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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COL19A1 Gene

protein-coding   GIFtS: 53
GCID: GC06P070633

Collagen, Type XIX, Alpha 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Collagen, Type XIX, Alpha 11 2     A1 Chain Of Type XIX Collagen2
Collagen Alpha-1(Y) Chain2 3     Collagen Alpha 1 (Y) Chain2
COL9A1L2 5     Collagen Alpha-1(XIX) Chain2
D6S228E2 5     Collagen XIX, Alpha-1 Polypeptide2

External Ids:    HGNC: 21961   Entrez Gene: 13102   Ensembl: ENSG000000822937   OMIM: 1201655   UniProtKB: Q149933   
ORGUL members:         
NONCODE14:n342894      

Export aliases for COL19A1 gene to outside databases

Previous GC identifers: GC06P070534 GC06P070572 GC06P067767


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COL19A1 Gene:
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated
collagens with interrupted helices). Although the function of this collagen is not known, other members of this
collagen family are found in association with fibril-forming collagens such as type I and II, and serve to
maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large
3' UTR which has not been completely sequenced. (provided by RefSeq, Jul 2008)

GeneCards Summary for COL19A1 Gene: 
COL19A1 (collagen, type XIX, alpha 1) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with COL19A1 include neuronitis, and among its related super-pathways are Collagen biosynthesis and modifying enzymes and FAK1 Signaling. GO annotations related to this gene include extracellular matrix structural constituent and protein binding, bridging. An important paralog of this gene is COL25A1.

UniProtKB/Swiss-Prot: COJA1_HUMAN, Q14993
Function: May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal
myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the
sphinteric smooth muscle

Gene Wiki entry for COL19A1 (Collagen, type XIX, alpha 1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007299.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COL19A1 gene promoter:
         Spz1   Pbx1a   Brachyury   HTF   C/EBPalpha   FOXL1   Nkx6-1   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOL19A1 promoter sequence
   Search SABiosciences Chromatin IP Primers for COL19A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COL19A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q12-q13   Ensembl cytogenetic band:  6q13   HGNC cytogenetic band: 6q12-q13

COL19A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COL19A1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P070633:  view genomic region     (about GC identifiers)

Start:
70,576,448 bp from pter      End:
70,922,157 bp from pter
Size:
345,710 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COJA1_HUMAN, Q14993 (See protein sequence)
Recommended Name: Collagen alpha-1(XIX) chain precursor  
Size: 1142 amino acids; 115221 Da
Subunit: Oligomer; disulfide-linked
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Sequence caution: Sequence=CAC12699.3; Type=Erroneous gene model prediction; Sequence=CAI42319.2; Type=Erroneous
gene model prediction; Sequence=CAI42496.2; Type=Erroneous gene model prediction;
Secondary accessions: Q00559 Q05850 Q12885 Q13676 Q14DH1 Q5JUF0 Q5T424 Q9H572 Q9NPZ2 Q9NQP2

Explore the universe of human proteins at neXtProt for COL19A1: NX_Q14993

Explore proteomics data for COL19A1 at MOPED 

Post-translational modifications:

  • UniProtKB: Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the
    chains
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14993

  • COL19A1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COL19A1 Protein Expression
    REFSEQ proteins: NP_001849.2  
    ENSEMBL proteins: 
     ENSP00000316030   ENSP00000377013   ENSP00000416556  
    Reactome Protein details: Q14993
    Human Recombinant Protein Products for COL19A1: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005578proteinaceous extracellular matrix NAS1639419
    GO:0005581collagen NAS7775380
    GO:0005788endoplasmic reticulum lumen TAS--

    COL19A1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    COLLAGEN: Collagens

    4 InterPro protein domains:
     IPR013320 ConA-like_subgrp
     IPR001791 Laminin_G
     IPR008160 Collagen
     IPR008985 ConA-like_lec_gl_sf

    Graphical View of Domain Structure for InterPro Entry Q14993

    ProtoNet protein and cluster: Q14993

    3 Blocks protein domains:
    IPB003129 Thrombospondin
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: COJA1_HUMAN, Q14993
    Domain: The numerous interruptions in the triple helix may make this molecule either elastic or flexible
    Similarity: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family
    Similarity: Contains 11 collagen-like domains
    Similarity: Contains 1 laminin G-like domain


    COL19A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COJA1_HUMAN, Q14993
    Function: May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal
    myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the
    sphinteric smooth muscle

         Genatlas biochemistry entry for COL19A1:
    collagen,type XIX,alpha 1,fibril associated collagen with interrupted triple helices (FACIT),expressed in
    cartilage

