Aliases for CNTN6 Gene
External Ids for CNTN6 Gene
Previous GeneCards Identifiers for CNTN6 Gene
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for CNTN6 Gene
CNTN6 (Contactin 6) is a Protein Coding gene. Diseases associated with CNTN6 include masa syndrome and autonomic nervous system neoplasm. Among its related pathways are Developmental Biology and Notch signaling pathway (Pathway Interaction Database). An important paralog of this gene is DSCAML1.
UniProtKB/Swiss-Prot for CNTN6 Gene
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity).