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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CORO7 Gene

protein-coding GIFtS: 51
GCID: GC16M004405

coronin 7

Explore 1 disease affiliated with
CORO7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Coronin 7¹ ²		FLJ22021¹
70 KDa WD Repeat Tumor Rejection Antigen Homolog² ³		0610011B16Rik²
CRN7² ⁵		Coronin-7¹
POD1² ⁵		Crn7³

External Ids:	HGNC: 26161¹	Entrez Gene: 79585²	Ensembl: ENSG00000103426⁷	OMIM: 611668⁵	UniProtKB: P57737³

Export aliases for CORO7 gene to outside databases

Previous GC identifer: GC16M004344

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CORO7:

Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays

a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 (PubMed 15327992) (PubMed

16905771)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: CORO7_HUMAN, P57737

Function: May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CORO7 gene promoter:
AP-1 ATF-2 STAT3 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CORO7 promoter sequence

Search SABiosciences Chromatin IP Primers for CORO7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CORO7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3

CORO7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CORO7 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M004405: view genomic region (about GC identifiers)

Start:	4,390,252 bp from pter	End:	4,470,495 bp from pter
Size:	80,244 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CORO7_HUMAN, P57737 (See protein sequence)

Recommended Name: Coronin-7

Size: 925 amino acids; 100605 Da

Subunit: Interacted with clathrin adapter AP1 complex. This interaction takes place at Golgi membranes and not

AP1-positive endosomal membranes

Subcellular location: Cytoplasm, cytosol (By similarity). Golgi apparatus membrane. Cytoplasmic vesicle (By

similarity). Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not

associated with actin filaments

Secondary accessions: B4DL18 I3L416 Q17RK4

Alternative splicing: 3 isoforms: P57737-1 P57737-2 P57737-3 (No experimental confirmation available. Ref.4 (BC032732) sequence is in conflict in position: 1037:Q->K)

Explore the universe of human proteins at neXtProt for CORO7: NX_P57737

Post-translational modifications:

The membrane-associated form is phosphorylated on tyrosine residues (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P57737

CORO7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001188401.1 NP_001188402.1 NP_078811.3

ENSEMBL proteins:

ENSP00000460885 ENSP00000458607

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	OriGene Purified Protein: CORO7 OriGene Protein Over-expression Lysate: CORO7 OriGene Custom Protein Services for CORO7
	GenScript Custom Purified and Recombinant Proteins Services for CORO7
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CORO7

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0005794	Golgi apparatus	ISS	--
GO:0005829	cytosol	IEA	--
GO:0015629	NOT actin cytoskeleton	IRD	--
GO:0016021	integral to membrane	ISS	--

CORO7 for ontologies About GeneDecksing

CORO7 Antibody Products:

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	Novus Biologicals CORO7 Antibody
	Search for Antibodies for CORO7 at Abcam
	Uscn Antibodies for CORO7
	ThermoFisher Antibodies for CORO7

Assay Products for CORO7:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CORO7
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CORO7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CORO7 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR019775 WD40_repeat_CS

IPR015049 DUF1900

IPR001680 WD40_repeat

IPR020472 G-protein_beta_WD-40_rep

IPR015505 Coronin

Graphical View of Domain Structure for InterPro Entry P57737

ProtoNet protein and cluster: P57737

UniProtKB/Swiss-Prot: CORO7_HUMAN, P57737

Similarity: Belongs to the WD repeat coronin family

Similarity: Contains 8 WD repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CORO7_HUMAN, P57737

Function: May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi

miRNA Products:		OriGene 3'-UTR Clone: CORO7 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CORO7
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate CORO7 (see all 9):
		hsa-miR-31 hsa-miR-125a-5p hsa-miR-3146 hsa-miR-561 hsa-miR-570 hsa-miR-3943 hsa-miR-125b hsa-miR-302f

		SwitchGear 3'UTR luciferase reporter plasmid: CORO7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CORO7 (see all 4) OriGene shRNA RFP: CORO7 OriGene siRNA: CORO7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CORO7

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CORO7

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CORO7 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CORO7 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): CORO7 (NM_024535)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CORO7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CORO7

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CORO7
		Search LifeMap BioReagents cell lines for CORO7

