Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COQ10B Gene

protein-coding   GIFtS: 45
GCID: GC02P198318

Coenzyme Q10 Homolog B (S. Cerevisiae)

(Previous name: coenzyme Q10 homolog B (yeast))
  Search for COQ10B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Coenzyme Q10 Homolog B (S. Cerevisiae)1 2
Coenzyme Q10 Homolog B (Yeast)1
Coenzyme Q-Binding Protein COQ10 Homolog B, Mitochondrial2

External Ids:    HGNC: 258191   Entrez Gene: 802192   Ensembl: ENSG000001155207   UniProtKB: Q9H8M13   

Export aliases for COQ10B gene to outside databases

Previous GC identifers: GC02P198144 GC02P198026 GC02P190170


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for COQ10B Gene: 
COQ10B (coenzyme Q10 homolog B (S. cerevisiae)) is a protein-coding gene. An important paralog of this gene is COQ10A.

UniProtKB/Swiss-Prot: CQ10B_HUMAN, Q9H8M1
Function: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be
involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COQ10B gene promoter:
         STAT1   AML1a   STAT4   Brachyury   Bach2   STAT1beta   STAT1alpha   CREB   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOQ10B promoter sequence
   Search SABiosciences Chromatin IP Primers for COQ10B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COQ10B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.1   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33.1

COQ10B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COQ10B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P198318:  view genomic region     (about GC identifiers)

Start:
198,318,147 bp from pter      End:
198,340,032 bp from pter
Size:
21,886 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CQ10B_HUMAN, Q9H8M1 (See protein sequence)
Recommended Name: Coenzyme Q-binding protein COQ10 homolog B, mitochondrial precursor  
Size: 238 amino acids; 27071 Da
Subunit: Interacts with coenzyme Q (By similarity)
Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (By similarity)

Explore the universe of human proteins at neXtProt for COQ10B: NX_Q9H8M1

Explore proteomics data for COQ10B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H8M1

  • COQ10B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COQ10B Protein Expression
    REFSEQ proteins: NP_079423.1  
    ENSEMBL proteins: 
     ENSP00000263960   ENSP00000386785   ENSP00000387223   ENSP00000442520  

    Human Recombinant Protein Products for COQ10B: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for COQ10B
    OriGene Protein Over-expression Lysate for COQ10B
    OriGene MassSpec for COQ10B 
    OriGene Custom Protein Services for COQ10B
    GenScript Custom Purified and Recombinant Proteins Services for COQ10B
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for COQ10B 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--

    COQ10B for ontologies           About GeneDecksing



    COQ10B Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for COQ10B
    GenScript Custom Superior Antibodies Services for COQ10B
    Novus Biologicals COQ10B Antibody
    Abcam antibodies for COQ10B
    Cloud-Clone Corp. Antibodies for COQ10B 
    Search ThermoFisher Antibodies for COQ10B
    Search LSBio for Antibodies for COQ10B 

    Assay Products for COQ10B: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for COQ10B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for COQ10B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for COQ10B 
    Cloud-Clone Corp. CLIAs for COQ10B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR005031 Polyket_cyc
     IPR023393 START-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9H8M1

    ProtoNet protein and cluster: Q9H8M1

    UniProtKB/Swiss-Prot: CQ10B_HUMAN, Q9H8M1
    Similarity: Belongs to the COQ10 family


    COQ10B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CQ10B_HUMAN, Q9H8M1
    Function: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be
    involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes
    (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for COQ10B:

     Increased homologous recombina 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for COQ10B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COQ10B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COQ10B 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COQ10B 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COQ10B
    8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate COQ10B (see all 30):
    hsa-miR-562 hsa-miR-520d-5p hsa-miR-657 hsa-miR-606 hsa-miR-378b hsa-miR-1276 hsa-miR-7-1* hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidCOQ10B 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for COQ10B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COQ10B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for COQ10B
    Sirion Biotech Customized adenovirus for overexpression of COQ10B

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for COQ10B (see all 9)
    OriGene ORF clones in mouse, rat for COQ10B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: COQ10B (NM_025147)
    Sino Biological Human cDNA Clone for COQ10B
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COQ10B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COQ10B
    Sirion Biotech Customized lentivirus for stable overexpression of COQ10B 
                         Customized lentivirus expression plasmids for stable overexpression of COQ10B 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for COQ10B
    Search LifeMap BioReagents cell lines for COQ10B
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COQ10B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COQ10B

