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COL23A1 Gene

protein-coding   GIFtS: 52
GCID: GC05M177664

Collagen, Type XXIII, Alpha 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Collagen, Type XXIII, Alpha 11 2
Collagen Alpha-1(XXIII) Chain2
Procollagen, Type XXIII, Alpha 12

External Ids:    HGNC: 229901   Entrez Gene: 915222   Ensembl: ENSG000000507677   OMIM: 6100435   UniProtKB: Q86Y223   

Export aliases for COL23A1 gene to outside databases

Previous GC identifers: GC05M177733 GC05M177778 GC05M177597 GC05M172390


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for COL23A1 Gene:
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a
single pass hydrophobic transmembrane domain (Banyard et al., 2003 (PubMed 12644459)).(supplied by OMIM, Mar
2008)

GeneCards Summary for COL23A1 Gene:
COL23A1 (collagen, type XXIII, alpha 1) is a protein-coding gene. An important paralog of this gene is COL25A1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_023133.14  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the COL23A1 gene promoter:
         HFH-3   SRF   ISGF-3   AP-1   SRF (504 AA)   MyoD   RORalpha2   FOXI1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): COL23A1 promoter sequence
   Search Chromatin IP Primers for COL23A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COL23A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

COL23A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL23A1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M177664:  view genomic region     (about GC identifiers)

Start:
177,664,617 bp from pter      End:
178,017,556 bp from pter
Size:
352,940 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CONA1_HUMAN, Q86Y22 (See protein sequence)
Recommended Name: Collagen alpha-1(XXIII) chain  
Size: 540 amino acids; 51944 Da
Subunit: Homotrimer (By similarity)
Secondary accessions: Q8IVR4 Q9NT93
Alternative splicing: 2 isoforms:  Q86Y22-1   Q86Y22-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COL23A1: NX_Q86Y22

Explore proteomics data for COL23A1 at MOPED

Post-translational modifications: 

  • Undergoes proteolytic cleavage by furin protease to yield a 60 kDa soluble form that forms a homotrimer and
    exhibits a low affinity interaction with heparin (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See COL23A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_775736.2  
    ENSEMBL proteins: 
     ENSP00000375069   ENSP00000385092  
    Reactome Protein details: Q86Y22

    COL23A1 Human Recombinant Protein Products:

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    Novus Biologicals COL23A1 Proteins
    Novus Biologicals COL23A1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for COL23A1 

     
    antibodies-online proteins for COL23A1 (5 products) 

     
    antibodies-online peptides for COL23A1

    COL23A1 Antibody Products:

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    antibodies-online antibodies for COL23A1 (10 products) 

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    antibodies-online kits for COL23A1 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    COLLAGEN: Collagens

    1 InterPro protein domain:
     IPR008160 Collagen

    Graphical View of Domain Structure for InterPro Entry Q86Y22

    ProtoNet protein and cluster: Q86Y22

    2 Blocks protein domains:
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: CONA1_HUMAN, Q86Y22
    Similarity: Contains 5 collagen-like domains


    Find genes that share domains with COL23A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         2 GenomeRNAi human phenotypes for COL23A1:
     Increased S DNA content  Increased number of mitotic ce 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for COL23A1

    miRNA
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    Block miRNA regulation of human, mouse, rat COL23A1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate COL23A1 (see all 17):
    hsa-miR-3934 hsa-miR-2052 hsa-miR-16-2* hsa-miR-19b-2* hsa-miR-125a-3p hsa-miR-520d-5p hsa-let-7a-2* hsa-miR-512-3p
    SwitchGear 3'UTR luciferase reporter plasmidCOL23A1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for COL23A1
    Predesigned siRNA for gene silencing in human, mouse, rat COL23A1

