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Aliases for CORO7-PAM16 Gene

Aliases for CORO7-PAM16 Gene

  • CORO7-PAM16 Readthrough 2 3 5

External Ids for CORO7-PAM16 Gene

Previous GeneCards Identifiers for CORO7-PAM16 Gene

  • GC16U901294
  • GC16M004392

Summaries for CORO7-PAM16 Gene

Entrez Gene Summary for CORO7-PAM16 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring CORO7 (coronin 7) and PAM16 (presequence translocase-associated motor 16) genes on chromosome 16. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jan 2011]

GeneCards Summary for CORO7-PAM16 Gene

CORO7-PAM16 (CORO7-PAM16 Readthrough) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Mitochondrial protein import. An important paralog of this gene is CORO6.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CORO7-PAM16 Gene

Genomics for CORO7-PAM16 Gene

Genomic Location for CORO7-PAM16 Gene

Chromosome:
16
Start:
4,340,251 bp from pter
End:
4,420,494 bp from pter
Size:
80,244 bases
Orientation:
Minus strand

Genomic View for CORO7-PAM16 Gene

Genes around CORO7-PAM16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CORO7-PAM16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CORO7-PAM16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CORO7-PAM16 Gene

No data available for Regulatory Elements for CORO7-PAM16 Gene

Proteins for CORO7-PAM16 Gene

  • Protein details for CORO7-PAM16 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0A6YYL4
    Recommended name:
    Coronin
    Protein Accession:
    A0A0A6YYL4

    Protein attributes for CORO7-PAM16 Gene

    Size:
    1048 amino acids
    Molecular mass:
    114166 Da
    Quaternary structure:
    No Data Available
  • Protein details for CORO7-PAM16 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    I3L167
    Recommended name:
    Coronin
    Protein Accession:
    I3L167

    Protein attributes for CORO7-PAM16 Gene

    Size:
    535 amino acids
    Molecular mass:
    57677 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CORO7-PAM16 Gene

Proteomics data for CORO7-PAM16 Gene at MOPED

Post-translational modifications for CORO7-PAM16 Gene

No Post-translational modifications

Other Protein References for CORO7-PAM16 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CORO7-PAM16 Gene

Domains & Families for CORO7-PAM16 Gene

Protein Domains for CORO7-PAM16 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CORO7-PAM16: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CORO7-PAM16 Gene

Function for CORO7-PAM16 Gene

Phenotypes for CORO7-PAM16 Gene

GenomeRNAi human phenotypes for CORO7-PAM16:
genes like me logo Genes that share phenotypes with CORO7-PAM16: view

Animal Model Products

miRNA for CORO7-PAM16 Gene

miRTarBase miRNAs that target CORO7-PAM16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CORO7-PAM16 Gene

Localization for CORO7-PAM16 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CORO7-PAM16 Gene COMPARTMENTS Subcellular localization image for CORO7-PAM16 gene
Compartment Confidence
cytosol 5
golgi apparatus 5
mitochondrion 2
nucleus 2
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CORO7-PAM16 Gene

Pathways & Interactions for CORO7-PAM16 Gene

genes like me logo Genes that share pathways with CORO7-PAM16: view

Pathways by source for CORO7-PAM16 Gene

2 Reactome pathways for CORO7-PAM16 Gene

Interacting Proteins for CORO7-PAM16 Gene

Gene Ontology (GO) - Biological Process for CORO7-PAM16 Gene

None

No data available for SIGNOR curated interactions for CORO7-PAM16 Gene

Drugs & Compounds for CORO7-PAM16 Gene

No Compound Related Data Available

Transcripts for CORO7-PAM16 Gene

mRNA/cDNA for CORO7-PAM16 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CORO7-PAM16 Gene

No ASD Table

Relevant External Links for CORO7-PAM16 Gene

GeneLoc Exon Structure for
CORO7-PAM16
ECgene alternative splicing isoforms for
CORO7-PAM16

Expression for CORO7-PAM16 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CORO7-PAM16 Gene

