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Aliases for COLCA2 Gene

Aliases for COLCA2 Gene

  • Colorectal Cancer Associated 2 2 3
  • Cancer Susceptibility Candidate Protein 13 3 4
  • Cancer Susceptibility Candidate 13 2 3
  • C11orf93 3 4
  • CASC13 3 4
  • Colorectal Cancer-Associated Protein 2 3
  • Chromosome 11 Open Reading Frame 93 2
  • Colorectal Cancer Associated Two 3

External Ids for COLCA2 Gene

Previous Symbols for COLCA2 Gene

  • C11orf93

Summaries for COLCA2 Gene

GeneCards Summary for COLCA2 Gene

COLCA2 (Colorectal Cancer Associated 2) is a Protein Coding gene. Diseases associated with COLCA2 include colorectal cancer.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COLCA2 Gene

Genomics for COLCA2 Gene

Genomic Location for COLCA2 Gene

111,298,356 bp from pter
111,308,735 bp from pter
10,380 bases
Plus strand

Genomic View for COLCA2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for COLCA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for COLCA2 Gene

No data available for Regulatory Elements for COLCA2 Gene

Proteins for COLCA2 Gene

  • Protein details for COLCA2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Colorectal cancer-associated protein 2
    Protein Accession:
    Secondary Accessions:
    • E9PMJ8
    • Q2TBJ3
    • V5LD62
    • V5LDI3
    • V5LDV1
    • V5LE09
    • V5LEU3

    Protein attributes for COLCA2 Gene

    154 amino acids
    Molecular mass:
    16850 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI10080.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AP002448; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for COLCA2 Gene


neXtProt entry for COLCA2 Gene

Proteomics data for COLCA2 Gene at MOPED

Post-translational modifications for COLCA2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for COLCA2 Gene

Domains for COLCA2 Gene

Protein Domains for COLCA2 Gene

genes like me logo Genes that share domains with COLCA2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for COLCA2 Gene

Function for COLCA2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for COLCA2 Gene

Localization for COLCA2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for COLCA2 Gene


Gene Ontology (GO) - Cellular Components for COLCA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 24154973
genes like me logo Genes that share ontologies with COLCA2: view

Pathways for COLCA2 Gene

SuperPathways for COLCA2 Gene

No Data Available

Interacting Proteins for COLCA2 Gene

Gene Ontology (GO) - Biological Process for COLCA2 Gene


No data available for Pathways by source for COLCA2 Gene

Transcripts for COLCA2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for COLCA2 Gene

No ASD Table

Relevant External Links for COLCA2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for COLCA2 Gene

mRNA expression in normal human tissues for COLCA2 Gene

mRNA Expression by UniProt/SwissProt for COLCA2 Gene

Tissue specificity: Expressed in many cell types of epithelial, mesenchymal and hematopoietic origins.
genes like me logo Genes that share expressions with COLCA2: view

Orthologs for COLCA2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for COLCA2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia COLCA2 36
  • 99.47 (n)
  • 99.2 (a)
  • 99 (a)
(Bos Taurus)
Mammalia LOC100294918 36
  • 83 (n)
  • 76.11 (a)
(Canis familiaris)
Mammalia COLCA2 36
  • 84.46 (n)
  • 77.69 (a)
  • 53 (a)
(Mus musculus)
Mammalia Gm684 36
  • 78.34 (n)
  • 67.93 (a)
Gm684 37
  • 41 (a)
(Ornithorhynchus anatinus)
Mammalia COLCA2 37
  • 27 (a)
(Rattus norvegicus)
Mammalia RGD1563866 36
  • 77.73 (n)
  • 68.42 (a)
(Gallus gallus)
Aves COLCA2 37
  • 38 (a)
LOC101751781 36
  • 57.81 (n)
  • 46.41 (a)
(Anolis carolinensis)
Reptilia COLCA2 37
  • 21 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734888 36
  • 52.95 (n)
  • 39.82 (a)
Species with no ortholog for COLCA2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for COLCA2 Gene

Gene Tree for COLCA2 (if available)
Gene Tree for COLCA2 (if available)

Paralogs for COLCA2 Gene

No data available for Paralogs for COLCA2 Gene

Variants for COLCA2 Gene

Sequence variations from dbSNP and Humsavar for COLCA2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2390 -- 111,304,560(-) ATCAT(A/T)AAACA intron-variant
rs1046872 -- 111,308,665(+) TTTCA(A/G)TTGTT utr-variant-3-prime
rs1054791 -- 111,303,810(+) CAAAA(A/G)AGGTG intron-variant
rs2002562 -- 111,308,466(+) ATGGC(A/G)TGGGT utr-variant-3-prime
rs3087587 -- 111,308,329(-) TCTGC(C/T)GCCTG reference, synonymous-codon

Relevant External Links for COLCA2 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Structural Variations from Database of Genomic Variants (DGV) for COLCA2 Gene

Disorders for COLCA2 Gene

(1) MalaCards Diseases for COLCA2 Gene

Search for COLCA2 Gene in MalaCards »
genes like me logo Genes that share disorders with COLCA2: view

No data available for UniProtKB/Swiss-Prot for COLCA2 Gene

Publications for COLCA2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. (PMID: 21071539) He J. … Haiman C.A. (Cancer Epidemiol. Biomarkers Prev. 2011) 2 3
  4. Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. (PMID: 24154973) Peltekova V.D. … Hudson T.J. (Int. J. Cancer 2013) 3 4
  5. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. (PMID: 24836286) Zhang B. … Zheng W. (Nat. Genet. 2014) 3

Products for COLCA2 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate COLCA2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for COLCA2
    • Block miRNA regulation of COLCA2 using miScript Target Protectors

    Sources for COLCA2 Gene

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