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORO7

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0051015	NOT actin filament binding	IRD	--

CORO7 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for CORO7:

Synthetic lethal with c-Myc af

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CORO7

5/7 Interacting proteins for CORO7 (P57737^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CDC34	P49427²^,³	MINT-8076046 I2D: score=2
CUL1	Q13616²^,³	MINT-8076031 I2D: score=2
RBX1	P62877²^,³	MINT-8076057 I2D: score=2
TCEB1	Q15369²^,³	MINT-8076021 I2D: score=2
TCEB2	Q15370²^,³	MINT-8076005 I2D: score=2

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030036	NOT actin cytoskeleton organization	IRD	--

CORO7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CORO7
Search CenterWatch for drugs/clinical trials and news about CORO7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CORO7 gene (3 alternative transcripts):

NM_001201472.1 NM_001201473.1 NM_024535.4

Unigene Cluster for CORO7:

Coronin 7

Hs.437957 [show with all ESTs]

Unigene Representative Sequence: NM_024535

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000572467 ENST00000575334(uc002cwe.3 uc002cwf.3 uc010uxj.1 uc010btp.1)

ENST00000572274

miRNA Products:		OriGene 3'-UTR Clone: CORO7 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CORO7
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate CORO7 (see all 9):
		hsa-miR-31 hsa-miR-125a-5p hsa-miR-3146 hsa-miR-561 hsa-miR-570 hsa-miR-3943 hsa-miR-125b hsa-miR-302f

		SwitchGear 3'UTR luciferase reporter plasmid: CORO7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CORO7 (see all 4) OriGene shRNA RFP: CORO7 OriGene siRNA: CORO7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CORO7

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CORO7 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CORO7 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): CORO7 (NM_024535)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CORO7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CORO7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CORO7 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat CORO7
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CORO7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CORO7

Additional cDNA sequence:

AK025674.1 AK094596.1 AK294045.1 AK296723.1 AK296807.1 AK309763.1 BC117289.1 BC117291.1

24/28 DOTS entries (see all 28):

DT.100842658 DT.100035681 DT.120686782 DT.100817257 DT.207654 DT.120686838 DT.120686756 DT.100035683

DT.100035684 DT.40107311 DT.449076 DT.101975547 DT.120686747 DT.120686858 DT.75177625 DT.95171805

DT.100704137 DT.102831733 DT.120686778 DT.120686811 DT.120686825 DT.120686843 DT.120686850 DT.91968358

24/277 AceView cDNA sequences (see all 277):

BM710070 BQ011933 AI800826 AI922770 AI801913 AA513366 BE672892 BM450422

NM_016069 AI309908 BX095660 AI424481 AW249037 BM853406 BQ060714 AI865884

NM_024535 AI268592 AK126176 BM469939 BQ882990 CA419484 AK025674 AK094596

GeneLoc Exon Structure

5/21 Alternative Splicing Database (ASD) splice patterns (SP) for CORO7 (see all 21) About this scheme

ExUns:	1	^	2a	·	2b	·	2c	·	2d	·	2e	^	3a	·	3b	·	3c	·	3d	^	4	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9a	·	9b	·	9c	·	9d	·	9e	·	9f	^	10a	·	10b	·	10c	^
SP1:													-		-		-		-		-		-				-
SP2:																					-		-				-														-		-		-
SP3:
SP4:													-		-		-		-		-		-				-												-		-		-		-		-		-		-
SP5:													-		-		-		-		-		-				-														-		-		-

ExUns:	11	^	12a	·	12b	^	13a	·	13b	^	14	^	15	^	16	^	17a	·	17b	^	18a	·	18b	^	19a	·	19b	^	20	^	21	^	22	^	23	^	24	^	25a	·	25b	^	26	^	27	^	28	^	29	^	30a	·
SP1:																					-				-						-		-
SP2:																					-				-						-		-
SP3:																															-		-
SP4:	-		-
SP5:

ExUns:	30b	^	31	^	32a	·	32b	^	33	^	34a	·	34b	·	34c
SP1:							-
SP2:							-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for CORO7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CORO7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCCTGGGCA

About this image

CORO7 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Retina

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CORO7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CORO7

SOURCE GeneReport for Unigene cluster: Hs.437957

SABiosciences Custom PCR Arrays for CORO7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CORO7 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CORO7