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for COQ10B (ENSP000002639604) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COQ10B (CQ10B)

    Search CenterWatch for drugs/clinical trials and news about COQ10B / CQ10B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COQ10B gene: 
    NM_025147.3  

    Unigene Cluster for COQ10B:

    Coenzyme Q10 homolog B (S. cerevisiae)
    Hs.606592  [show with all ESTs]
    Unigene Representative Sequence: AK096309
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263960(uc002uuh.1 uc010fsl.1) ENST00000409398 ENST00000488445
    ENST00000409010 ENST00000545340
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COQ10B
    8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate COQ10B (see all 30):
    hsa-miR-562 hsa-miR-520d-5p hsa-miR-657 hsa-miR-606 hsa-miR-378b hsa-miR-1276 hsa-miR-7-1* hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidCOQ10B 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for COQ10B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COQ10B
    Clone
    Products:
         
    OriGene clones in human, mouse for COQ10B (see all 9)
    OriGene ORF clones in mouse, rat for COQ10B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: COQ10B (NM_025147)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COQ10B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COQ10B
    Sirion Biotech Customized lentivirus for stable overexpression of COQ10B 
                         Customized lentivirus expression plasmids for stable overexpression of COQ10B 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for COQ10B
    OriGene qSTAR qPCR primer pairs in human, mouse for COQ10B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COQ10B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COQ10B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COQ10B

    Additional mRNA sequence: 

    AK023510.1 AK096309.1 AK294093.1 AK308977.1 BC022453.1 

    4 DOTS entries:

    DT.95375605  DT.97842333  DT.75119073  DT.100024460 

    24/99 AceView cDNA sequences (see all 99):

    AA232326 BQ010248 BM479944 NM_025147 AK096309 BM769921 BU521741 BM818285 
    AI948661 BU517346 BP343774 BM744220 AI610678 AA339812 AV660489 BI835671 
    BP375243 BU782617 BC022453 AW613728 BX422948 AI818421 BU195968 BI548346 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for COQ10B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b
    SP1:                    -                                             
    SP2:                    -     -     -                                 
    SP3:                    -           -                                 
    SP4:                                                                  


    ECgene alternative splicing isoforms for COQ10B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COQ10B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTCTTCTGA
    COQ10B Expression
    About this image


    See COQ10B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COQ10B

    SOURCE GeneReport for Unigene cluster: Hs.606592
        SABiosciences Custom PCR Arrays for COQ10B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for COQ10B
    OriGene qSTAR qPCR primer pairs in human, mouse for COQ10B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COQ10B
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COQ10B
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COQ10B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COQ10B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for COQ10B gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Coq10b1 , 5 coenzyme Q10 homolog B (S. cerevisiae)1, 5 83.61(n)1
    84.87(a)1
      1 (28.00 cM)5
    678761  NM_001039710.11  NP_001034799.11 
     550527705 
    chicken
    (Gallus gallus)
    Aves COQ10B1 coenzyme Q10 homolog B (S. cerevisiae) 73.94(n)
    76.42(a)
      424057  XM_421913.3  XP_421913.1 
    lizard
    (Anolis carolinensis)
    Reptilia COQ10B6
    --
    Uncharacterized protein
    78(a)
    41(a)
    1 ↔ 1
    possible ortholog
    GL343436.1(710088-714514)
    6(72956736-72966418)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.149652 Xenopus laevis transcribed sequence with moderate similarity more 75.54(n)    BU914274.1 
    zebrafish
    (Danio rerio)
    Actinopterygii coq10b1 coenzyme Q10 homolog B (S. cerevisiae) 64.22(n)
    70.69(a)
      550442  NM_001017747.1  NP_001017747.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG159081 CG15908 49.44(n)
    52.35(a)
      35567  NM_165481.4  NP_724484.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R144.136
    Protein R144.13
    45(a)
    1 → many
    III(5023321-5024067)


    ENSEMBL Gene Tree for COQ10B (if available)
    TreeFam Gene Tree for COQ10B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COQ10B gene
    COQ10A2  
    1 SIMAP similar gene for COQ10B using alignment to 4 protein entries:     CQ10B_HUMAN (see all proteins):
    COQ10A

    COQ10B for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for COQ10B
    PGOHUM00000238373 PGOHUM00000235300


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/463 SNPs in COQ10B are shown (see all 463)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs352611911,2
    C--198316250(+) TCACA-/AGTGAG 1 -- us2k11Minor allele frequency- A:0.00CSA 2
    rs119021951,2
    C,F,H--198316370(+) CAGAAC/GCACCT 1 -- us2k111Minor allele frequency- G:0.38NS EA NA WA 784
    rs1896285151,2
    --198316379(+) CTCAAG/TCTACA 1 -- us2k10--------
    rs1807008481,2
    --198316389(+) AAGTAC/TATCAT 1 -- us2k10--------
    rs1860542021,2
    --198316442(+) TTTCAA/GTGTAT 1 -- us2k10--------
    rs1138387891,2
    C--198316784(+) TTTTC-/TTTTTT 1 -- us2k11Minor allele frequency- T:0.00CSA 2
    rs577248271,2
    C--198316789(+) TTTTTC/TCTTTT 1 -- us2k11Minor allele frequency- T:0.00WA 2
    rs133924861,2
    C--198316795(+) cttttC/Tttttt 1 -- us2k1 trp30--------
    rs102090991,2
    C,F,H--198317184(+) accacC/Tctata 1 -- us2k16Minor allele frequency- T:0.02NS NA WA 910
    rs1154252291,2
    F--198317299(+) GGTTTC/TTTTCC 1 -- us2k11Minor allele frequency- T:0.02WA 118

    HapMap Linkage Disequilibrium report for COQ10B (198318147 - 198340032 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for COQ10B: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing COQ10B
    DNA2.0 Custom Variant and Variant Library Synthesis for COQ10B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    COQ10B for disorders           About MalaCards

    COQ10B for disorders           About GeneDecksing

    Genetic Association Database (GAD): COQ10B
    Human Genome Epidemiology (HuGE) Navigator: COQ10B (1 document)

    Export disorders for COQ10B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COQ10B gene integrated from 9 sources:
    (articles sorted by number of sources associating them with COQ10B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80219 HGNC: 25819 AceView: FLJ13448 Ensembl:ENSG00000115520 euGenes: HUgn80219
    ECgene: COQ10B H-InvDB: COQ10B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COQ10B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COQ10B gene:
    Search GeneIP for patents involving COQ10B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for COQ10B  
     OriGene qPCR primer pairs and template standards for COQ10B   OriGene Protein Over-expression Lysate for COQ10B  
     OriGene MassSpec something-or-other for COQ10B   OriGene clones in human, mouse for COQ10B  
     OriGene qSTAR qPCR primer pairs in human, mouse for COQ10B   OriGene Purified Protein for COQ10B  
     OriGene ORF clones in mouse, rat for COQ10B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for COQ10B   OriGene Custom Protein Services for COQ10B  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COQ10B
     QIAGEN SeqTarget long-range PCR primers for resequencing COQ10B
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COQ10B
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COQ10B
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COQ10B
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COQ10B
     GenScript Custom Purified and Recombinant Proteins Services for COQ10B GenScript cDNA clones with any tag delivered in your preferred vector for COQ10B
     GenScript Custom Assay Services for COQ10B GenScript Custom Superior Antibodies Services for COQ10B
     GenScript Custom overexpressing Cell Line Services for COQ10B CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in COQ10B promoter
     Search Chromatin IP Primers for COQ10B
     RT2 qPCR Primer Assay in human, mouse, rat COQ10B
     Search GNC Networks for COQ10B
     SABiosciences Custom PCR Arrays for COQ10B
     Search Tocris compounds for COQ10B (CQ10B)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for COQ10B
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     COQ10B antibodies
     Antibodies for COQ10B
     See all of Abcam's Antibodies, Kits and Proteins for COQ10B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for COQ10B
     Antibodies for COQ10B
     ELISAs for COQ10B
     CLIAs for COQ10B
     Search LifeMap BioReagents cell lines for COQ10B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COQ10B
     SwitchGear 3'UTR luciferase reporter plasmids for COQ10B
     SwitchGear Promoter luciferase reporter plasmids for COQ10B
     Search ThermoFisher Antibodies for COQ10B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COQ10B
     inGenious Targeting Laboratory - Custom generated mouse model solutions for COQ10B
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COQ10B
    Customized:
     lentivirus for stable overexpression of COQ10B
     lentivirus expression plasmids for stable overexpression of COQ10B
     adenovirus for overexpression of COQ10B
     Search LSBio for Antibodies for COQ10B
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      COQ10B gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4