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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CORO1A Gene

protein-coding   GIFtS: 59
GCID: GC16P030194

coronin, actin binding protein, 1A

(Previous names: coronin, actin-binding protein, 1A )
 Explore 14 diseases affiliated with
CORO1A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CORO1A    

Aliases
for CORO1A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Coronin, Actin Binding Protein, 1A1 2     CLIPINA2 5
TACO2 3 5     Coronin, Actin-Binding Protein, 1A1
HCORO11 2     CLABP2
Coronin-11     Clipin-A3
P571     Coronin-1A1
Coronin-Like Protein A2 3     CORO13
Coronin-Like Protein P572 3     Clipin-A3
Tryptophan Aspartate-Containing Coat Protein2 3     

External Ids:    HGNC: 22521   Entrez Gene: 111512   Ensembl: ENSG000001028797   OMIM: 6050005   UniProtKB: P311463   

Export aliases for CORO1A gene to outside databases

Previous GC identifers: GC16M028961 GC16P030516 GC16P030193 GC16P030231 GC16P030103 GC16P027857


Summaries
for CORO1A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CORO1A:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or
multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle
progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript
variants. A related pseudogene has been defined on chromosome 16. (provided by RefSeq, Sep 2010)

UniProtKB/Swiss-Prot: COR1A_HUMAN, P31146
Function: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination
of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell
locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between
phagosomes and lysosomes

Gene Wiki entry for CORO1A


Genomic Views
for CORO1A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CORO1A gene promoter:
         CREB   deltaCREB   p300   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CORO1A promoter sequence
   Search SABiosciences Chromatin IP Primers for CORO1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CORO1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

CORO1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CORO1A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P030194:  view genomic region     (about GC identifiers)

Start:
 30,194,148 bp from pter      End:
 30,200,397 bp from pter
Size:
 6,250 bases      Orientation:
 plus strand

Proteins
for CORO1A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: COR1A_HUMAN, P31146 (See protein sequence)
Recommended Name: Coronin-1A  
Size: 461 amino acids; 51026 Da
Subunit: Binds actin (By similarity)
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cell cortex (By similarity). Cytoplasmic
vesicle, phagosome membrane (By similarity). Note=In non-infected macrophages, associated with the cortical
microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the
mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and
not due to impaired acidification (By similarity)
Secondary accessions: B2RBL1 Q2YD73

Explore the universe of human proteins at neXtProt for CORO1A: NX_P31146

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P31146

    • CORO1A Protein expression data from MOPED and PaxDb:    About this image 
    CORO1A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001180262.1  NP_009005.1  

    ENSEMBL proteins: 
     ENSP00000456266   ENSP00000456756   ENSP00000219150   ENSP00000455552   ENSP00000456457  
     ENSP00000457332   ENSP00000454752   ENSP00000457509  

    Human Recombinant Protein Products for CORO1A: 
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    Uscn Proteins for CORO1A

    Gene Ontology (GO): 5/13 cellular component terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001772immunological synapse IEA--
    GO:0001891phagocytic cup IDA17442961
    GO:0005634NOT nucleus IDA17341475
    GO:0005737cytoplasm IDA17341475
    GO:0005884actin filament IDA15800061

    CORO1A for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CORO1A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CORO1A for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR019775 WD40_repeat_CS
     IPR015049 DUF1900
     IPR001680 WD40_repeat
     IPR015505 Coronin
     IPR017986 WD40_repeat_dom

    Graphical View of Domain Structure for InterPro Entry P31146

    ProtoNet protein and cluster: P31146

    UniProtKB/Swiss-Prot: COR1A_HUMAN, P31146
    Similarity: Belongs to the WD repeat coronin family
    Similarity: Contains 7 WD repeats


    Function
    for CORO1A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COR1A_HUMAN, P31146
    Function: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination
    of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell
    locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between
    phagosomes and lysosomes

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008022protein C-terminus binding IPI9365277
    GO:0008092cytoskeletal protein binding ISS--
    GO:0042802identical protein binding ----
    GO:0042803protein homodimerization activity IDA15601263
         
    CORO1A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CORO1A:
     Decreased focal adhesion (FA)  

         4 MGI mutant phenotypes (inferred from 6 alleles) (MGI details for Coro1a):
     cellular  hematopoietic system  immune system  renal/urinary system 

    CORO1A for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Coro1atm1Achn for CORO1A
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CORO1A 

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for CORO1A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Tuberculosis
    		Tuberculosis1.00
    2Phagosome
    		Phagosome1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    2         Kegg Pathways  (Kegg details for CORO1A):
        Phagosome
    Tuberculosis


