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Aliases for COASY Gene

Aliases for COASY Gene

  • Coenzyme A Synthase 2 3 5
  • CoA Synthase 2 3 4
  • POV-2 3 4
  • NBP 3 4
  • Bifunctional Phosphopantetheine Adenylyl Transferase/Dephospho CoA Kinase 3
  • Phosphopantetheine Adenylyltransferase / Dephosphocoenzyme A Kinase 3
  • Bifunctional Coenzyme A Synthase 3
  • Nucleotide Binding Protein 3
  • NBIA6 3
  • DPCK 3
  • PPAT 3
  • UKR1 3

External Ids for COASY Gene

Previous GeneCards Identifiers for COASY Gene

  • GC17P041088
  • GC17P037967
  • GC17P040714
  • GC17P036478

Summaries for COASY Gene

Entrez Gene Summary for COASY Gene

  • Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. [provided by RefSeq, Apr 2014]

GeneCards Summary for COASY Gene

COASY (Coenzyme A Synthase) is a Protein Coding gene. Diseases associated with COASY include Neurodegeneration With Brain Iron Accumulation 6 and Coasy-Associated Neurodegeneration. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include dephospho-CoA kinase activity and pantetheine-phosphate adenylyltransferase activity.

UniProtKB/Swiss-Prot for COASY Gene

  • Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.

Gene Wiki entry for COASY Gene

Additional gene information for COASY Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COASY Gene

Genomics for COASY Gene

Regulatory Elements for COASY Gene

Enhancers for COASY Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H041649 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -906.8 -906822 9.8 HDGF ARNT ZNF133 YBX1 BRCA1 TCF12 GLIS2 ZNF207 ATF7 RUNX3 ENSG00000267758 JUP HSD17B1 DHX58 GHDC ENSG00000259623 KRT14 CNP PSMC3IP RETREG3
GH17H043366 1.7 Ensembl ENCODE dbSUPER 11.1 +807.2 807248 4 HNRNPUL1 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 DHX8 NBR2 HMGN1P29 ASB16-AS1 LINC00910 TMUB2 UBTF ENSG00000267340 PSME3 NBR1
GH17H042535 1.7 FANTOM5 ENCODE dbSUPER 10.8 -24.9 -24868 3.1 HDGF MLX ARNT ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF766 ZNF207 ENSG00000267340 PLEKHH3 MLX HMGN1P29 NBR2 NAGLU ENSG00000267002 PSMC3IP DHX58 RNU7-97P
GH17H043322 1.7 Ensembl ENCODE dbSUPER 10.5 +761.7 761696 1.6 MLX ZFP64 YBX1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 NFYC ENSG00000267340 UBTF ASB16-AS1 ENSG00000267002 DHX8 HMGN1P29 TMUB2 NBR2 PLEKHH3 LINC00910
GH17H042623 1.5 Ensembl ENCODE dbSUPER 11.3 +62.7 62737 1.9 PKNOX1 ATF1 ARNT TCF12 GTF3C2 ZNF766 GATA2 ZNF143 ATF7 FOS DHX8 TUBG2 HMGN1P29 VPS25 RETREG3 PSME3 COASY ENSG00000267758 LINC00910 WNK4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around COASY on UCSC Golden Path with GeneCards custom track

Promoters for COASY Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000094428 933 1201 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1

Genomic Locations for COASY Gene

Genomic Locations for COASY Gene
chr17:42,561,467-42,566,281
(GRCh38/hg38)
Size:
4,815 bases
Orientation:
Plus strand
chr17:40,713,485-40,718,295
(GRCh37/hg19)

Genomic View for COASY Gene

Genes around COASY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
COASY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for COASY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for COASY Gene

Proteins for COASY Gene

  • Protein details for COASY Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13057-COASY_HUMAN
    Recommended name:
    Bifunctional coenzyme A synthase
    Protein Accession:
    Q13057
    Secondary Accessions:
    • B2RA78
    • B4DLU0
    • Q6GS23
    • Q8NBM7
    • Q8NEW1
    • Q8WXD4
    • Q9NRM3

    Protein attributes for COASY Gene

    Size:
    564 amino acids
    Molecular mass:
    62329 Da
    Quaternary structure:
    • Monomer.
    SequenceCaution:
    • Sequence=AAA69699.1; Type=Frameshift; Positions=535; Evidence={ECO:0000305}; Sequence=AAF87955.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH06354.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH20985.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AK075415; Type=Frameshift; Positions=315; Evidence={ECO:0000305};

    Alternative splice isoforms for COASY Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for COASY Gene

Post-translational modifications for COASY Gene

  • Ubiquitination at Lys235 and posLast=554554
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for COASY Gene

Domains & Families for COASY Gene

Gene Families for COASY Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted secreted proteins

Suggested Antigen Peptide Sequences for COASY Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13057

UniProtKB/Swiss-Prot:

COASY_HUMAN :
  • In the central section; belongs to the eukaryotic CoaD family.
Family:
  • In the central section; belongs to the eukaryotic CoaD family.
genes like me logo Genes that share domains with COASY: view

Function for COASY Gene

Molecular function for COASY Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=7.6 mM for 4-phoshopantetheine; KM=145 mM for ATP (in the PPAT reaction); KM=16.7 mM for dephospho-CoA; KM=34.4 mM for ATP (in the DPCK reaction);
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + pantetheine 4-phosphate = diphosphate + 3-dephospho-CoA.
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + 3-dephospho-CoA = ADP + CoA.
UniProtKB/Swiss-Prot Function:
Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.

Phenotypes From GWAS Catalog for COASY Gene

Gene Ontology (GO) - Molecular Function for COASY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
GO:0004140 dephospho-CoA kinase activity TAS --
GO:0004595 pantetheine-phosphate adenylyltransferase activity TAS --
GO:0005515 protein binding IPI 15589845
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with COASY: view
genes like me logo Genes that share phenotypes with COASY: view

Human Phenotype Ontology for COASY Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

Clone Products

  • Addgene plasmids for COASY

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for COASY Gene

Localization for COASY Gene

Subcellular locations from UniProtKB/Swiss-Prot for COASY Gene

Cytoplasm. Mitochondrion matrix. Note=The protein is mainly present in the mitochondrial matrix, probably anchored to the inner mitochondrial membrane, but is also present in cell lysate.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for COASY gene
Compartment Confidence
extracellular 5
mitochondrion 5
cytosol 4
nucleus 3
peroxisome 2
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for COASY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion IEA --
GO:0005741 mitochondrial outer membrane TAS --
GO:0005759 mitochondrial matrix IDA,IEA 24360804
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with COASY: view

Pathways & Interactions for COASY Gene

genes like me logo Genes that share pathways with COASY: view

UniProtKB/Swiss-Prot Q13057-COASY_HUMAN

  • Pathway: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.
  • Pathway: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.

Gene Ontology (GO) - Biological Process for COASY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
GO:0009058 biosynthetic process IEA --
GO:0009108 coenzyme biosynthetic process TAS --
GO:0015937 coenzyme A biosynthetic process TAS 11994049
GO:0016310 phosphorylation IEA --
genes like me logo Genes that share ontologies with COASY: view

No data available for SIGNOR curated interactions for COASY Gene

Drugs & Compounds for COASY Gene

(3) Drugs for COASY Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
ATP Nutra Agonist 0
Coenzyme A Nutra 0

(7) Additional Compounds for COASY Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
Dephospho-CoA
  • 3'-Dephospho-CoA
  • 3'-Dephospho-Coenzyme A
  • 3'-O-Dephosphono-CoA
  • 3'-O-Dephosphono-Coenzyme A
  • Dephospho-CoA
3633-59-8
Pantetheine 4'-phosphate
  • 4'-Phosphopantetheine
  • 4'-Phosphopantotheine
  • D-Pantetheine 4'-phosphate
  • Pantetheine 4'-phosphate
  • Pantotheine-4'-phosphate
2226-71-3
pyrophosphate
  • (4-)Diphosphoric acid ion
  • (P2O74-)Diphosphate
  • Diphosphate
  • Diphosphoric acid
  • PPi
14000-31-8
genes like me logo Genes that share compounds with COASY: view

Transcripts for COASY Gene

Unigene Clusters for COASY Gene

CoA synthase:
Representative Sequences:

Clone Products

  • Addgene plasmids for COASY

Alternative Splicing Database (ASD) splice patterns (SP) for COASY Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP1: - -
SP2:
SP3:
SP4: - - - -
SP5: -
SP6: -
SP7: - -
SP8: -
SP9: - -
SP10:
SP11: - -

Relevant External Links for COASY Gene

GeneLoc Exon Structure for
COASY
ECgene alternative splicing isoforms for
COASY

Expression for COASY Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for COASY Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for COASY Gene

This gene is overexpressed in Salivary gland (11.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for COASY Gene



Protein tissue co-expression partners for COASY Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of COASY Gene:

COASY

SOURCE GeneReport for Unigene cluster for COASY Gene:

Hs.296422

mRNA Expression by UniProt/SwissProt for COASY Gene:

Q13057-COASY_HUMAN
Tissue specificity: Expressed in all tissues examined including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte. Lowest expression in peripheral blood leukocytes and highest in kidney and liver. Isoform 2 is expressed mainly in the brain.

