Aliases for COL18A1 Gene
Aliases for COL18A1 Gene
External Ids for COL18A1 Gene
- HGNC: 2195
- Entrez Gene: 80781
- Ensembl: ENSG00000182871
- OMIM: 120328
- UniProtKB: P39060
Previous HGNC Symbols for COL18A1 Gene
- KNO
Previous GeneCards Identifiers for COL18A1 Gene
- GC21P043334
- GC21P045681
- GC21P045649
- GC21P046825
- GC21P032201
Summaries for COL18A1 Gene
-
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
GeneCards Summary for COL18A1 Gene
COL18A1 (Collagen Type XVIII Alpha 1) is a Protein Coding gene. Diseases associated with COL18A1 include Knobloch Syndrome, Type 1 and Knobloch Syndrome. Among its related pathways are ERK Signaling and Phospholipase-C Pathway. GO annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is COL15A1.
UniProtKB/Swiss-Prot for COL18A1 Gene
-
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
-
Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COL18A1 Gene
Genomics for COL18A1 Gene
Regulatory Elements for COL18A1 Gene
Enhancers for COL18A1 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around COL18A1 on UCSC Golden Path with GeneCards custom track
Promoters for COL18A1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around COL18A1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the COL18A1 gene promoter:
Regulatory Element Products
Genomic Location for COL18A1 Gene
- Chromosome:
- 21
- Start:
- 45,405,137 bp from pter
- End:
- 45,513,720 bp from pter
- Size:
- 108,584 bases
- Orientation:
- Plus strand
Genomic View for COL18A1 Gene
Genes around COL18A1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 21q22.3 by Ensembl
- 21q22.3 by Entrez Gene
- 21q22.3 by HGNC
COL18A1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for COL18A1 Gene
Proteins for COL18A1 Gene
-
Protein details for COL18A1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P39060-COIA1_HUMAN
- Recommended name:
- Collagen alpha-1(XVIII) chain
- Protein Accession:
- P39060
- A8MVI4
- Q58EX6
- Q6RZ39
- Q6RZ40
- Q6RZ41
- Q8N4S4
- Q8WXI5
- Q96T70
- Q9UK38
- Q9Y6Q7
- Q9Y6Q8
Protein attributes for COL18A1 Gene
- Size:
- 1754 amino acids
- Molecular mass:
- 178188 Da
- Quaternary structure:
- No Data Available
Three dimensional structures from OCA and Proteopedia for COL18A1 Gene
Protein Expression for COL18A1 Gene
Post-translational modifications for COL18A1 Gene
- Prolines at the third position of the tripeptide repeating unit (G-X-Y) of the triple-helical regions are hydroxylated.
- Glycosylation at Asn 68, Asn 129, Asn 164, Asn 691, Thr 1292, Ser 1304, and Thr 1332
- Modification sites at PhosphoSitePlus
Other Protein References for COL18A1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for COL18A1
- R&D Systems Antibodies for COL18A1 (Endostatin)
- Novus Biologicals Antibodies for COL18A1
- Abcam antibodies for Endostatin
-
Cloud-Clone Corp. Antibodies for COL18A1
- Invitrogen Antibodies for COL18A1
- antibodies-online Antibodies for COL18A1: See all 134
- GeneTex COL18A1 antibody for COL18A1
-
Santa Cruz Biotechnology (SCBT) Antibodies for COL18A1
Protein Products
- EMD Millipore Purified and/or Recombinant COL18A1 Protein
- R&D Systems Proteins and Enzymes for COL18A1 (Endostatin)
-
OriGene Purified Proteins for COL18A1
- Search Origene for MassSpec and Protein Over-expression Lysates for COL18A1
- Origene Custom Protein Services for COL18A1
- Novus Biologicals proteins for COL18A1
- ProSpec Recombinant Proteins for COL18A1
-
Cloud-Clone Corp. Proteins for COL18A1
- antibodies-online Proteins for COL18A1: See all 32
- Search antibodies-online for peptides
- GeneTex Endostatin recombinant protein (GTX53825) for COL18A1
- Abcam proteins for Endostatin
Assay Products
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for COL18A1 (Endostatin)
- antibodies-online Kits for COL18A1: See all 73
- Abcam assays for Endostatin
No data available for DME Specific Peptides for COL18A1 Gene
Domains & Families for COL18A1 Gene
Gene Families for COL18A1 Gene
- HGNC:
Protein Domains for COL18A1 Gene
Suggested Antigen Peptide Sequences for COL18A1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P39060UniProtKB/Swiss-Prot:
COIA1_HUMAN :- Contains 1 FZ (frizzled) domain.
