Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

COL20A1 Gene

protein-coding GIFtS: 51
GCID: GC20P061924

collagen, type XX, alpha 1

Explore 5 diseases affiliated with
COL20A1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Collagen, Type XX, Alpha 1¹ ²
KIAA1510¹ ³
BA261N11.4¹
Collagen Alpha-1(XX) Chain²
Collagen-Like Protein²

External Ids:	HGNC: 14670¹	Entrez Gene: 57642²	Ensembl: ENSG00000101203⁷	UniProtKB: Q9P218³

Export aliases for COL20A1 gene to outside databases

Previous GC identifers: GC20P061398 GC20P058649

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218

Function: Probable collagen protein

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011333.6

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the COL20A1 gene promoter:
STAT5B ATF-2 STAT5A Ik-3 LCR-F1 CREB IRF-7A c-Jun MRF-2 ATF6
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: COL20A1 promoter sequence

Search SABiosciences Chromatin IP Primers for COL20A1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COL20A1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33 Ensembl cytogenetic band: 20q13.33 HGNC cytogenetic band: 20q13.33

COL20A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL20A1 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P061924: view genomic region (about GC identifiers)

Start:	61,924,538 bp from pter	End:	61,966,203 bp from pter
Size:	41,666 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218 (See protein sequence)

Recommended Name: Collagen alpha-1(XX) chain precursor

Size: 1284 amino acids; 135830 Da

Subcellular location: Secreted, extracellular space (Probable)

Sequence caution: Sequence=AAH19637.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

3 PDB 3D structures from and Proteopedia for COL20A1:

2DKM (3D)

2EE3 (3D)

2EKJ (3D)

Secondary accessions: Q4VXQ4 Q6PI59 Q8WUT2 Q96CY9 Q9BQU6 Q9BQU7

Alternative splicing: 3 isoforms: Q9P218-1 Q9P218-2 Q9P218-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COL20A1: NX_Q9P218

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9P218

COL20A1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065933.2

ENSEMBL proteins:

ENSP00000351767 ENSP00000414753 ENSP00000410799 ENSP00000406345 ENSP00000323077

ENSP00000408690

Reactome Protein details: Q9P218
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for COL20A1
	GenScript Custom Purified and Recombinant Proteins Services for COL20A1
	Novus Biologicals COL20A1 Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005581	collagen	IEA	--
GO:0005615	extracellular space	IEA	--
GO:0005788	endoplasmic reticulum lumen	TAS	--
GO:0031012	colocalizes with extracellular matrix	TAS	--

COL20A1 for ontologies About GeneDecksing

COL20A1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for COL20A1
	GenScript Custom Superior Antibodies Services for COL20A1
	Novus Biologicals COL20A1 Antibodies
	Search for Antibodies for COL20A1 at Abcam
	Browse Antibodies at Uscn
	Search ThermoFisher Antibodies for COL20A1

Assay Products for COL20A1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for COL20A1
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

COL20A1 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR003961 Fibronectin_type3

IPR001791 Laminin_G

IPR013783 Ig-like_fold

IPR008160 Collagen

IPR008985 ConA-like_lec_gl_sf

Graphical View of Domain Structure for InterPro Entry Q9P218

ProtoNet protein and cluster: Q9P218

4 Blocks protein families:

IPB002035 Von Willebrand factor type A domain signature

IPB003129 Thrombospondin

IPB008160 Collagen triple helix repeat

IPB008161 Collagen helix repeat

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218

Similarity: Contains 2 collagen-like domains

Similarity: Contains 6 fibronectin type-III domains

Similarity: Contains 1 laminin G-like domain

Similarity: Contains 1 VWFA domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218

Function: Probable collagen protein

miRNA Products:		OriGene 3'-UTR Clone: COL20A1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL20A1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate COL20A1
		SwitchGear 3'UTR luciferase reporter plasmid: COL20A1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL20A1 OriGene shRNA RFP: COL20A1 OriGene siRNA: COL20A1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL20A1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for COL20A1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: COL20A1 (NM_020882)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL20A1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL20A1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for COL20A1
		Search LifeMap BioReagents cell lines for COL20A1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL20A1

