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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COG7 Gene

protein-coding   GIFtS: 53
GCID: GC16M023307

Component Of Oligomeric Golgi Complex 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Component Of Oligomeric Golgi Complex 71 2 3
COG Complex Subunit 72 3
CDG2E2 5
Conserved Oligomeric Golgi Complex Subunit 72

External Ids:    HGNC: 186221   Entrez Gene: 919492   Ensembl: ENSG000001684347   OMIM: 6069785   UniProtKB: P834363   

Export aliases for COG7 gene to outside databases

Previous GC identifers: GC16M022808 GC16M023487 GC16M023327 GC16M023366 GC16M021487


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for COG7 Gene:
The protein encoded by this gene resides in the golgi, and constitutes one of the 8 subunits of the conserved
oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localization. Mutations in this
gene are associated with the congenital disorder of glycosylation type IIe.(provided by RefSeq, May 2010)

GeneCards Summary for COG7 Gene: 
COG7 (component of oligomeric golgi complex 7) is a protein-coding gene. Diseases associated with COG7 include congenital disorder of glycosylation type 2e, and congenital disorder of glycosylation. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: COG7_HUMAN, P83436
Function: Required for normal Golgi function (By similarity)

Gene Wiki entry for COG7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010393.16  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COG7 gene promoter:
         Egr-3   AhR   STAT5B   p53   AML1a   GCNF   Arnt   CREB   deltaCREB   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCOG7 promoter sequence
   Search SABiosciences Chromatin IP Primers for COG7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COG7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2   Ensembl cytogenetic band:  16p12.2   HGNC cytogenetic band: 16p12.2

COG7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COG7 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M023307:  view genomic region     (about GC identifiers)

Start:
23,399,814 bp from pter      End:
23,464,512 bp from pter
Size:
64,699 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: COG7_HUMAN, P83436 (See protein sequence)
Recommended Name: Conserved oligomeric Golgi complex subunit 7  
Size: 770 amino acids; 86344 Da
Subunit: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is
required for normal Golgi morphology and localization
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein
Sequence caution: Sequence=AAQ88995.1; Type=Erroneous initiation;
Secondary accessions: Q6UWU7

Explore the universe of human proteins at neXtProt for COG7: NX_P83436

Explore proteomics data for COG7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P83436

  • COG7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    COG7 Protein Expression
    REFSEQ proteins: NP_705831.1  
    ENSEMBL proteins: 
     ENSP00000305442   ENSP00000459872   ENSP00000460151  

    Human Recombinant Protein Products for COG7: 
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    OriGene Custom Protein Services for COG7
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    Novus Biologicals COG7 Protein
    Novus Biologicals COG7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for COG7 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005794Golgi apparatus IDA11980916
    GO:0017119Golgi transport complex IDA15047703

    COG7 for ontologies           About GeneDecksing



    COG7 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for COG7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    COG: Components of oligomeric golgi complex

    1 InterPro protein domain:
     IPR019335 COG7

    Graphical View of Domain Structure for InterPro Entry P83436

    ProtoNet protein and cluster: P83436

    UniProtKB/Swiss-Prot: COG7_HUMAN, P83436
    Similarity: Belongs to the COG7 family


    COG7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COG7_HUMAN, P83436
    Function: Required for normal Golgi function (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15047703
         
    COG7 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Cog7 (no phenotypes)

    COG7 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cog7tm1Lex for COG7

       inGenious Targeting Laboratory - Custom generated mouse model solutions for COG7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for COG7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for COG7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for COG7 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COG7
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate COG7:
    hsa-miR-27a hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidCOG7 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COG7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COG7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/13 Interacting proteins for COG7 (P834361, 2, 3 ENSP000003054424) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COG4Q9H9E31, 2, 3, ENSP000003157754EBI-389534,EBI-368382 MINT-7296787 MINT-7296769 MINT-7296817 MINT-7296802 I2D: score=3 STRING: ENSP00000315775
    SCFD1Q8WVM82, ENSP000003907834MINT-7296787 MINT-7296769 MINT-7296817 MINT-7296802 STRING: ENSP00000390783
    COG3Q96JB22, ENSP000002586544MINT-7296787 MINT-7296769 MINT-7296817 MINT-7296802 STRING: ENSP00000258654
    COG8Q96MW52, ENSP000003054594MINT-7296787 MINT-7296769 MINT-7296802 STRING: ENSP00000305459
    COG5Q9UP831, 3, ENSP000002971354EBI-389534,EBI-389502 I2D: score=3 STRING: ENSP00000297135
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IMP15107842
    GO:0006886intracellular protein transport IMP15107842
    GO:0006890retrograde vesicle-mediated transport, Golgi to ER IMP16420527
    GO:0033365protein localization to organelle IMP16420527
    GO:0034067protein localization to Golgi apparatus IMP16510524

    COG7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COG7

    Search CenterWatch for drugs/clinical trials and news about COG7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for COG7 gene: 
    NM_153603.3  

    Unigene Cluster for COG7:

    Component of oligomeric golgi complex 7
    Hs.185807  [show with all ESTs]
    Unigene Representative Sequence: AK126661
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307149(uc002dlo.3) ENST00000566364 ENST00000561854 ENST00000569635
    ENST00000563164 ENST00000567821
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COG7
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate COG7:
    hsa-miR-27a hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidCOG7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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                         Customized lentivirus expression plasmids for stable overexpression of COG7 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COG7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COG7

    Additional mRNA sequence: 

