Aliases for COG6 Gene
Aliases for COG6 Gene
External Ids for COG6 Gene
- HGNC: 18621
- Entrez Gene: 57511
- Ensembl: ENSG00000133103
- OMIM: 606977
- UniProtKB: Q9Y2V7
Previous GeneCards Identifiers for COG6 Gene
- GC13P038216
- GC13P034216
- GC13P039166
- GC13P038027
- GC13P039127
- GC13P040229
- GC13P021028
Summaries for COG6 Gene
-
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
GeneCards Summary for COG6 Gene
COG6 (Component Of Oligomeric Golgi Complex 6) is a Protein Coding gene. Diseases associated with COG6 include Congenital Disorder Of Glycosylation, Type Iil and Shaheen Syndrome. Among its related pathways are Intra-Golgi traffic and Vesicle-mediated transport.
UniProtKB/Swiss-Prot for COG6 Gene
-
Required for normal Golgi function.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COG6 Gene
Genomics for COG6 Gene
Regulatory Elements for COG6 Gene
Enhancers for COG6 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH13G039655 | 1 | ENCODE | 61.6 | +0.2 | 170 | 1.6 | CREB3L1 ARID4B SIN3A DMAP1 GLI4 ZNF48 YY1 ETS1 GLIS2 GATA2 | COG6 MIR4305 |
| GH13G039775 | 1.5 | FANTOM5 Ensembl ENCODE | 23.4 | +121.7 | 121724 | 3.9 | ELF3 PKNOX1 DMAP1 RAD21 YY1 RARA GATA2 SCRT2 RCOR1 FOS | COG6 ENSG00000212553 GC13P039785 GC13P039748 |
| GH13G039810 | 1 | Ensembl ENCODE | 11.2 | +155.5 | 155458 | 0.9 | CTCF MAX GLI4 FEZF1 SALL2 RAD21 ZNF644 ZNF335 ZNF366 NR2F6 | COG6 ENSG00000212553 NHLRC3 CDKN2AIPNLP3 GC13M039786 RNY4P14 |
| GH13G039801 | 0.7 | ENCODE | 9.4 | +147.5 | 147505 | 2.4 | PKNOX1 RFX1 NFIB MNT DPF2 ZNF592 FOXA1 CTBP1 GATA3 POLR2A | ENSG00000212553 COG6 CDKN2AIPNLP3 GC13M039786 RNY4P14 |
| GH13G039809 | 0.5 | ENCODE | 12.3 | +154.2 | 154226 | 0.6 | RCOR2 ZMYM3 KDM1A ZNF48 | COG6 ENSG00000212553 CDKN2AIPNLP3 RNY4P14 GC13M039786 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around COG6 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for COG6 Gene
- Chromosome:
- 13
- Start:
- 39,655,627 bp from pter
- End:
- 39,791,665 bp from pter
- Size:
- 136,039 bases
- Orientation:
- Plus strand
Genomic View for COG6 Gene
Genes around COG6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q14.11 by Ensembl
- 13q14.11 by Entrez Gene
- 13q14.11 by HGNC
COG6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for COG6 Gene
Proteins for COG6 Gene
-
Protein details for COG6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2V7-COG6_HUMAN
- Recommended name:
- Conserved oligomeric Golgi complex subunit 6
- Protein Accession:
- Q9Y2V7
- Q5T0U1
- Q6AI19
- Q86V49
- Q9ULT5
Protein attributes for COG6 Gene
- Size:
- 657 amino acids
- Molecular mass:
- 73279 Da
- Quaternary structure:
-
- Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
- SequenceCaution:
-
- Sequence=AAD29633.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Protein Expression for COG6 Gene
Post-translational modifications for COG6 Gene
Other Protein References for COG6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for COG6
- TA344768
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- CF505449
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- CF505623
- TA505418AM
- TA505418BM
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- TA505418DM
- TA505418EM
- TA505418FM
- TA505418GM
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- TA505449FM
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- TA505531CM
- TA505531DM
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- TA505623AM
- TA505623BM
- TA505623CM
- TA505623DM
- TA505623EM
- TA505623FM
- TA505623GM
- TA505623HM
- TA505623JM
- Novus Biologicals Antibodies for COG6
- Invitrogen Antibodies for COG6
- antibodies-online Antibodies for COG6: See all 20
- Search GeneTex for Antibodies for COG6
-
Santa Cruz Biotechnology (SCBT) Antibodies for COG6
Protein Products
-
OriGene Purified Proteins for COG6
- Search Origene for MassSpec and Protein Over-expression Lysates for COG6
- Origene Custom Protein Services for COG6
- antibodies-online Proteins for COG6: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for COG6
Assay Products
No data available for DME Specific Peptides for COG6 Gene
Domains & Families for COG6 Gene
Gene Families for COG6 Gene
Protein Domains for COG6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for COG6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y2V7- Family:
-
- Belongs to the COG6 family.