- Belongs to the multiplexin collagen family.
- Domain:
-
- Contains 1 FZ (frizzled) domain.
- Contains 1 laminin G-like domain.
- Family:
-
- Belongs to the multiplexin collagen family.
Function for COL18A1 Gene
Molecular function for COL18A1 Gene
- GENATLAS Biochemistry:
- collagen,type XVIII,alpha 1,multiplexin family with interrupted helical domain
- UniProtKB/Swiss-Prot Function:
- COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
- UniProtKB/Swiss-Prot Function:
- Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
Phenotypes for COL18A1 Gene
- MGI mutant phenotypes for COL18A1:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for COL18A1:
Animal Model Products
-
Taconic Biosciences Mouse Models for COL18A1
-
ViGene Biosciences lentiviral particle packaged cDNA for COL18A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
- Search ViGene Biosciences for COL18A1
CRISPR Products
-
OriGene CRISPR knockouts for COL18A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL18A1
- GenScript: Design CRISPR guide RNA sequences for COL18A1
miRNA for COL18A1 Gene
- miRTarBase miRNAs that target COL18A1
-
- hsa-mir-877-3p (MIRT037044)
- hsa-mir-92a-3p (MIRT049203)
- hsa-mir-6749-5p (MIRT527331)
- hsa-mir-450a-1-3p (MIRT527332)
- hsa-mir-3977 (MIRT527333)
- hsa-mir-3157-5p (MIRT527334)
- hsa-mir-8059 (MIRT527335)
- hsa-mir-4471 (MIRT527336)
- hsa-mir-1292-5p (MIRT527337)
- hsa-mir-661 (MIRT527338)
- hsa-mir-27b-5p (MIRT527339)
- hsa-mir-7155-5p (MIRT527340)
- hsa-mir-6852-5p (MIRT527341)
- hsa-mir-4538 (MIRT527342)
- hsa-mir-4453 (MIRT527343)
miRNA Products
- Search ViGene Biosciences for COL18A1
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for COL18A1
- Browse OriGene Inhibitory RNA Products For COL18A1
-
ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
Clone Products
- OriGene clones in human for COL18A1
- OriGene ORF clones in human,mouse,rat for COL18A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for COL18A1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for COL18A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for COL18A1 Gene
Localization for COL18A1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for COL18A1 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| extracellular | 5 |
| plasma membrane | 3 |
| golgi apparatus | 2 |
| vacuole | 2 |
| cytoskeleton | 1 |
| cytosol | 1 |
| lysosome | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005604 | basement membrane | IEA | -- |
Pathways & Interactions for COL18A1 Gene
More details on SuperPathways for COL18A1| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Integrin Pathway |
.67
.67
.56
|
.56
|
| 2 | Collagen biosynthesis and modifying enzymes | ||
| 3 | ERK Signaling |
.61
.58
|
.49
|
| 4 | Degradation of the extracellular matrix | ||
| 5 | Phospholipase-C Pathway |
.56
|
Pathways by source for COL18A1 Gene
2 BioSystems pathways for COL18A1 Gene
1 KEGG pathway for COL18A1 Gene
15 Qiagen pathways for COL18A1 Gene
Interacting Proteins for COL18A1 Gene
Selected Interacting proteins:
ENSP00000347665
P39060-COIA1_HUMAN
for COL18A1 Gene via
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007601 | visual perception | TAS | 10942434 |
| GO:0009887 | organ morphogenesis | TAS | 10942434 |
| GO:0022617 | extracellular matrix disassembly | TAS | -- |
| GO:0030335 | positive regulation of cell migration | IEA | -- |
Transcripts for COL18A1 Gene
mRNA/cDNA for COL18A1 Gene
