V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

COLQ Gene

protein-coding   GIFtS: 59

GC03M015466
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for COLQ

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EAD 1, 2, 5
FLJ55041 2
Descriptions
AChE Q subunit 2, 3
Acetylcholinesterase-associated collagen 2, 3
acetylcholinesterase collagen-like tail subunit 2
collagen-like tail subunit (single strand of homotrimer) of
asymmetric acetylcholinesterase 2
collagenic tail of endplate acetylcholinesterase 2
single strand of homotrimeric collagen-like tail subunit of
asymmetric acetylcholinesterase 2
External Ids
HGNC: 22261
Entrez Gene: 82922
UniProtKB: Q9Y2153
Ensembl: ENSG000002065617
Search outside databases for aliases for COLQ gene

Previous GC identifer: GC03M015420

Summaries
for COLQ

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for COLQ:
This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in
skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a
proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the
catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with
endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms
have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215
Function: Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina

Gene Wiki entry for COLQ

Genomic Location
for COLQ

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the COLQ gene  

Entrez Gene cytogenetic band: 3p25   Ensembl cytogenetic band:  3p24.3   HGNC cytogenetic band: 3p

COLQ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M015466:     (about GC identifiers)

Start:
 15,466,644 bp from pter
End:
 15,538,262 bp from pter
Size:
 71,619 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000003.10  NT_022517.17  

Proteins
for COLQ

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215 (See protein sequence)
Recommended Name: Acetylcholinesterase collagenic tail peptide precursor  
Size: 455 amino acids; 47766 Da
Subunit: Homotrimer. Component of the asymmetric form of AChE, a disulfide-bonded oligomer composed
of the collagenic subunits (Q) and a variable number of asymmetric catalytic subunits (T). The
N-terminal of a collagenic subunit (Q) associates with the C-terminal of a catalytic subunit (T)
Subcellular location: Cell junction, synapse
PDB structures from and Proteopedia :
1VZJ (3D)    
Secondary accessions: Q6DK18 Q6YH18 Q6YH19 Q6YH20 Q6YH21 Q9NP18 Q9NP19 Q9NP20 Q9NP21 Q9NP22 Q9NP23
Q9NP24 Q9UP88
Alternative splicing: 8 isoforms:  Q9Y215-1   Q9Y215-2   Q9Y215-3   Q9Y215-4   Q9Y215-5   Q9Y215-6   Q9Y215-7   Q9Y215-8   

Post-translational modifications:

  • The triple-helical tail is stabilized by disulfide bonds at each end1


    • REFSEQ proteins (5 alternative transcripts): 
    NP_005668.2  NP_536799.1  NP_536800.2  NP_536802.1  NP_536805.1  


    ENSEMBL proteins: 
    ENSP00000373293 ENSP00000373294 ENSP00000373292 ENSP00000373295 ENSP00000373291 ENSP00000373298 
    ENSP00000373297 ENSP00000373296 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (COLQ)
    Human Recombinant Proteins from Abnova (COLQ)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005605 basal lamina TAS9689136
    GO:0005615 extracellular space TAS9689136
    GO:0030054 cell junction IEA--
    GO:0045202 synapse IEA--
    About this table

    Antibodies for COLQ: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for COLQ
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (COLQ), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (COLQ)
    Novus Biologicals Antibody for COLQ

    Assays for COLQ: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for COLQ

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR011936 Myxo_disulph_rpt
     IPR008160 Collagen


       GeneDecks  COLQ for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9Y215

    ProtoNet protein and cluster: Q9Y215

    2 Blocks protein families:
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215
    Domain: The proline-rich attachment domain (PRAD) binds the AChE catalytic subunits
    Similarity: Belongs to the COLQ family
    Similarity: Contains 2 collagen-like domains

    Gene Function
    for COLQ

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (COLQ)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (COLQ)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 8): NM_080538

                  Applied Biosystems Silencer® siRNAs for COLQ

                  Sigma-Aldrich siRNA and siRNA Panels for COLQ  
                         Sigma-Aldrich shRNA Panels and shRNA for COLQ  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 5): NM_005677
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): NM_005677
                                     untagged cDNA clones in CMV expression vector (see all 8): NM_005677 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_005677

    UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215
    Function: Anchors the catalytic subunits of asymmetric AChE to the synaptic basal lamina

    Genatlas biochemistry entry for COLQ:
    collagen-like tail subunity,single strand of an homotrimer of the asymetric
    acetylcholinesterase,anchoring it into the basal lamina

    4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Colq):

    behavior/neurologicalgrowth/sizelife span-post-weaning/agingnervous system

    Pathways & Interactions
    for COLQ

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  COLQ 


    5/12 Interacting proteins for COLQ (ENSP000003732983) via UniProtKB, MINT, and/or STRING (see all 12 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACHEENSP000003500373STRING (score=.995)
    BCHEENSP000002643813STRING (score=.975)
    MUSKENSP000003635713STRING (score=.968)
    HSPG2ENSP000003638273STRING (score=.811)
    RAPSNENSP000002988543STRING (score=.742)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001507 acetylcholine catabolic process in synaptic cleft TAS9689136
    GO:0008105 asymmetric protein localization TAS9689136
    GO:0042135 neurotransmitter catabolic process IEA--
    About this table

    Drugs & Compounds
    for COLQ

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for COLQ
    1 Novoseek chemical compound relationship for COLQ gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    proline 37.57 3 18076380 (1), 16114264 (1)
    About this table


    Transcripts
    for COLQ

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (COLQ)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (COLQ)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 8): NM_080538

                  Sigma-Aldrich siRNA and siRNA Panels for COLQ  
                         Sigma-Aldrich shRNA Panels and shRNA for COLQ  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_005677  NM_080538  NM_080539  NM_080541  NM_080544  

    REFSEQ mRNAs for COLQ gene (5 alternative transcripts): 

    NM_005677.3   NM_080538.2   NM_080539.3   NM_080541.2   NM_080544.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_005677  NM_080538  NM_080539  NM_080541  NM_080544  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 5): NM_005677
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): NM_005677
                                     untagged cDNA clones in CMV expression vector (see all 8): NM_005677 

    Additional cDNA sequence: 

    AF057036.1 AJ225895.1 AK128401.1 AK289688.1 AY150334.1 AY150335.1 AY150336.1 AY150337.1 
    AY150338.1 AY150339.1 BC074828.2 BC074829.2 BC126363.1 BC144004.1 

    7 DOTS entries:

    DT.40275712  DT.100020969  DT.101977323  DT.100020967  DT.100020968  DT.100020971  DT.91997782 

    24/38 AceView cDNA sequences (see all 38 ):

    NM_005677 BC074828 AK128401 AI690739 AY150334 BC074829 BQ012516 AY150338 
    NM_080540 AJ225895 NM_080543 AY150336 AF057036 AI140900 AY150337 BX500613 
    BQ012249 AI247649 AY150335 BG236245 NM_080542 AI554171 AY150339 NM_080539 

    highest scoring ESTs for COLQ:

    AF057036 AJ225895 AY150334 AY150335 AY150336 AY150337 AY150338 AY150339 AA010938 AI140900 

    Unigene Cluster for COLQ:

    Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
    Hs.146735  [show with all ESTs]
    Unigene Representative Sequence: NM_080538


    GeneLoc Exon Structure

    8 Ensembl transcripts including schematic representations:
    ENST00000383783  ENST00000383784  ENST00000383782  ENST00000383785  ENST00000383781  ENST00000383788  
    ENST00000383787  ENST00000383786  

    Expression
    for COLQ

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    COLQ expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for COLQ

    1 / 2 / 3

    3 probe-sets matching COLQ gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    37858_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AF057036 1.00 0.90 0.95 1

    		206073_at2, 3 U133-A 1 1.00 1.00 -- -- AF057036 1.00 0.90 0.95 1

    		206073_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  COLQ for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: CTGCTTCCAC

    SOURCE GeneReport for Unigene cluster: Hs.146735

    Expression variation in blood from EXPOLDB for COLQ

    UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215
    Tissue specificity: Found at the end plate of skeletal muscle

    Orthologs
    for COLQ

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for COLQ gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 COLQ1   -- collagen-like tail subunit (single strand of homotrimer) more 91.95(n)
    89.71(a)    		 608697  XM_858278.1  XP_863371.1 
    chimpanzee
    (Pan troglodytes)    		 COLQ1   -- collagen-like tail subunit (single strand of homotrimer) more 96.6(n)
    96.44(a)    		 743693  XM_001159719.1  XP_001159719.1 
    cow
    (Bos taurus)    		 COLQ1   -- collagen-like tail subunit (single strand of homotrimer) more 75.87(n)
    75.24(a)    		 514615  NM_001035297.1  NP_001030374.1 
    rat
    (Rattus norvegicus)    		 Colq1   -- collagen-like tail subunit (single strand of homotrimer) more 88.33(n)
    89.52(a)    		 29755  NM_019274.1  NP_062147.1 
    mouse
    (Mus musculus)    		 Colq1, 5 145
    		 collagen-like tail subunit (single strand of homotrimer) more1, 5 90.02(n)1
    90.76(a)1    		 3828641  NM_009937.11  NP_034067.11 
     AF0154755  AF0154765  (see all 15)
    About this table        Species with no ortholog for COLQ

    ENSEMBL Gene Tree for COLQ

    Paralogs
    for COLQ

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    		  --

    SNPs/Variants
    for COLQ

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/415 NCBI SNPs in COLQ are shown (see all 415 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 168)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 3 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs32741,2
    		A,C,F,H,O15466760(-) GCAGCC/TCTGTT 5 -- ut31 ese39Minor allele frequency- T:0.38NA MN EU EA WA 916
    rs38461271,2
    		A,C,F,H15466531(+) ACATTC/GTAGAA 5 -- ng517Minor allele frequency- G:0.49EU EA WA NA 558
    rs67778121,2
    		A,C,F,H15517294(+) TAAGTC/TAAATT 5 -- int1 ng314Minor allele frequency- T:0.29EU EA WA 420
    rs9896821,2
    		A,C,F,H15539457(+) caaaaA/Gtcctc 4 -- ng318Minor allele frequency- G:0.49EU EA WA 808
    rs26053961,2
    		C,F,H,O15515477(-) TCAAGG/TCGGTT 5 -- int1 ng3111Minor allele frequency- T:0.46EU EA WA NA 978
    rs22789611,2
    		A,C,F,H15467811(-) ACACAT/CAGACC 5 -- ut31 ese310Minor allele frequency- C:0.49EA NA EU WA 2226
    rs98217931,2
    		A,C,F,H15516041(+) tgagaG/Ttggtc 5 -- int1 ng318Minor allele frequency- T:0.45EU EA WA 838
    rs22789621,2
    		A,C,F,H15467790(-) TTTAGA/TATGTT 5 -- ut3112Minor allele frequency- T:0.48EA NA EU WA 2480
    --
    rs38066601,2
    		A,C,F15538361(-) ATGGGG/AGACAG 4 -- ng311Minor allele frequency- A:0.36EA 1472
    rs67829801,2
    		C,F,H15474717(+) GGAACT/CGGGCC 5 G/S mis1 int1 ese38Minor allele frequency- C:0.06EU EA WA 840
    About this table

    HapMap Linkage Disequilibrium images for COLQ (up to first 250kb)

    Disorders & Mutations
    for COLQ

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 603033   disorders: 603034  

    UniProtKB/Swiss-Prot: COLQ_HUMAN, Q9Y215

  • Defects in COLQ are the cause of congenital myasthenic syndrome Engel type (CMSE)
    [MIM:603034]; also known as end-plate acetylcholinesterase deficiency or congenital myasthenic
    syndrome type IC (CMS-IC). CMSE is a rare autosomal recessive congenital myastehnic syndrome
    characterized by onset during childhood, generalized weakness, abnormal fatigability on exertion,
    refrectoriness to acetylcholinesterase drugs, decremental electromyographic response and
    morphological abnormalities of the neuromuscular junctions

    • 5 Novoseek disease relationships for COLQ gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    endplate acetylcholinesterase deficiency 97.10 3 12609505 (1), 9689136 (1), 17300939 (1)
    myasthenic syndromes congenital 92.94 5 15248101 (2), 11865139 (1), 17300939 (1), 9758617 (1)
    nasopharyngeal carcinoma 65.21 2 8820030 (1), 1651778 (1)
    connective tissue diseases 43.69 1 2173736 (1)
    tumors 0.00 1 1309425 (1)
    About this table

    GeneTests: COLQ
    Congenital Myasthenic Syndromes

    Human Gene Mutation Database: COLQ
    Genetic Association Database: COLQ

    Medical News
    for COLQ

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for COLQ

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/54 PubMed articles for COLQ gene (see all 54 ):

    Search for COLQ

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing COLQ

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 8292 HGNC: 2226 AceView: COLQ Ensembl:ENSG00000206561 euGenes: HUgn8292
    ECgene: COLQ H-InvDB: COLQ

    Other Databases showing COLQ

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing COLQ

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    GeneReviewshttp://www.genetests.org/query?gene=COLQ

    Licensable Technologies
    for COLQ

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for COLQ

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for COLQ:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for COLQ-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for COLQ Antibodies for COLQ
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for COLQ Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (COLQ)
     Antibodies (COLQ)
     Chimera RNAi (COLQ)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (COLQ)
     Antibodies (COLQ)
     Search OriGene for COLQ
     Search Tocris compounds for COLQ




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for COLQ

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    COLQ Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com