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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

COG5 Gene

protein-coding   GIFtS: 52
GCID: GC07M106842

component of oligomeric golgi complex 5

(Previous name: golgi transport complex 1 (90 kDa subunit) )
(Previous symbol: GOLTC1)
 Explore 7 diseases affiliated with
COG5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for COG5    

Aliases
for COG5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Component Of Oligomeric Golgi Complex 51 2 3     13S Golgi Transport Complex 1 90 KDa Subunit2
GOLTC11 2 3 5     Conserved Oligomeric Golgi Complex Protein 52
GTC901 2 3 5     Conserved Oligomeric Golgi Complex Subunit 52
COG Complex Subunit 52 3     13S Golgi Transport Complex 90 KDa Subunit3
CDG2I2 5     GTC-903
Golgi Transport Complex 1 (90 KDa Subunit)1     Golgi Transport Complex 13

External Ids:    HGNC: 148571   Entrez Gene: 104662   Ensembl: ENSG000001645977   OMIM: 6068215   UniProtKB: Q9UP833   

Export aliases for COG5 gene to outside databases

Previous GC identifers: GC07M105326 GC07M106389 GC07M106403 GC07M106436 GC07M106630 GC07M101202


Summaries
for COG5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for COG5:
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required
for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex
components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript
variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.(provided by RefSeq, Jan 2011)

UniProtKB/Swiss-Prot: COG5_HUMAN, Q9UP83
Function: Required for normal Golgi function (By similarity)

Gene Wiki entry for COG5


Genomic Views
for COG5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the COG5 gene promoter:
         Nkx3-1   Nkx3-1 v4   NCX/Ncx   Nkx3-1 v1   Tal-1beta   Gfi-1   E47   FOXL1   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): COG5 promoter sequence
   Search SABiosciences Chromatin IP Primers for COG5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat COG5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31   Ensembl cytogenetic band:  7q22.3   HGNC cytogenetic band: 7q31

COG5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
COG5 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M106842:  view genomic region     (about GC identifiers)

Start:
 106,842,189 bp from pter      End:
 107,204,959 bp from pter
Size:
 362,771 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 106,203,276-106,566,048     

Proteins
for COG5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: COG5_HUMAN, Q9UP83 (See protein sequence)
Recommended Name: Conserved oligomeric Golgi complex subunit 5  
Size: 839 amino acids; 92743 Da
Subunit: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is
required for normal Golgi morphology and localization (By similarity)
Subcellular location: Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein
Caution: It is uncertain whether Met-1 or Met-32 is the initiator
Secondary accessions: A4D0R6 A4D0R7 O14555 O95008 Q6NUL5
Alternative splicing: 3 isoforms:  Q9UP83-1   Q9UP83-2   Q9UP83-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for COG5: NX_Q9UP83

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UP83

    • COG5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001154992.1  NP_006339.3  NP_859422.2  

    ENSEMBL proteins: 
     ENSP00000334703   ENSP00000297135   ENSP00000377228  

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    Uscn Proteins for COG5

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0005829cytosol IEA--


    COG5 for ontologies           About GeneDecksing



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    ThermoFisher Antibodies for COG5

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    Uscn ELISAs and CLIAs for COG5

    Protein Domains /
    Families
    for COG5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    COG5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019465 Cog5

    Graphical View of Domain Structure for InterPro Entry Q9UP83

    ProtoNet protein and cluster: Q9UP83

    UniProtKB/Swiss-Prot: COG5_HUMAN, Q9UP83
    Similarity: Belongs to the COG5 family


    Function
    for COG5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: COG5_HUMAN, Q9UP83
    Function: Required for normal Golgi function (By similarity)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COG5
    8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate COG5 (see all 78):
    hsa-miR-411* hsa-miR-3607-3p hsa-miR-607 hsa-miR-15a hsa-miR-1258 hsa-miR-578 hsa-miR-3921 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmid: COG5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COG5
    OriGene shRNA RFP: COG5
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COG5

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for COG5 (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COG5 

    Cell Line
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    Search LifeMap BioReagents cell lines for COG5

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COG5

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI15047703


    COG5 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for COG5:
     Increased G1 DNA content  Increased HPV18 LCR reporter a 


    Pathways & Interactions
    for COG5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for COG5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/18 Interacting proteins for COG5 (Q9UP831, 3 ENSP000002971354) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COG4Q9H9E31, 3, ENSP000003157754EBI-389502,EBI-368382 I2D: score=3 STRING: ENSP00000315775
    COG7P834361, 3, ENSP000003054424EBI-389502,EBI-389534 I2D: score=3 STRING: ENSP00000305442
    APCP250543, ENSP000002574304I2D: score=3 STRING: ENSP00000257430
    MEFVO155533, ENSP000002195964I2D: score=2 STRING: ENSP00000219596
    TRAF5O004633, ENSP000002614644I2D: score=1 STRING: ENSP00000261464
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006891intra-Golgi vesicle-mediated transport NAS9792665
    GO:0015031protein transport IEA--


    COG5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for COG5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for COG5
    Search CenterWatch for drugs/clinical trials and news about COG5 

    Transcripts
    for COG5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for COG5 gene (3 alternative transcripts): 
    NM_001161520.1  NM_006348.3  NM_181733.2  

    Unigene Cluster for COG5:

    Component of oligomeric golgi complex 5
    Hs.239631  [show with all ESTs]
    Unigene Representative Sequence: NM_001161520
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000347053(uc003vec.2 uc003ved.2) ENST00000297135 ENST00000393603(uc003vee.2)
    ENST00000464542 ENST00000468350 ENST00000462342 ENST00000484237 ENST00000475638
    ENST00000468056 ENST00000469503

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat COG5
    8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate COG5 (see all 78):
    hsa-miR-411* hsa-miR-3607-3p hsa-miR-607 hsa-miR-15a hsa-miR-1258 hsa-miR-578 hsa-miR-3921 hsa-miR-3122
    SwitchGear 3'UTR luciferase reporter plasmid: COG5 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for COG5
    OriGene shRNA RFP: COG5
    OriGene siRNA: COG5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat COG5
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): COG5 (NM_006348)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat COG5 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat COG5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat COG5

    Additional cDNA sequence: 

    AF058718.1 AK022835.1 AK123726.1 AK126275.1 AK314270.1 BC068540.1 

    20 DOTS entries:

    DT.95112747  DT.100877360  DT.91889224  DT.100877357  DT.102836928  DT.100877367  DT.207394  DT.121103104 
    DT.319613  DT.427564  DT.121102934  DT.40107938  DT.121103107  DT.95218311  DT.100000135  DT.100877361 
    DT.121102981  DT.40130508  DT.95175981  DT.95304157 

    24/251 AceView cDNA sequences (see all 251):

    AA347084 BQ230813 AA373937 CR620007 AA723054 CN483343 BI962862 AA564907 
    CB053996 AI089573 AA193604 AI274016 CB160916 AI886707 AW130049 AI167490 
    AA281598 BP345988 CA434070 Z39236 BM852381 AK123726 AA189142 AA926962 

    GeneLoc Exon Structure


    Expression
    for COG5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    COG5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCCTTAGCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See COG5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for COG5

    SOURCE GeneReport for Unigene cluster: Hs.239631
        SABiosciences Custom PCR Arrays for COG5
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for COG5

    Orthologs
    for COG5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for COG5 gene from 9/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cog51 , 5 component of oligomeric golgi complex 51, 5 87.86(n)1
    89.26(a)1    		   12 (13.68 cM)5
    2381231  NM_001163126.11  NP_001156598.11 
     316548695 
    chicken
    (Gallus gallus)    		 Aves COG51 component of oligomeric golgi complex 5 79.42(n)
    86.35(a)    		   417704  NM_001199445.1  NP_001186374.1 
    lizard
    (Anolis carolinensis)    		 Reptilia COG56
    		 --
    		 85(a)
    		 1 ↔ 1
    		 5(97288956-97513090)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.152542 Xenopus laevis transcribed sequence with weak similarity to protein refNP_006339.1 (H.sapiens) component of oligomeric golgi complex 5; golgi transport complex 1 (90 kDa subunit); conserved oligomeric Golgi complex protein 5 [Homo sapiens] less 76.65(n)    BQ732577.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii cog51 component of oligomeric golgi complex 5 69.12(n)
    78.43(a)    		   567886  NM_001045144.1  NP_001038609.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta fws3   -- 25(a)   2 36C10   --
    worm
    (Caenorhabditis elegans)    		 Secernentea cogc-51 Protein COGC-5 42.32(n)
    28.7(a)    		   172025  NM_058938.4  NP_491339.2 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G679301 Golgi transport complex-related protein 44.2(n)
    32.99(a)    		   843121  NM_105463.3  NP_176960.1 
    rice
    (Oryza sativa)    		 Liliopsida Os05g03789001 hypothetical protein 41.79(n)
    30.85(a)    		   4338625  NM_001061925.1  NP_001055390.1 


    ENSEMBL Gene Tree for COG5 (if available)
    TreeFam Gene Tree for COG5 (if available) 

    Paralogs
    for COG5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for COG5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5980 NCBI SNPs in COG5 are shown (see all 5980)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs69529281,2
    		C--106203633(+) AGGCCA/GAGGTA 2 -- ut312Minor allele frequency- G:0.00NA 4
    rs150021,2
    		C,F,H--106204384(+) CAAAAG/ACCTTG 2 -- ut31 ese38Minor allele frequency- A:0.01MN EA NS NA 1138
    rs69581371,2
    		C,F,H,--106204436(+) TTAACC/GTTGTA 2 -- ut31 ese35Minor allele frequency- G:0.01NS EA WA 538
    rs1149155661,2
    		C,F,--106204524(+) ATAGTG/AGTGTC 2 -- ut311Minor allele frequency- A:0.02WA 118
    rs69584941,2
    		C,F,H,--106204755(+) TACCCA/GTAGGA 2 -- ut31 ese39Minor allele frequency- G:0.01NS EA NA 1094
    rs765960891,2
    		C,F,--106205877(+) AGAGAC/TCATGT 2 -- int11Minor allele frequency- T:0.02WA 118
    rs744393381,2
    		F,--106206045(+) TTGTCA/GTATTT 2 -- int11Minor allele frequency- G:0.14WA 118
    rs731873221,2
    		--106206246(+) CACTGA/CTCAGT 2 -- int10--------
    rs777580621,2
    		--106206332(+) CTCCCC/TCTCCT 2 -- int10--------
    rs1902440681,2
    		C,--106206420(+) ATTGGA/GGCAGC 2 -- int10--------

    HapMap Linkage Disequilibrium report for COG5 (106842189 - 107092189 bp, first 250kb of COG5)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for COG5
         2 CNVs: 94794 59374
         6 Inversions: 37277 29420 37278 29403 29418 103373
    Human Gene Mutation Database (HGMD): COG5

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing COG5
    DNA2.0 Custom Variant and Variant Library Synthesis for COG5

    Disorders / Diseases
    for COG5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    COG5 for disorders           About GeneDecksing

    OMIM gene information: 606821   
    OMIM disorders: 613612  
    UniProtKB/Swiss-Prot: COG5_HUMAN, Q9UP83
  • Defects in COG5 are the cause of congenital disorder of glycosylation type 2I (CDG2I) [MIM:613612]. A
    • multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum
    glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in
    the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and
    immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic
    development, differentiation, and maintenance of cell functions. Congenital disorder of glycosylation type 2I is
    characterized by mild neurological impairments

    7 diseases for COG5:    About MalaCards
    congenital disorder of glycosylation    familial mediterranean fever    microcephaly    hypotonia
    leiomyoma    osteoarthritis    neuroblastoma

    1 disease from the University of Copenhagen DISEASES database for COG5:
    Congenital disorder of glycosylation
    Human Genome Epidemiology (HuGE) Navigator: COG5 (2 documents)

    Export disorders for COG5 gene to outside databases

    Publications
    for COG5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for COG5 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with COG5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Purification and characterization of a novel 13 S hetero-oligomeric protein complex that stimulates in vitro Golgi transport. (PubMed id 9792665)1, 2, 3 Walter D.M.... Waters M.G. (1998)
    2. Deficiency in COG5 causes a moderate form of congenit al disorders of glycosylation. (PubMed id 19690088)1, 2, 9 Paesold-Burda P....Hennet T. (2009)
    3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    4. Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. (PubMed id 11980916)1, 3 Ungar D....Waters M.G. (2002)
    5. The familial mediterranean fever protein interacts and colocalizes with a putative Golgi transporter. (PubMed id 10782044)1, 9 Chen X....Fischel-Ghodsian N. (2000)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. Genetic contribution to radiographic severity in osteo arthritis of the knee. (PubMed id 22615457)1 Valdes A.M....Doherty M. (2012)
    10. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)

    External Searches for COG5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing COG5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10466 HGNC: 14857 AceView: COG5 Ensembl:ENSG00000164597 euGenes: HUgn10466
    ECgene: COG5 H-InvDB: COG5

    Other Databases showing COG5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing COG5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for COG5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for COG5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for COG5 gene:
    Search GeneIP for patents involving COG5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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