Evidence on tissue expression from TISSUES for COASY Gene

  • Nervous system(4.9)
  • Intestine(4.6)
  • Liver(4.6)
  • Blood(4.4)
  • Muscle(4.4)
  • Skin(3.2)
  • Kidney(3.1)
  • Lung(2.9)
  • Spleen(2.5)

Phenotype-based relationships between genes and organs from Gene ORGANizer for COASY Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • nervous
  • skeletal muscle
  • skeleton
Organs:
Head and neck:
  • brain
  • cerebellum
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • skull
  • tooth
Limb:
  • digit
  • foot
  • hand
  • lower limb
  • toe
  • upper limb
General:
  • peripheral nerve
  • peripheral nervous system
  • spinal cord
genes like me logo Genes that share expression patterns with COASY: view

No data available for mRNA differential expression in normal tissues for COASY Gene

Orthologs for COASY Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for COASY Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia COASY 33 34
  • 99.27 (n)
cow
(Bos Taurus)
Mammalia COASY 33 34
  • 89.67 (n)
dog
(Canis familiaris)
Mammalia COASY 33 34
  • 89.33 (n)
rat
(Rattus norvegicus)
Mammalia Coasy 33
  • 85.71 (n)
mouse
(Mus musculus)
Mammalia Coasy 33 16 34
  • 85.54 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia COASY 34
  • 53 (a)
OneToOne
chicken
(Gallus gallus)
Aves COASY 34
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia COASY 34
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia coasy 33
  • 62.65 (n)
zebrafish
(Danio rerio)
Actinopterygii coasy 33 34
  • 57.43 (n)
Dr.17697 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005460 33
  • 54.48 (n)
fruit fly
(Drosophila melanogaster)
Insecta Ppat-Dpck 33 34
  • 50.52 (n)
worm
(Caenorhabditis elegans)
Secernentea Y65B4A.8 33 34
  • 47.39 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CAB4 34
  • 25 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons COAD 33
  • 48.03 (n)
rice
(Oryza sativa)
Liliopsida Os07g0179400 33
  • 49.16 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 40 (a)
OneToOne
Species where no ortholog for COASY was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for COASY Gene

ENSEMBL:
Gene Tree for COASY (if available)
TreeFam:
Gene Tree for COASY (if available)

Paralogs for COASY Gene

(1) SIMAP similar genes for COASY Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with COASY: view

No data available for Paralogs for COASY Gene

Variants for COASY Gene

Sequence variations from dbSNP and Humsavar for COASY Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs140709867 Pathogenic, Neurodegeneration with brain iron accumulation 6 (NBIA6) [MIM:615643] 42,565,668(+) TAAGA(A/C/T)GCATT nc-transcript-variant, upstream-variant-2KB, reference, missense
rs587777136 Pathogenic 42,562,797(+) CCGTG(C/T)AGGCC intron-variant, nc-transcript-variant, reference, stop-gained
rs1000096293 -- 42,564,550(+) CGAAT(A/G)TTGGG nc-transcript-variant, reference, missense
rs1000202926 -- 42,563,654(+) GGAGG(A/C)AACTC intron-variant
rs1000255382 -- 42,563,936(+) TCTCA(C/T)TGTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for COASY Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv1064012 CNV gain 25217958
esv33998 OTHER inversion 15654335

Variation tolerance for COASY Gene

Residual Variation Intolerance Score: 18.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.21; 39.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for COASY Gene

Human Gene Mutation Database (HGMD)
COASY
SNPedia medical, phenotypic, and genealogical associations of SNPs for
COASY

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COASY Gene

Disorders for COASY Gene

MalaCards: The human disease database

(7) MalaCards diseases for COASY Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
neurodegeneration with brain iron accumulation 6
  • copan
coasy-associated neurodegeneration
  • neurodegeneration with brain iron accumulation 6
coasy protein-associated neurodegeneration
  • neurodegeneration with brain iron accumulation 6
neurodegeneration with brain iron accumulation
  • nbia
neurodegeneration with brain iron accumulation 4
  • mitochondrial protein-associated neurodegeneration
- elite association - COSMIC cancer census association via MalaCards
Search COASY in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

COASY_HUMAN
  • Neurodegeneration with brain iron accumulation 6 (NBIA6) [MIM:615643]: A neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. It is characterized by progressive motor and cognitive dysfunction beginning in childhood or young adulthood. Patients show extrapyramidal motor signs, such as spasticity, dystonia, and parkinsonism. {ECO:0000269 PubMed:24360804}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for COASY

Genetic Association Database (GAD)
COASY
Human Genome Epidemiology (HuGE) Navigator
COASY
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
COASY
genes like me logo Genes that share disorders with COASY: view

No data available for Genatlas for COASY Gene

Publications for COASY Gene

  1. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. (PMID: 11923312) Daugherty M … Osterman A (The Journal of biological chemistry 2002) 2 3 4 60
  2. Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation. (PMID: 24360804) Dusi S … Tiranti V (American journal of human genetics 2014) 3 4 60
  3. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 45 60
  4. CoA synthase is in complex with p85alphaPI3K and affects PI3K signaling pathway. (PMID: 19482007) Breus O … Nemazanyy I (Biochemical and biophysical research communications 2009) 3 22 60
  5. Possible difference in frequencies of genetic polymorphisms of estrogen receptor alpha, estrogen metabolism and P53 genes between estrogen receptor-positive and -negative breast cancers. (PMID: 18820009) Hamaguchi M … Yamashita H (Japanese journal of clinical oncology 2008) 3 45 60

Products for COASY Gene

  • Addgene plasmids for COASY

Sources for COASY Gene