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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COQ10A Gene

protein-coding   GIFtS: 45
GCID: GC12P056660

Coenzyme Q10 Homolog A (S. Cerevisiae)

(Previous name: coenzyme Q10 homolog A (yeast))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Coenzyme Q10 Homolog A (S. Cerevisiae)1 2
Coenzyme Q10 Homolog A (Yeast)1
Coenzyme Q-Binding Protein COQ10 Homolog A, Mitochondrial2

External Ids:    HGNC: 265151   Entrez Gene: 930582   Ensembl: ENSG000001354697   UniProtKB: Q96MF63   

Export aliases for COQ10A gene to outside databases

Previous GC identifers: GC12P054947 GC12P053700


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for COQ10A Gene: 
COQ10A (coenzyme Q10 homolog A (S. cerevisiae)) is a protein-coding gene. Diseases associated with COQ10A include familial hypercholesterolemia, and hypercholesterolemia. An important paralog of this gene is COQ10B.

UniProtKB/Swiss-Prot: CQ10A_HUMAN, Q96MF6
Function: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be
involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes
(Probable)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COQ10A gene promoter:
         ER-alpha   TBP   GR   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOQ10A promoter sequence
   Search SABiosciences Chromatin IP Primers for COQ10A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COQ10A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13.3

COQ10A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COQ10A gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P056660:  view genomic region     (about GC identifiers)

Start:
56,660,642 bp from pter      End:
56,664,750 bp from pter
Size:
4,109 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CQ10A_HUMAN, Q96MF6 (See protein sequence)
Recommended Name: Coenzyme Q-binding protein COQ10 homolog A, mitochondrial precursor  
Size: 247 amino acids; 27686 Da
Subunit: Interacts with coenzyme Q (By similarity)
Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (By similarity)
Sequence caution: Sequence=AAH26922.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAQ89220.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6GMR6 Q6UWB9 Q86X16 Q8TAL2 Q96MF1 Q9BUP4
Alternative splicing: 3 isoforms:  Q96MF6-1   Q96MF6-2   Q96MF6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COQ10A: NX_Q96MF6

Explore proteomics data for COQ10A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96MF6

  • COQ10A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COQ10A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001092807.1  NP_653177.3  

    ENSEMBL proteins: 
     ENSP00000312587   ENSP00000407843   ENSP00000446723   ENSP00000446957   ENSP00000447964  

    Human Recombinant Protein Products for COQ10A: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for COQ10A 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane IEA--

    COQ10A for ontologies           About GeneDecksing



    COQ10A Antibody Products: 
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    Cloud-Clone Corp. CLIAs for COQ10A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR005031 Polyket_cyc
     IPR023393 START-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96MF6

    ProtoNet protein and cluster: Q96MF6

    1 Blocks protein domain: IPB005031 Streptomyces cyclase/dehydrase

    UniProtKB/Swiss-Prot: CQ10A_HUMAN, Q96MF6
    Similarity: Belongs to the COQ10 family


    COQ10A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CQ10A_HUMAN, Q96MF6
    Function: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be
    involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes
    (Probable)

    Animal Models:

       inGenious Targeting Laboratory - Custom generated mouse model solutions for COQ10A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COQ10A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COQ10A 
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate COQ10A:
    hsa-miR-3163 hsa-miR-548d-3p hsa-miR-548am hsa-miR-377 hsa-miR-548x hsa-miR-590-3p hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidCOQ10A 3' UTR sequence
    Inhib. RNA
    Products:
        
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                         Customized lentivirus expression plasmids for stable overexpression of COQ10A 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COQ10A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COQ10A

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for COQ10A (Q96MF62 ENSP000003125874) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC6ENSP000003340614STRING: ENSP00000334061
    COQ2ENSP000004092754STRING: ENSP00000409275
    --P310162MINT-8105251
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COQ10A (CQ10A)

    Search CenterWatch for drugs/clinical trials and news about COQ10A / CQ10A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COQ10A gene (2 alternative transcripts): 
    NM_001099337.1  NM_144576.3  

    Unigene Cluster for COQ10A:

    Coenzyme Q10 homolog A (S. cerevisiae)
    Hs.4096  [show with all ESTs]
    Unigene Representative Sequence: NM_144576
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000308197(uc001sko.4) ENST00000551566 ENST00000551911 ENST00000433805(uc001skp.4)
    ENST00000550071 ENST00000546614 ENST00000546544(uc001skq.4) ENST00000553234
    ENST00000549545 ENST00000551814
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COQ10A
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate COQ10A:
    hsa-miR-3163 hsa-miR-548d-3p hsa-miR-548am hsa-miR-377 hsa-miR-548x hsa-miR-590-3p hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidCOQ10A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for COQ10A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COQ10A
    Clone
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    OriGene clones in human, mouse for COQ10A (see all 11)
    OriGene ORF clones in mouse, rat for COQ10A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): COQ10A (NM_001099337)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COQ10A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COQ10A
    Sirion Biotech Customized lentivirus for stable overexpression of COQ10A 
                         Customized lentivirus expression plasmids for stable overexpression of COQ10A 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for COQ10A
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COQ10A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COQ10A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COQ10A

    Additional mRNA sequence: 

    AK057003.1 AK057014.1 AY358861.1 BC002435.2 BC026922.1 BC047444.1 BC073923.1 

    10 DOTS entries:

    DT.454513  DT.97838198  DT.87015080  DT.95371798  DT.100711716  DT.91908238  DT.99994396  DT.121203424 
    DT.100771658  DT.95371794 

    24/163 AceView cDNA sequences (see all 163):

