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CNTN6 Gene

protein-coding   GIFtS: 61
GCID: GC03P001109

Contactin 6

  Search for CNTN6
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Contactin 61 2
Neural Adhesion Molecule1 2
Neural Recognition Molecule NB-32 3
NB32 5
contactin-62
hNB-33

External Ids:    HGNC: 21761   Entrez Gene: 272552   Ensembl: ENSG000001341157   OMIM: 6072205   UniProtKB: Q9UQ523   

Export aliases for CNTN6 gene to outside databases

Previous GC identifer: GC03P001063


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CNTN6 Gene:
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a
glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule.
It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing
results in multiple transcript variants. (provided by RefSeq, Jan 2014)

GeneCards Summary for CNTN6 Gene:
CNTN6 (contactin 6) is a protein-coding gene. An important paralog of this gene is CHL1.

UniProtKB/Swiss-Prot: CNTN6_HUMAN, Q9UQ52
Function: Contactins mediate cell surface interactions during nervous system development. Participates in
oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1
activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus.
Involved in motor coordination (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CNTN6 gene promoter:
         Nkx3-1   TBP   Nkx3-1 v4   Sox5   Nkx3-1 v1   C/EBPalpha   CHOP-10   Nkx3-1 v2   POU2F1   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCNTN6 promoter sequence
   Search Chromatin IP Primers for CNTN6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CNTN6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p26-p25   Ensembl cytogenetic band:  3p26.3   HGNC cytogenetic band: 3p26-p25

CNTN6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNTN6 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P001109:  view genomic region     (about GC identifiers)

Start:
1,134,260 bp from pter      End:
1,445,901 bp from pter
Size:
311,642 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CNTN6_HUMAN, Q9UQ52 (See protein sequence)
Recommended Name: Contactin-6 precursor  
Size: 1028 amino acids; 113956 Da
Subunit: Interacts with PTPRG
Secondary accessions: Q2KHM2

Explore the universe of human proteins at neXtProt for CNTN6: NX_Q9UQ52

Explore proteomics data for CNTN6 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn65, Asn193, Asn368, Asn377, Asn468, Asn659, Asn765, Asn860, Asn865, Asn895,
                                 Asn931, Asn956, Asn957
  • Modification sites at PhosphoSitePlus

  • See CNTN6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001276009.1  NP_001276010.1  NP_055276.1  

    ENSEMBL proteins: 
     ENSP00000407822   ENSP00000380616   ENSP00000341882   ENSP00000408460   ENSP00000377804  
     ENSP00000442791  
    Reactome Protein details: Q9UQ52

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    ISET: Immunoglobulin superfamily / I-set domain containing

    Selected InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR003961 Fibronectin_type3
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9UQ52

    ProtoNet protein and cluster: Q9UQ52

    1 Blocks protein domain: IPB013098 Immunoglobulin I-set

    UniProtKB/Swiss-Prot: CNTN6_HUMAN, Q9UQ52
    Similarity: Belongs to the immunoglobulin superfamily. Contactin family
    Similarity: Contains 4 fibronectin type-III domains
    Similarity: Contains 6 Ig-like C2-type (immunoglobulin-like) domains


    Find genes that share domains with CNTN6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CNTN6_HUMAN, Q9UQ52
    Function: Contactins mediate cell surface interactions during nervous system development. Participates in
    oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1
    activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus.
    Involved in motor coordination (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CNTN6           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cntn6):
     behavior/neurological  nervous system 

    Find genes that share phenotypes with CNTN6           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cntn6tm1Kwat for CNTN6

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CNTN6
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CNTN6_HUMAN, Q9UQ52: Cell membrane; Lipid-anchor, GPI-anchor (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    peroxisome2
    cytoskeleton1
    cytosol1
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0031225anchored component of membrane IEA--

    Find genes that share ontologies with CNTN6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CNTN6 About    
    See pathways by source

    SuperPathContained pathways About
    1L1CAM interactions
    Axon guidance0.63
    L1CAM interactions0.36
    Developmental Biology0.63
    CHL1 interactions0.00
    2Transcription factors in neurogenesis
    Transcription factors in neurogenesis
    3Notch Signaling Pathways
    Notch Signaling Pathways
    4Notch signaling pathway (Pathway Interaction Database)
    Notch signaling pathway


    Find genes that share SuperPaths with CNTN6           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for CNTN6
        Notch Signaling Pathways


    1 BioSystems Pathway for CNTN6
        Notch signaling pathway

    1 Reactome Pathway for CNTN6
        CHL1 interactions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CNTN6
    Interactions:

        Search GeneGlobe Interaction Network for CNTN6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for CNTN6 (Q9UQ523 ENSP000003418824) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHL1O005333, ENSP000002565094I2D: score=1 STRING: ENSP00000256509
    NOTCH1ENSP000002775414STRING: ENSP00000277541
    APH1AENSP000003581054STRING: ENSP00000358105
    APH1BENSP000002618794STRING: ENSP00000261879
    NCSTNENSP000002947854STRING: ENSP00000294785
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0007219Notch signaling pathway IEA--
    GO:0007411axon guidance TAS--
    GO:0007417central nervous system development TAS9486763

    Find genes that share ontologies with CNTN6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CNTN6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CNTN6 gene (3 alternative transcripts): 
    NM_001289080.1  NM_001289081.1  NM_014461.3  

    Unigene Cluster for CNTN6:

    Contactin 6
    Hs.387300  [show with all ESTs]
    Unigene Representative Sequence: AB003592
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446702(uc003boz.3) ENST00000397479 ENST00000350110(uc011asj.2 uc003bpa.3)
    ENST00000413210 ENST00000394261(uc010hbo.2) ENST00000485257 ENST00000539053