This gene is overexpressed in NK cells (14.8) and Lymph node (11.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb for CORO7-PAM16 Gene



genes like me logo Genes that share expression patterns with CORO7-PAM16: view

Protein tissue co-expression partners for CORO7-PAM16 Gene

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CORO7-PAM16 Gene

Orthologs for CORO7-PAM16 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CORO7-PAM16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CORO7 35
  • 97.06 (n)
  • 96.76 (a)
-- 36
  • 99 (a)
OneToMany
cow
(Bos Taurus)
Mammalia CORO7 36
  • 87 (a)
OneToMany
CORO7 35
  • 86.43 (n)
  • 87.2 (a)
dog
(Canis familiaris)
Mammalia CORO7 35
  • 86.04 (n)
  • 87.09 (a)
-- 36
  • 87 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Coro7 16
Coro7 36
  • 86 (a)
OneToMany
Coro7 35
  • 81.47 (n)
  • 84.8 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 72 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 75 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Coro7 35
  • 80.67 (n)
  • 82.95 (a)
chicken
(Gallus gallus)
Aves CORO7 36
  • 67 (a)
OneToMany
CORO7 35
  • 68.89 (n)
  • 67.58 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 66 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia coro7 35
  • 60.85 (n)
  • 57.24 (a)
zebrafish
(Danio rerio)
Actinopterygii CABZ01076758.1 36
  • 67 (a)
ManyToMany
coro7 36
  • 44 (a)
ManyToMany
coro7 35
  • 61.81 (n)
  • 57.24 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000930 35
  • 43.86 (n)
  • 32.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta pod1 35
  • 51.29 (n)
  • 42.27 (a)
pod1 36
  • 30 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea pod-1 35
  • 45.94 (n)
  • 34.69 (a)
pod-1 36
  • 27 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CRN1 36
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 41 (a)
OneToMany
Species with no ortholog for CORO7-PAM16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CORO7-PAM16 Gene

ENSEMBL:
Gene Tree for CORO7-PAM16 (if available)
TreeFam:
Gene Tree for CORO7-PAM16 (if available)

Paralogs for CORO7-PAM16 Gene

Paralogs for CORO7-PAM16 Gene

(5) SIMAP similar genes for CORO7-PAM16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CORO7-PAM16: view

Variants for CORO7-PAM16 Gene

Sequence variations from dbSNP and Humsavar for CORO7-PAM16 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs7188226 -- 4,353,405(+) cctcc(C/T)gaagt intron-variant
rs114996171 -- 4,353,738(+) CTTCC(C/T)CTTCC intron-variant
rs113570540 -- 4,353,533(+) CACCT(C/T)GGCCT intron-variant
rs138759653 -- 4,353,723(+) TACAC(A/C)GCTGC intron-variant
rs143074830 -- 4,353,645(+) CAAGC(A/G/T)CCTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CORO7-PAM16 Gene

Variant ID Type Subtype PubMed ID
nsv527866 CNV Loss 19592680
nsv905222 CNV Loss 21882294
nsv905223 CNV Loss 21882294
nsv905224 CNV Loss 21882294
dgv2585n71 CNV Loss 21882294
dgv2586n71 CNV Loss 21882294
nsv471075 CNV Loss 18288195
esv23732 CNV Gain 19812545
esv1211300 CNV Insertion 17803354
nsv103783 CNV Loss 16902084
esv1548790 CNV Insertion 17803354
esv2667108 CNV Deletion 23128226
nsv905232 CNV Loss 21882294
esv2659570 CNV Deletion 23128226
nsv905233 CNV Loss 21882294
nsv520212 CNV Loss 19592680
nsv833132 CNV Loss 17160897

Variation tolerance for CORO7-PAM16 Gene

Residual Variation Intolerance Score: 93.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.98; 60.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CORO7-PAM16 Gene

HapMap Linkage Disequilibrium report
CORO7-PAM16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CORO7-PAM16 Gene

Disorders for CORO7-PAM16 Gene

Relevant External Links for CORO7-PAM16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CORO7-PAM16

No disorders were found for CORO7-PAM16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CORO7-PAM16 Gene

Publications for CORO7-PAM16 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CORO7-PAM16 Gene

Sources for CORO7-PAM16 Gene

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