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CNTNAP5 Gene

protein-coding   GIFtS: 50
GCID: GC02P124879

Contactin Associated Protein-Like 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Contactin Associated Protein-Like 51 2
Cell Recognition Molecule Caspr52 3
CASPR53 5
caspr52
Contactin-Associated Protein-Like 52

External Ids:    HGNC: 187481   Entrez Gene: 1296842   Ensembl: ENSG000001550527   OMIM: 6105195   UniProtKB: Q8WYK13   

Export aliases for CNTNAP5 gene to outside databases

Previous GC identifers: GC02P124499 GC02P117103


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CNTNAP5 Gene:
This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as
cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth
factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and
fibrinogen-like domains, and thrombospondin N-terminal-like domains. (provided by RefSeq, Jul 2008)

GeneCards Summary for CNTNAP5 Gene:
CNTNAP5 (contactin associated protein-like 5) is a protein-coding gene. Diseases associated with CNTNAP5 include dyslexia, and bipolar disorder. An important paralog of this gene is CNTNAP1.

UniProtKB/Swiss-Prot: CNTP5_HUMAN, Q8WYK1
Function: May play a role in the correct development and proper functioning of the peripheral and central nervous
system and be involved in cell adhesion and intercellular communication




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CNTNAP5 gene promoter:
         HFH-3   Brachyury   NRSF form 1   FOXD3   NRSF form 2   HNF-1A   FOXI1   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCNTNAP5 promoter sequence
   Search Chromatin IP Primers for CNTNAP5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CNTNAP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.3   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q14.1

CNTNAP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNTNAP5 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P124879:  view genomic region     (about GC identifiers)

Start:
124,782,864 bp from pter      End:
125,672,864 bp from pter
Size:
890,001 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CNTP5_HUMAN, Q8WYK1 (See protein sequence)
Recommended Name: Contactin-associated protein-like 5 precursor  
Size: 1306 amino acids; 145623 Da
Secondary accessions: Q4ZFW2 Q4ZG21 Q53R09 Q53RX1 Q53SG3 Q584P3 Q96MS7

Explore the universe of human proteins at neXtProt for CNTNAP5: NX_Q8WYK1

Explore proteomics data for CNTNAP5 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn282, Asn355, Asn496, Asn571, Asn622
  • Modification sites at PhosphoSitePlus

  • See CNTNAP5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_570129.1  
    ENSEMBL proteins: 
     ENSP00000399013  

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    Cloud-Clone Corp. CLIAs for CNTNAP5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 8):
     IPR000742 EG-like_dom
     IPR013320 ConA-like_subgrp
     IPR001791 Laminin_G
     IPR028874 Caspr2/Caspr5
     IPR008979 Galactose-bd-like

    Graphical View of Domain Structure for InterPro Entry Q8WYK1

    ProtoNet protein and cluster: Q8WYK1

    2 Blocks protein domains:
    IPB000421 Coagulation factor 5/8 type C domain (FA58C)
    IPB001791 Laminin G


    UniProtKB/Swiss-Prot: CNTP5_HUMAN, Q8WYK1
    Similarity: Belongs to the neurexin family
    Similarity: Contains 2 EGF-like domains
    Similarity: Contains 1 F5/8 type C domain
    Similarity: Contains 1 fibrinogen C-terminal domain
    Similarity: Contains 4 laminin G-like domains


    CNTNAP5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CNTP5_HUMAN, Q8WYK1
    Function: May play a role in the correct development and proper functioning of the peripheral and central nervous
    system and be involved in cell adhesion and intercellular communication

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CNTNAP5 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CNTNAP5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CNTNAP5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CNTNAP5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CNTNAP5

    miRNA
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    Block miRNA regulation of human, mouse, rat CNTNAP5 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate CNTNAP5:
    hsa-miR-138-1* hsa-miR-34b* hsa-miR-526b hsa-miR-384 hsa-miR-3714 hsa-miR-449c
    SwitchGear 3'UTR luciferase reporter plasmidCNTNAP5 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CNTNAP5
    Predesigned siRNA for gene silencing in human, mouse, rat CNTNAP5

