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Aliases for CORO6 Gene

Aliases for CORO6 Gene

  • Coronin 6 2 3
  • Coronin-Like Protein E 3 4
  • Clipin-E 3 4
  • Coronin, Actin Binding Protein 6 3
  • Coronin-6 3

External Ids for CORO6 Gene

Previous GeneCards Identifiers for CORO6 Gene

  • GC17M024965
  • GC17M027941
  • GC17M024151

Summaries for CORO6 Gene

GeneCards Summary for CORO6 Gene

CORO6 (Coronin 6) is a Protein Coding gene. GO annotations related to this gene include actin filament binding. An important paralog of this gene is CORO1A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CORO6 Gene

Genomics for CORO6 Gene

Regulatory Elements for CORO6 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CORO6 Gene

29,614,756 bp from pter
29,622,908 bp from pter
8,153 bases
Minus strand

Genomic View for CORO6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CORO6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CORO6 Gene

Proteins for CORO6 Gene

  • Protein details for CORO6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • B3KU26
    • Q71MF3
    • Q8WYH7
    • Q96K02

    Protein attributes for CORO6 Gene

    472 amino acids
    Molecular mass:
    52762 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG22467.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; Sequence=BAG53288.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CORO6 Gene


neXtProt entry for CORO6 Gene

Proteomics data for CORO6 Gene at MOPED

Post-translational modifications for CORO6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CORO6 Gene

Antibody Products

No data available for DME Specific Peptides for CORO6 Gene

Domains for CORO6 Gene

Gene Families for CORO6 Gene

  • CORO :Coronins
  • WDR :WD repeat domain containing

Suggested Antigen Peptide Sequences for CORO6 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q6QEF8
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with CORO6: view

Function for CORO6 Gene

Gene Ontology (GO) - Molecular Function for CORO6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0051015 actin filament binding IBA --
genes like me logo Genes that share ontologies with CORO6: view

miRNA for CORO6 Gene

miRTarBase miRNAs that target CORO6

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CORO6 Gene

Localization for CORO6 Gene

Subcellular locations from

Jensen Localization Image for CORO6 Gene COMPARTMENTS Subcellular localization image for CORO6 gene
Compartment Confidence
cytoskeleton 3
cytosol 3
mitochondrion 2
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CORO6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015629 actin cytoskeleton IBA --
genes like me logo Genes that share ontologies with CORO6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CORO6 Gene

Pathways for CORO6 Gene

SuperPathways for CORO6 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CORO6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030036 actin cytoskeleton organization IBA --
genes like me logo Genes that share ontologies with CORO6: view

No data available for Pathways by source for CORO6 Gene

Transcripts for CORO6 Gene

Unigene Clusters for CORO6 Gene

Coronin 6:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CORO6

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CORO6 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^
SP1: -
SP2: - - - - - -
SP3: - - -
SP4: - - - -
SP5: -
SP8: - - - - - - - - - - - - - - - -
SP9: - - -
SP10: - - - - - - -
SP11: -

ExUns: 13a · 13b · 13c

Relevant External Links for CORO6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CORO6 Gene

mRNA expression in normal human tissues for CORO6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CORO6 Gene

This gene is overexpressed in Muscle - Skeletal (16.4).

Protein differential expression in normal tissues for CORO6 Gene

This gene is overexpressed in Fetal heart (31.7) and Heart (20.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CORO6 Gene

SOURCE GeneReport for Unigene cluster for CORO6 Gene Hs.143046

genes like me logo Genes that share expressions with CORO6: view

Expression partners for CORO6 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CORO6 Gene

Orthologs for CORO6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CORO6 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia CORO6 35
  • 92.71 (n)
  • 98.3 (a)
CORO6 36
  • 86 (a)
(Mus musculus)
Mammalia Coro6 35
  • 86.77 (n)
  • 93.63 (a)
Coro6 16
Coro6 36
  • 97 (a)
(Pan troglodytes)
Mammalia CORO6 35
  • 99.51 (n)
  • 99.58 (a)
CORO6 36
  • 87 (a)
(Rattus norvegicus)
Mammalia Coro6 35
  • 89.48 (n)
  • 96.4 (a)
(Bos Taurus)
Mammalia CORO6 36
  • 98 (a)
(Monodelphis domestica)
Mammalia CORO6 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia CORO6 36
  • 73 (a)
(Gallus gallus)
Aves CORO6 35
  • 78.63 (n)
  • 80.25 (a)
CORO6 36
  • 79 (a)
(Anolis carolinensis)
Reptilia CORO6 36
  • 81 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia coro6 35
  • 71.7 (n)
  • 80.85 (a)
(Danio rerio)
Actinopterygii coro6 35
  • 73.49 (n)
  • 78.35 (a)
coro6 36
  • 71 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.313 36
  • 43 (a)
Species with no ortholog for CORO6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CORO6 Gene

Gene Tree for CORO6 (if available)
Gene Tree for CORO6 (if available)

Paralogs for CORO6 Gene

Paralogs for CORO6 Gene

Selected SIMAP similar genes for CORO6 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with CORO6: view

Variants for CORO6 Gene

Sequence variations from dbSNP and Humsavar for CORO6 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs871014 -- 29,618,321(-) GCCGG(A/G)TGCCC intron-variant, utr-variant-3-prime, upstream-variant-2KB, utr-variant-5-prime
rs2162660 -- 29,615,271(-) CTGAG(C/T)GGTAA utr-variant-3-prime
rs3029571 -- 29,616,391(-) CTTAG(-/ACAG)GAGAA intron-variant, downstream-variant-500B
rs3744628 -- 29,615,527(+) CAGAC(A/G)AGGCT utr-variant-3-prime
rs3760456 -- 29,621,826(+) ACGGA(C/T)GTGGT upstream-variant-2KB, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CORO6 Gene

Variant ID Type Subtype PubMed ID
nsv833409 CNV Gain 17160897
dgv3135n71 CNV Loss 21882294
nsv908038 CNV Loss 21882294
nsv833410 CNV Loss 17160897

Relevant External Links for CORO6 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CORO6 Gene

Disorders for CORO6 Gene

No disorders were found for CORO6 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CORO6 Gene

Publications for CORO6 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4
  5. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3

Products for CORO6 Gene

Sources for CORO6 Gene

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