Aliases for COA3 Gene
External Ids for COA3 Gene
Previous HGNC Symbols for COA3 Gene
Previous GeneCards Identifiers for COA3 Gene
This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function. [provided by RefSeq, Nov 2012]
GeneCards Summary for COA3 Gene
COA3 (Cytochrome C Oxidase Assembly Factor 3) is a Protein Coding gene. Diseases associated with COA3 include Mitochondrial Complex Iv Deficiency.
UniProtKB/Swiss-Prot for COA3 Gene
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.