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COPRS Gene

protein-coding   GIFtS: 37
GCID: GC17M030180

Coordinator Of PRMT5, Differentiation Stimulator

(Previous name: chromosome 17 open reading frame 79)
(Previous symbol: C17orf79)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coordinator Of PRMT5, Differentiation Stimulator1 2     HSA2721962
C17orf791 2 3     TTP12
Cooperator Of PRMT51 2 3     Coordinator Of PRMT5 And Differentiation Stimulator2
COPR52 3     Protein TTP13
Chromosome 17 Open Reading Frame 791     

External Ids:    HGNC: 288481   Entrez Gene: 553522   Ensembl: ENSG000001723017   UniProtKB: Q9NQ923   

Export aliases for COPRS gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for COPRS Gene:
COPRS (coordinator of PRMT5, differentiation stimulator) is a protein-coding gene. GO annotations related to this gene include histone binding.

UniProtKB/Swiss-Prot: COPRS_HUMAN, Q9NQ92
Function: Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically
required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting
that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4
but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5.
Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment
of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for COPRS
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOPRS promoter sequence
   Search Chromatin IP Primers for COPRS

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COPRS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

COPRS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COPRS gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M030180:  view genomic region     (about GC identifiers)

Start:
30,178,883 bp from pter      End:
30,186,356 bp from pter
Size:
7,474 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: COPRS_HUMAN, Q9NQ92 (See protein sequence)
Recommended Name: Coordinator of PRMT5 and differentiation stimulator  
Size: 184 amino acids; 20066 Da
Subunit: Interacts with PRMT5. Interacts with histone H4; specifically interacts with the N-terminus of histone H4
but not with histone H3. Interacts with CBFB (By similarity). Found in a complex with PRMT5, RUNX1 and CBFB (By
similarity)
Secondary accessions: A6NP14 E1P656 Q96EF5 Q96P75

Explore the universe of human proteins at neXtProt for COPRS: NX_Q9NQ92

Explore proteomics data for COPRS at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See COPRS Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060875.2  
    ENSEMBL proteins: 
     ENSP00000304327   ENSP00000367901   ENSP00000464423   ENSP00000464429   ENSP00000464425  

    COPRS Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for COPRS 

     
    antibodies-online proteins for COPRS (4 products) 

     
    Search antibodies-online for peptides for COPRS

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    antibodies-online antibodies for COPRS 

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    antibodies-online kits for COPRS (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9NQ92


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COPRS_HUMAN, Q9NQ92
    Function: Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically
    required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting
    that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4
    but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5.
    Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment
    of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation
    (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18404153
    GO:0042393histone binding IDA18404153
         
    Find genes that share ontologies with COPRS           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for COPRS:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for COPRS

    miRNA
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    miRTarBase miRNAs that target COPRS:
    hsa-mir-193b-3p (MIRT016471), hsa-mir-421 (MIRT039412)

    Block miRNA regulation of human, mouse, rat COPRS using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate COPRS
    SwitchGear 3'UTR luciferase reporter plasmidCOPRS 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat COPRS

    Gene Editing
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COPRS
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPRS

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPRS


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COPRS_HUMAN, Q9NQ92: Nucleus

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    Find genes that share ontologies with COPRS           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COPRS
    Interactions:

        Search GeneGlobe Interaction Network for COPRS

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for COPRS (Q9NQ921, 2, 3 ENSP000003043274) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST4H4P628051, 2, 3, ENSP000003507674EBI-1642558,EBI-302023 MINT-6543302 MINT-6543349 MINT-6543323 I2D: score=2 STRING: ENSP00000350767
    HIST1H4AP628051, 2, 3EBI-1642558,EBI-302023 MINT-6543302 MINT-6543349 MINT-6543323 I2D: score=2 
    HIST1H4BP628051, 2, 3EBI-1642558,EBI-302023 MINT-6543302 MINT-6543349 MINT-6543323 I2D: score=2 
    HIST1H4CP628051, 2, 3EBI-1642558,EBI-302023 MINT-6543302 MINT-6543349 MINT-6543323 I2D: score=2 
    HIST1H4DP628051, 2, 3EBI-1642558,EBI-302023 MINT-6543302 MINT-6543349 MINT-6543323 I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007517muscle organ development ISS--
    GO:0043985histone H4-R3 methylation IDA18404153

    Find genes that share ontologies with COPRS           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COPRS



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for COPRS gene: 
    NM_018405.3  

    Unigene Cluster for COPRS:

    Coordinator of PRMT5, differentiation stimulator
    Hs.462729  [show with all ESTs]
    Unigene Representative Sequence: BQ946887
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302362(uc002hgp.3) ENST00000378634 ENST00000496655(uc010css.3)
    ENST00000579984 ENST00000579741
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidCOPRS 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat COPRS
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    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for COPRS
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      QuantiTect SYBR Green Assays in human, mouse, rat COPRS
      QuantiFast Probe-based Assays in human, mouse, rat COPRS

    Additional mRNA sequence: 

    AF407672.1 AJ272196.2 AK024772.1 BC012386.1 BC035483.1 

    5 DOTS entries:

    DT.315408  DT.97845780  DT.40203840  DT.91886787  DT.92437580 

    Selected AceView cDNA sequences (see all 272):