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORO7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CORO7 gene from 6/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CORO7¹	coronin 7	69.32(n) 68.38(a)		416670 NM_001006176.1 NP_001006176.1
lizard (Anolis carolinensis)	Reptilia	CORO7⁶	--	64(a)	1 → many	GL343856.1(20367-35832)
African clawed frog (Xenopus laevis)	Amphibia	Xl.6618²	Xenopus laevis transcribed sequence with weak similarity more	74.22(n)		BJ074622.1
zebrafish (Danio rerio)	Actinopterygii	coro7¹	coronin 7	62.24(n) 57.85(a)		569563 NM_001030236.1 NP_001025407.1
fruit fly (Drosophila melanogaster)	Insecta	pod1¹	CG4532-PA	50.04(n) 40.85(a)		31620 NM_132124.5 NP_572352.1
worm (Caenorhabditis elegans)	Secernentea	pod-1¹	Protein POD-1	45.46(n) 34.1(a)		176784 NM_067396.4 NP_499797.1

ENSEMBL Gene Tree for CORO7 (if available)
TreeFam Gene Tree for CORO7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CORO7 gene

CORO7-PAM16 CORO1B² CORO6² CORO1A² CORO1C² CORO2A² CORO2B²

11 SIMAP similar genes for CORO7 using alignment to 20 protein entries: CORO7_HUMAN (see all proteins):

CORO7-PAM16 WSB1 DKFZp762I166 CORO6 CORO1B CORO1C

PF20 CORO2A CORO2B CORO1A POC1B

CORO7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs190524686^1,2		--	4404149(+)	`GTCTTG/TAACTC`	4	--	int¹		0	--	--	--	--
rs113199167^1,2		--	4404187(+)	`GCCTCT/CCAAAG`	4	--	int¹		2		CSA	3
rs12925948^1,2	C,F,	--	4404267(+)	`ATATGC/TTCGTG`	4	--	int¹		9		NA WA EA	548
rs141978433^1,2		--	4404317(+)	`TGAAGA/GTCCTT`	4	--	int¹		0	--	--	--	--
rs150694471^1,2		--	4404406(+)	`ACTCCA/CAGCAG`	4	--	int¹		0	--	--	--	--
rs182403299^1,2		--	4404468(+)	`CCCAGA/GGCCAG`	4	--	int¹		0	--	--	--	--
rs188340780^1,2		--	4404615(+)	`TCACAC/TCCCCC`	4	--	ut3¹ int¹		0	--	--	--	--
rs10974^1,2	C,F,H,	--	4404620(-)	`AATAAG/AGGGGG`	4	--	ut3¹ int¹		19		EA NS NA WA	3816
rs139882114^1,2		--	4404729(+)	`CTGGTA/GGGGGG`	4	--	ut3¹ int¹		0	--	--	--	--
rs192757440^1,2		--	4404756(+)	`TTGACC/GAGAAC`	4	--	ut3¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CORO7 (4390252 - 4470495 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CORO7
1 CNV: 72438

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CORO7

DNA2.0 Custom Variant and Variant Library Synthesis for CORO7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CORO7 for disorders           About GeneDecksing

OMIM gene information: 611668    OMIM disorders: --

1 disease for CORO7:    About MalaCards

malaria

Human Genome Epidemiology (HuGE) Navigator: CORO7 (1 document)

Export disorders for CORO7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CORO7 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with CORO7)

Utopia: connect your pdf to the dynamic
world of online information

Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus. (PubMed id 15327992)^{1, 2, 3} Rybakin V.... Hasse A. (2004)
Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi. (PubMed id 16905771)^{1, 2} Rybakin V....Noegel A.A. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Molecular mechanism underlying the association of Coronin-7 with Golgi membranes. (PubMed id 18581049)^{1, 9} Rybakin V....Clemen C.S. (2008)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob. (PubMed id 21130766)¹ Watanabe M....Yamamoto T. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 79585	HGNC: 26161	AceView: MagmasandCRN7	Ensembl:ENSG00000103426	euGenes: HUgn79585
ECgene: CORO7	H-InvDB: CORO7

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CORO7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CORO7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CORO7 gene:
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GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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