Function for COG6 Gene
Molecular function for COG6 Gene
- UniProtKB/Swiss-Prot Function:
- Required for normal Golgi function.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 27107012 |
Phenotypes for COG6 Gene
- MGI mutant phenotypes for COG6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for COG6:
Animal Models for COG6 Gene
- MGI Knock Outs for COG6:
-
- Cog6 tm1a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for COG6
-
-
ViGene Biosciences lentiviral particle packaged cDNA for COG6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for COG6 gene
- Search ViGene Biosciences for COG6
CRISPR Products
-
OriGene CRISPR knockouts for COG6
-
Santa Cruz Biotechnology (SCBT) CRISPR for COG6
- GenScript: Design CRISPR guide RNA sequences for COG6
miRNA for COG6 Gene
- miRTarBase miRNAs that target COG6
-
- hsa-mir-875-5p (MIRT630740)
- hsa-mir-874-3p (MIRT630741)
- hsa-mir-3157-3p (MIRT630742)
- hsa-mir-4777-3p (MIRT630743)
- hsa-mir-19b-2-5p (MIRT630744)
- hsa-mir-19b-1-5p (MIRT630745)
- hsa-mir-19a-5p (MIRT630746)
- hsa-mir-3613-5p (MIRT630747)
- hsa-mir-18b-3p (MIRT630748)
- hsa-mir-4328 (MIRT630749)
- hsa-mir-4781-3p (MIRT630750)
- hsa-mir-6809-3p (MIRT640419)
- hsa-mir-6833-3p (MIRT640420)
- hsa-mir-6873-3p (MIRT640421)
- hsa-mir-4768-5p (MIRT640422)
- hsa-mir-627-3p (MIRT640423)
- hsa-mir-6817-3p (MIRT640424)
- hsa-mir-7110-3p (MIRT640425)
- hsa-mir-6845-3p (MIRT640426)
- hsa-mir-5003-3p (MIRT640427)
- hsa-mir-34b-3p (MIRT640428)
- hsa-mir-551b-5p (MIRT640429)
miRNA Products
- Search ViGene Biosciences for COG6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for COG6
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-
ViGene Biosciences ready-to-package AAV shRNAs for COG6 gene
Clone Products
- Sino Biological Human cDNA Clone for COG6
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- VectorBuilder custom plasmid, inducible vectors for COG6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for COG6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for COG6
-
ViGene Biosciences adenoviral particle packaged cDNA for COG6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for COG6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for COG6 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for COG6 Gene
Localization for COG6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for COG6 Gene
- Golgi apparatus membrane; Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| nucleus | 3 |
| cytosol | 3 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0017119 | Golgi transport complex | IEA,IDA | 15047703 |
| GO:0032588 | trans-Golgi network membrane | TAS | -- |
Pathways & Interactions for COG6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport to the Golgi and subsequent modification | ||
| 2 | Vesicle-mediated transport | ||
| 3 | Metabolism of proteins | ||
| 4 | Golgi-to-ER retrograde transport | ||
| 5 | Intra-Golgi traffic | ||
Pathways by source for COG6 Gene
Interacting Proteins for COG6 Gene
Selected Interacting proteins:
ENSP00000397441
Q9Y2V7-COG6_HUMAN
for COG6 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | -- |
| GO:0006891 | intra-Golgi vesicle-mediated transport | IEA,IBA | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:0070085 | glycosylation | IMP | 20605848 |
No data available for SIGNOR curated interactions for COG6 Gene
Transcripts for COG6 Gene
mRNA/cDNA for COG6 Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (100) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for COG6 Gene
- Component of oligomeric golgi complex 6:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for COG6
-
Santa Cruz Biotechnology (SCBT) CRISPR for COG6
- GenScript: Design CRISPR guide RNA sequences for COG6
miRNA Products
- Search ViGene Biosciences for COG6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for COG6
- Browse OriGene Inhibitory RNA Products For COG6
-
ViGene Biosciences ready-to-package AAV shRNAs for COG6 gene
Clone Products
- Sino Biological Human cDNA Clone for COG6
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for COG6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for COG6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Expression for COG6 Gene
This gene is overexpressed in Bone (59.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for COG6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of COG6 Gene:
COG6SOURCE GeneReport for Unigene cluster for COG6 Gene:
Hs.507805Evidence on tissue expression from TISSUES for COG6 Gene
- Nervous system(4.8)
- Skin(4.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for COG6 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- cardiovascular
- integumentary
- nervous
- skeleton
Organs:
Head and neck:
- brain
- ear
- head
- jaw
- mandible
- maxilla
- mouth
- skull
- tooth
Thorax:
- heart
Limb:
- foot
- hand
- lower limb
- upper limb
General:
- blood vessel
- skin
- sweat gland
Primer Products
-
OriGene qPCR primer pairs and template standards for COG6
-
OriGene qPCR primer pairs for COG6
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for COG6 Gene
Orthologs for COG6 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | COG6 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | COG6 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | COG6 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | COG6 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | COG6 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cog6 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cog6 34 16 35 |
|
||
| chicken (Gallus gallus) |
Aves | COG6 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | COG6 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cog6 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC68662 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cog6 35 |
|
OneToOne | |
| -- 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007586 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1968 36 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | K07C11.9 36 |
|
|
|
| cogc-6 35 |
|
OneToOne | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | COG6 35 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G31780 34 |
|
||
| barley (Hordeum vulgare) |
Liliopsida | Hv.10396 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os.43918 34 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.12037 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.15593 34 |
|
- Species where no ortholog for COG6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for COG6 Gene
No data available for Paralogs for COG6 Gene
Variants for COG6 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs387906959 | Pathogenic, Congenital disorder of glycosylation 2L (CDG2L) [MIM:614576] | 39,723,394(+) | GGTAG(C/G/T)CTTGA | nc-transcript-variant, reference, missense | |
| rs730882236 | Pathogenic | 39,699,477(+) | TTGCA(A/G)CCTGA | intron-variant | |
| rs781641023 | Pathogenic | 39,694,633(+) | TAATA(A/G/T)GTTCG | splice-acceptor-variant | |
| rs794726950 | Pathogenic | 39,655,838(+) | CGCGC(A/T)AGCTG | nc-transcript-variant, reference, stop-gained | |
| rs142947196 | Likely benign | 39,751,408(+) | AAGAA(-/T)TTTTT | intron-variant, nc-transcript-variant, utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1608257 | CNV | insertion | 17803354 |
| esv33028 | CNV | gain | 17666407 |
| esv3631837 | CNV | gain | 21293372 |
| nsv1012 | CNV | insertion | 18451855 |
| nsv1054600 | CNV | gain | 25217958 |
| nsv471130 | CNV | loss | 18288195 |
| nsv472047 | CNV | novel sequence insertion | 20440878 |
| nsv523666 | CNV | loss | 19592680 |
| nsv832586 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
30.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
20.24;
99.05% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for COG6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COG6 Gene
Disorders for COG6 Gene
(7) MalaCards diseases for COG6 Gene - From: OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| congenital disorder of glycosylation, type iil |
|
|
| shaheen syndrome |
|
|
| hypohidrosis |
|
|
| congenital disorder of glycosylation, type iih |
|
|
| corneal dystrophy, posterior amorphous |
|
|
