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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

COL24A1 Gene

protein-coding GIFtS: 48
GCID: GC01M086194

collagen, type XXIV, alpha 1

Search for COL24A1
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Collagen, Type XXIV, Alpha 1¹ ²
Collagen Alpha-1(XXIV) Chain²

External Ids:	HGNC: 20821¹	Entrez Gene: 255631²	Ensembl: ENSG00000171502⁷	OMIM: 610025⁵	UniProtKB: Q17RW2³

Export aliases for COL24A1 gene to outside databases

Previous GC identifers: GC01M086610 GC01M085351 GC01M085487 GC01M085617 GC01M085906 GC01M084305

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: COOA1_HUMAN, Q17RW2

Function: May participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal

development

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the COL24A1 gene promoter:
CRE-BP1 CREB AP-1 deltaCREB ATF-2 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: COL24A1 promoter sequence

Search SABiosciences Chromatin IP Primers for COL24A1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COL24A1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22.3 Ensembl cytogenetic band: 1p22.3 HGNC cytogenetic band: 1p22.3-p22.2

COL24A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL24A1 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M086194: view genomic region (about GC identifiers)

Start:	86,194,916 bp from pter	End:	86,622,626 bp from pter
Size:	427,711 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: COOA1_HUMAN, Q17RW2 (See protein sequence)

Recommended Name: Collagen alpha-1(XXIV) chain precursor

Size: 1714 amino acids; 175496 Da

Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)

Secondary accessions: C9J1X6 Q14BD7 Q59EX5 Q5VY50 Q7Z5L5

Alternative splicing: 2 isoforms: Q17RW2-1 Q17RW2-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COL24A1: NX_Q17RW2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q17RW2

COL24A1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_690850.2

ENSEMBL proteins:

ENSP00000359603 ENSP00000409515 ENSP00000432605 ENSP00000434740 ENSP00000392531

Reactome Protein details: Q17RW2
Human Recombinant Protein Products:

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	GenScript Custom Purified and Recombinant Proteins Services for COL24A1
	Novus Biologicals COL24A1 Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005581	collagen	IEA	--
GO:0005788	endoplasmic reticulum lumen	TAS	--

COL24A1 for ontologies About GeneDecksing

COL24A1 Antibody Products:

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	Novus Biologicals COL24A1 Antibodies
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Assay Products for COL24A1:

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	GenScript Custom Assay Services for COL24A1
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

COL24A1 for domains About GeneDecksing

5 InterPro domains/families:

IPR013320 ConA-like_subgrp

IPR001791 Laminin_G

IPR000885 Fib_collagen_C

IPR008160 Collagen

IPR008985 ConA-like_lec_gl_sf

Graphical View of Domain Structure for InterPro Entry Q17RW2

ProtoNet protein and cluster: Q17RW2

3 Blocks protein families:

IPB003129 Thrombospondin

IPB008160 Collagen triple helix repeat

IPB008161 Collagen helix repeat

UniProtKB/Swiss-Prot: COOA1_HUMAN, Q17RW2

Similarity: Belongs to the fibrillar collagen family

Similarity: Contains 17 collagen-like domains

Similarity: Contains 1 fibrillar collagen NC1 domain

Similarity: Contains 1 laminin G-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: COOA1_HUMAN, Q17RW2

Function: May participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal

development

miRNA Products:		OriGene 3'-UTR Clone: COL24A1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL24A1
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate COL24A1 (see all 38):
		hsa-miR-411* hsa-miR-379* hsa-let-7d hsa-miR-15a hsa-miR-29a hsa-miR-16-1* hsa-miR-374a hsa-miR-766

		SwitchGear 3'UTR luciferase reporter plasmid: COL24A1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL24A1 (see all 4) OriGene shRNA RFP: COL24A1 OriGene siRNA: COL24A1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL24A1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for COL24A1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL24A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL24A1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: COL24A1 (NM_152890)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL24A1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL24A1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for COL24A1
		Search LifeMap BioReagents cell lines for COL24A1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL24A1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005201	extracellular matrix structural constituent	IEA	--

COL24A1 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for COL24A1:

Cell cycle / mitosis defect

Synthetic lethal with Ras

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Integrin Pathway

Integrin Pathway	1.00	UPA-UPAR Pathway	0.51
FAK1 Signaling	0.67	Transendothelial Migration of Leukocytes	0.38
GnRH Signaling	0.56	Inhibition of Angiogenesis by TSP1	0.37

Collagen formation

Collagen formation	1.00	Extracellular matrix organization	0.54
Collagen biosynthesis and modifying enzymes	0.74	Secretion of collagens	0.49
Assembly of collagen fibrils and other multimeric structures	0.65

Rho Family GTPases

Rho Family GTPases	1.00	MAPK Signaling	0.51
ERK Signaling	0.61	ILK Signaling	0.45
Molecular Mechanisms of Cancer	0.51

Formation of collagen fibres

Formation of collagen fibrils

1.00

Formation of collagen fibres

1.00

Blood Coagulation Cascade

Blood Coagulation Cascade

1.00

Intrinsic Prothrombin Activation Pathway

0.96

Pathway sources
See GeneCards unified pathways
Show all pathways

5/15 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for COL24A1 (see all 15)

	MAPK Signaling
	Molecular Mechanisms of Cancer
	PTEN Pathway
	Transendothelial Migration of Leukocytes
	UPA-UPAR Pathway

1 BioSystems Pathway for COL24A1

ATF-2 transcription factor network

5/7 Reactome Pathways for COL24A1 (see all 7)

	Extracellular matrix organization
	Formation of collagen fibrils
	Secretion of collagens
	Collagen biosynthesis and modifying enzymes
	Assembly of collagen fibrils and other multimeric structures

COL24A1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for COL24A1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/41 Interacting proteins for COL24A1 (ENSP00000359603⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 41)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COL10A1	ENSP00000243222⁴	STRING: ENSP00000243222
COL11A1	ENSP00000351163⁴	STRING: ENSP00000351163
COL13A1	ENSP00000348695⁴	STRING: ENSP00000348695
COL15A1	ENSP00000364140⁴	STRING: ENSP00000364140
COL18A1	ENSP00000352798⁴	STRING: ENSP00000352798

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030198	extracellular matrix organization	TAS	--

COL24A1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for COL24A1
Search CenterWatch for drugs/clinical trials and news about COL24A1 / COOA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for COL24A1 gene:

NM_152890.5

Unigene Cluster for COL24A1:

Collagen, type XXIV, alpha 1

Hs.659516 [show with all ESTs]

Unigene Representative Sequence: NM_152890

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000370571(uc001dlj.3 uc010osd.2 uc001dlk.3 uc010ose.2 uc010osf.2)

ENST00000426639(uc009wcq.3) ENST00000473734 ENST00000496682 ENST00000485434

ENST00000436319(uc001dli.3)

miRNA Products:		OriGene 3'-UTR Clone: COL24A1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL24A1
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate COL24A1 (see all 38):
		hsa-miR-411* hsa-miR-379* hsa-let-7d hsa-miR-15a hsa-miR-29a hsa-miR-16-1* hsa-miR-374a hsa-miR-766

		SwitchGear 3'UTR luciferase reporter plasmid: COL24A1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL24A1 (see all 4) OriGene shRNA RFP: COL24A1 OriGene siRNA: COL24A1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL24A1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL24A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL24A1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: COL24A1 (NM_152890)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL24A1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL24A1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL24A1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat COL24A1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL24A1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL24A1

Additional cDNA sequence:

AB209686.1 AK094856.1 AK308953.1 AY244357.1 BC113654.1 BC116180.2 BC117170.1 BC143715.1

BC143717.1 BC143718.1

5 DOTS entries:

DT.100017143 DT.101975337 DT.433339 DT.405091 DT.99936094

24/28 AceView cDNA sequences (see all 28):

BM145695 AK094856 CD638152 AW468746 CD638156 NM_152890 CD638155 AA331798

CA390114 AY244357 BF109117 CD638151 CD638158 AI631241 CD638161 CD638148

BI494243 N51674 AI240366 AI445501 CD638167 AI039103 BM148596 CD638146

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for COL24A1 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20	^	21	^	22	^	23	^	24	^	25	^
SP1:
SP2:
SP3:
SP4:							-

ExUns:	26	^	27	^	28	^	29	^	30	^	31	^	32	^	33	^	34	^	35	^	36	^	37a	·	37b	^	38	^	39	^	40a	·	40b	^	41
SP1:																													-
SP2:
SP3:
SP4:

ECgene alternative splicing isoforms for COL24A1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

COL24A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

COL24A1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Zeugopod Epiphyseal End

Chondrocytes

Bone, Cartilage

Bone

Thoracic Rib

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor W10 (Embryonic Progenitor Cell)

See COL24A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COL24A1

SOURCE GeneReport for Unigene cluster: Hs.659516

SABiosciences Custom PCR Arrays for COL24A1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL24A1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat COL24A1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL24A1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL24A1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL24A1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for COL24A1 gene from 2/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	COL24A1¹	collagen, type XXIV, alpha 1	70.43(n) 66.1(a)		424526 XM_422363.3 XP_422363.3
zebrafish (Danio rerio)	Actinopterygii	col27a1a⁶ si:dkey-117n7.4⁶	si:dkey-117n7.4	29(a) 29(a)	possible ortholog possible ortholog	16(55373410-55517762) 4(15019685-15029422)

ENSEMBL Gene Tree for COL24A1 (if available)
TreeFam Gene Tree for COL24A1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for COL24A1 gene

COL4A6² COL19A1² COL11A2² COL4A5² COL4A4² COL5A3² COL1A1² COL16A1²

COL4A2² COL5A2² COL5A1² COL4A3² COL22A1² COL7A1² COL1A2² COL27A1²

COL2A1² COL3A1² COL4A1² COL11A1²

18/26 SIMAP similar genes for COL24A1 using alignment to 4 protein entries: COOA1_HUMAN (see all proteins) (see all similar genes):

AURA2 LINC00596 FAM3A ZNF564 NF2 EIF3L

FAM175A SHANK2 APOD DNAPTP3 SEPT2 UTY

CRCP COL27A1 GLT8D2 ZNF74 COL17A1 COL6A2

COL24A1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs7529764^1,2	C,F,H,	--	86194437(+)	`attgaG/Aagagt`	1	--	ds500¹		15		NS EA NA WA	2030
rs189722089^1,2		--	86194598(+)	`AGTTAC/TTTTTT`	1	--	ds500¹		0	--	--	--	--
rs113905069^1,2	C,	--	86194634(+)	`CCATCC/ATTCTT`	1	--	ds500¹		1		CSA	2
rs192865042^1,2		--	86194649(+)	`ATGTGA/GATATC`	1	--	ds500¹		0	--	--	--	--
rs184545108^1,2		--	86194815(+)	`CTTAAC/TAATAT`	1	--	ds500¹		0	--	--	--	--
rs139087729^1,2		--	86194948(+)	`TAGGTC/TAAGTG`	1	--	ut3¹		0	--	--	--	--
rs116000878^1,2	F,	--	86194977(+)	`GATATA/GTTTAT`	1	--	ut3¹		1		WA	118
rs1047895^1,2	C,F,O,A,H,	--	86194997(-)	`GAAAAG/ACTTGT`	1	--	ut3¹		19		MN NS EA NA WA	2520
rs1047893^1,2	C,F,A,H,	--	86195047(-)	`GAAATA/GTTAGT`	1	--	ut3¹		22		MN NS EA NA WA CSA	2528
rs1047892^1,2	C,F,A,H,	--	86195066(-)	`ATGTCT/GCCTTG`	1	--	ut3¹ ese³		23		MN NS EA NA WA CSA	2521

HapMap Linkage Disequilibrium report for COL24A1 (86194916 - 86444916 bp, first 250kb of COL24A1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 16 variations for COL24A1
8 CNVs: 31631 64138 58412 1317 1544 84351 97431 43547
8 Indels: 39633 39632 44643 24284 64129 60854 42596 59939

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COL24A1

DNA2.0 Custom Variant and Variant Library Synthesis for COL24A1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

COL24A1 for disorders About MalaCards

COL24A1 for disorders About GeneDecksing

OMIM gene information: 610025 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: COL24A1 (4 documents)

Export disorders for COL24A1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for COL24A1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with COL24A1)

Utopia: connect your pdf to the dynamic
world of online information

Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone. (PubMed id 12874293)^{1, 2} Koch M.... Gordon M.K. (2003)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
CREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblasts. (PubMed id 16373341)¹ Matsuo N.... Ramirez F. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 255631	HGNC: 20821	AceView: COL24A1	Ensembl:ENSG00000171502	euGenes: HUgn255631
ECgene: COL24A1	H-InvDB: COL24A1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for COL24A1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for COL24A1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for COL24A1 gene:
Search GeneIP for patents involving COL24A1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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COL24A1 Gene

collagen, type XXIV, alpha 1

Aliases
for COL24A1 gene

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COL24A1 Gene

collagen, type XXIV, alpha 1

Aliasesfor COL24A1 gene

Summariesfor COL24A1 gene

Genomic Viewsfor COL24A1 gene

Proteinsfor COL24A1 gene

Protein Domains /Familiesfor COL24A1 gene

Functionfor COL24A1 gene

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Expression for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

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for COL24A1 gene

Expression
for COL24A1 gene

Orthologs
for COL24A1 gene

Paralogs
for COL24A1 gene

Genomic Variants
for COL24A1 gene

Disorders / Diseases
for COL24A1 gene

Publications
for COL24A1 gene

Intellectual Property
for COL24A1 gene

Products
for COL24A1 gene