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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

COL28A1 Gene

protein-coding GIFtS: 48
GCID: GC07M007364

collagen, type XXVIII, alpha 1

Search for COL28A1
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Collagen, Type XXVIII, Alpha 1¹ ²
COL28² ³
Collagen Alpha-1(XXVIII) Chain²

External Ids:	HGNC: 22442¹	Entrez Gene: 340267²	Ensembl: ENSG00000215018⁷	OMIM: 609996⁵	UniProtKB: Q2UY09³

Export aliases for COL28A1 gene to outside databases

Previous GC identifer: GC07M007246

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COL28A1:

COL28A1 belongs to a class of collagens containing von Willebrand factor (VWF; MIM 613160) type A (VWFA) domains (Veit

et al., 2006 (PubMed 16330543)).(supplied by OMIM, Nov 2010)

UniProtKB/Swiss-Prot: COSA1_HUMAN, Q2UY09

Function: May act as a cell-binding protein

Gene Wiki entry for COL28A1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the COL28A1 gene promoter:
POU2F1 HNF-1 POU2F1b POU2F1a POU2F1c CUTL1 HNF-1A
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): COL28A1 promoter sequence

Search SABiosciences Chromatin IP Primers for COL28A1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COL28A1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.3 Ensembl cytogenetic band: 7p21.3 HGNC cytogenetic band: 7p21.3

COL28A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL28A1 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M007364: view genomic region (about GC identifiers)

Start:	7,395,834 bp from pter	End:	7,575,484 bp from pter
Size:	179,651 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 7,445,378-7,622,650

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: COSA1_HUMAN, Q2UY09 (See protein sequence)

Recommended Name: Collagen alpha-1(XXVIII) chain precursor

Size: 1125 amino acids; 116657 Da

Subunit: Trimer or homomer. Secreted into as a 135 kDa monomer under reducing conditions and as a homotrimer under

non-reducing conditions (By similarity)

Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane (By similarity)

Sequence caution: Sequence=EAL24305.1; Type=Erroneous gene model prediction; Sequence=EAL24306.1; Type=Erroneous gene

model prediction; Sequence=EAL24307.1; Type=Erroneous gene model prediction;

Secondary accessions: A4D101 A4D106 A4D107 A8MVR2 B9EGX9 Q2UY07 Q2UY08

Alternative splicing: 3 isoforms: Q2UY09-1 Q2UY09-2 Q2UY09-3

Explore the universe of human proteins at neXtProt for COL28A1: NX_Q2UY09

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q2UY09

COL28A1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001032852.2

ENSEMBL proteins:

ENSP00000413093 ENSP00000391380 ENSP00000382356 ENSP00000408401 ENSP00000410557

Reactome Protein details: Q2UY09
Human Recombinant Protein Products for COL28A1:

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	Uscn Proteins for COL28A1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005581	collagen	IEA	--
GO:0005604	basement membrane	IEA	--
GO:0005788	endoplasmic reticulum lumen	TAS	--

COL28A1 for ontologies About GeneDecksing

COL28A1 Antibody Products:

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	Uscn ELISAs and CLIAs for COL28A1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

COL28A1 for domains About GeneDecksing

4 InterPro domains/families:

IPR002223 Prot_inh_Kunz-m

IPR020901 Prtase_inh_Kunz-CS

IPR008160 Collagen

IPR002035 VWF_A

Graphical View of Domain Structure for InterPro Entry Q2UY09

ProtoNet protein and cluster: Q2UY09

2 Blocks protein families:

IPB008160 Collagen triple helix repeat

IPB008161 Collagen helix repeat

UniProtKB/Swiss-Prot: COSA1_HUMAN, Q2UY09

Similarity: Belongs to the VWA-containing collagen family

Similarity: Contains 1 BPTI/Kunitz inhibitor domain

Similarity: Contains 6 collagen-like domains

Similarity: Contains 2 VWFA domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: COSA1_HUMAN, Q2UY09

Function: May act as a cell-binding protein

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004867	serine-type endopeptidase inhibitor activity	IEA	--

COL28A1 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for COL28A1

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL28A1
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL28A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL28A1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL28A1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Collagen formation