Search COG6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
COG6_HUMAN- Congenital disorder of glycosylation 2L (CDG2L) [MIM:614576]: A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Clinical features of CDG2L include neonatal intractable focal seizures, vomiting, loss of consciousness, intracranial bleeding due to vitamin K deficiency, and death in infancy. {ECO:0000269 PubMed:20605848}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Shaheen syndrome (SHNS) [MIM:615328]: An autosomal recessive form of syndromic mental retardation. Affected individuals show severe intellectual disability, hypohidrosis, dental enamel hypoplasia, and hyperkeratosis of the palms and soles. Some may develop mild microcephaly. {ECO:0000269 PubMed:23606727}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for COG6
No data available for Genatlas for COG6 Gene
Publications for COG6 Gene
- A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. (PMID: 18369459) Liu Y. … Bowcock A.M. (PLoS Genet. 2008) 3 22 46 64
- Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. (PMID: 11980916) Ungar D. … Waters M.G. (J. Cell Biol. 2002) 2 3 4 64
- A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency. (PMID: 23606727) Shaheen R. … Alkuraya F.S. (J. Med. Genet. 2013) 3 4 64
- Fatal outcome due to deficiency of subunit 6 of the conserved oligomeric Golgi complex leading to a new type of congenital disorders of glycosylation. (PMID: 20605848) Lubbehusen J. … Korner C. (Hum. Mol. Genet. 2010) 3 4 64
- Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 3 4 64
Products for COG6 Gene
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- Browse R&D Systems for biochemical assays
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- Custom Antibody ServicesOriGene Antibodies for COG6
- TA344768
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- CF505531
- TA505623
- CF505623
- TA505418AM
- TA505418BM
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- TA505623HM
- TA505623JM
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for COG6
- Search Origene for MassSpec and Protein Over-expression Lysates for COG6
- Origene Custom Protein Services for COG6
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for COG6
- Browse OriGene Inhibitory RNA Products For COG6
- OriGene qPCR primer pairs and template standards for COG6
- OriGene qPCR primer pairs for COG6
- OriGene CRISPR knockouts for COG6
- OriGene ORF clones in human for COG6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For COG6
- GenScript: Next-day shipping cDNA ORF clone for COG6 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for COG6
- GenScript Custom Assay Services for COG6
- GenScript Custom overexpressing Cell Line Services for COG6
- GenScript: Design CRISPR guide RNA sequences for COG6
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for COG6
- Sino Biological Human cDNA Clone for COG6
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for COG6
- Novus Biologicals proteins and lysates for COG6
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for COG6: See all 20
- Search antibodies-online for kits
- antibodies-online Proteins for COG6: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for COG6
- Search GeneTex for Proteins for COG6
- ViGene Biosciences adenoviral particle packaged cDNA for COG6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for COG6 gene
- ViGene Biosciences ready-to-package AAV shRNAs for COG6 gene
- Search ViGene Biosciences for COG6
- Santa Cruz Biotechnology (SCBT) Antibodies for COG6
- Search Santa Cruz Biotechnology (SCBT) for COG6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for COG6
- Horizon Cell Lines for COG6
- Cyagen custom Knockout/knockin (KOKI) mouse models for COG6
- VectorBuilder custom plasmid, inducible vectors for COG6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for COG6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for COG6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
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- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer