COPE Gene
protein-coding GIFtS: 59
GCID: GC19M019010
|
|
coatomer protein complex, subunit epsilon
| |
Aliases
for COPE gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coatomer Protein Complex, Subunit Epsilon1 2 | | Coatomer Subunit Epsilon2 | | Epsilon-COP3 | | Epsilon Coat Protein2 | | Epsilon-Coat Protein2 3 | | Epsilon-COP3 | | Coatomer Epsilon Subunit2 | | |
Export aliases for COPE gene to outside databasesPrevious GC identifers: GC19M019504 GC19M019402 GC19M018855 GC19M018871 GC19M018574 |
Summaries
for COPE gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for COPE:
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complexthat binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required forbudding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternativelyspliced transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: COPE_HUMAN, O14579Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates withGolgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi upto the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for theretrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited bymembranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex alsoinfluences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDLreceptors (By similarity)
Gene Wiki entry for COPE
|
Genomic Views
for COPE gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the COPE gene promoter:
AhR ER-alpha AML1a Bach2 MyoD Lmo2 CUTL1 Nkx2-5 HEN1 FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for COPE
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPE |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.11 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.11COPE Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M019010: view genomic region
(about GC identifiers)
Start:
|
19,010,323 bp from pter |
End:
|
19,030,199 bp from pter |
Size:
|
19,877 bases |
Orientation:
|
minus strand |
|
Proteins
for COPE gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: COPE_HUMAN, O14579 (See
protein sequence)Recommended Name: Coatomer subunit epsilon Size: 308 amino acids; 34482 Da
Subunit: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits
Subcellular location: Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmicside (By similarity). Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side(By similarity). Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as onthe vesicles/buds originating from it (By similarity)
Secondary accessions: A6NE29 A6NKA3 O76097 Q6IBB8 Q9UGP6Alternative splicing: 3 isoforms: O14579-1 O14579-2 O14579-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for COPE: NX_O14579
Post-translational modifications:
Phosphorylated by PKA1
Polyubiquitinated by RCHY1 in the presence of androgen, leading to proteasomal degradation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14579
COPE Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_009194.2 NP_955474.1 NP_955476.1
ENSEMBL proteins: ENSP00000262812 ENSP00000345674 ENSP00000343134 Reactome Protein details: O14579
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
COPE for ontologies About GeneDecksing
COPE Antibody Products:
Assay Products for COPE: |
Protein
Domains /
Families
for COPE gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
COPE for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O14579ProtoNet protein and cluster: O14579 1 Blocks protein family: IPB006822 Coatomer epsilon subunit
UniProtKB/Swiss-Prot: COPE_HUMAN, O14579Similarity: Belongs to the COPE family |
Function
for COPE gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: COPE_HUMAN, O14579Function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates withGolgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi upto the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for theretrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited bymembranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex alsoinfluences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDLreceptors (By similarity) Genatlas biochemistry entry for COPE:Golgi coatomer complex,epsilon subunit,component of the coat of non clathrin-coated vesicles,involved in the transportbetween endoplasmic reticulum and Golgi
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPE (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPE (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): COPE (NM_007263) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COPE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPE |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPE |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005198 | structural molecule activity |
IEA | -- |
COPE for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for COPE:
|
Pathways & Interactions
for COPE gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane | | | 2 | Clathrin-dependent protein traffic | | | 3 | COPII (Coat Protein 2) Mediated Vesicle Transport | | | 4 | Membrane Trafficking | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for COPE
5  GeneGo (Thomson Reuters) Pathways for COPE
5/7 
Reactome Pathways for COPE (see all 7)
COPE for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COPE
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/52 Interacting proteins for COPE (O145792, 3 ENSP000002628124) via UniProtKB, MINT, STRING, and/or I2D (see all 52)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER |
TAS | -- | | GO:0006891 | intra-Golgi vesicle-mediated transport |
ISS | -- | | GO:0015031 | protein transport |
IEA | -- | | GO:0016044 | cellular membrane organization |
TAS | -- | | GO:0048205 | COPI coating of Golgi vesicle |
TAS | -- |
COPE for ontologies About GeneDecksing
|
Drugs & Compounds
for COPE gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for COPE
1 HMDB Compound for COPE About this table
Search CenterWatch for drugs/clinical trials and news about COPE
|
Transcripts