- (3) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (195) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for COL18A1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for COL18A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL18A1
- GenScript: Design CRISPR guide RNA sequences for COL18A1
miRNA Products
- Search ViGene Biosciences for COL18A1
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for COL18A1
- Browse OriGene Inhibitory RNA Products For COL18A1
-
ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
Clone Products
- OriGene clones in human for COL18A1
- OriGene ORF clones in human,mouse,rat for COL18A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for COL18A1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
- Metanephros
-
Hair (Integumentary System)
- Bulge Stem Cells Bulge
- Basal Keratinocytes Embryonic Epidermis
-
Eye (Sensory Organs)
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
- Optic Nerve
-
Epithelial Cells
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
- Basal Keratinocytes Embryonic Epidermis
- Umbilical Cord (Extraembryonic Tissues)
-
Heart (Cardiovascular System)
- Primitive Heart Tube Cells Primitive Heart Tube
-
Testis (Reproductive System)
- Sertoli cells Seminiferous Tubules
-
Gonad (Reproductive System)
- Primordial Germ Cells Primitive Gonad
-
Epidermis (Integumentary System)
- Basal Keratinocytes Embryonic Epidermis
- Lower Urinary Tract (Urinary System)
- Thymus (Hematopoietic System)
- Mesenchymal Stem Cells (Uncategorized)
mRNA differential expression in normal tissues according to GTEx for COL18A1 Gene
This gene is overexpressed in Artery - Tibial (x5.0), Artery - Coronary (x4.6), and Liver (x4.5).
This gene is overexpressed in Amniocyte (13.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for COL18A1 Gene
SOURCE GeneReport for Unigene cluster for COL18A1 Gene Hs.517356
mRNA Expression by UniProt/SwissProt for COL18A1 Gene
P39060-COIA1_HUMAN
Tissue specificity:
Present in multiple organs with highest levels in liver, lung and kidney.
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for COL18A1
Orthologs for COL18A1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| mouse (Mus musculus) |
Mammalia | Col18a1 35 |
|
||
| Col18a1 16 |
|
||||
| Col18a1 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | COL18A1 35 |
|
||
| COL18A1 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Col18a1 35 |
|
||
| cow (Bos Taurus) |
Mammalia | COL18A1 36 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | COL18A1 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | COL18A1 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | COL18A1 35 |
|
||
| COL18A1 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | COL18A1 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | col18a1 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | -- 35 |
|
||
| col18a1 36 |
|
OneToMany | |||
| COL18A1 (2 of 2) 36 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | mp 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | cle-1 37 |
|
|
|
| cle-1 36 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for COL18A1:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for COL18A1 Gene
(1) SIMAP similar genes for COL18A1 Gene using alignment to 6 proteins:
Variants for COL18A1 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for COL18A1 Gene
- COIA1_HUMAN-P39060
- There is an association between a polymorphism in position 1675 and prostate cancer. Heterozygous Asn-1675 individuals have a 2.5 times increased chance of developing prostate cancer as compared with homozygous Asp-1675 individuals.
| SNP ID | Clin | Chr 21 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_012709 | - | ||||
| rs61735029 | - | 45,455,676(+) | GCCCC(A/T)GGGGC | intron-variant, reference, missense | |
| rs114139997 | - | 45,455,861(+) | GTGTC(A/G)GAGCC | intron-variant, reference, missense | |
| rs62000962 | - | 45,490,296(+) | ATGGA(A/G)TCCCC | reference, missense | |
| rs79980197 | - | 45,491,274(+) | CCCCC(C/G/T)CGGAC | reference, missense |
Residual Variation Intolerance Score:
90.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
15.32;
97.06% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for COL18A1 Gene
- Human Gene Mutation Database (HGMD)
- COL18A1
Disorders for COL18A1 Gene
(14) MalaCards diseases for COL18A1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| knobloch syndrome, type 1 |
|
|
| knobloch syndrome |
|
|
| occipital encephalocele |
|
|
| encephalocele |
|
|
| alveolar capillary dysplasia with misalignment of pulmonary veins |
|
|
Search COL18A1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
COIA1_HUMAN- Knobloch syndrome 1 (KNO1) [MIM:267750]: A developmental disorder primarily characterized by typical eye abnormalities, including high myopia, cataracts, dislocated lens, vitreoretinal degeneration, and retinal detachment, with occipital skull defects, which can range from occipital encephalocele to occult cutis aplasia. {ECO:0000269 PubMed:10942434, ECO:0000269 PubMed:23667181}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for COL18A1
No data available for Genatlas for COL18A1 Gene
Publications for COL18A1 Gene
- Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure. (PMID: 10942434) Sertie A.L. … Passos-Bueno M.R. (Hum. Mol. Genet. 2000) 2 3 4 23 67
- CNS malformations in Knobloch syndrome with splice mutation in COL18A1 gene. (PMID: 17546652) Keren B. … Verloes A. (Am. J. Med. Genet. A 2007) 2 3 23
- Cloning of cDNA and genomic DNA encoding human type XVIII collagen and localization of the alpha 1(XVIII) collagen gene to mouse chromosome 10 and human chromosome 21. (PMID: 8188291) Oh S.P. … Olsen B.R. (Genomics 1994) 2 3 23
- Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome. (PMID: 19390655) Suzuki O. … Passos-Bueno M.R. (Mol. Vis. 2009) 3 23
- A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS). (PMID: 19961619) Castro-Giner F. … de Cid R. (BMC Med. Genet. 2009) 3 23
Products for COL18A1 Gene
- Browse Small Molecules at EMD Millipore
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for COL18A1
- EMD Millipore Purified and/or Recombinant COL18A1 Protein
- Browse Kits and Assays available from EMD Millipore
- EMD Millipore genomic analysis products
- R&D Systems Antibodies for COL18A1 (Endostatin)
- R&D Systems Proteins and Enzymes for COL18A1 (Endostatin)
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for COL18A1 (Endostatin)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Custom Assay Services
- OriGene Purified Proteins for COL18A1
- Search Origene for MassSpec and Protein Over-expression Lysates for COL18A1
- Origene Custom Protein Services for COL18A1
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for COL18A1
- Browse OriGene Inhibitory RNA Products For COL18A1
- OriGene qPCR primer pairs for COL18A1
- OriGene CRISPR knockouts for COL18A1
- OriGene clones in human for COL18A1
- OriGene ORF clones in human,mouse,rat for COL18A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Purified and Recombinant Proteins for COL18A1
- GenScript Custom Purified and Recombinant Proteins Services for COL18A1
- GenScript Custom Assay Services for COL18A1
- GenScript Custom overexpressing Cell Line Services for COL18A1
- GenScript: Design CRISPR guide RNA sequences for COL18A1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for COL18A1
- Novus Biologicals Antibodies for COL18A1
- Novus Biologicals proteins for COL18A1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for Endostatin
- Abcam proteins for Endostatin
- Abcam assays for Endostatin
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ProSpec Recombinant Proteins for COL18A1
- Cloud-Clone Corp. Antibodies for COL18A1
- Cloud-Clone Corp. Proteins for COL18A1
- Browse Assay Kits at Cloud-Clone Corp.
- Taconic Biosciences Mouse Models for COL18A1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for COL18A1: See all 134
- antibodies-online Kits for COL18A1: See all 73
- antibodies-online Proteins for COL18A1: See all 32
- Search antibodies-online for peptides
- GeneTex COL18A1 antibody for COL18A1
- GeneTex Endostatin recombinant protein (GTX53825) for COL18A1
- ViGene Biosciences adenoviral particle packaged cDNA for COL18A1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for COL18A1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for COL18A1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for COL18A1 gene
- Search ViGene Biosciences for COL18A1
- Search ViGene Biosciences for COL18A1
- Santa Cruz Biotechnology (SCBT) Antibodies for COL18A1
- Search Santa Cruz Biotechnology (SCBT) for COL18A1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for COL18A1
Sources for COL18A1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon