primary tumors. (PubMed id 10894940)1, 9 EjeskAor K....Martinsson T. (Cytogenet. Cell Genet. 2000)
  8. Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and nondiabetic control subjects. (PubMed id 16043736)1, 9 HernA!ndez C....SimA^ R. (Diabetes Care 2005)
  9. Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland. (PubMed id 11227737)1, 9 Deghenghi R....Muccioli G. (J. Endocrinol. Invest. 2001)
  10. Expression of Somatostatin, cortistatin, and their receptors, as well as dopamine receptors, but not of neprilysin, are reduced in the temporal lobe of Alzheimer's disease patients. (PubMed id 20164562)1, 9 Gahete M.D....CastaA+o J.P. (J. Alzheimers Dis. 2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1325 HGNC: 2257 AceView: CORT Ensembl:ENSG00000241563 euGenes: HUgn1325
ECgene: CORT H-InvDB: CORT

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CORT Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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 EMD Millipore genomic analysis products

  
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