1 GenomeRNAi human phenotype for COL20A1:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Collagen formation

	Collagen formation	1.00			Extracellular matrix organization	0.54
	Collagen biosynthesis and modifying enzymes	0.74			Secretion of collagens	0.49

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for COL20A1

	Extracellular matrix organization
	Secretion of collagens
	Collagen biosynthesis and modifying enzymes
	Collagen formation

COL20A1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for COL20A1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/42 Interacting proteins for COL20A1 (Q9P218³ ENSP00000351767⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 42)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TEX11	Q8IYF3³, ENSP00000340995⁴	I2D: score=4 STRING: ENSP00000340995
PDZD3	Q86UT5³	I2D: score=1
COL12A1	ENSP00000325146⁴	STRING: ENSP00000325146
COL13A1	ENSP00000348695⁴	STRING: ENSP00000348695
COL14A1	ENSP00000297848⁴	STRING: ENSP00000297848

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030198	extracellular matrix organization	TAS	--

COL20A1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

COL20A1 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for COL20A1
4 Novoseek chemical compound relationships for COL20A1 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
hydroxylysine	79.3	2	12444623 (1), 8268829 (1)
hydroxyproline	46.7	2	15528200 (1), 8268829 (1)
gold	1.82	1	2178159 (1)
tyrosine	0	1	9786938 (1)

Search CenterWatch for drugs/clinical trials and news about COL20A1 / COKA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for COL20A1 gene:

NM_020882.2

Unigene Cluster for COL20A1:

Collagen, type XX, alpha 1

Hs.271285 [show with all ESTs]

Unigene Representative Sequence: AB040943

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000358894(uc011aau.2) ENST00000479501 ENST00000422202(uc011aav.2)

ENST00000415763 ENST00000455906 ENST00000472502 ENST00000471582 ENST00000494913

ENST00000496810 ENST00000326996 ENST00000435874

miRNA Products:		OriGene 3'-UTR Clone: COL20A1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COL20A1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate COL20A1
		SwitchGear 3'UTR luciferase reporter plasmid: COL20A1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL20A1 OriGene shRNA RFP: COL20A1 OriGene siRNA: COL20A1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL20A1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: COL20A1 (NM_020882)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for COL20A1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL20A1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL20A1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat COL20A1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL20A1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL20A1

Additional cDNA sequence:

AB040943.1 AK098702.1 AL390141.1 BC013658.1 BC019637.1 BC041767.1 BC043183.1

6 DOTS entries:

DT.91651030 DT.100751911 DT.100751913 DT.100001519 DT.95216368 DT.100751912

24/42 AceView cDNA sequences (see all 42):

BC041767 AK098702 AB040943 BF528839 BC013658 BM704820 BG818387 BM548112

BC043183 BG820122 F04648 BC019637 Z45774 BF346541 BF345918 NM_020882

BG819225 BU730454 AL390141 BF347240 BF527501 BF531027 AW592591 BG820155

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for COL20A1 (see all 12) About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15a	·	15b	^	16	^	17	^	18	^	19a	·	19b	^	20a	·	20b	^	21	^
SP1:																																									-						-
SP2:
SP3:
SP4:																																									-
SP5:

ExUns:	22	^	23	^	24a	·	24b	^	25	^	26	^	27a	·	27b	^	28a	·	28b
SP1:					-								-
SP2:					-								-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for COL20A1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

COL20A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCATCTTGG

About this image

COL20A1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Type1 Off Cone Bipolar Cells

Bipolar, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See COL20A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for COL20A1

SOURCE GeneReport for Unigene cluster: Hs.271285

UniProtKB/Swiss-Prot: COKA1_HUMAN, Q9P218

Tissue specificity: High expression in heart, lung, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary,

subthalamic nucleus and fetal liver. Weak expression in other tissues tested

SABiosciences Custom PCR Arrays for COL20A1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL20A1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat COL20A1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL20A1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL20A1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL20A1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for COL20A1 gene from 3/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	COL20A1¹	collagen, type XX, alpha 1	62.61(n) 56(a)		419243 NM_001004392.1 NP_001004392.1
lizard (Anolis carolinensis)	Reptilia	COL20A1⁶	--	32(a)	1 ↔ 1	4(153548485-153680858)
African clawed frog (Xenopus laevis)	Amphibia	BI442495.1²	--	77.44(n)		BI442495.1

ENSEMBL Gene Tree for COL20A1 (if available)
TreeFam Gene Tree for COL20A1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for COL20A1 gene

VWA1² MATN4² COL14A1² COL9A1² MATN3² MATN2² COL12A1² VIT²

COL9A3² COCH² COL9A2² VWA2² MATN1² COL21A1²

6 SIMAP similar genes for COL20A1 using alignment to 3 protein entries: COKA1_HUMAN (see all proteins):

COL12A1 COL7A1 XB DKFZp434L081 FCN2 ITGA2

COL20A1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs141973943^1,2		--	61922651(+)	`GACCCG/TGACGC`	1	--	us2k¹		0	--	--	--	--
rs200248173^1,2		--	61922733(+)	`CGCCC-/GG TGCCTGGTGC`	1	--	us2k¹		0	--	--	--	--
rs144409261^1,2	C,	--	61922742(+)	`CTGGT-/GCGCCTG`	1	--	us2k¹		0	--	--	--	--
rs4809283^1,2	C,F,A,	--	61922918(+)	`GGGTGT/CGGTGG`	1	--	us2k¹		3		NA CSA	124
rs187227272^1,2		--	61922930(+)	`TCACAC/TCTGTA`	1	--	us2k¹		0	--	--	--	--
rs6090344^1,2	C,F,A,H,	--	61922957(+)	`AGGCCG/AAGGCG`	1	--	us2k¹		1		NA	6
rs4809284^1,2	C,F,H,	--	61923157(+)	`TTGTTC/TTCTAG`	1	--	us2k¹		15		NS EA NA CSA	1540
rs191738437^1,2		--	61923192(+)	`ATCTCA/GAGAAA`	1	--	us2k¹		0	--	--	--	--
rs138749145^1,2		--	61923355(+)	`GCCAGC/TGCTGG`	1	--	us2k¹		0	--	--	--	--
rs78432831^1,2	C	--	61923604(+)	`CAGTGC/GTCCTG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for COL20A1 (61924538 - 61966203 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for COL20A1
3 CNVs: 5148 30133 31044
1 Indel: 26894

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COL20A1

DNA2.0 Custom Variant and Variant Library Synthesis for COL20A1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

COL20A1 for disorders About GeneDecksing

5 diseases for COL20A1: About MalaCards

metabolic disorders kidney disease nephropathy atherosclerosis

obesity

Export disorders for COL20A1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for COL20A1 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with COL20A1)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)^{1, 2, 3} Nagase T.... Ohara O. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)¹ Rual J.F....Vidal M. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Design, expression and characterization of collagen-like proteins based on the cell adhesive and crosslinking sequences derived from native collagens. (PubMed id 15632304)⁹ Yao J....Asakura T. (2004)
Testing the utility of rationally engineered recombinant collagen-like proteins for applications in tissue engineering. (PubMed id 16278869)⁹ Ito H....Fertala A. (2006)
A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. (PubMed id 15647274)⁹ Humtsoe J.O....Wary K.K. (2005)
Prospects and limitations of the rational engineering of fibrillar collagens. (PubMed id 12931004)⁹ Majsterek I....Fertala A. (2003)
Evidence for increased hydroxylation of pyrrolidone amino acid residues in the cuticle of mature Onchocerca volvulus. (PubMed id 9197461)⁹ Sakwe A.M. and Titanji V.P. (1997)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57642	HGNC: 14670	AceView: KIAA1510	Ensembl:ENSG00000101203	euGenes: HUgn57642
ECgene: COL20A1	H-InvDB: COL20A1

(According to HUGE)
About This Section

HUGE: KIAA1510

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for COL20A1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for COL20A1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for COL20A1 gene:
Search GeneIP for patents involving COL20A1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for COL20A1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COL20A1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for COL20A1
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for COL20A1		OriGene 3'-UTR Clone for COL20A1
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COL20A1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for COL20A1		OriGene Custom Protein Services for COL20A1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat COL20A1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COL20A1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COL20A1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COL20A1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COL20A1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COL20A1

	GenScript Custom Purified and Recombinant Proteins Services for COL20A1		GenScript cDNA clones with any tag delivered in your preferred vector for COL20A1
	GenScript Custom Assay Services for COL20A1		GenScript Custom Superior Antibodies Services for COL20A1
	GenScript Custom overexpressing Cell Line Services for COL20A1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in COL20A1 promoter
	Search Chromatin IP Primers for COL20A1
	RT² qPCR Primer Assay in human, mouse, rat COL20A1
	Search GNC Networks for COL20A1
	SABiosciences Custom PCR Arrays for COL20A1

Search Tocris compounds for COL20A1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	COL20A1 antibodies
	COL20A1 proteins

	Search for Antibodies for COL20A1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for COL20A1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn

Search LifeMap BioReagents cell lines for COL20A1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL20A1

	SwitchGear 3'UTR luciferase reporter plasmids for COL20A1
	SwitchGear Promoter luciferase reporter plasmids for COL20A1

Search ThermoFisher Antibodies for COL20A1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COL20A1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes COL20A1 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

COL20A1 Gene

collagen, type XX, alpha 1

Aliases
for COL20A1 gene

Summaries
for COL20A1 gene

Genomic Views
for COL20A1 gene

Proteins
for COL20A1 gene

Protein Domains /
Families
for COL20A1 gene

Function
for COL20A1 gene

Pathways & Interactions
for COL20A1 gene

Drugs & Compounds
for COL20A1 gene

Transcripts
for COL20A1 gene

Expression
for COL20A1 gene

Orthologs
for COL20A1 gene

Paralogs
for COL20A1 gene

Genomic Variants
for COL20A1 gene

Disorders / Diseases
for COL20A1 gene

Publications
for COL20A1 gene

External Searches for COL20A1 gene

Genome Databases showing COL20A1 gene

Other Databases showing COL20A1 gene

Specialized Databases showing COL20A1 gene

Intellectual Property
for COL20A1 gene

Products
for COL20A1 gene

View Random Gene

Advanced Search

Export list of displayed genes

COL20A1 Gene

collagen, type XX, alpha 1

Aliasesfor COL20A1 gene

Summariesfor COL20A1 gene

Genomic Viewsfor COL20A1 gene

Proteinsfor COL20A1 gene

Protein Domains /Familiesfor COL20A1 gene

Functionfor COL20A1 gene

Pathways & Interactionsfor COL20A1 gene

Drugs & Compoundsfor COL20A1 gene

Transcriptsfor COL20A1 gene

Expression for COL20A1 gene

Orthologsfor COL20A1 gene

Paralogsfor COL20A1 gene

Genomic Variantsfor COL20A1 gene

Disorders / Diseasesfor COL20A1 gene

Publicationsfor COL20A1 gene

External Searches for COL20A1 gene

Genome Databases showing COL20A1 gene

Other Databases showing COL20A1 gene

Specialized Databases showing COL20A1 gene

Intellectual Propertyfor COL20A1 gene

Productsfor COL20A1 gene

View Random Gene

Aliases
for COL20A1 gene

Summaries
for COL20A1 gene

Genomic Views
for COL20A1 gene

Proteins
for COL20A1 gene

Protein Domains /
Families
for COL20A1 gene

Function
for COL20A1 gene

Pathways & Interactions
for COL20A1 gene

Drugs & Compounds
for COL20A1 gene

Transcripts
for COL20A1 gene

Expression
for COL20A1 gene

Orthologs
for COL20A1 gene

Paralogs
for COL20A1 gene

Genomic Variants
for COL20A1 gene

Disorders / Diseases
for COL20A1 gene

Publications
for COL20A1 gene

Intellectual Property
for COL20A1 gene

Products
for COL20A1 gene