    AF070568.1 AK093989.1 AK126661.1 AK130714.1 AY358632.1 BC000549.2 BC037563.1 

    10 DOTS entries:

    DT.97794431  DT.448939  DT.99983615  DT.92005676  DT.95236516  DT.97782490  DT.91863922  DT.449616 
    DT.449618  DT.95197473 

    24/149 AceView cDNA sequences (see all 149):

    BC037563 AV746608 F11876 BI770126 BM701825 AA075965 BI050276 AL542757 
    BM821557 CA389470 BM464032 AA076126 BX362788 F12679 AW388114 AF070568 
    AA775076 BC000549 BF589842 AL710863 BG538729 BX478190 AY358632 BX372068 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for COG7 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b ^ 18a ·
    SP1:                                                              -                                         -                                   -     -         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                            -     -         
    SP4:                                                                                                                                                  -         
    SP5:              -                                                                                                                                             

    ExUns: 18b
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for COG7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COG7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGCCAGGAG
    COG7 Expression
    About this image


    See COG7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COG7

    SOURCE GeneReport for Unigene cluster: Hs.185807
        SABiosciences Custom PCR Arrays for COG7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COG7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for COG7 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cog71 , 5 component of oligomeric golgi complex 71, 5 88.05(n)1
    92.47(a)1
      7 (65.09 cM)5
    2338241  NM_001033318.31  NP_001028490.21 
     1219228395 
    chicken
    (Gallus gallus)
    Aves COG71 component of oligomeric golgi complex 7 74.84(n)
    79.01(a)
      416578  XM_001234079.2  XP_001234080.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    COG76
    Uncharacterized protein
    79(a)
    78(a)
    many → 1
    many → 1
    GL344322.1(1125-7021)
    AAWZ02036406(3371-27518)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339702 Xenopus laevis transcribed sequences 76.17(n)    BJ052096.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cog71 component of oligomeric golgi complex 7 66.88(n)
    70.8(a)
      768247  NM_001077393.1  NP_001070861.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cog71 CG31040-PA 43.65(n)
    30.13(a)
      43547  NM_143493.3  NP_651750.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons EYE1 golgi complex component-related protein 41.95(n)
    27.6(a)
      835217  NM_124522.3  NP_199956.1 


    ENSEMBL Gene Tree for COG7 (if available)
    TreeFam Gene Tree for COG7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1297 SNPs in COG7 are shown (see all 1297)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs346461441,2
    C--23405379(+) CTCAG-/AAAAAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs342192651,2
    C--23408237(+) TTTTC-/TTTTTT 1 -- int10--------
    rs343596021,2
    C--23410334(+) GCCAGC/-CCTGG 1 -- int11Minor allele frequency- -:0.00NA 2
    rs578012611,2
    C--23413667(+) TTTTT-/TGTATT 1 -- int11Minor allele frequency- T:0.00CSA 2
    rs351895661,2
    C--23419535(+) GGCAGG/TGGGCG 1 -- int11Minor allele frequency- T:0.50NA 2
    rs351457571,2
    C--23419539(+) GGGGGC/AGAGTG 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1851521,2
    C--23419591(-) ccgccC/Acactc 1 -- int11Minor allele frequency- A:0.50NA 2
    rs425341,2
    C--23419624(-) cccctG/Acctcc 1 -- int11Minor allele frequency- A:0.50NA 2
    rs423931,2
    C--23419675(-) actcgC/Tcccct 1 -- int11Minor allele frequency- T:0.50NA 2
    rs398161,2
    C,F--23419698(-) actcgC/Tcccct 1 -- int11Minor allele frequency- T:0.50NA 2

    HapMap Linkage Disequilibrium report for COG7 (23399814 - 23464512 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for COG7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv1768CNV Insertion18451855


    Human Gene Mutation Database (HGMD): COG7
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing COG7
    DNA2.0 Custom Variant and Variant Library Synthesis for COG7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606978   
    OMIM disorders: 608779  
    UniProtKB/Swiss-Prot: COG7_HUMAN, P83436
  • Congenital disorder of glycosylation 2E (CDG2E) [MIM:608779]: A multisystem disorder caused by a defect
    in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of
    glycosylation result in a wide variety of clinical features, such as defects in the nervous system development,
    psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad
    spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation,
    and maintenance of cell functions. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 6 diseases for COG7:    About MalaCards
    congenital disorder of glycosylation type 2e    congenital disorder of glycosylation    menkes disease    cutis laxa
    hypotonia    microcephaly

    2 diseases from the University of Copenhagen DISEASES database for COG7:
    Congenital disorder of glycosylation     Cutis laxa

    COG7 for disorders           About GeneDecksing

    GeneTests: COG7
    GeneReviews: COG7

    Export disorders for COG7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COG7 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with COG7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. (PubMed id 11980916)1, 2, 3 Ungar D....Waters M.G. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder. (PubMed id 15107842)1, 2 Wu X.... Freeze H.H. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. A common mutation in the COG7 gene with a consistent phenotype including microcephaly, adducted thumbs, growth retardation, VSD and episodes of hyperthermia. (PubMed id 17356545)1, 9 Morava E....Wevers R.A. (2007)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    9. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)1 Neganova I....Lako M. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91949 HGNC: 18622 AceView: COG7 Ensembl:ENSG00000168434 euGenes: HUgn91949
    ECgene: COG7 H-InvDB: COG7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COG7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for COG7 gene:
    Search GeneIP for patents involving COG7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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