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    GenScript: all cDNA clones in your preferred vector: COL23A1 (NM_173465)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL23A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL23A1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL23A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CONA1_HUMAN, Q86Y22: Cell membrane; Single-pass type II membrane protein; Extracellular side (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum4
    extracellular3
    cytosol1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen IEA--
    GO:0005788endoplasmic reticulum lumen TAS--
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with COL23A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for COL23A1 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1Collagen biosynthesis and modifying enzymes
    Collagen biosynthesis and modifying enzymes0.75
    Intrinsic Prothrombin Activation Pathway0.39
    Collagen formation0.75
    Blood Coagulation Cascade0.38
    2Integrin Pathway
    FAK1 Signaling0.67
    UPA-UPAR Pathway0.56
    Integrin Pathway0.67
    Inhibition of Angiogenesis by TSP10.50
    GnRH Signaling0.56
    Transendothelial Migration of Leukocytes0.38
    3ERK Signaling
    Rho Family GTPases0.61
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    ILK Signaling0.49
    MAPK Signaling0.58
    4Degradation of the extracellular matrix
    Degradation of the extracellular matrix0.43
    Extracellular matrix organization0.34
    Collagen degradation0.43
    5Phospholipase-C Pathway
    Phospholipase-C Pathway0.56
    PTEN Pathway0.56


    Find genes that share SuperPaths with COL23A1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for COL23A1 (see all 15)
        MAPK Signaling
    Molecular Mechanisms of Cancer
    PTEN Pathway
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway

    3 Reactome Pathways for COL23A1
        Integrin cell surface interactions
    Collagen biosynthesis and modifying enzymes
    Collagen degradation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COL23A1
    Interactions:

        Search GeneGlobe Interaction Network for COL23A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for COL23A1 (Q86Y223 ENSP000003750694) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FURINP099583, ENSP000002681714I2D: score=1 STRING: ENSP00000268171
    LSM8O957773, ENSP000002492994I2D: score=4 STRING: ENSP00000249299
    COL10A1ENSP000002432224STRING: ENSP00000243222
    COL11A1ENSP000003511634STRING: ENSP00000351163
    COL12A1ENSP000003251464STRING: ENSP00000325146
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022617extracellular matrix disassembly TAS--
    GO:0030198extracellular matrix organization TAS--
    GO:0030574collagen catabolic process TAS--

    Find genes that share ontologies with COL23A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COL23A1 (CONA1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for COL23A1 gene: 
    NM_173465.3  

    Unigene Cluster for COL23A1:

    Collagen, type XXIII, alpha 1
    Hs.660026  [show with all ESTs]
    Unigene Representative Sequence: NM_173465
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000390654(uc010jkt.2 uc021yiy.1 uc021yiz.1) ENST00000484750
    ENST00000407622
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate COL23A1 (see all 17):
    hsa-miR-3934 hsa-miR-2052 hsa-miR-16-2* hsa-miR-19b-2* hsa-miR-125a-3p hsa-miR-520d-5p hsa-let-7a-2* hsa-miR-512-3p
    SwitchGear 3'UTR luciferase reporter plasmidCOL23A1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat COL23A1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat COL23A1
      QuantiTect SYBR Green Assays in human, mouse, rat COL23A1
      QuantiFast Probe-based Assays in human, mouse, rat COL23A1

    Additional mRNA sequence: 

    AL137461.1 AY158895.1 AY898961.1 

    5 DOTS entries:

    DT.100740250  DT.406862  DT.75125190  DT.95249322  DT.91842038 

    2 AceView cDNA sequences:

    AI420126 BV191746 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for COL23A1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                              
    SP2:        -                                                                                                                     
    SP3:                                                                                                                              
    SP4:                                                                                                                              
    SP5:              -                                                                                                               


    ECgene alternative splicing isoforms for COL23A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    COL23A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    COL23A1 Expression
    About this image


    COL23A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Kidney (Urinary System)    fully expand to see all 4 entries
             Ureteric Bud Cells Ureteric Bud
             Metanephros
     
     Primitive Streak (Early Embryonic Tissues)
             Primitive streak-like cells
     
     Lower Urinary Tract (Urinary System)
             Ureter
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
    COL23A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COL23A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.660026
        Custom PCR Arrays for COL23A1
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL23A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for COL23A1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Col23a11 , 5 collagen, type XXIII, alpha 11, 5 86.34(n)1
    92.75(a)1
      11 (31.03 cM)5
    2377591  NM_153393.21  NP_700442.21 
     512899205 
    chicken
    (Gallus gallus)
    Aves COL23A11 collagen, type XXIII, alpha 1 68.82(n)
    78.23(a)
      425481  XM_003642083.2  XP_003642131.2 
    lizard
    (Anolis carolinensis)
    Reptilia COL23A16
    collagen, type XXIII, alpha 1
    51(a)
    1 ↔ 1
    2(141956730-142011862)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018862661 collagen alpha-1(XXIII) chain-like 61.51(n)
    63.32(a)
      101886266  XM_005161400.1  XP_005161457.1 
    worm
    (Caenorhabditis elegans)
    Secernentea col-1356
    Protein COL-135, isoform a (col-135) mRNA, complet...
    27(a)
    1 → many
    IV(15129662-15131786) WBGene00000708


    ENSEMBL Gene Tree for COL23A1 (if available)
    TreeFam Gene Tree for COL23A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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    Paralogs for COL23A1 gene
    COL25A12  COL19A12  COL9A12  COL22A12  COL13A12  COL9A32  COL9A22  COL16A12  
    COL21A12  
    3 SIMAP similar genes for COL23A1 using alignment to 2 protein entries:     CONA1_HUMAN (see all proteins):
    COL11A1    COL11A2    FCN2

    Find genes that share paralogs with COL23A1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for COL23A1 (see all 8844)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1409379121,2
    Cuntested1177689227(+) TCGCCA/G/TTCTTG 2 E D mis10--------
    rs1841129971,2
    --177664130(+) GGCACA/CCATCA 1 -- int10--------
    rs1463467831,2
    C--177664165(+) TTCTTC/TACTTT 1 -- int10--------
    rs1381330611,2
    --177664210(+) GGTCTC/TGAACT 1 -- int10--------
    rs1175497501,2
    C,F--177664223(+) TGGGCT/CCAAGT 1 -- int11Minor allele frequency- C:0.03EA 120
    rs1866409821,2
    --177664244(+) CCTTGC/TCCTCC 1 -- int10--------
    rs77157621,2
    C,F,A,H--177664297(+) aaatcG/Accatt 1 -- int116Minor allele frequency- A:0.13NS EA NA WA 2210
    rs1918872431,2
    --177664364(+) TAGAGA/GAGCAC 1 -- int10--------
    rs1823947521,2
    --177664375(+) ACAGGA/GGCTCA 1 -- int10--------
    rs1495715491,2
    --177664623(+) AGACAC/TGCACT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for COL23A1 (177664617 - 177914617 bp, first 250kb of COL23A1)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for COL23A1 (see all 93):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1948375CNV Deletion18987734
    esv2731222CNV Deletion23290073
    esv3220CNV Deletion18987735
    esv2731261CNV Deletion23290073
    esv2605116CNV Deletion19546169
    esv2731234CNV Deletion23290073
    esv2731223CNV Deletion23290073
    esv2731249CNV Deletion23290073
    nsv820848CNV Deletion20802225
    esv2731248CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610043    OMIM disorders: --

    2 diseases from the University of Copenhagen DISEASES database for COL23A1:
    Hypertrichosis     Spina bifida

    Find genes that share disorders with COL23A1           About GenesLikeMe

    Genetic Association Database (GAD): COL23A1
    Human Genome Epidemiology (HuGE) Navigator: COL23A1 (4 documents)

    Export disorders for COL23A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for COL23A1 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with COL23A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Type XXIII collagen, a new transmembrane collagen identified in metastatic tumor cells. (PubMed id 12644459)1, 2, 3 Banyard J.... Zetter B.R. (J. Biol. Chem. 2003)
    2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    5. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (Int J Eat Disord 2013)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. Collagen XXIII, novel ligand for integrin alpha2beta1 in the epidermis. (PubMed id 21652699)1 Veit G....Koch M. (J. Biol. Chem. 2011)
    10. Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer. (PubMed id 20447926)1 Spivey K.A....Zetter B.R. (amp 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 91522 HGNC: 22990 AceView: COL23A1.1 Ensembl:ENSG00000050767 euGenes: HUgn91522
    ECgene: COL23A1 H-InvDB: COL23A1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for COL23A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for COL23A1 gene:
    Search GeneIP for patents involving COL23A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    Advanced Cell Diagnostics, Animal models from genOway)
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