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COL20A1 Gene

protein-coding   GIFtS: 52
GCID: GC20P061924

Collagen, Type XX, Alpha 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Collagen, Type XX, Alpha 11 2
bA261N11.42
Collagen Alpha-1(XX) Chain2
Collagen-Like Protein2
KIAA15103

External Ids:    HGNC: 146701   Entrez Gene: 576422   Ensembl: ENSG000001012037   UniProtKB: Q9P2183   

Export aliases for COL20A1 gene to outside databases

Previous GC identifers: GC20P061398 GC20P058649


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for COL20A1 Gene:
COL20A1 (collagen, type XX, alpha 1) is a protein-coding gene. Diseases associated with COL20A1 include kidney disease, and atherosclerosis. An important paralog of this gene is VWA1.

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218
Function: Probable collagen protein




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the COL20A1 gene promoter:
         STAT5B   ATF-2   STAT5A   Ik-3   LCR-F1   CREB   IRF-7A   c-Jun   MRF-2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOL20A1 promoter sequence
   Search Chromatin IP Primers for COL20A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat COL20A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

COL20A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL20A1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P061924:  view genomic region     (about GC identifiers)

Start:
61,924,538 bp from pter      End:
61,966,203 bp from pter
Size:
41,666 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218 (See protein sequence)
Recommended Name: Collagen alpha-1(XX) chain precursor  
Size: 1284 amino acids; 135830 Da
Sequence caution: Sequence=AAH19637.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
3 PDB 3D structures from and Proteopedia for COL20A1:
2DKM (3D)        2EE3 (3D)        2EKJ (3D)    
Secondary accessions: Q4VXQ4 Q6PI59 Q8WUT2 Q96CY9 Q9BQU6 Q9BQU7
Alternative splicing: 3 isoforms:  Q9P218-1   Q9P218-2   Q9P218-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COL20A1: NX_Q9P218

Explore proteomics data for COL20A1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn607
  • Modification sites at PhosphoSitePlus

  • See COL20A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065933.2  
    ENSEMBL proteins: 
     ENSP00000351767   ENSP00000414753   ENSP00000410799   ENSP00000406345   ENSP00000323077  
     ENSP00000408690  
    Reactome Protein details: Q9P218

    COL20A1 Human Recombinant Protein Products:

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    Novus Biologicals COL20A1 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    COL20A1 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for COL20A1

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    COLLAGEN: Collagens

    Selected InterPro protein domains (see all 6):
     IPR003961 Fibronectin_type3
     IPR001791 Laminin_G
     IPR013783 Ig-like_fold
     IPR008160 Collagen
     IPR008985 ConA-like_lec_gl_sf

    Graphical View of Domain Structure for InterPro Entry Q9P218

    ProtoNet protein and cluster: Q9P218

    4 Blocks protein domains:
    IPB002035 Von Willebrand factor type A domain signature
    IPB003129 Thrombospondin
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218
    Similarity: Contains 2 collagen-like domains
    Similarity: Contains 6 fibronectin type-III domains
    Similarity: Contains 1 laminin G-like domain
    Similarity: Contains 1 VWFA domain


    COL20A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COKA1_HUMAN, Q9P218
    Function: Probable collagen protein

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    COL20A1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for COL20A1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for COL20A1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for COL20A1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COL20A1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COL20A1

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    GenScript: all cDNA clones in your preferred vector: COL20A1 (NM_020882)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL20A1

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    Browse ESI BIO Cell Lines and PureStem Progenitors for COL20A1 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL20A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COKA1_HUMAN, Q9P218: Secreted, extracellular space (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    extracellular4
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005581collagen IEA--
    GO:0005615extracellular space IEA--
    GO:0005788endoplasmic reticulum lumen TAS--
    GO:0031012colocalizes with extracellular matrix TAS--

    COL20A1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for COL20A1 About    
    See pathways by source

    SuperPathContained pathways About
    1Collagen biosynthesis and modifying enzymes
    Collagen biosynthesis and modifying enzymes0.75
    Collagen formation0.75
    2Degradation of the extracellular matrix
    Extracellular matrix organization0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for COL20A1 (see all 15)
        MAPK Signaling
    Molecular Mechanisms of Cancer
    PTEN Pathway
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway

    1 Reactome Pathway for COL20A1
        Collagen biosynthesis and modifying enzymes



    COL20A1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for COL20A1
    Interactions:

        Search GeneGlobe Interaction Network for COL20A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for COL20A1 (Q9P2183 ENSP000003517674) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TEX11Q8IYF33, ENSP000003409954I2D: score=4 STRING: ENSP00000340995
    PDZD3Q86UT53I2D: score=1 
    COL12A1ENSP000003251464STRING: ENSP00000325146
    COL13A1ENSP000003486954STRING: ENSP00000348695
    COL14A1ENSP000002978484STRING: ENSP00000297848
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030198extracellular matrix organization TAS--

    COL20A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for COL20A1 (COKA1)

    4 Novoseek inferred chemical compound relationships for COL20A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hydroxylysine 79.3 2 12444623 (1), 8268829 (1)
    hydroxyproline 46.7 2 15528200 (1), 8268829 (1)
    gold 1.82 1 2178159 (1)
    tyrosine 0 1 9786938 (1)



    COL20A1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for COL20A1 gene: 
    NM_020882.2  

    Unigene Cluster for COL20A1:

    Collagen, type XX, alpha 1
    Hs.271285  [show with all ESTs]
    Unigene Representative Sequence: AB040943
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358894(uc011aau.2) ENST00000479501 ENST00000422202(uc011aav.2)
    ENST00000415763 ENST00000455906 ENST00000471582 ENST00000494913 ENST00000496810
    ENST00000326996 ENST00000435874
    miRNA
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    Search for qRT-PCR Assays for microRNAs that regulate COL20A1
    SwitchGear 3'UTR luciferase reporter plasmidCOL20A1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for COL20A1
    Predesigned siRNA for gene silencing in human, mouse, rat COL20A1
    Clone
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    OriGene clones in human, mouse for COL20A1 (see all 7)
    OriGene ORF clones in mouse, rat for COL20A1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: COL20A1 (NM_020882)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL20A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL20A1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for COL20A1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat COL20A1
      QuantiTect SYBR Green Assays in human, mouse, rat COL20A1
      QuantiFast Probe-based Assays in human, mouse, rat COL20A1

    Additional mRNA sequence: 

    AB040943.1 AK098702.1 AL390141.1 BC013658.1 BC019637.1 BC041767.1 BC043183.1 

    6 DOTS entries:

    DT.91651030  DT.100751911  DT.100751913  DT.100001519  DT.95216368  DT.100751912 

    Selected AceView cDNA sequences (see all 42):

    BC013658 BF528839 AK098702 AB040943 BC041767 BF345918 BG819225 BG818387 
    Z45774 NM_020882 BF346541 BM548112 BU730454 BF347240 BF527501 AL390141 
    F04648 BC043183 BG820122 BC019637 BM704820 BG912938 BF343607 R19740 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for COL20A1 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b ^ 21 ^
    SP1:                                                                                                                          -                 -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                          -                                 
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27a · 27b ^ 28a · 28b
    SP1:              -                       -                     
    SP2:              -                       -                     
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for COL20A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    COL20A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCATCTTGG
    COL20A1 Expression
    About this image


    COL20A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
     
     Neurons
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer
     
     Brain (Nervous System)
             Oligodendrocyte Precursor Cells Forebrain White Matter
     
     Testis (Reproductive System)
    COL20A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    COL20A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.271285

    UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218
    Tissue specificity: High expression in heart, lung, liver, skeletal muscle, kidney, pancreas, spleen, testis,
    ovary, subthalamic nucleus and fetal liver. Weak expression in other tissues tested

        Custom PCR Arrays for COL20A1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL20A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for COL20A1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Col20a11 , 5 collagen, type XX, alpha 11, 5 76.08(n)1
    72.39(a)1
      2 (103.53 cM)5
    733681  NM_028518.11  NP_082794.11 
     1809865355 
    chicken
    (Gallus gallus)
    Aves COL20A11 collagen, type XX, alpha 1 61.76(n)
    54.95(a)
      419243  NM_001004392.1  NP_001004392.1 
    lizard
    (Anolis carolinensis)
    Reptilia COL20A16
    collagen, type XX, alpha 1
    37(a)
    1 ↔ 1
    4(153541099-153680858)
    African clawed frog
    (Xenopus laevis)
    Amphibia BI442495.12   -- 77.44(n)    BI442495.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc35c26
    solute carrier family 35, member C2
    29(a)
    1 ↔ 1
    23(20719938-20800504) ENSDARG00000037517


    ENSEMBL Gene Tree for COL20A1 (if available)
    TreeFam Gene Tree for COL20A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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    Paralogs for COL20A1 gene
    VWA12  MATN42  COL14A12  MATN32  MATN22  VIT2  COL12A12  COCH2  
    VWA22  MATN12  
    5 SIMAP similar genes for COL20A1 using alignment to 3 protein entries:     COKA1_HUMAN (see all proteins):
    COL12A1    COL7A1    XB    DKFZp434L081    FCN2

    COL20A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for COL20A1 (see all 1310)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1419739431,2
    --61922651(+) GACCCG/TGACGC 1 -- us2k10--------
    rs2002481731,2
    --61922733(+) CGCCC-/GG    
       TGCCT
    GGTGC
    1 -- us2k10--------
    rs1444092611,2
    C--61922742(+) CTGGT-/GCGCCTG 1 -- us2k10--------
    rs48092831,2
    C,F,A--61922918(+) gggtgT/Cggtgg 1 -- us2k13Minor allele frequency- C:0.09NA CSA 124
    rs1872272721,2
    --61922930(+) TCACAC/TCTGTA 1 -- us2k10--------
    rs60903441,2
    C,F,A,H--61922957(+) AGGCCG/AAGGCG 1 -- us2k11Minor allele frequency- A:0.33NA 6
    rs48092841,2
    C,F,H--61923157(+) TTGTTC/TTCTAG 1 -- us2k115Minor allele frequency- T:0.05NS EA NA CSA 1540
    rs1917384371,2
    --61923192(+) ATCTCA/GAGAAA 1 -- us2k10--------
    rs1387491451,2
    --61923355(+) GCCAGC/TGCTGG 1 -- us2k10--------
    rs784328311,2
    C--61923604(+) CAGTGC/GTCCTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COL20A1 (61924538 - 61966203 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for COL20A1 (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1600196CNV Deletion17803354
    esv2722904CNV Deletion23290073
    dgv4632n71CNV Loss21882294
    nsv913165CNV Loss21882294
    dgv4618n71CNV Loss21882294
    nsv913183CNV Loss21882294
    dgv4626n71CNV Loss21882294
    dgv4629n71CNV Loss21882294
    nsv913181CNV Loss21882294
    nsv913177CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing COL20A1
    DNA2.0 Custom Variant and Variant Library Synthesis for COL20A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    3 diseases for COL20A1:    
    About MalaCards
    kidney disease    atherosclerosis    obesity


    COL20A1 for disorders           About GeneDecksing


    Export disorders for COL20A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for COL20A1 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with COL20A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    4. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Design, expression and characterization of collagen-like proteins based on the cell adhesive and crosslinking sequences derived from native collagens. (PubMed id 15632304)9 Yao J....Asakura T. (J. Biochem. 2004)
    7. Testing the utility of rationally engineered recombinant collagen-like proteins for applications in tissue engineering. (PubMed id 16278869)9 Ito H....Fertala A. (J Biomed Mater Res A 2006)
    8. A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. (PubMed id 15647274)9 Humtsoe J.O....Wary K.K. (J. Biol. Chem. 2005)
    9. Prospects and limitations of the rational engineering of fibrillar collagens. (PubMed id 12931004)9 Majsterek I....Fertala A. (Protein Sci. 2003)
    10. Evidence for increased hydroxylation of pyrrolidone amino acid residues in the cuticle of mature Onchocerca volvulus. (PubMed id 9197461)9 Sakwe A.M. and Titanji V.P. (Biochim. Biophys. Acta 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 57642 HGNC: 14670 AceView: KIAA1510 Ensembl:ENSG00000101203 euGenes: HUgn57642
    ECgene: COL20A1 H-InvDB: COL20A1

    (According to HUGE)
    About This Section

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    HUGE: KIAA1510

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for COL20A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for COL20A1 gene:
    Search GeneIP for patents involving COL20A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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