    AI127511 AI984914 BQ675109 CB070117 AA932026 AW593054 AA634427 AI202802 
    AA394162 N70503 BM313850 AI632114 BM664203 BG337023 AI245760 CB069631 
    BM852284 BE745844 BM703589 AI870378 AI632705 C21383 CA840953 CA841210 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for COPRS    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
    SP1:              -                                 
    SP2:                                                
    SP3:              -     -                           


    ECgene alternative splicing isoforms for COPRS

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    COPRS expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    COPRS Expression
    About this image

    COPRS Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COPRS Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.462729
        Custom PCR Arrays for COPRS
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPRS

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for COPRS gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Coprs1 , 5 RIKEN cDNA 2410022L05 gene5
    coordinator of PRMT5, differentiation stimulator1
    82.22(n)1
    78.18(a)1
      8 (6.41 cM)5
    664231  NM_025556.31  NP_079832.11 
     138847885 


    ENSEMBL Gene Tree for COPRS (if available)
    TreeFam Gene Tree for COPRS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for COPRS gene

    Find genes that share paralogs with COPRS           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for COPRS
    PGOHUM00000240365


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for COPRS (see all 182)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs799321231,2
    F--30178458(+) TGCTAG/CATCTA 1 -- int11Minor allele frequency- C:0.01NA 120
    rs1858216841,2
    --30178518(+) CCAAGC/TGTTTG 1 -- int10--------
    rs732780611,2
    C--30178519(+) CAAGCG/ATTTGA 1 -- int13Minor allele frequency- A:0.03WA NA 240
    rs1486695611,2
    --30178532(+) CTTTAA/CAATGT 1 -- int10--------
    rs1995132671,2
    --30178790(+) GTTCC-/AAACGA 1 -- int10--------
    rs80743831,2
    C,F,H--30178793(+) TCCAAT/CGAGCC 1 -- int119Minor allele frequency- C:0.08NS EA NA WA CSA 772
    rs1902976951,2
    --30179001(+) GACGGA/GGCCTT 1 -- ut310--------
    rs1413007651,2
    --30179033(+) ACACTC/GGTCTG 1 -- ut310--------
    rs1810698951,2
    C--30179137(+) CACCTA/GCAAGG 1 -- ut310--------
    rs2000904191,2
    --30179172(+) AGCATC/TGTCAA 2 N D mis10--------

    HapMap Linkage Disequilibrium report for COPRS (30178883 - 30186356 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for COPRS: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing COPRS
    DNA2.0 Custom Variant and Variant Library Synthesis for COPRS

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for COPRS gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with COPRS)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5. (PubMed id 18404153)1, 2, 3 Lacroix M....Fabbrizio E. (EMBO Rep. 2008)
    2. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. (PubMed id 10843809)1, 2, 3 Jenne D.E.... Thiel G. (Genomics 2000)
    3. Proteomic analysis of the NOS2 interactome in human airway epithelial cells. (PubMed id 23438482)1 Foster M.W....Marshall H.E. (Nitric Oxide 2013)
    4. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. (PubMed id 23184937)1 Xie Y....Cong F. (J. Biol. Chem. 2013)
    5. The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation. (PubMed id 22193545)1 Paul C....Fabbrizio E. (Cell Death Differ. 2012)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Defining the human deubiquitinating enzyme interaction landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (Cell 2009)
    8. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PubMed id 17620599)1 Xiao K....Lefkowitz R.J. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    9. Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. (PubMed id 17632510)1 Douglas J.... Rahman N. (Nat. Genet. 2007)
    10. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55352 HGNC: 28848 AceView: HSA272196 Ensembl:ENSG00000172301 euGenes: HUgn55352
    ECgene: COPRS H-InvDB: COPRS

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for COPRS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for COPRS gene:
    Search GeneIP for patents involving COPRS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for COPRS  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for COPRS  
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     OriGene qSTAR qPCR primer pairs in human, mouse for COPRS   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
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     OriGene Custom Antibody Services for COPRS   OriGene Custom Protein Services for COPRS  

     
     
     Block miRNA regulation of human, mouse, rat COPRS using miScript Target Protectors SeqTarget long-range PCR primers for resequencing COPRS
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COPRS Predesigned siRNA for gene silencing in human, mouse, rat COPRS
     QuantiFast Probe-based Assays in human, mouse, rat COPRS QuantiTect SYBR Green Assays in human, mouse, rat COPRS
     Custom PCR Arrays for COPRS Search Chromatin IP Primers for COPRS
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat COPRS Search GeneGlobe Interaction Network for COPRS
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     GenScript Custom Purified and Recombinant Proteins Services for COPRS GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for COPRS
     GenScript Custom Assay Services for COPRS GenScript Custom overexpressing Cell Line Services for COPRS
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for COPRS
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     COPRS antibodies
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     Search for Antibodies for COPRS at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for COPRS
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     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for COPRS
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPRS
     SwitchGear 3'UTR luciferase reporter plasmids for COPRS
     SwitchGear Promoter luciferase reporter plasmids for COPRS
     Search ThermoFisher Antibodies for COPRS
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPRS
     Browse compounds at ApexBio
     Search Addgene for plasmids for COPRS
      Search eBioscience for proteins for COPRS
      Search eBioscience for elisas for COPRS
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for COPRS
     antibodies-online antibodies for COPRS
     antibodies-online kits for COPRS (6 products)
      Search antibodies-online for peptides for COPRS
     antibodies-online proteins for COPRS (4 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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