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Aliases for COLEC10 Gene

Aliases for COLEC10 Gene

  • Collectin Sub-Family Member 10 (C-Type Lectin) 2 3
  • CLL1 3 4 6
  • Collectin Liver Protein 1 3 4
  • Collectin-34 3 4
  • CL-34 3 4
  • Collectin Liver 1 3
  • Collectin 34 3
  • Collectin-10 3
  • CL-L1 4

External Ids for COLEC10 Gene

Previous GeneCards Identifiers for COLEC10 Gene

  • GC08P119066
  • GC08U900019
  • GC08P119676
  • GC08P120036
  • GC08P120148
  • GC08P115407
  • GC08P120007

Summaries for COLEC10 Gene

Entrez Gene Summary for COLEC10 Gene

  • This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq, Jul 2008]

GeneCards Summary for COLEC10 Gene

COLEC10 (Collectin Sub-Family Member 10 (C-Type Lectin)) is a Protein Coding gene. GO annotations related to this gene include mannose binding. An important paralog of this gene is COLEC11.

UniProtKB/Swiss-Prot for COLEC10 Gene

  • Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COLEC10 Gene

Genomics for COLEC10 Gene

Regulatory Elements for COLEC10 Gene

Genomic Location for COLEC10 Gene

118,952,288 bp from pter
119,106,968 bp from pter
154,681 bases
Plus strand

Genomic View for COLEC10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for COLEC10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for COLEC10 Gene

Proteins for COLEC10 Gene

  • Protein details for COLEC10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • Q3SYH6
    • Q6UW19

    Protein attributes for COLEC10 Gene

    277 amino acids
    Molecular mass:
    30705 Da
    Quaternary structure:
    No Data Available

neXtProt entry for COLEC10 Gene

Proteomics data for COLEC10 Gene at MOPED

Post-translational modifications for COLEC10 Gene

  • Glycosylation at Asn258
  • Modification sites at PhosphoSitePlus

Other Protein References for COLEC10 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for COLEC10 Gene

Domains for COLEC10 Gene

Gene Families for COLEC10 Gene


Suggested Antigen Peptide Sequences for COLEC10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9Y6Z7
  • Contains 1 C-type lectin domain.
  • Contains 1 collagen-like domain.
  • Belongs to the COLEC10/COLEC11 family.
genes like me logo Genes that share domains with COLEC10: view

Function for COLEC10 Gene

Molecular function for COLEC10 Gene

UniProtKB/Swiss-Prot Function:
Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine.

Gene Ontology (GO) - Molecular Function for COLEC10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005537 mannose binding IEA --
genes like me logo Genes that share ontologies with COLEC10: view

Animal Model Products

CRISPR Products

miRNA for COLEC10 Gene

miRTarBase miRNAs that target COLEC10

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for COLEC10

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for COLEC10 Gene

Localization for COLEC10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for COLEC10 Gene

Secreted. Note=According to PubMed:10224141, cytoplasmic.

Subcellular locations from

Jensen Localization Image for COLEC10 Gene COMPARTMENTS Subcellular localization image for COLEC10 gene
Compartment Confidence
extracellular 5
cytoskeleton 1
cytosol 1
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for COLEC10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005581 collagen trimer IEA --
GO:0005737 cytoplasm IDA 10224141
genes like me logo Genes that share ontologies with COLEC10: view

Pathways for COLEC10 Gene

SuperPathways for COLEC10 Gene

No Data Available

Interacting Proteins for COLEC10 Gene

Gene Ontology (GO) - Biological Process for COLEC10 Gene


No data available for Pathways by source for COLEC10 Gene

Transcripts for COLEC10 Gene

mRNA/cDNA for COLEC10 Gene

(3) REFSEQ mRNAs :
(14) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for COLEC10 Gene

Collectin sub-family member 10 (C-type lectin):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for COLEC10

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for COLEC10 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: -

Relevant External Links for COLEC10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for COLEC10 Gene

mRNA expression in normal human tissues for COLEC10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for COLEC10 Gene

This gene is overexpressed in Liver (42.3).

Protein differential expression in normal tissues for COLEC10 Gene

This gene is overexpressed in Serum (53.2) and Plasma (14.5).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for COLEC10 Gene

SOURCE GeneReport for Unigene cluster for COLEC10 Gene Hs.176615

mRNA Expression by UniProt/SwissProt for COLEC10 Gene

Tissue specificity: Highly expressed in liver, placenta and adrenal gland. Moderately expressed in small intestine, lung, stomach and prostate. Weakly expressed in trachea and spleen.
genes like me logo Genes that share expressions with COLEC10: view

Expression partners for COLEC10 Gene

In Situ Assay Products

Orthologs for COLEC10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for COLEC10 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia COLEC10 35
  • 90.13 (n)
  • 93.5 (a)
COLEC10 36
  • 93 (a)
(Canis familiaris)
Mammalia COLEC10 35
  • 91.46 (n)
  • 94.22 (a)
COLEC10 36
  • 94 (a)
(Mus musculus)
Mammalia Colec10 35
  • 86.04 (n)
  • 88.81 (a)
Colec10 16
Colec10 36
  • 89 (a)
(Pan troglodytes)
Mammalia COLEC10 35
  • 99.64 (n)
  • 99.64 (a)
COLEC10 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Colec10 35
  • 86.59 (n)
  • 88.77 (a)
(Monodelphis domestica)
Mammalia COLEC10 36
  • 75 (a)
(Gallus gallus)
Aves COLEC10 35
  • 73.01 (n)
  • 69.78 (a)
COLEC10 36
  • 68 (a)
(Anolis carolinensis)
Reptilia COLEC10 36
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia colec10 35
  • 68.82 (n)
  • 64.64 (a)
(Danio rerio)
Actinopterygii COLEC10 36
  • 42 (a)
Species with no ortholog for COLEC10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for COLEC10 Gene

Gene Tree for COLEC10 (if available)
Gene Tree for COLEC10 (if available)

Paralogs for COLEC10 Gene

Paralogs for COLEC10 Gene

Selected SIMAP similar genes for COLEC10 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with COLEC10: view

Variants for COLEC10 Gene

Sequence variations from dbSNP and Humsavar for COLEC10 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs923100 -- 119,003,068(+) ATGCA(C/T)GTGTA intron-variant
rs975883 -- 119,077,526(-) TTAAG(A/C)CCAGA intron-variant
rs975884 -- 119,077,316(-) AGGCC(A/C)CATTA intron-variant
rs996789 -- 119,074,166(-) CTCTA(G/T)GTCCC intron-variant
rs1064556 -- 119,106,378(+) GGTAT(A/G)TTATT utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for COLEC10 Gene

Variant ID Type Subtype PubMed ID
essv8481 CNV CNV 17122850
essv5532 CNV CNV 17122850
esv2674983 CNV Deletion 23128226
esv2668821 CNV Deletion 23128226
esv22200 CNV Loss 19812545

Relevant External Links for COLEC10 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COLEC10 Gene

Disorders for COLEC10 Gene

Relevant External Links for COLEC10

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for COLEC10 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for COLEC10 Gene

Publications for COLEC10 Gene

  1. Molecular cloning of a novel human collectin from liver (CL-L1). (PMID: 10224141) Ohtani K. … Wakamiya N. (J. Biol. Chem. 1999) 2 3 4 23
  2. Molecular cloning of mouse collectin liver 1. (PMID: 12450124) Kawai T. … Wakamiya N. (Biosci. Biotechnol. Biochem. 2002) 3 23
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  4. Multiple genetic loci for bone mineral density and fractures. (PMID: 18445777) Styrkarsdottir U. … Stefansson K. (N. Engl. J. Med. 2008) 3
  5. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. (PMID: 19801982) Rivadeneira F. … Uitterlinden A.G. (Nat. Genet. 2009) 3

Products for COLEC10 Gene

Sources for COLEC10 Gene

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