COPS4 Gene
protein-coding GIFtS: 49
GCID: GC04P083955
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|
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)(Previous names: COP9 (constitutive photomorphogenic, Arabidopsis, homolog)...)
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Aliases
for COPS4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| COP9 Constitutive Photomorphogenic Homolog Subunit 4 (Arabidopsis)1 2 | | JAB1-Containing Signalosome Subunit 42 3 | | CSN41 2 3 | | COP9 (Constitutive Photomorphogenic, Arabidopsis, Homolog) Subunit 41 | | Signalosome Subunit 42 3 | | COP9 Signalosome Complex Subunit 42 | | SGN42 3 | | MANOP15 |
Export aliases for COPS4 gene to outside databasesPrevious GC identifers: GC04P083880 GC04P084249 GC04P084348 GC04P084414 GC04P084313 GC04P079696 |
Summaries
for COPS4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for COPS4:
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functionsas an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar tothat of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding differentisoforms have been found for this gene. (provided by RefSeq, Apr 2012)
UniProtKB/Swiss-Prot: CSN4_HUMAN, Q9BT78Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmentalprocesses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating thedeneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity ofSCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN,IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependentphosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively
Gene Wiki entry for COPS4
|
Genomic Views
for COPS4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the COPS4 gene promoter:
E2F-3a E2F-4 RP58 E2F-5 MAZR E2F-2 Nkx2-5 Nkx5-1 E2F-1 E2F
Other transcription factors
Search SABiosciences Chromatin IP Primers for COPS4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPS4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q21.22 Ensembl cytogenetic band: 4q21.22 HGNC cytogenetic band: 4q21.22COPS4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P083955: view genomic region
(about GC identifiers)
Start:
|
83,955,600 bp from pter |
End:
|
83,996,971 bp from pter |
Size:
|
41,372 bases |
Orientation:
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plus strand |
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Proteins
for COPS4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CSN4_HUMAN, Q9BT78 (See
protein sequence)Recommended Name: COP9 signalosome complex subunit 4 Size: 406 amino acids; 46269 Da
Subunit: Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COP6, COPS7 (COPS7A orCOPS7B) and COPS8. In the complex, it probably interacts directly with COPS1, COPS2, COPS3, COPS5, COPS6, COPS7(COPS7A or COPS7B) and COPS8
Subcellular location: Cytoplasm. Nucleus
Secondary accessions: B3KN88 B3KST5 Q561W7 Q9NW31 Q9Y677Alternative splicing: 2 isoforms: Q9BT78-1 Q9BT78-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for COPS4: NX_Q9BT78
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BT78
COPS4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001244935.1 NP_057213.2
ENSEMBL proteins: ENSP00000425976 ENSP00000264389 ENSP00000425486 ENSP00000426788 ENSP00000424791 ENSP00000424655
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
COPS4 for ontologies About GeneDecksing
COPS4 Antibody Products:
Assay Products for COPS4: |
Protein
Domains /
Families
for COPS4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
COPS4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BT78ProtoNet protein and cluster: Q9BT78 UniProtKB/Swiss-Prot: CSN4_HUMAN, Q9BT78Similarity: Belongs to the CSN4 familySimilarity: Contains 1 PCI domain |
Function
for COPS4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CSN4_HUMAN, Q9BT78Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmentalprocesses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating thedeneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity ofSCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN,IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependentphosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPS4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPS4 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
COPS4 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for COPS4:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Cops4):
COPS4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for COPS4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COPS4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/130 Interacting proteins for COPS4 (Q9BT781, 2, 3 ENSP000002643894) via UniProtKB, MINT, STRING, and/or I2D (see all 130)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CCDC85B | Q158342, 3, ENSP000003116954 | MINT-66491 I2D:
score=5 STRING: ENSP00000311695 | | COPS3 | Q9UNS22, 3, ENSP000002687174 | MINT-7230300 I2D:
score=5 STRING: ENSP00000268717 | | MBIP | Q9NS732, 3, ENSP000003244444 | MINT-67774 I2D:
score=5 STRING: ENSP00000324444 | | RCBTB2 | O951992, 3, ENSP000003451444 | MINT-66264 I2D:
score=5 STRING: ENSP00000345144 | | COPS5 | Q929052, 3, ENSP000003505124 | MINT-7230300 I2D:
score=4 STRING: ENSP00000350512 |
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
COPS4 for ontologies About GeneDecksing
|
Drugs & Compounds
for COPS4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for COPS4
Search CenterWatch for drugs/clinical trials and news about COPS4 / CSN4
|
Transcripts
for COPS4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for COPS4 gene (2 alternative transcripts): NM_001258006.1 NM_016129.2 Unigene Cluster for COPS4: COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) Hs.190384 [show with all ESTs]Unigene Representative Sequence: AK09423811 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000509093 ENST00000264389(uc003hoa.3 uc010ijx.3) ENST00000511891
ENST00000509317 ENST00000510801 ENST00000506443 ENST00000507376 ENST00000503682
ENST00000511653 ENST00000511708 ENST00000504274
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPS4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPS4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: COPS4 (NM_016129) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COPS4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPS4 |
Additional cDNA sequence: AF100757.1 AK001148.1 AK001210.1 AK024005.1 AK094238.1 AK223178.1 BC004302.1 BC009292.2 BC093007.1 12 DOTS entries: DT.317318 DT.100655432 DT.91774237 DT.302737 DT.100638460 DT.100655433 DT.91774225 DT.91774236 DT.121226141 DT.91774222 DT.91774235 DT.95211323 24/322 AceView cDNA sequences (see all 322): AI248134 BQ944100 T32983 BC009292 AK001148 CR620449 AK024005 CB129315 CB146336 CR607122 AI131101 BQ066378 AA313920 BM823089 BM718990 CD513828 NM_016129 BM463124 CR620923 AI050906 AW024453 BQ063808 BM856359 AA453958
GeneLoc Exon Structure
|
Expression
for COPS4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| COPS4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTCTCCAAA
About this image
See COPS4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COPS4
SOURCE GeneReport for Unigene cluster: Hs.190384
SABiosciences Custom PCR Arrays for COPS4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPS4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COPS4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COPS4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COPS4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPS4 |
Orthologs
for COPS4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for COPS4 gene from 9/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cops41 , 5 |
COP9 (constitutive photomorphogenic) homolog, subunit more1, 5 |
90.64(n)1
99.51(a)1 |
|
5 (48.49 cM)5
268911 NM_012001.21 NP_036131.11
1005183095 |
chicken
(Gallus gallus) |
Aves |
COPS41 |
COP9 constitutive photomorphogenic homolog subunit more |
84.07(n)
99.01(a) |
|
422594 NM_001006447.1 NP_001006447.1 |
lizard
(Anolis carolinensis) |
Reptilia |
COPS46 |
-- |
94(a) |
1 ↔ 1 |
5(43173848-43181963) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.339352 |
Xenopus laevis transcribed sequence with strong similarity more |
79.64(n) |
|
CB199278.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc90c082 |
Danio rerio COP9, mRNA (cDNA clone IMAGE6791029) |
78.83(n) |
|
BC056527.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CSN41 , 3 |
photoreceptor differentiation (sensu
Drosophila)3
COP9 complex homolog subunit 41 |
72(a)3
64.38(n)1
72.52(a)1 |
|
357591 NM_001169609.11 NP_001163080.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
csn-46 |
COP9 signalosome complex subunit 4 |
35(a) |
1 ↔ 1 |
IV(1077490-1087015) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
COP81 |
COP9 signalosome complex subunit 4 |
55.14(n)
51.6(a) |
|
834312 NM_123663.2 NP_199111.1 |
rice
(Oryza sativa) |
Liliopsida |
Os03g01974001 |
hypothetical protein |
55.68(n)
52.75(a) |
|
4331948 NM_001055807.1 NP_001049272.1 |
ENSEMBL Gene Tree for COPS4 (if available)
TreeFam Gene Tree for COPS4 (if available) |
Paralogs
for COPS4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for COPS4 gene
- PSMD122
COPS4 for paralogs About GeneDecksing
|
Genomic Variants
for COPS4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COPS4 |
|
Disorders
/ Diseases
for COPS4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
COPS4 for disorders About GeneDecksing
OMIM gene information: 301590
OMIM disorders: --
3  diseases for COPS4: About MalaCardsmicrophthalmia syndromic 4 microphthalmia down syndrome
Export disorders for COPS4 gene to outside databases
|
Publications
for COPS4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for COPS4 gene, integrated from 9 sources (see all 59):
(articles sorted by number of sources associating them with COPS4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. (PubMed id 18850735)1, 2 Fang L.... Huang L. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. (PubMed id 12628923)1, 2 Uhle S....Dubiel W. (2003)
- The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. (PubMed id 12732143)1, 2 Groisman R.... Nakatani Y. (2003)
- Aberrant expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down syndrome brain (trisomy 21), AND MASS SPECTROMETRY. (PubMed id 11824616)1, 2 Peyrl A.... Lubec G. (2002)
- Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. (PubMed id 11337588)1, 2 Lyapina S.... Deshaies R.J. (2001)
- COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. (PubMed id 11285227)1, 2 Bech-Otschir D.... Dubiel W. (2001)
- The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. (PubMed id 9707402)1, 3 Wei N....Deng X.W. (1998)
- A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. (PubMed id 9535219)1, 2 Seeger M....Dubiel W. (1998)
|
External Searches for COPS4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing COPS4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing COPS4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing COPS4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for COPS4 gene:
Search GeneIP for patents involving COPS4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for COPS4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for COPS4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COPS4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPS4 | | | OriGene Protein Over-expression Lysate for COPS4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for COPS4 | | OriGene 3'-UTR Clone for COPS4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPS4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPS4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for COPS4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |
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| |
 |  |  |  | |
| | | | Search Tocris compounds for COPS4 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | COPS4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPS4 |
|  |  |  | | | | Search ThermoFisher Antibodies for COPS4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPS4 |
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