Aliases for COMMD5 Gene
External Ids for COMMD5 Gene
GeneCards Summary for COMMD5 Gene
COMMD5 (COMM Domain Containing 5) is a Protein Coding gene.
UniProtKB/Swiss-Prot for COMMD5 Gene
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).