for COPE gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for COPE gene (3 alternative transcripts): NM_007263.3 NM_199442.1 NM_199444.1 Unigene Cluster for COPE: Coatomer protein complex, subunit epsilon Hs.10326 [show with all ESTs]Unigene Representative Sequence: AK0233033 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262812(uc002nkk.3) ENST00000351079(uc002nkl.3) ENST00000349893(uc002nkm.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPE (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPE (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): COPE (NM_007263) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for COPE | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPE |
Additional cDNA sequence: AF092438.1 AJ131182.1 AJ249366.1 AK023303.1 AK222584.1 AK315281.1 AL136928.1 BC003155.1 BC007250.1 BC017285.2 CR456886.1 24/34 DOTS entries (see all 34): DT.102834041 DT.101985496 DT.97855884 DT.87003725 DT.100018835 DT.100038972 DT.100874709 DT.91813779 DT.95204732 DT.92066964 DT.102834040 DT.100841206 DT.100874690 DT.100874695 DT.97834998 DT.100874696 DT.121497850 DT.100874699 DT.121497955 DT.95204658 DT.100038974 DT.100874697 DT.100874700 DT.100874703 24/1024 AceView cDNA sequences (see all 1024): BM562603 CF126374 BM768349 BM769257 BM824906 NM_199444 BM769226 BM842638 BM850171 BQ279105 BQ007573 AI791350 BQ182571 CA420385 CF127478 BU539676 BG698529 CR590464 BM711903 BG679547 CA488192 BE561217 BM704739 BQ052374
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for COPE (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for COPE
|
Expression
for COPE gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| COPE expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGCCAGGAC
About this image
See COPE Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COPE
SOURCE GeneReport for Unigene cluster: Hs.10326
SABiosciences Custom PCR Arrays for COPE
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPE
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat COPE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COPE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COPE | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPE |
Orthologs
for COPE gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for COPE gene from 8/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cope1 , 5 |
coatomer protein complex, subunit epsilon1, 5 |
85.28(n)1
90.58(a)1 |
|
8 (34.15 cM)5
590421 NM_021538.11 NP_067513.11
703025185 |
chicken
(Gallus gallus) |
Aves |
COPE1 |
coatomer protein complex, subunit epsilon |
73.05(n)
78.9(a) |
|
420117 NM_001006339.1 NP_001006339.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
BU152767.12 |
-- |
81.26(n) |
|
BU152767.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.256292 |
Transcribed sequence with moderate similarity to protein more |
75.4(n) |
|
CK352667.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
BcDNA:LD298853
epsilonCOP1 |
retrograde (Golgi to ER) transport3
CG9543-PA1 |
39(a)3
53.88(n)1
40.14(a)1 |
|
26D93
339081 NM_135193.21 NP_609037.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
F45G2.41 , 3 |
Protein F45G2.41 |
37(a)3
48.41(n)1
37.46(a)1 |
|
III(13497638-13498864)3
1767661 NM_067370.31 NP_499771.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G348401 |
coatomer subunit epsilon-2 |
48.64(n)
43.06(a) |
|
818049 NM_129037.5 NP_181030.1 |
rice
(Oryza sativa) |
Liliopsida |
Os04g06126001 |
hypothetical protein |
52.59(n)
44.4(a) |
|
4336967 NM_001060382.1 NP_001053847.1 |
ENSEMBL Gene Tree for COPE (if available)
TreeFam Gene Tree for COPE (if available) |
Paralogs
for COPE gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for COPE gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for COPE (19010323 - 19030199 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for COPE
1 CNV: 10545 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COPE |
|
Disorders
/ Diseases
for COPE gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
COPE for disorders About GeneDecksing
OMIM gene information: 606942
OMIM disorders: --
7  diseases for COPE: About MalaCardsmumps cystic fibrosis hepatitis b fibrosis
hepatitis cholesterol malaria
Human Genome Epidemiology (HuGE) Navigator: COPE (22 documents)
Export disorders for COPE gene to outside databases
|
Publications
for COPE gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for COPE gene, integrated from 9 sources (see all 46):
(articles sorted by number of sources associating them with COPE) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes. (PubMed id 10469566)1, 2, 3 Shima D.T.... Pepperkok R. (1999)
- Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA. (PubMed id 17721809)1, 2 Maruyama S....Hatakeyama S. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking. (PubMed id 22337587)1 Haines D.S....Deshaies R.J. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for COPE gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing COPE gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing COPE gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing COPE gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for COPE | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for COPE gene:
Search GeneIP for patents involving COPE
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for COPE gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for COPE | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COPE | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COPE | | | OriGene Protein Over-expression Lysate for COPE | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for COPE | | OriGene 3'-UTR Clone for COPE | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COPE | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COPE | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for COPE | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for COPE | | OriGene Custom Protein Services for COPE | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COPE | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COPE | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COPE | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COPE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COPE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COPE |
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| | | | Search Tocris compounds for COPE |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COPE |
|  |  |  | | | | Search ThermoFisher Antibodies for COPE |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COPE |
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