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent NAS1639419
    GO:0030674protein binding, bridging NAS1639419
         
    COL19A1 for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Col19a1):
     behavior/neurological  digestive/alimentary  growth/size  integument  mortality/aging 
     muscle 

    COL19A1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for COL19A1: Col19a1tm2Rmz Col19a1tm1Rmz

       inGenious Targeting Laboratory - Custom generated mouse model solutions for COL19A1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for COL19A1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Collagen biosynthesis and modifying enzymes
    Collagen biosynthesis and modifying enzymes0.74
    Extracellular matrix organization0.39
    Collagen formation0.74
    Blood Coagulation Cascade0.39
    Intrinsic Prothrombin Activation Pathway0.40
    2Integrin Pathway
    Integrin Pathway0.67
    UPA-UPAR Pathway0.56
    FAK1 Signaling0.67
    Inhibition of Angiogenesis by TSP10.50
    GnRH Signaling0.56
    Transendothelial Migration of Leukocytes0.38
    3Rho Family GTPases
    Rho Family GTPases0.61
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    ILK Signaling0.49
    MAPK Signaling0.58
    4Degradation of the extracellular matrix
    Degradation of the extracellular matrix0.79
    Degradation of collagen0.79
    5PTEN Pathway
    PTEN Pathway0.56
    Phospholipase-C Pathway0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/15 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for COL19A1 (see all 15)
        MAPK Signaling
    Molecular Mechanisms of Cancer
    PTEN Pathway
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway

    5        Reactome Pathways for COL19A1
        Extracellular matrix organization
    Collagen biosynthesis and modifying enzymes
    Degradation of the extracellular matrix
    Collagen formation
    Degradation of collagen



    COL19A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COL19A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/40 Interacting proteins for COL19A1 (ENSP000003160304) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COL11A1ENSP000003511634STRING: ENSP00000351163
    COL12A1ENSP000003251464STRING: ENSP00000325146
    COL13A1ENSP000003486954STRING: ENSP00000348695
    COL14A1ENSP000002978484STRING: ENSP00000297848
    COL15A1ENSP000003641404STRING: ENSP00000364140
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development TAS9143499
    GO:0007155cell adhesion NAS7775380
    GO:0007519skeletal muscle tissue development IEA--
    GO:0016337cell-cell adhesion NAS1639419
    GO:0022617extracellular matrix disassembly TAS--

    COL19A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COL19A1 (COJA1)

    Search CenterWatch for drugs/clinical trials and news about COL19A1 / COJA1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COL19A1 gene: 
    NM_001858.4  

    Unigene Cluster for COL19A1:

    Collagen, type XIX, alpha 1
    Hs.444842  [show with all ESTs]
    Unigene Representative Sequence: NM_001858
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322773(uc003pfc.1 uc010kam.2) ENST00000478620 ENST00000476656
    ENST00000483745 ENST00000393344 ENST00000455415
    miRNA
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    8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate COL19A1 (see all 79):
    hsa-miR-194* hsa-miR-106a hsa-miR-199a-3p hsa-miR-3138 hsa-miR-3074-3p hsa-miR-519a hsa-miR-502-3p hsa-miR-93
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    Additional mRNA sequence: 

    AK309023.1 AK310621.1 BC070177.1 BC113362.1 BC113364.1 D38163.1 M63597.1 U09279.1 

    2 DOTS entries:

    DT.209387  DT.95286205 

    16 AceView cDNA sequences:

    BC070177 CA396452 NM_001858 M63597 AW614561 U09279 BG399866 AL705169 
    AA904409 L12347 D38163 BF434455 CD694117 AW139403 CF144008 BG217174 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COL19A1 expression in normal human tissues (normalized intensities)      COL19A1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    COL19A1 Expression
    About this image


    COL19A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 7 entries
             Endochondral Facial Bones
             skeleton/cranium/chondrocranium   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             skeleton/cranium/chondrocranium   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             skeleton/cranium/chondrocranium   
     
     Gut Tube (Gastrointestinal Tract)
             Primitive gut tube-like cells ( A scalable, suspension protocol for derivation of...
     
     Eye (Sensory Organs)
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer

    See COL19A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COL19A1

    SOURCE GeneReport for Unigene cluster: Hs.444842

    UniProtKB/Swiss-Prot: COJA1_HUMAN, Q14993
    Tissue specificity: Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in
    umbilical cord

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COL19A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for COL19A1 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Col19a11 , 5 collagen, type XIX, alpha 11, 5 85.9(n)1
    83.61(a)1
      1 (9.99 cM)5
    128231  NM_007733.21  NP_031759.21 
     242618905 
    chicken
    (Gallus gallus)
    Aves LOC1008581471 collagen alpha-1(IV) chain-like 73.48(n)
    74.9(a)
      100858147  XM_003640999.1  XP_003641047.1 
    lizard
    (Anolis carolinensis)
    Reptilia COL19A16
    Uncharacterized protein
    63(a)
    1 ↔ 1
    1(167240397-167410048)


    ENSEMBL Gene Tree for COL19A1 (if available)
    TreeFam Gene Tree for COL19A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for COL19A1 gene
    COL25A12  COL9A12  COL22A12  COL13A12  COL9A32  COL9A22  COL16A12  COL21A12  
    COL23A12  

    COL19A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6608 SNPs in COL19A1 are shown (see all 6608)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0357464
    A breast cancer sample4--see VAR_0357462 G D mis40--------
    VAR_0357474
    A breast cancer sample4--see VAR_0357472 K N mis40--------
    rs1477262231,2
    --70574767(+) CAATAC/TTAGAA 1 -- us2k10--------
    rs1907456981,2
    --70574831(+) TCAAAG/TATCTT 1 -- us2k10--------
    rs1492167551,2
    --70574834(+) AATATC/GTTAAC 1 -- us2k10--------
    rs1434132781,2
    C--70574853(+) AATTAC/TTAAAA 1 -- us2k10--------
    rs1483781791,2
    --70574871(+) GAAAAC/TAATTC 1 -- us2k10--------
    rs24874311,2
    C,F,A--70574925(+) CAAAAC/TTGTGG 1 -- us2k111Minor allele frequency- T:0.25NA WA CSA EA 373
    rs1823648451,2
    --70575060(+) GCAAGG/TTATAT 1 -- us2k10--------
    rs1861806741,2
    --70575193(+) AGCGTA/GACTCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for COL19A1 (70576448 - 70826448 bp, first 250kb of COL19A1)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for COL19A1 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2658033CNV Deletion23128226
    esv2663730CNV Deletion23128226
    esv2732254CNV Deletion23290073
    nsv507337CNV Insertion20534489
    nsv511895CNV Loss21212237
    nsv886141CNV Loss21882294
    nsv819361CNV Loss19587683
    nsv830682CNV Loss17160897
    nsv463151CNV Loss19166990
    nsv525985CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 120165    OMIM disorders: --

    2 diseases for COL19A1:    About MalaCards
    neuronitis    


    COL19A1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): COL19A1
    Human Genome Epidemiology (HuGE) Navigator: COL19A1 (1 document)

    Export disorders for COL19A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COL19A1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with COL19A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human cDNA clones transcribed from an unusually high-molecular-weight RNA encode a new collagen chain. (PubMed id 7916703)1, 2, 3 Myers J.C....Dion A.S. (1993)
    2. Structure of the human type XIX collagen (COL19A1) gene, which suggests it has arisen from an ancestor gene of the FACIT family. (PubMed id 9344653)1, 2, 9 Khaleduzzaman M....Yoshioka H. (1997)
    3. Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13. (PubMed id 9143499)1, 3, 9 Gerecke D.R.... Burgeson R.E. (1997)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Type XIX collagen purified from human umbilical cord is characterized by multiple sharp kinks delineating collagenous subdomains and by intermolecular aggregates via globular, disulfide-linked, and heparin- binding amino termini. (PubMed id 12788917)1, 2 Myers J.C.... Weisel J.W. (2003)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    8. The mRNA for alpha 1(XIX) collagen chain, a new member of FACITs, contains a long unusual 3' untranslated region and displays many unique splicing variants. (PubMed id 7775380)1, 2 Inoguchi K.... Ninomiya Y. (1995)
    9. The triple-helical region of human type XIX collagen consists of multiple collagenous subdomains and exhibits limited sequence homology to alpha 1(XVI). (PubMed id 8034603)1, 2 Myers J.C....Dion A.S. (1994)
    10. Synteny between the loci for a novel FACIT-like collagen locus (D6S228E) and alpha 1 (IX) collagen (COL9A1) on 6q12-q14 in humans. (PubMed id 1639419)1, 2 Yoshioka H.... Gordon M.K. (1992)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1310 HGNC: 2196 AceView: COL19A1 Ensembl:ENSG00000082293 euGenes: HUgn1310
    ECgene: COL19A1 H-InvDB: COL19A1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COL19A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COL19A1 gene:
    Search GeneIP for patents involving COL19A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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