	Collagen formation	1.00			Extracellular matrix organization	0.54
	Collagen biosynthesis and modifying enzymes	0.74			Secretion of collagens	0.49

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for COL28A1

	Extracellular matrix organization
	Secretion of collagens
	Collagen biosynthesis and modifying enzymes
	Collagen formation

COL28A1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for COL28A1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/41 Interacting proteins for COL28A1 (ENSP00000382356⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 41)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COL10A1	ENSP00000243222⁴	STRING: ENSP00000243222
COL11A1	ENSP00000351163⁴	STRING: ENSP00000351163
COL13A1	ENSP00000348695⁴	STRING: ENSP00000348695
COL15A1	ENSP00000364140⁴	STRING: ENSP00000364140
COL16A1	ENSP00000362776⁴	STRING: ENSP00000362776

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	IEA	--
GO:0030198	extracellular matrix organization	TAS	--

COL28A1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for COL28A1
Search CenterWatch for drugs/clinical trials and news about COL28A1 / COSA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for COL28A1 gene:

NM_001037763.2

Unigene Cluster for COL28A1:

Collagen, type XXVIII, alpha 1

Hs.491104 [show with all ESTs]

Unigene Representative Sequence: BC144431

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000430711 ENST00000453441 ENST00000399429(uc003src.1 uc011jxe.1)

ENST00000444268(uc003srd.3) ENST00000465339 ENST00000435823(uc003sre.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL28A1
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL28A1 (see all 4) OriGene shRNA RFP: COL28A1 OriGene siRNA: COL28A1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL28A1
		Sirion Biotech Custom design and validation of potent shRNA sequences against COL28A1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL28A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL28A1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: COL28A1 (NM_001037763)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL28A1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL28A1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL28A1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL28A1

Additional cDNA sequence:

AJ890451.1 AJ890452.1 BC063866.1 BC136892.1 BC144431.1

5 DOTS entries:

DT.40127901 DT.75118966 DT.75140475 DT.97769621 DT.75200318

2 AceView cDNA sequences:

BQ723483 BQ888940

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

COL28A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAACTCTA

About this image

COL28A1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See COL28A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COL28A1

SOURCE GeneReport for Unigene cluster: Hs.491104

SABiosciences Custom PCR Arrays for COL28A1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL28A1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL28A1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL28A1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for COL28A1 gene from 3/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	COL28A1¹	collagen, type XXVIII, alpha 1	63.08(n) 55.52(a)		420576 XM_418677.2 XP_418677.2
lizard (Anolis carolinensis)	Reptilia	COL28A1⁶	--	60(a)	1 ↔ 1	6(23589408-23655944)
zebrafish (Danio rerio)	Actinopterygii	LOC100332225¹	collagen alpha-1(XXVIII) chain-like	56.85(n) 50.24(a)		100332225 XM_002665030.2 XP_002665076.2

ENSEMBL Gene Tree for COL28A1 (if available)
TreeFam Gene Tree for COL28A1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for COL28A1 gene

COL6A1² COL6A6² COL6A2² COL6A5² COL6A3²

18/21 SIMAP similar genes for COL28A1 using alignment to 3 protein entries: COSA1_HUMAN (see all proteins) (see all similar genes):

PAPLN ITIL COL21A1 TFPI2 SPINT3 TFPI

APLP2 SPINT1 SPINT4 SPINT2 C1QTNF9 C1QTNF9B

COL25A1 COL10A1 COL3A1 COL9A2 COL1A2 COL5A1

COL28A1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs77601612^1,2	F	--	7397758(+)	`CGACTC/GCTATC`	1	--	ds500¹		1		WA	118
rs183745237^1,2		--	7397776(+)	`TCCTGC/TGTAAA`	1	--	ds500¹		0	--	--	--	--
rs977432^1,2	C,F,H	--	7397843(+)	`TACTGT/CGAGGG`	1	--	ds500¹		28		MN NS EA NA WA CSA	2347
rs145440121^1,2		--	7397863(+)	`GGTTAA/GGGAGG`	1	--	ds500¹		0	--	--	--	--
rs73345208^1,2	C	--	7397921(+)	`ACATAG/ATACAT`	1	--	ds500¹		2		WA	120
rs111635750^1,2		--	7397925(+)	`AGTACG/ATACAA`	1	--	ds500¹		1		CSA	2
rs79887999^1,2	F	--	7397927(+)	`TACATA/GCAACA`	1	--	ds500¹		1		NA	120
rs114924592^1,2	F	--	7398046(+)	`GGGTGA/GCAGTT`	1	--	ds500¹		1		WA	118
rs12155291^1,2	C,H	--	7398110(+)	`AATAAT/GATGTA`	1	--	ds500¹		4		NS EA	420
rs115946113^1,2	F	--	7398153(+)	`TGTATA/CAGTTG`	1	--	ds500¹		1		WA	118

HapMap Linkage Disequilibrium report for COL28A1 (7395834 - 7575484 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for COL28A1
8 CNVs: 99857 9044 8546 64750 2099 2674 3663 94362
2 Indels: 47393 12906

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COL28A1

DNA2.0 Custom Variant and Variant Library Synthesis for COL28A1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

COL28A1 for disorders About MalaCards

COL28A1 for disorders About GeneDecksing

OMIM gene information: 609996 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: COL28A1 (4 documents)

Export disorders for COL28A1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for COL28A1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with COL28A1)

Utopia: connect your pdf to the dynamic
world of online information

Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain. (PubMed id 16330543)^{1, 2, 3, 9} Veit G.... Wagener R. (2006)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{1, 2} Scherer S.W.... Tsui L.-C. (2003)
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)¹ Kennedy R.B....Poland G.A. (2012)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
A genome-wide meta-analysis identifies novel loci ass ociated with schizophrenia and bipolar disorder. (PubMed id 20889312)¹ Wang K.S....Aragam N. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)² Hillier L.W.... Wilson R.K. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 340267	HGNC: 22442	AceView: LOC340267	Ensembl:ENSG00000215018	euGenes: HUgn340267
ECgene: COL28A1	H-InvDB: COL28A1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for COL28A1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for COL28A1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for COL28A1 gene:
Search GeneIP for patents involving COL28A1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COL28A1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COL28A1
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Search for Antibodies & Assays

	Regulatory tfbs in COL28A1 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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COL28A1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for COL28A1

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Search ThermoFisher Antibodies for COL28A1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL28A1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for COL28A1

Sirion Biotech Customized:

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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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COL28A1 Gene

collagen, type XXVIII, alpha 1

Aliases
for COL28A1 gene

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COL28A1 Gene

collagen, type XXVIII, alpha 1

Aliasesfor COL28A1 gene

Summariesfor COL28A1 gene

Genomic Viewsfor COL28A1 gene

Proteinsfor COL28A1 gene

Protein Domains /Familiesfor COL28A1 gene

Functionfor COL28A1 gene

Pathways & Interactionsfor COL28A1 gene

Drugs & Compoundsfor COL28A1 gene

Transcriptsfor COL28A1 gene

Expression for COL28A1 gene

Orthologsfor COL28A1 gene

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Genomic Variantsfor COL28A1 gene

Disorders / Diseasesfor COL28A1 gene

Publicationsfor COL28A1 gene

External Searches for COL28A1 gene

Genome Databases showing COL28A1 gene

Other Databases showing COL28A1 gene

Specialized Databases showing COL28A1 gene

Intellectual Propertyfor COL28A1 gene

Productsfor COL28A1 gene

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Aliases
for COL28A1 gene

Summaries
for COL28A1 gene

Genomic Views
for COL28A1 gene

Proteins
for COL28A1 gene

Protein Domains /
Families
for COL28A1 gene

Function
for COL28A1 gene

Pathways & Interactions
for COL28A1 gene

Drugs & Compounds
for COL28A1 gene

Transcripts
for COL28A1 gene

Expression
for COL28A1 gene

Orthologs
for COL28A1 gene

Paralogs
for COL28A1 gene

Genomic Variants
for COL28A1 gene

Disorders / Diseases
for COL28A1 gene

Publications
for COL28A1 gene

Intellectual Property
for COL28A1 gene

Products
for COL28A1 gene