COPG1 Gene
protein-coding GIFtS: 52
GCID: GC03P128969
|
|
coatomer protein complex, subunit gamma 1(Previous names: coatomer protein complex, subunit gamma )
(Previous symbol: COPG)
| |
Aliases
for COPG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coatomer Protein Complex, Subunit Gamma 11 2 | | Coatomer Subunit Gamma-12 | | COPG1 2 3 | | Gamma-1-COP3 | | Gamma-1-Coat Protein2 3 | | Gamma-COP1 | | Coatomer Protein Complex, Subunit Gamma1 | | Gamma-Coat Protein2 | | Coat Protein Gamma-Cop2 | | Gamma-1-COP3 | | Coatomer Subunit Gamma2 | | |
Export aliases for COPG1 gene to outside databases |
Summaries
for COPG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: COPG1_HUMAN, Q9Y678Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates withGolgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi upto the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for theretrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited bymembranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex alsoinfluences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDLreceptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating thepresence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association ofadipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity)
Gene Wiki entry for COPG1 (COPG)
|
Genomic Views
for COPG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for COPG1
Other transcription factors
Search SABiosciences Chromatin IP Primers for COPG1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPG1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q21.3 Ensembl cytogenetic band: 3q21.3 HGNC cytogenetic band: 3q21.3COPG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P128969: view genomic region
(about GC identifiers)
Start:
|
128,968,449 bp from pter |
End:
|
128,996,616 bp from pter |
Size:
|
28,168 bases |
Orientation:
|
plus strand |
|
Proteins
for COPG1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: COPG1_HUMAN, Q9Y678 (See
protein sequence)Recommended Name: Coatomer subunit gamma-1 Size: 874 amino acids; 97718 Da
Subunit: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.Interacts with ZNF289/ARFGAP2 through its C-terminal appendage domain. Interacts with EGFR upon EGF treatment;interaction is essential for regulation of EGF-dependent nuclear transport of EGFR by retrograde trafficking from theGolgi to the ER. Interacts with COPB1. Interacts with TMED10 (via C-terminus). Interacts with TMED2, TMED3, TMED7 andTMED9
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmicvesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Note=Thecoatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/budsoriginating from it (By similarity)
1 PDB 3D structure from  and Proteopedia  for COPG1:1R4X (3D)
Secondary accessions: A8K6M8 B3KMF6 Q54AC4Explore the universe of human proteins at neXtProt for COPG1: NX_Q9Y678
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y678
COPG1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057212.1
ENSEMBL proteins: ENSP00000325002 ENSP00000426457 ENSP00000422478 ENSP00000420916 Reactome Protein details: Q9Y678
Human Recombinant Protein Products for COPG1:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
COPG1 for ontologies About GeneDecksing
COPG1 Antibody Products:
Assay Products for COPG1: |
Protein
Domains /
Families
for COPG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
COPG1 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q9Y678ProtoNet protein and cluster: Q9Y678 1 Blocks protein family: IPB002553 Adaptin
UniProtKB/Swiss-Prot: COPG1_HUMAN, Q9Y678Similarity: Belongs to the COPG familySimilarity: Contains 4 HEAT repeats |
Function
for COPG1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: COPG1_HUMAN, Q9Y678Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates withGolgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi upto the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for theretrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited bymembranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex alsoinfluences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDLreceptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating thepresence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association ofadipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity) Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005198 | structural molecule activity |
IEA | -- |
COPG1 for ontologies About GeneDecksing
Phenotypes:
15 GenomeRNAi human phenotypes for COPG1:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Copg1):
COPG1 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for COPG1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COPG1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPG1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPG1 |
|
Pathways & Interactions
for COPG1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane | | | 2 | Clathrin-dependent protein traffic | | | 3 | COPII (Coat Protein 2) Mediated Vesicle Transport | | | 4 | Membrane Trafficking | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for COPG1
5  GeneGo (Thomson Reuters) Pathways for COPG1
5/7 
Reactome Pathways for COPG1 (see all 7)
COPG1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COPG1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/831 Interacting proteins for COPG1 (Q9Y6782, 3 ENSP000003250024) via UniProtKB, MINT, STRING, and/or I2D (see all 831)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| COPB1 | P536182, 3, ENSP000002499234 | MINT-7945693 MINT-8217717 MINT-7947479 I2D:
score=2 STRING: ENSP00000249923 | | ARCN1 | P484442, 3, ENSP000002640284 | MINT-7945693 MINT-8217717 MINT-7947479 I2D:
score=1 STRING: ENSP00000264028 | | COPB2 | P356062, 3, ENSP000003294194 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000329419 | | COPE | O145792, 3, ENSP000002628124 | MINT-8217717 I2D:
score=2 STRING: ENSP00000262812 | | H2AFX | P161042, 3, ENSP000003643104 | MINT-8257911 I2D:
score=2 STRING: ENSP00000364310 |
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006886 | intracellular protein transport |
IEA | -- | | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER |
TAS | -- | | GO:0016044 | cellular membrane organization |
TAS | -- | | GO:0048205 | COPI coating of Golgi vesicle |
TAS | -- | | GO:0051683 | establishment of Golgi localization |
ISS | -- |
COPG1 for ontologies About GeneDecksing
|
Drugs & Compounds
for COPG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for COPG1
Search CenterWatch for drugs/clinical trials and news about COPG1
|
Transcripts
for COPG1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for COPG1 gene: NM_016128.3 Unigene Cluster for COPG1: Coatomer protein complex, subunit gamma 1 Hs.518250 [show with all ESTs]Unigene Representative Sequence: AK30982110 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000314797(uc003els.3) ENST00000513965 ENST00000515725(uc010htb.3)
ENST00000504350 ENST00000509208 ENST00000504547 ENST00000513410 ENST00000509889
ENST00000514478 ENST00000512034
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for COPG1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COPG1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPG1 |
Additional cDNA sequence: AB047846.1 AF100756.1 AK001724.1 AK024721.1 AK025147.1 AK123939.1 AK291693.1 AK309821.1 BC020498.1 BC066650.1 24/27 DOTS entries (see all 27): DT.455897 DT.95214786 DT.100867033 DT.100661902 DT.95256084 DT.120857634 DT.120857671 DT.97854965 DT.100642880 DT.100661903 DT.120857834 DT.87015641 DT.92039405 DT.95256114 DT.100661901 DT.103151 DT.120857560 DT.120857637 DT.120857651 DT.120857769 DT.120857805 DT.86994889 DT.91668564 DT.91793454 24/450 AceView cDNA sequences (see all 450): BM750286 AI903934 N35983 BM739618 BQ228910 AW949278 BM674822 BF594592 CD108281 BE879764 BP353887 BE550081 BM755623 CF124971 BP365730 BM472575 T30400 BI333789 BM550267 BQ232313 AI754144 BU166173 BM750281 CB145105
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for COPG1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for COPG1
|
Expression
for COPG1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| COPG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTTATTGA
About this image
See COPG1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COPG1
SOURCE GeneReport for Unigene cluster: Hs.518250
SABiosciences Custom PCR Arrays for COPG1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPG1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat COPG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COPG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COPG1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPG1 |
Orthologs
for COPG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for COPG1 gene from 9/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Copg15
Copg1 |
coatomer protein complex, subunit gamma1, 5 |
89.17(n)1
97.25(a)1 |
|
6 (39.13 cM)5
541611 NM_017477.21 NP_059505.11
878878145 |
chicken
(Gallus gallus) |
Aves |
COPG1 |
coatomer protein complex, subunit gamma |
82.07(n)
93.36(a) |
|
416014 NM_001030597.1 NP_001025768.1 |
lizard
(Anolis carolinensis) |
Reptilia |
COPG6 |
-- |
82(a) |
1 ↔ 1 |
2(164652192-164679222) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC685332 |
hypothetical protein MGC68533 |
76.62(n) |
|
BC061661.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
copg22 |
coatomer protein complex, subunit gamma 2 |
77.18(n) |
|
30187 AF191561.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
gammaCop6 |
gamma-coatomer protein |
59(a) |
possible ortholog |
3R(27397865-27401429) |
worm
(Caenorhabditis elegans) |
Secernentea |
T14G10.56 |
Probable coatomer subunit gamma |
55(a) |
possible ortholog |
IV(10151927-10155615) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G344506 |
coatomer subunit gamma |
50(a) |
possible ortholog |
4(16471835-16477021) |
rice
(Oryza sativa) |
Liliopsida |
Os.79842 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
71.95(n) |
|
AK100095.1 |
ENSEMBL Gene Tree for COPG1 (if available)
TreeFam Gene Tree for COPG1 (if available) |
Paralogs
for COPG1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for COPG1 gene
- COPG22
3 SIMAP similar genes for COPG1 using alignment to 4 protein entries: COPG1_HUMAN (see all proteins):COPG COPG2 DKFZp761N09121
COPG1 for paralogs About GeneDecksing
|
Genomic Variants
for COPG1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for COPG1 (128968449 - 128996616 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for COPG1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COPG1 |
|
Disorders
/ Diseases
for COPG1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
COPG1 for disorders About GeneDecksing
3  diseases for COPG1: About MalaCardsanorexia nervosa cholesterol malaria
Export disorders for COPG1 gene to outside databases
|
Publications
for COPG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for COPG1 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with COPG1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of novel isoforms of COP I subunits. (PubMed id 11056392)1, 2, 3 Futatsumori M.... Nakayama K. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Gamma-COP appendage domain -- structure and function. (PubMed id 14690497)1, 2 Watson P.J.... Owen D.J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for COPG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing COPG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing COPG1 gene
(According to HUGE)
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Specialized Databases showing COPG1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for COPG1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for COPG1 gene:
Search GeneIP for patents involving COPG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for COPG1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for COPG1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COPG1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPG1 | | | OriGene Protein Over-expression Lysate for COPG1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for COPG1 | | OriGene 3'-UTR Clone for COPG1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPG1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for COPG1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for COPG1 | | OriGene Custom Protein Services for COPG1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COPG1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COPG1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPG1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COPG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COPG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COPG1 |
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| | | | Search Tocris compounds for COPG1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPG1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for COPG1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPG1 |
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