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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COPS7B Gene

protein-coding   GIFtS: 47
GCID: GC02P232646

COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)

(Previous names: COP9 (constitutive photomorphogenic, Arabidopsis, homolog)...)
  Search for COPS7B
in our new
 Human Malady Compendium 
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for COPS7B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
COP9 Constitutive Photomorphogenic Homolog Subunit 7B (Arabidopsis)1 2     JAB1-Containing Signalosome Subunit 7b2 3
CSN7B1 2 3     COP9 (Constitutive Photomorphogenic, Arabidopsis, Homolog) Subunit 7B1
Signalosome Subunit 7b2 3     COP9 Signalosome Complex Subunit 7b2
SGN7b2 3     

External Ids:    HGNC: 167601   Entrez Gene: 647082   Ensembl: ENSG000001445247   UniProtKB: Q9H9Q23   

Export aliases for COPS7B gene to outside databases

Previous GC identifers: GC02P230710 GC02P231382 GC02P232610 GC02P232853 GC02P232476 GC02P232359 GC02P224495


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CSN7B_HUMAN, Q9H9Q2
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental
processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the
deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of
SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN,
I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent
phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively

Gene Wiki entry for COPS7B


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COPS7B gene promoter:
         HNF-4alpha2   HNF-4alpha1   NF-AT   NF-AT4   NF-AT2   POU2F1a   FOXJ2 (long isoform)   NF-AT3   FOXJ2   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOPS7B promoter sequence
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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPS7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.1   Ensembl cytogenetic band:  2q37.1   HGNC cytogenetic band: 2q37.1

COPS7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COPS7B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P232646:  view genomic region     (about GC identifiers)

Start:
232,646,381 bp from pter      End:
232,674,093 bp from pter
Size:
27,713 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CSN7B_HUMAN, Q9H9Q2 (See protein sequence)
Recommended Name: COP9 signalosome complex subunit 7b  
Size: 264 amino acids; 29622 Da
Subunit: Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COP6, COPS7 (COPS7A or
COPS7B) and COPS8. In the complex, it probably interacts directly with COPS1, COPS2, COPS4, COPS5, COPS6 and COPS8
Subcellular location: Cytoplasm. Nucleus
Secondary accessions: Q53S22 Q5BJG3 Q9H7V6
Alternative splicing: 3 isoforms:  Q9H9Q2-1   Q9H9Q2-2   Q9H9Q2-3   (Contains a phosphothreonine at position 261. Contains a phosphoserine at position 263)

Explore the universe of human proteins at neXtProt for COPS7B: NX_Q9H9Q2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H9Q2

  • COPS7B Protein expression data from MOPED and PaxDb:    About this image 
    COPS7B Protein Expression
    REFSEQ proteins: NP_073567.1  
    ENSEMBL proteins: 
     ENSP00000386567   ENSP00000386438   ENSP00000386527   ENSP00000401682   ENSP00000401235  
     ENSP00000272995   ENSP00000412548   ENSP00000401211   ENSP00000401110   ENSP00000409591  
     ENSP00000391207   ENSP00000386880   ENSP00000388499   ENSP00000362710   ENSP00000400739  
     ENSP00000403300  

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    Uscn Proteins for COPS7B

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0008180signalosome IDA18850735

    COPS7B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    COPS7B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000717 PCI_dom

    Graphical View of Domain Structure for InterPro Entry Q9H9Q2

    ProtoNet protein and cluster: Q9H9Q2

    1 Blocks protein family: IPB000717 Domain in components of the proteasome

    UniProtKB/Swiss-Prot: CSN7B_HUMAN, Q9H9Q2
    Similarity: Belongs to the CSN7/EIF3M family. CSN7 subfamily
    Similarity: Contains 1 PCI domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CSN7B_HUMAN, Q9H9Q2
    Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental
    processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the
    deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of
    SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN,
    I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent
    phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively

    Animal Models:

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPS7B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COPS7B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/25 Interacting proteins for COPS7B (Q9H9Q23 ENSP000002729954) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929053, ENSP000003505124I2D: score=3 STRING: ENSP00000350512
    COPS3Q9UNS23, ENSP000002687174I2D: score=1 STRING: ENSP00000268717
    COPS8Q996273, ENSP000003463404I2D: score=1 STRING: ENSP00000346340
    GPS1Q130983, ENSP000003472514I2D: score=1 STRING: ENSP00000347251
    COPS6Q7L5N13, ENSP000003041024I2D: score=2 STRING: ENSP00000304102
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010388cullin deneddylation IDA19141280

    COPS7B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COPS7B
    Search CenterWatch for drugs/clinical trials and news about COPS7B / CSN7B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COPS7B gene: 
    NM_022730.1  

    Unigene Cluster for COPS7B:

    COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
    Hs.335061  [show with all ESTs]
    Unigene Representative Sequence: AK126326
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000410024 ENST00000409295 ENST00000409091 ENST00000479430 ENST00000452375
    ENST00000449784 ENST00000466901 ENST00000350033(uc010fxy.1 uc002vsg.1)
    ENST00000412591 ENST00000413197(uc002vsi.1) ENST00000450501 ENST00000357490
    ENST00000432387 ENST00000492423 ENST00000410017 ENST00000412922 ENST00000373608(uc002vsh.1)
    ENST00000436564

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    hsa-miR-330-5p hsa-miR-15a hsa-miR-30d hsa-miR-449a hsa-miR-649 hsa-miR-424 hsa-miR-30a hsa-miR-3613-3p
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    Additional cDNA sequence: 

    AK022674.1 AK024273.1 AK098334.1 AK124133.1 AK126326.1 AK222879.1 AK307486.1 BC010739.1 
    BC091493.1 

    24/32 DOTS entries (see all 32):

    DT.100660759  DT.120961240  DT.95101842  DT.100660760  DT.95101843  DT.91766031  DT.209216  DT.95101840 
    DT.100660755  DT.120961230  DT.40126401  DT.120961278  DT.97805204  DT.120961294  DT.95347528  DT.91941986 
    DT.97825217  DT.100839717  DT.120961290  DT.120961300  DT.100026987  DT.100802312  DT.120961216  DT.120961228 

    24/163 AceView cDNA sequences (see all 163):

    CF139243 AU131883 AL599108 AL704051 AI685016 CB117191 CR591213 BE501977 
    CA390578 AW006694 CD358808 AK098334 CA421014 BU557005 BQ953525 CR607579 
    BX333333 BM471793 BF939657 AU125432 BU631172 BI906506 BU509858 BE501968 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for COPS7B (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                          -     -                 -     -     -           -     -                                   -                           
    SP2:                          -     -                 -     -     -           -     -                                   -     -                     
    SP3:                          -     -                 -     -     -           -     -                                                               
    SP4:                                -                 -     -     -           -                                         -     -                     
    SP5:                          -     -                 -     -     -     -     -     -                                   -     -                     


    ECgene alternative splicing isoforms for COPS7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COPS7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGCCCCCTG
    COPS7B Expression
    About this image
    See COPS7B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COPS7B

    SOURCE GeneReport for Unigene cluster: Hs.335061
        SABiosciences Custom PCR Arrays for COPS7B

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for COPS7B gene from 7/27 species (see all 27)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves COPS7B1 COP9 constitutive photomorphogenic homolog subunit more 81.19(n)
    92.05(a)
      424933  XM_422740.3  XP_422740.3 
    lizard
    (Anolis carolinensis)
    Reptilia COPS7B6
    --
    93(a)
    1 ↔ 1
    GL343304.1(1024317-1034321)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.172352 Xenopus laevis transcribed sequence with moderate similarity more 75.42(n)    BU908273.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa19h062 Danio rerio cDNA clone IMAGE4786730, partial cds 76.14(n)    BC059697.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CSN7b3
    CSN71
    COP9 complex homolog subunit 71 44(a)3
    52.79(n)1
    44.75(a)1
      44C63
    358161  NM_136535.21  NP_610379.21 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FUS51 COP9 signalosome complex subunit 7 46.61(n)
    37.56(a)
      839241  NM_202010.2  NP_973739.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g04908001 hypothetical protein 47.77(n)
    36.08(a)
      4343271  NM_001066213.1  NP_001059678.1 


    ENSEMBL Gene Tree for COPS7B (if available)
    TreeFam Gene Tree for COPS7B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COPS7B gene
    COPS7A2  
    5 SIMAP similar genes for COPS7B using alignment to 12 protein entries:     CSN7B_HUMAN (see all proteins):
    RANBP3    HDGFRP2    LOC284385    COPS7A    TBC1D22A

    COPS7B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/365 NCBI SNPs in COPS7B are shown (see all 365    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1431203511,2
    --232649167(+) AGCCGC/TGGTGA 1 -- us2k10--------
    rs1466620711,2
    --232649203(+) GAAAAA/CAAAAC 1 -- us2k10--------
    rs1165568081,2
    --232649235(+) CAGCCA/GTGGAG 1 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1391407311,2
    --232649283(+) GAATTG/TCTATG 1 -- us2k10--------
    rs1441370071,2
    --232649351(+) ATAGCC/GCTGTT 1 -- us2k10--------
    rs767645861,2
    F--232649373(+) AGCTCT/CAGACA 1 -- us2k11Minor allele frequency- C:0.03NA 120
    rs1451305611,2
    --232649613(+) CACCTA/CCTGGG 1 -- us2k10--------
    rs20148061,2
    F,A--232649653(+) GAGTAG/TCTGAG 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs20148071,2
    F,A--232649654(+) AGTAGC/TTGAGA 1 -- us2k11Minor allele frequency- T:0.02EA 120
    rs1845933651,2
    --232649757(+) CTCAGA/GTGATC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COPS7B (232646381 - 232674093 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for COPS7B
         2 CNVs: 35792 3408

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COPS7B gene, integrated from 9 sources (see all 39):
    (articles sorted by number of sources associating them with COPS7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. (PubMed id 18850735)1, 2 Fang L.... Huang L. (2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. (PubMed id 12628923)1, 2 Uhle S....Dubiel W. (2003)
    5. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. (PubMed id 12732143)1, 2 Groisman R.... Nakatani Y. (2003)
    6. Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome. (PubMed id 12220626)1, 2 Hoareau Alves K.... Jalinot P. (2002)
    7. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. (PubMed id 11337588)1, 2 Lyapina S.... Deshaies R.J. (2001)
    8. COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. (PubMed id 11285227)1, 2 Bech-Otschir D.... Dubiel W. (2001)
    9. The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. (PubMed id 9707402)1, 3 Wei N....Deng X.W. (1998)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64708 HGNC: 16760 AceView: COPS7B Ensembl:ENSG00000144524 euGenes: HUgn64708
    ECgene: COPS7B H-InvDB: COPS7B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COPS7B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COPS7B gene:
    Search GeneIP for patents involving COPS7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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