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    GenScript: all cDNA clones in your preferred vector: CNTNAP5 (NM_130773)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CNTNAP5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNTNAP5

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTNAP5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CNTP5_HUMAN, Q8WYK1: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome2
    cytosol1
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    CNTNAP5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CNTNAP5
    Interactions:

        Search GeneGlobe Interaction Network for CNTNAP5

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--

    CNTNAP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CNTNAP5 (CNTP5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CNTNAP5 gene (2 alternative transcripts): 
    NM_130773.3  NM_138996.1  

    Unigene Cluster for CNTNAP5:

    Contactin associated protein-like 5
    Hs.660653  [show with all ESTs]
    Unigene Representative Sequence: NM_130773
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000423939 ENST00000431078(uc002tno.3 uc010flu.3) ENST00000470921

    miRNA
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    Block miRNA regulation of human, mouse, rat CNTNAP5 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate CNTNAP5:
    hsa-miR-138-1* hsa-miR-34b* hsa-miR-526b hsa-miR-384 hsa-miR-3714 hsa-miR-449c
    SwitchGear 3'UTR luciferase reporter plasmidCNTNAP5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CNTNAP5
    Predesigned siRNA for gene silencing in human, mouse, rat CNTNAP5
    Clone
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    OriGene clones in human, mouse for CNTNAP5 (see all 7)
    OriGene ORF clones in mouse, rat for CNTNAP5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CNTNAP5 (NM_130773)
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CNTNAP5
      QuantiTect SYBR Green Assays in human, mouse, rat CNTNAP5
      QuantiFast Probe-based Assays in human, mouse, rat CNTNAP5

    Additional mRNA sequence: 

    AB077881.1 AK056528.1 

    3 DOTS entries:

    DT.75160538  DT.100742810  DT.97823297 

    11 AceView cDNA sequences:

    BM693542 NM_138996 NM_130773 AB077881 AK056528 AW136921 AI199572 AL707802 
    BX492462 AW896193 AA069426 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CNTNAP5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            


    ECgene alternative splicing isoforms for CNTNAP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CNTNAP5 expression in normal human tissues (normalized intensities)      CNTNAP5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CNTNAP5 Expression
    About this image


    CNTNAP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Cumulus Cells Antral Follicle
     
     Adipose (Muscoskeletal System)
             Mesenchymal Stem Cells Subcutaneous White Adipose
     
     Mesenchymal Stem Cells
             Mesenchymal Stem Cells Subcutaneous White Adipose
    CNTNAP5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CNTNAP5 Protein Expression

    Genevestigator expression for CNTNAP5

    SOURCE GeneReport for Unigene cluster: Hs.660653
        Custom PCR Arrays for CNTNAP5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTNAP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CNTNAP5 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cntnap5a1 , 5 contactin associated protein-like 5A1, 5 84.25(n)1
    85.12(a)1
      1 (51.59 cM)5
    6368081  NM_001077425.11  NP_001070893.11 
     1156847565 
    chicken
    (Gallus gallus)
    Aves CNTNAP51 contactin associated protein-like 5 75.65(n)
    79.05(a)
      424231  NM_001048079.1  NP_001041544.1 
    lizard
    (Anolis carolinensis)
    Reptilia CNTNAP56
    contactin associated protein-like 5
    76(a)
    1 ↔ 1
    1(86647894-87128662)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5691851 novel protein similar to vertebrate contactin associated more 61.58(n)
    57.36(a)
      569185  XM_692552.6  XP_697644.6 
    worm
    (Caenorhabditis elegans)
    Secernentea nlr-11 nlr-1 40.77(n)
    30.19(a)
      178167  NM_069911.4  NP_502312.2 


