Aliases for COG4 Gene
External Ids for COG4 Gene
Previous GeneCards Identifiers for COG4 Gene
The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
GeneCards Summary for COG4 Gene
COG4 (Component Of Oligomeric Golgi Complex 4) is a Protein Coding gene. Diseases associated with COG4 include Congenital Disorder Of Glycosylation, Type Iij and Congenital Disorder Of Glycosylation, Type Ii. Among its related pathways are Intra-Golgi traffic and Vesicle-mediated transport.
UniProtKB/Swiss-Prot for COG4 Gene
Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.