    CORO1A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CORO1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/64 Interacting proteins for CORO1A (P311461, 3 ENSP000002191504) via UniProtKB, MINT, STRING, and/or I2D (see all 64)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTBP607093, ENSP000003499604I2D: score=2 STRING: ENSP00000349960
    DKK1O949073, ENSP000003630814I2D: score=2 STRING: ENSP00000363081
    UBE2G2P606043, ENSP000003383484I2D: score=2 STRING: ENSP00000338348
    THBS1P079963, ENSP000002603564I2D: score=2 STRING: ENSP00000260356
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/22 biological process terms (GO ID links to tree view) (see all 22):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001845phagolysosome assembly IMP12132654
    GO:0006816calcium ion transport IEA--
    GO:0006909phagocytosis IMP17442961
    GO:0006928cellular component movement NAS17341475
    GO:0007015actin filament organization IEA--

    CORO1A for ontologies           About GeneDecksing



    Drugs & Compounds
    for CORO1A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CORO1A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for CORO1A
    2 Novoseek chemical compound relationships for CORO1A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 37.8 6 15601263 (3), 7758584 (2)
    nadph 28.1 1 19454722 (1)

    Search CenterWatch for drugs/clinical trials and news about CORO1A / COR1A 

    Transcripts
    for CORO1A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CORO1A gene (2 alternative transcripts): 
    NM_001193333.2  NM_007074.3  

    Unigene Cluster for CORO1A:

    Coronin, actin binding protein, 1A
    Hs.415067  [show with all ESTs]
    Unigene Representative Sequence: AB209221
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563778 ENST00000561815 ENST00000219150(uc010vej.2 uc010bzq.3 uc002dww.3)
    ENST00000564446 ENST00000568763(uc002dwx.3) ENST00000566619 ENST00000568982
    ENST00000570045 ENST00000569469 ENST00000565497 ENST00000570244 ENST00000569203
    ENST00000561849 ENST00000569970 ENST00000567034 ENST00000564768(uc002dwy.1)
    ENST00000562129

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CORO1A (see all 7)
    OriGene siRNA: CORO1A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CORO1A
    Sirion Biotech Custom design and validation of potent shRNA sequences against CORO1A 
    Clone
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    Primer
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    Additional cDNA sequence: 

    AB209221.1 AF495470.1 AK096332.1 AK097964.1 AK296207.1 AK314714.1 BC110374.1 BC126385.1 
    BC126387.1 D44497.1 GQ214031.1 U34690.1 X89109.1 

    24/30 DOTS entries (see all 30):

    DT.217513  DT.100670910  DT.100670905  DT.95099643  DT.95099640  DT.100670901  DT.91771416  DT.217515 
    DT.100670894  DT.120696984  DT.87015760  DT.101984658  DT.120697299  DT.70104382  DT.100656266  DT.92417158 
    DT.100670885  DT.120695588  DT.120696026  DT.120696748  DT.120697637  DT.120698053  DT.100640781  DT.100858855 

    24/696 AceView cDNA sequences (see all 696):

    T35985 CR593972 AI279136 BG755112 CR611130 CR593420 CR620817 BE349210 
    BX458896 X89109 BM918345 BG757036 BQ063788 BM800113 BQ691635 CR618140 
    BQ050407 BG756515 AI279539 CR614308 BF974377 BQ446336 BM454227 AI799562 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for CORO1A (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c · 8d · 8e ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^
    SP1:        -     -     -     -     -           -     -                                                                                                         
    SP2:                                                                                                                                                  -         
    SP3:                                                                                                                                                  -         
    SP4:                                -           -     -                                                                                                         
    SP5:                                                                                                                                                  -         

    ExUns: 13 ^ 14a · 14b ^ 15
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for CORO1A

    Expression
    for CORO1A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CORO1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCAGAGAAAA
    CORO1A Expression
    About this image

    CORO1A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Extraembryonic MesodermExtraembryonic Capillary PlexusExtraembryonic AngioblastsEndothelium
    EyeInner Nuclear LayerGABAergic Amacrine CellsAmacrine, Retina
    LimbForelimb MyotomeLimb Muscle Progenitor CellsSkeletal Muscle
    Skeletal MuscleHyoid Arch MusclesMononuclear MyocytesSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMononuclear MyocytesSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CORO1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CORO1A

    SOURCE GeneReport for Unigene cluster: Hs.415067

    UniProtKB/Swiss-Prot: COR1A_HUMAN, P31146
    Tissue specificity: Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut

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    In Situ
    Assay Products:     
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    Orthologs
    for CORO1A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CORO1A gene from 5/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia CORO1A6
    --
    		 --
    		 66(a)
    31(a)
    		 1 ↔ 1
    possible ortholog
    		 GL343279.1(434271-444188)
    GL344890.1(1981-18509)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC690772 hypothetical protein MGC69077 78.7(n)    BC060754.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc637662 similar to coronin, actin binding protein, 1A 77.95(n)   394089  BC055237.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta coro3 actin binding 57(a)   42D4   --
    worm
    (Caenorhabditis elegans)    		 Secernentea cor-13 Coronin (beta transducin) 51(a)   III(10320798-10326235)   --


    ENSEMBL Gene Tree for CORO1A (if available)
    TreeFam Gene Tree for CORO1A (if available) 

    Paralogs
    for CORO1A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CORO1A gene
    CORO1B2  CORO62  CORO72  CORO1C2  CORO2A2  CORO2B2  
    8 SIMAP similar genes for CORO1A using alignment to 7 protein entries:     COR1A_HUMAN (see all proteins):
    DKFZp762I166    CORO1C    CORO1B    CORO6    CORO2A    CORO2B
    CORO7    CORO7-PAM16

    CORO1A for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CORO1A
    PGOHUM00000262324


    Genomic Variants
    for CORO1A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/119 NCBI SNPs in CORO1A are shown (see all 119)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs798658731,2
    		F--27856265(+) TTTTTA/GAAATG 2 -- us2k11Minor allele frequency- G:0.03WA 118
    rs795125051,2
    		C,F--27856972(+) NNNNGG/CCACGA 2 -- us2k11Minor allele frequency- C:0.14NA 120
    rs9303921,2
    		--27857484(-) CGGGCC/TCCCGC 2 -- ut517Minor allele frequency- T:0.33MN EA NA CSA WA 599
    rs115553401,2
    		C--27857658(+) CCGGCC/TTTTGG 2 -- ut510--------
    rs1163073331,2
    		C,F--27858178(+) GGGCTC/TCCCTC 2 -- int11Minor allele frequency- T:0.04WA 118
    rs727912481,2
    		C,F--27858435(+) CCTTGC/TTCCCC 2 -- int11Minor allele frequency- T:0.20NA 120
    rs784667131,2
    		--27858558(+) TTTTCT/CGAGCG 2 -- int12Minor allele frequency- C:0.08CSA WA 120
    rs790626031,2
    		C--27859293(+) CTTCTG/TTGCTG 4 C F mis10--------
    rs10535741,2
    		F--27862870(+) AGGCCA/CCGGTG 6 T A S mis1 ese31Minor allele frequency- C:0.02MN 184
    rs713894501,2
    		C--27863206(+) AAACCG/AGCCAT 2 -- ds50012Minor allele frequency- A:0.25NA 4

    HapMap Linkage Disequilibrium report for CORO1A (30194148 - 30200397 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for CORO1A
         7 CNVs: 30778 72527 88064 35383 72525 4001 72526
    Human Gene Mutation Database (HGMD): CORO1A

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CORO1A
    DNA2.0 Custom Variant and Variant Library Synthesis for CORO1A

    Disorders / Diseases
    for CORO1A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CORO1A for disorders           About GeneDecksing

    OMIM gene information: 605000    OMIM disorders: --

    14 diseases for CORO1A:    About MalaCards
    attention deficit hyperactivity disorder    severe combined immunodeficiency    primary effusion lymphoma    combined immunodeficiency
    chronic granulomatous disease    astigmatism    cystic fibrosis    pulmonary tuberculosis
    adhd    immunodeficiency    fibrosis    endometriosis
    tuberculosis    malaria


    Export disorders for CORO1A gene to outside databases

    Publications
    for CORO1A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CORO1A gene, integrated from 9 sources (see all 58):
    (articles sorted by number of sources associating them with CORO1A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif. (PubMed id 7758584)1, 2, 9 Suzuki K....Toyoshima S. (1995)
    2. Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. (PubMed id 9778037)1, 3, 9 Okumura M....Thomas M.L. (1998)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A coat protein on phagosomes involved in the intracellular survival of mycobacteria. (PubMed id 10338208)1, 2 Ferrari G.... Pieters J. (1999)
    6. Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)1, 2 Rasmussen H.H....Vandekerckhove J. (1992)
    7. Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients. (PubMed id 19454722)1, 9 Moriceau S....Witko-Sarsat V. (2009)
    8. Phorbol ester-dependent phosphorylation regulates the association of p57/coronin-1 with the actin cytoskeleton. (PubMed id 18693254)1, 9 Oku T....Tsuji T. (2008)
    9. Homotypic dimerization of the actin-binding protein p57/coronin-1 mediated by a leucine zipper motif in the C-terminal region. (PubMed id 15601263)1, 9 Oku T....Tsuji T. (2005)
    10. Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. (PubMed id 17341475)1, 9 Ahmed Z....Dickson D.W. (2007)

    External Searches for CORO1A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CORO1A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11151 HGNC: 2252 AceView: CORO1A Ensembl:ENSG00000102879 euGenes: HUgn11151
    ECgene: CORO1A Kegg: 11151 H-InvDB: CORO1A

    Other Databases showing CORO1A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CORO1A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CORO1A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CORO1A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CORO1A gene:
    Search GeneIP for patents involving CORO1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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