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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CORO1B Gene

protein-coding   GIFtS: 52
GCID: GC11M067205

Coronin, Actin Binding Protein, 1B

(Previous names: coronin, actin-binding protein, 1B)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Coronin, Actin Binding Protein, 1B1 2
Coronin, Actin-Binding Protein, 1B1
CORONIN-22
coronin-1B2
Coronin-23

External Ids:    HGNC: 22531   Entrez Gene: 571752   Ensembl: ENSG000001727257   OMIM: 6098495   UniProtKB: Q9BR763   

Export aliases for CORO1B gene to outside databases

Previous GC identifers: GC11P069657 GC11M068901 GC11M067455 GC11M066980 GC11M066962 GC11M063533


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CORO1B Gene:
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell
motility (Cai et al., 2005 (PubMed 16027158)).(supplied by OMIM, Mar 2008)

GeneCards Summary for CORO1B Gene: 
CORO1B (coronin, actin binding protein, 1B) is a protein-coding gene. Diseases associated with CORO1B include coronin-1a deficiency. GO annotations related to this gene include protein binding and actin filament binding. An important paralog of this gene is CORO7-PAM16.

UniProtKB/Swiss-Prot: COR1B_HUMAN, Q9BR76
Function: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and
signal transduction (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CORO1B gene promoter:
         E2F-3a   E2F-4   E2F   E2F-1   Bach2   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCORO1B promoter sequence
   Search SABiosciences Chromatin IP Primers for CORO1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CORO1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.2   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.1

CORO1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CORO1B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M067205:  view genomic region     (about GC identifiers)

Start:
67,205,518 bp from pter      End:
67,211,292 bp from pter
Size:
5,775 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COR1B_HUMAN, Q9BR76 (See protein sequence)
Recommended Name: Coronin-1B  
Size: 489 amino acids; 54235 Da
Subunit: Forms homooligomers, but does not form complexes with the other coronins. Interacts with Arp2/3 complex
components, including ACTR2, ARPC1B and ARPC2. Binds actin (By similarity)
Subcellular location: Cytoplasm, cytoskeleton. Note=Localized to the leading edge in fibroblasts, as well as
weakly along actin stress fibers
Secondary accessions: B2RD45

Explore the universe of human proteins at neXtProt for CORO1B: NX_Q9BR76

Explore proteomics data for CORO1B at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in
    fibroblasts. Phosphorylation does not seem to affect subcellular location
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BR76

  • CORO1B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CORO1B Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001018080.1  NP_065174.1  

    ENSEMBL proteins: 
     ENSP00000340211   ENSP00000445330   ENSP00000416006   ENSP00000438056   ENSP00000377471  

    Human Recombinant Protein Products for CORO1B: 
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    Novus Biologicals CORO1B Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CORO1B 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0015629actin cytoskeleton IBA--

    CORO1B for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing
    CORO: Coronins

    5/8 InterPro protein domains (see all 8):
     IPR019775 WD40_repeat_CS
     IPR015049 DUF1900
     IPR027340 Coro1b
     IPR001680 WD40_repeat
     IPR015505 Coronin

    Graphical View of Domain Structure for InterPro Entry Q9BR76

    ProtoNet protein and cluster: Q9BR76

    UniProtKB/Swiss-Prot: COR1B_HUMAN, Q9BR76
    Similarity: Belongs to the WD repeat coronin family
    Similarity: Contains 5 WD repeats


    CORO1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COR1B_HUMAN, Q9BR76
    Function: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and
    signal transduction (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17350576
    GO:0051015actin filament binding IBA--
         
    CORO1B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CORO1B:
     Decreased focal adhesion (FA)   Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Coro1b):
     immune system 

    CORO1B for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Coro1btm1.1Nfoe for CORO1B

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CORO1B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CORO1B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CORO1B 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CORO1B 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CORO1B
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate CORO1B:
    hsa-miR-3673 hsa-miR-206 hsa-miR-1 hsa-miR-613 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidCORO1B 3' UTR sequence
    Inhib. RNA
    Products:
        
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                         Customized lentivirus expression plasmids for stable overexpression of CORO1B 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORO1B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CORO1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/11 Interacting proteins for CORO1B (Q9BR761, 2, 3 ENSP000003402114) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSH1Q8WYL51, 3, ENSP000003157134EBI-351152,EBI-1222387 I2D: score=2 STRING: ENSP00000315713
    ARPC2O151441, 3, ENSP000002956854EBI-351152,EBI-352356 I2D: score=3 STRING: ENSP00000295685
    ENSG00000258947Q135093I2D: score=1 
    TUBB3Q135093I2D: score=1 
    PRKCAP172523, ENSP000002843844I2D: score=1 STRING: ENSP00000284384
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030036actin cytoskeleton organization IBA--

    CORO1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CORO1B (COR1B)

    Search CenterWatch for drugs/clinical trials and news about CORO1B / COR1B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CORO1B gene (2 alternative transcripts): 
    NM_001018070.2  NM_020441.2  

    Unigene Cluster for CORO1B:

    Coronin, actin binding protein, 1B
    Hs.6191  [show with all ESTs]
    Unigene Representative Sequence: NM_001018070
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000341356(uc001olk.1 uc009yrt.1) ENST00000537042 ENST00000539724
    ENST00000539970 ENST00000453768(uc010rps.1) ENST00000545016(uc009yrv.1)
    ENST00000545736 ENST00000537010 ENST00000393893(uc001oll.2)
    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate CORO1B:
    hsa-miR-3673 hsa-miR-206 hsa-miR-1 hsa-miR-613 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidCORO1B 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for CORO1B
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                         Customized lentivirus expression plasmids for stable overexpression of CORO1B 
    Primer
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    OriGene qPCR primer pairs and template standards for CORO1B
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CORO1B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CORO1B

    Additional mRNA sequence: 

    AK000860.1 AK295782.1 AK315399.1 AL162072.1 BC006449.1 

    16 DOTS entries:

    DT.85105655  DT.91858694  DT.100883104  DT.100806074  DT.100710090  DT.97797305  DT.100831895  DT.100829736 
    DT.120735433  DT.100883094  DT.100883098  DT.95167986  DT.95167975  DT.100659547  DT.95167981  DT.95351542 

    24/629 AceView cDNA sequences (see all 629):

    CD630199 BM848818 BU944577 BI870918 CR591748 AW406570 BM818860 BQ683509 
    BM849025 AI672828 CD673314 AL162072 AL530928 CR612430 BM558555 BQ066636 
    BM818834 BM856605 BQ063906 BM837967 BI834220 BI764261 BU557736 BQ063990 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CORO1B (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ^ 12
    SP1:                                                        -                                               -         
    SP2:              -                                                                                                   
    SP3:              -                                                                                                   
    SP4:                                                                                                                  
    SP5:                                                                                -                                 


    ECgene alternative splicing isoforms for CORO1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CORO1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGAACGGGG
    CORO1B Expression
    About this image


    See CORO1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CORO1B

    SOURCE GeneReport for Unigene cluster: Hs.6191
        SABiosciences Custom PCR Arrays for CORO1B
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CORO1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CORO1B gene from 7/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Coro1b1 , 5 coronin, actin binding protein 1B1, 5 87.3(n)1
    95.24(a)1
      19 (3.85 cM)5
    237891  NM_011778.21  NP_035908.11 
     41486195 
    chicken
    (Gallus gallus)
    Aves gga-mir-6579-26
    gga-mir-6579-2
    84(a)
    1 ↔ 1
    5(507411-517159)
    lizard
    (Anolis carolinensis)
    Reptilia CORO1B6
    Coronin
    81(a)
    1 ↔ 1
    1(93322652-93355399)
    zebrafish
    (Danio rerio)
    Actinopterygii coro1b6
    coronin, actin binding protein, 1B
    60(a)
    possible ortholog
    7(19832691-19870773)
    fruit fly
    (Drosophila melanogaster)
    Insecta coro3 actin binding 54(a)   42D4   --
    worm
    (Caenorhabditis elegans)
    Secernentea cor-13 Coronin (beta transducin) 52(a)   III(10320798-10326235)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CRN16
    Coronin, cortical actin cytoskeletal component tha...
    27(a)
    1 → many
    XII(990777-992732)


    ENSEMBL Gene Tree for CORO1B (if available)
    TreeFam Gene Tree for CORO1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CORO1B gene
    CORO7-PAM162  CORO1A2  CORO62  CORO72  CORO1C2  CORO2B2  CORO2A2  
    9 SIMAP similar genes for CORO1B using alignment to 4 protein entries:     COR1B_HUMAN (see all proteins):
    DKFZp762I166    CORO1C    CORO1A    CORO6    CORO2B    CORO2A
    CORO7    POC1B    CORO7-PAM16

    CORO1B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/182 SNPs in CORO1B are shown (see all 182)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358774
    A colorectal cancer sample4--see VAR_0358772 V M mis40--------
    VAR_0533894
    ----see VAR_0533892 R L mis40--------
    rs578663821,2
    C--67207197(+) GTCACA/CACTGC 2 -- int14Minor allele frequency- C:0.06NA WA EA 360
    rs1442734201,2
    C--67207209(+) TGGCCC/TGCTTG 2 -- int10--------
    rs1995239511,2
    --67207237(+) TGAGCC/TGAGGG 2 -- int10--------
    rs1130316171,2
    C--67207255(+) GCCTCA/G/TCCTTT 2 -- spd11CSA 1
    rs1117526381,2
    C--67207256(+) CCTCAA/C/GCTTTC 2 -- spd11CSA 1
    rs1999827911,2
    C--67207277(+) CATGAC/TGATGG 4 I V mis10--------
    rs1123271981,2
    C--67207316(+) GAACCG/TGGGGA 2 -- spa10--------
    rs2020035751,2
    --67207317(+) AACCTA/GGGGAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for CORO1B (67205518 - 67211292 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CORO1B:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv468604CNV Loss19166990
    nsv527056CNV Loss19592680
    nsv897797CNV Loss21882294
    nsv521723CNV Loss19592680
    nsv897811CNV Loss21882294
    dgv1194n71CNV Loss21882294
    nsv524096CNV Loss19592680
    dgv1193n71CNV Loss21882294
    nsv897801CNV Loss21882294
    nsv897804CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609849    OMIM disorders: --

    2 diseases for CORO1B:    About MalaCards
    coronin-1a deficiency    

    1 disease from the University of Copenhagen DISEASES database for CORO1B:
    coronin-1A deficiency

    CORO1B for disorders           About GeneDecksing


    Export disorders for CORO1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CORO1B gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with CORO1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility. (PubMed id 16027158)1, 2, 9 Cai L.... Bear J.E. (2005)
    2. Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. (PubMed id 9778037)1, 3, 9 Okumura M....Thomas M.L. (1998)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. (PubMed id 17350576)1, 9 Cai L....Bear J.E. (2007)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. Novel mechanism for negatively regulating Rho-kinase ( ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility. (PubMed id 22563075)1 Rana M.K. and Worthylake R.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57175 HGNC: 2253 AceView: PTPRCAPandCORO1B Ensembl:ENSG00000172725 euGenes: HUgn57175
    ECgene: CORO1B H-InvDB: CORO1B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CORO1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CORO1B gene:
    Search GeneIP for patents involving CORO1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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