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    Additional mRNA sequence: 

    AB003592.1 AK294786.1 AK307814.1 AK314220.1 BC036338.1 BC113118.1 

    3 DOTS entries:

    DT.102823418  DT.91751347  DT.456219 

    Selected AceView cDNA sequences (see all 25):

    BC036338 BX105298 NM_014461 AB003592 BI822908 BX348968 BV175123 BX360208 
    BQ185049 N41858 CA413758 BX953902 CD625692 CD625700 CD625702 CD625694 
    CD625690 N30615 CD625696 R13299 AA701609 CD625698 R14933 R39333 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CNTN6    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6
    SP1:              -                                             
    SP2:              -     -     -     -     -                     
    SP3:              -     -                                       
    SP4:                    -                                       
    SP5:                                                            


    ECgene alternative splicing isoforms for CNTN6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CNTN6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAATGAGT
    CNTN6 Expression
    About this image


    CNTN6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Medulla Oblongata
     
     Testis (Reproductive System)
             Spermatid Seminiferous Tubules
     
     Gonad
             Spermatid Seminiferous Tubules
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Corneal Endothelium
    CNTN6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CNTN6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.387300

    UniProtKB/Swiss-Prot: CNTN6_HUMAN, Q9UQ52
    Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level
    in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CNTN6 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cntn61 , 5 contactin 61, 5 86.78(n)1
    89.47(a)1
      6 (48.93 cM)5
    538701  NM_017383.31  NP_059079.21 
     1044927905 
    chicken
    (Gallus gallus)
    Aves CNTN61 contactin 6 73.99(n)
    75.96(a)
      427597  XM_004944701.1  XP_004944758.1 
    lizard
    (Anolis carolinensis)
    Reptilia CNTN66
    contactin 6
    74(a)
    1 ↔ 1
    2(175893136-176216916)


    ENSEMBL Gene Tree for CNTN6 (if available)
    TreeFam Gene Tree for CNTN6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CNTN6 gene
    CHL12  NEO12  ROBO12  CNTN52  CNTN42  IGDCC42  NRCAM2  L1CAM2  
    ROBO22  CNTN22  NFASC2  CNTN32  DCC2  PRTG2  IGDCC32  ROBO32  
    CNTN12  
    8 SIMAP similar genes for CNTN6 using alignment to 5 protein entries:     CNTN6_HUMAN (see all proteins):
    CNTN3    CNTN4    CNTN5    DKFZp781D102    CNTN2    CNTN1
    MUSK    FGFR1

    Find genes that share paralogs with CNTN6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CNTN6 (see all 8606)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0355094
    A breast cancer sample4--see VAR_0355092 T A mis40--------
    VAR_0355104
    A breast cancer sample4--see VAR_0355102 S C mis40--------
    rs1875094271,2
    --1132647(+) GTTGAC/TCATTG 1 -- us2k10--------
    rs1913370051,2
    --1132662(+) ATTCTA/GTGCGT 1 -- us2k10--------
    rs1412401361,2
    C--1132666(+) TATGCA/GTAATT 1 -- us2k10--------
    rs1503463731,2
    --1132688(+) ATGACC/TAGAAA 1 -- us2k10--------
    rs1838321811,2
    --1132713(+) AGTGGA/GGACAA 1 -- us2k10--------
    rs1885613721,2
    C--1132726(+) GACTAA/TTCAAA 1 -- us2k10--------
    rs749536961,2
    C,F--1132734(+) AAAGCA/GGATTC 1 -- us2k11Minor allele frequency- G:0.12WA 118
    rs731034641,2
    C--1132736(+) AGCAGT/ATTCAA 1 -- us2k11Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for CNTN6 (1134260 - 1384260 bp, first 250kb of CNTN6)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CNTN6 (see all 62):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670366CNV Deletion23128226
    esv2724770CNV Deletion23290073
    esv2662624CNV Deletion23128226
    esv2664438CNV Deletion23128226
    esv2484315CNV Deletion19546169
    esv1669273CNV Deletion17803354
    esv2179526CNV Deletion18987734
    esv2656847CNV Deletion23128226
    esv2422404CNV Duplication17116639
    esv2422485CNV Duplication17116639

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607220    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for CNTN6:
    Hydrocephalus

    Find genes that share disorders with CNTN6           About GenesLikeMe

    Genetic Association Database (GAD): CNTN6
    Human Genome Epidemiology (HuGE) Navigator: CNTN6 (4 documents)

    Export disorders for CNTN6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CNTN6 gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with CNTN6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning and chromosomal localization of neural adhesion molecule, NB-3 in human. (PubMed id 9486763)1, 2, 3, 9 Kamei Y.... Watanabe K. (J. Neurosci. Res. 1998)
    2. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (Carcinogenesis 2012)
    3. Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)1, 4 Saus E....Estivill X. (J Psychiatr Res 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Molecular genetic analysis of a cell adhesion molecule with homology to L1CAM, contactin 6, and contactin 4 candidate chromosome 3p26pter tumor suppressor genes in ovarian cancer. (PubMed id 19509545)1, 9 Manderson E.N....Tonin P.N. (Int. J. Gynecol. Cancer 2009)
    8. Contactins in the neurobiology of autism. (PubMed id 23872404)1 Zuko A....Burbach J.P. (Eur. J. Pharmacol. 2013)
    9. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. (PubMed id 23650146)1 Tang W....Smith N.L. (Genet. Epidemiol. 2013)
    10. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (PLoS Genet. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27255 HGNC: 2176 AceView: CNTN6 Ensembl:ENSG00000134115 euGenes: HUgn27255
    ECgene: CNTN6 H-InvDB: CNTN6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CNTN6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CNTN6 gene:
    Search GeneIP for patents involving CNTN6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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