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Aliases for COA7 Gene

Aliases for COA7 Gene

  • Cytochrome C Oxidase Assembly Factor 7 (Putative) 2 3
  • C1orf163 3 4 6
  • SELRC1 3 4 6
  • RESA1 3 4 6
  • Cytochrome C Oxidase Assembly Factor 7 2 3
  • Respiratory Chain Assembly Factor 1 3 4
  • Sel1 Repeat-Containing Protein 1 3 4
  • Beta-Lactamase Hcp-Like Protein 3 4
  • Respiratory Chain Assembly 1 2 3
  • Sel1 Repeat Containing 1 2 3
  • Hcp Beta-Lactamase-Like Protein C1orf163 3
  • Chromosome 1 Open Reading Frame 163 2

External Ids for COA7 Gene

Previous HGNC Symbols for COA7 Gene

  • C1orf163
  • SELRC1

Previous GeneCards Identifiers for COA7 Gene

  • GC01M053154

Summaries for COA7 Gene

GeneCards Summary for COA7 Gene

COA7 (Cytochrome C Oxidase Assembly Factor 7 (Putative)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for COA7 Gene

  • Required for assembly of mitochondrial respiratory chain complex I and complex IV.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for COA7 Gene

Genomics for COA7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for COA7 Gene

52,684,451 bp from pter
52,698,366 bp from pter
13,916 bases
Minus strand

Genomic View for COA7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for COA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for COA7 Gene

No data available for Regulatory Elements for COA7 Gene

Proteins for COA7 Gene

  • Protein details for COA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cytochrome c oxidase assembly factor 7
    Protein Accession:
    Secondary Accessions:
    • Q0P6I7
    • Q9H9Z9

    Protein attributes for COA7 Gene

    231 amino acids
    Molecular mass:
    25709 Da
    Quaternary structure:
    No Data Available

neXtProt entry for COA7 Gene

Proteomics data for COA7 Gene at MOPED

Post-translational modifications for COA7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for COA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for COA7 Gene

Domains for COA7 Gene

Gene Families for COA7 Gene

  • MITOAF :Mitochondrial respiratory chain complex assembly factors

Protein Domains for COA7 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q96BR5
  • Belongs to the hcp beta-lactamase family.
  • Contains 5 Sel1-like repeats.
genes like me logo Genes that share domains with COA7: view

No data available for Suggested Antigen Peptide Sequences for COA7 Gene

Function for COA7 Gene

Molecular function for COA7 Gene

UniProtKB/Swiss-Prot Function:
Required for assembly of mitochondrial respiratory chain complex I and complex IV.

miRNA for COA7 Gene

miRTarBase miRNAs that target COA7

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for COA7

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for COA7 Gene

Localization for COA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for COA7 Gene

Mitochondrion intermembrane space.

Gene Ontology (GO) - Cellular Components for COA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005758 mitochondrial intermembrane space IEA --
genes like me logo Genes that share ontologies with COA7: view

No data available for Subcellular locations from COMPARTMENTS for COA7 Gene

Pathways for COA7 Gene

SuperPathways for COA7 Gene

No Data Available

Interacting Proteins for COA7 Gene

Gene Ontology (GO) - Biological Process for COA7 Gene


No data available for Pathways by source for COA7 Gene

Transcripts for COA7 Gene

mRNA/cDNA for COA7 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for COA7

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for COA7 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d
SP1: - - -
SP2: - -
SP3: -

Relevant External Links for COA7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for COA7 Gene

mRNA expression in normal human tissues for COA7 Gene

Protein differential expression in normal tissues for COA7 Gene

This gene is overexpressed in Serum (64.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for COA7 Gene

genes like me logo Genes that share expressions with COA7: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for COA7 Gene

Orthologs for COA7 Gene

This gene was present in the common ancestor of animals.

Orthologs for COA7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SELRC1 35
  • 88.74 (n)
  • 90.04 (a)
COA7 36
  • 90 (a)
(Canis familiaris)
Mammalia SELRC1 35
  • 89.47 (n)
  • 91.34 (a)
COA7 36
  • 91 (a)
(Mus musculus)
Mammalia Coa7 35
  • 86.15 (n)
  • 90.48 (a)
Selrc1 16
Selrc1 36
  • 90 (a)
(Pan troglodytes)
Mammalia SELRC1 35
  • 99.71 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Selrc1 35
  • 84.85 (n)
  • 90.04 (a)
(Monodelphis domestica)
Mammalia COA7 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia COA7 36
  • 76 (a)
(Gallus gallus)
Aves SELRC1 35
  • 71.01 (n)
  • 65.65 (a)
  • 65 (a)
(Anolis carolinensis)
Reptilia COA7 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia coa7 35
  • 65.22 (n)
  • 64.78 (a)
Str.15655 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.3290 35
(Danio rerio)
Actinopterygii coa7 35
  • 64.04 (n)
  • 60.96 (a)
selrc1 36
  • 61 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13865 35
  • 52.1 (n)
  • 37.84 (a)
CG13865 36
  • 32 (a)
(Caenorhabditis elegans)
Secernentea ZK20.4 35
  • 47.96 (n)
  • 33.49 (a)
ZK20.4 36
  • 29 (a)
Species with no ortholog for COA7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for COA7 Gene

Gene Tree for COA7 (if available)
Gene Tree for COA7 (if available)

Paralogs for COA7 Gene

No data available for Paralogs for COA7 Gene

Variants for COA7 Gene

Sequence variations from dbSNP and Humsavar for COA7 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs366309 -- 52,688,436(-) ATCCT(G/T)TCTCT intron-variant
rs374662 -- 52,698,877(-) TGTGT(G/T)CCAGT upstream-variant-2KB
rs375945 -- 52,698,548(-) CATAG(A/G)TAAGG upstream-variant-2KB
rs385111 -- 52,693,551(+) cggcg(A/G)gccga intron-variant
rs392350 -- 52,692,075(+) agagg(C/T)ctctg intron-variant

Relevant External Links for COA7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for COA7 Gene

Disorders for COA7 Gene

No disorders were found for COA7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for COA7 Gene

Publications for COA7 Gene

  1. C1orf163/RESA1 is a novel mitochondrial intermembrane space protein connected to respiratory chain assembly. (PMID: 24333015) Kozjak-Pavlovic V. … Rudel T. (J. Mol. Biol. 2014) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for COA7 Gene

Sources for COA7 Gene

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