    ENSEMBL Gene Tree for CNTNAP5 (if available)
    TreeFam Gene Tree for CNTNAP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CNTNAP5 gene
    CNTNAP12  ENSG000002360292  NRXN32  CNTNAP3B2  NRXN22  CNTNAP32  CNTNAP22  CNTNAP42  
    NRXN12  
    7 SIMAP similar genes for CNTNAP5 using alignment to 1 protein entry:     CNTP5_HUMAN:
    CNTNAP2    CASPR4    CNTNAP4    CNTNAP3    CNTNAP3B    CNTNAP1
    WUGSC

    CNTNAP5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CNTNAP5 (see all 19034)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs351722471,2
    C--124466072(+) AAAAAA/-TAATA 1 -- int12Minor allele frequency- -:0.25NA 4
    rs1128156431,2
    C--124578474(+) TTACC-/T/TT  
            
    TTTTT
    1 -- int11CSA 2
    rs1893556631,2
    --124780900(+) ATGAAA/GGAACA 1 -- us2k10--------
    rs1146903241,2
    C,F--124781251(+) GTTGGG/TTGGCA 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs15614611,2
    C--124781258(+) GGCAAC/ATCCTG 1 -- us2k113Minor allele frequency- A:0.11NA WA CSA EA 375
    rs1386479501,2
    --124781270(+) GGACCC/TTAGGT 1 -- us2k10--------
    rs1809144891,2
    --124781337(+) TCAGAA/CCCCTT 1 -- us2k10--------
    rs1859185371,2
    --124781492(+) ATCTAC/GTGACT 1 -- us2k10--------
    rs119025641,2
    C,F,H--124781510(+) TTATCT/CTTAGT 1 -- us2k18Minor allele frequency- C:0.04NS WA NA 914
    rs1491689101,2
    C--124781536(+) AAGAGA/GATCAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CNTNAP5 (124782864 - 125032864 bp, first 250kb of CNTNAP5)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CNTNAP5 (see all 47):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720689CNV Deletion23290073
    esv2720692CNV Deletion23290073
    esv2720691CNV Deletion23290073
    esv2675025CNV Deletion23128226
    esv2720690CNV Deletion23290073
    esv2720693CNV Deletion23290073
    esv2421661CNV Deletion20811451
    esv2720694CNV Deletion23290073
    esv1751956CNV Deletion17803354
    esv2669295CNV Deletion23128226

    Human Gene Mutation Database (HGMD): CNTNAP5
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CNTNAP5
    DNA2.0 Custom Variant and Variant Library Synthesis for CNTNAP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610519    OMIM disorders: --

    5 diseases for CNTNAP5:    About MalaCards
    dyslexia    bipolar disorder    type 1 diabetes    schizophrenia
    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for CNTNAP5:
    Dyslexia

    CNTNAP5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CNTNAP5
    Human Genome Epidemiology (HuGE) Navigator: CNTNAP5 (4 documents)

    Export disorders for CNTNAP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CNTNAP5 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with CNTNAP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics. (PubMed id 19721433)1, 4 McClay J.L....van den Oord E.J. (Mol. Psychiatry 2011)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)1, 4 Barber M.J....Krauss R.M. (PLoS ONE 2010)
    4. A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample. (PubMed id 20451256)1, 4 Djurovic S....Andreassen O.A. (J Affect Disord 2010)
    5. Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. (PubMed id 20346443)1, 4 Pagnamenta A.T....Monaco A.P. (Biol. Psychiatry 2010)
    6. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)1, 4 Levy D....Mitchell G.F. (BMC Med. Genet. 2007)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. New members of the neurexin superfamily: multiple rodent homologues of the human CASPR5 gene. (PubMed id 16845472)1, 9 Traut W....Winking H. (Mamm. Genome 2006)
    9. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    10. Genome-wide association study of multiplex schizophrenia pedigrees. (PubMed id 22885689)1 Levinson D.F....Holmans P.A. (Am J Psychiatry 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 129684 HGNC: 18748 AceView: CNTNAP5 Ensembl:ENSG00000155052 euGenes: HUgn129684
    ECgene: CNTNAP5 H-InvDB: CNTNAP5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CNTNAP5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CNTNAP5 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CNTNAP5 gene:
    Search GeneIP for patents involving CNTNAP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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