    BQ723100 CA449301 AA459818 AI374593 BE275272 BQ954720 AA907400 CR591134 
    AA485873 CA390205 CR600865 CR594850 CR618951 CR623374 BM903862 AA809993 
    BC026922 BC002435 BF847942 BU690048 BQ268825 AY358861 AA921965 CR592454 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for COQ10A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b · 6c
    SP1:                    -     -     -           -     -     -     -           -                           
    SP2:                                -           -     -     -     -           -                           
    SP3:                                            -     -     -     -           -                           
    SP4:                    -     -     -           -     -     -                                             
    SP5:                                -           -     -     -     -                                       


    ECgene alternative splicing isoforms for COQ10A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COQ10A expression in normal human tissues (normalized intensities)      COQ10A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCCTGGCT
    COQ10A Expression
    About this image


    COQ10A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             vastus lateralis   
     
     Neuron (Nervous System)
             nerve   
     
     Adipose (Muscoskeletal System)
             Thoracic Perivascular Adipose

    See COQ10A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COQ10A

    SOURCE GeneReport for Unigene cluster: Hs.4096
        SABiosciences Custom PCR Arrays for COQ10A
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COQ10A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for COQ10A gene from 9/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Coq10a1 , 5 coenzyme Q10 homolog A (yeast)1, 5 89.07(n)1
    91.09(a)1
      10 (76.53 cM)5
    2105821  NM_001081040.11  NP_001074509.11 
     1283630975 
    chicken
    (Gallus gallus)
    Aves COQ10A1 coenzyme Q10 homolog A (S. cerevisiae) 75.38(n)
    84.31(a)
      770970  XM_001234287.2  XP_001234288.2 
    lizard
    (Anolis carolinensis)
    Reptilia COQ10A6
    --
    Uncharacterized protein
    67(a)
    38(a)
    1 ↔ 1
    possible ortholog
    2(93620758-93636797)
    6(72956736-72966418)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.36992 Transcribed sequence with moderate similarity to protein more 76.56(n)    141998386 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.125312 Transcribed sequence with moderate similarity to protein more 77.44(n)    AL915277.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94106
    --
    33(a)
    1 → many
    2R(2556529-2557581)
    worm
    (Caenorhabditis elegans)
    Secernentea R144.131 Protein R144.13 50.46(n)
    45.89(a)
      4363058  NM_001047401.1  NP_001040866.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G176501 Polyketide cyclase / dehydrase and lipid transport more 50.11(n)
    42.07(a)
      827485  NM_117873.3  NP_193500.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g07724001 hypothetical protein 49.52(n)
    39.52(a)
      4324708  NM_001050926.1  NP_001044391.1 


    ENSEMBL Gene Tree for COQ10A (if available)
    TreeFam Gene Tree for COQ10A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COQ10A gene
    COQ10B2  
    1 SIMAP similar gene for COQ10A using alignment to 3 protein entries:     CQ10A_HUMAN (see all proteins):
    COQ10B

    COQ10A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/137 SNPs in COQ10A are shown (see all 137)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs599173081,2
    C--56658708(+) CACCAC/TGCCCG 1 -- us2k10--------
    rs1868781081,2
    --56658776(+) TCGATC/TTCCTG 1 -- us2k10--------
    rs12745001,2
    C,F,A,H--56658859(-) ATAAAA/CGTCAG 1 -- us2k114Minor allele frequency- C:0.07NS EA NA 1816
    rs1912910971,2
    --56659290(+) GGGTTG/TCTGTC 2 -- us2k10--------
    rs766745291,2
    --56659299(+) TCCATA/GAGGTC 2 -- us2k10--------
    rs761511701,2
    C--56659320(+) TCAAGC/TGCACA 2 -- us2k14Minor allele frequency- T:0.06CSA WA NA EA 359
    rs1903038161,2
    --56659593(+) AAAGTA/GTTGTT 2 -- us2k10--------
    rs1448087671,2
    --56659655(+) GACTGG/TAAGGA 2 -- us2k10--------
    rs1821403781,2
    --56659662(+) AGGAAA/GTGACC 2 -- us2k10--------
    rs1852049821,2
    --56659733(+) GCTAGC/GCATGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for COQ10A (56660642 - 56664750 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for COQ10A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv482992CNV Complex15286789

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing COQ10A
    DNA2.0 Custom Variant and Variant Library Synthesis for COQ10A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for COQ10A:    About MalaCards
    familial hypercholesterolemia    hypercholesterolemia


    COQ10A for disorders           About GeneDecksing

    Genetic Association Database (GAD): COQ10A
    Human Genome Epidemiology (HuGE) Navigator: COQ10A (1 document)

    Export disorders for COQ10A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COQ10A gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with COQ10A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. The relationship between coenzyme Q10, oxidative stres s, and antioxidant enzymes activities and coronary artery disease. (PubMed id 22645453)1 Lee B.J....Lin P.T. (2012)
    6. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    7. Relationship between plasma coenzyme Q10, asymmetric d imethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy. (PubMed id 21640350)1 Young J.M....George P.M. (2011)
    8. Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipop rotein cholesterol in patients with coronary artery disease. (PubMed id 21458815)1 Toyama K....Ogawa H. (2011)
    9. Effects of acetylsalicylic acid on serum paraoxonase activity, Ox-LDL, coenzyme Q10 and other oxidative stress markers in healthy vo lunteers. (PubMed id 19891963)1 Kurban S. and Mehmetoglu I. (2010)
    10. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 93058 HGNC: 26515 AceView: FLJ32452 Ensembl:ENSG00000135469 euGenes: HUgn93058
    ECgene: COQ10A H-InvDB: COQ10A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COQ10A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COQ10A gene:
    Search GeneIP for patents involving COQ10A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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