CNTN3 Gene

Aliases
for CNTN3 gene

Previous GC identifers: GC03M072881 GC03M073925 GC03M074117 GC03M074232

Summaries
for CNTN3 gene

Genomic Views
for CNTN3 gene

RefSeq DNA sequence:

NC_000003.11  NC_018914.1  NT_022459.15  

SwitchGear Promoter luciferase reporter plasmid: CNTN3 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNTN3

CNTN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M074394:  view genomic region     (about GC identifiers)

Proteins
for CNTN3 gene

1 PDB 3D structure from and Proteopedia for CNTN3:

1WJ3 (3D)    

Explore the universe of human proteins at neXtProt for CNTN3: NX_Q9P232

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for CNTN3 (Contactin-3)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for CNTN3
	GenScript Custom Purified and Recombinant Proteins Services for CNTN3
	Sino Biological Recombinant Protein for CNTN3
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CNTN3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for CNTN3 (Contactin-3)
	Browse OriGene Antibodies OriGene Custom Antibody Services for CNTN3
	GenScript Custom Superior Antibodies Services for CNTN3
	Novus Biologicals CNTN3 Antibodies
	Search for Antibodies for CNTN3 at Abcam
	Uscn Antibodies for CNTN3
	ThermoFisher Antibodies for CNTN3

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CNTN3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CNTN3

Protein Domains /
Families
for CNTN3 gene

ProtoNet protein and cluster: Q9P232

Function
for CNTN3 gene

Pathways & Interactions
for CNTN3 gene

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for CNTN3 gene

Transcripts
for CNTN3 gene

Expression
for CNTN3 gene

CNTN3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGATATGCAC

2 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor Cells			Motor Neurons
	Spinal CordSpinal Ventral Columns			Spinal Cord
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 2 LifeMap Cells
	Name			Category
	Sclerotome cells (Primary Cell)			Bone, Cartilage, Somite
	Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNTN3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CNTN3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNTN3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNTN3

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTN3

Orthologs
for CNTN3 gene

Paralogs
for CNTN3 gene

Paralogs for CNTN3 gene

CHL1²  CNTN2²  DSCAM²  CNTN6²  CNTN5²  CNTN4²  NFASC²  NRCAM²  

SDK2²  SDK1²  DSCAML1²  L1CAM²  CNTN1²  

9 SIMAP similar genes for CNTN3 using alignment to 1 protein entry:     CNTN3_HUMAN:

CNTN4    CNTN6    CNTN1    CNTN5    DKFZp781D102    CNTN2

L1CAM    CHL1    NFASC

CNTN3 for paralogs           About GeneDecksing

Genomic Variants
for CNTN3 gene

10/69 NCBI SNPs in CNTN3 are shown (see all 69)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs6302781,2	C	--	74376257(+)	TAATCT/CTTTTT	1	--	int1 trp3		3		WA CSA	5
rs1480781171,2	C	--	74387658(+)	TGTGT-/GTATACA	1	--	int1		0	--	--	--	--
rs26341541,2	C	--	74393548(+)	CAGTGT/GTTTTT	1	--	int1		3		WA NA CSA	5
rs627779621,2	C,	--	74393714(+)	CGCCA-/TTCTCC	1	--	int1		2		NA CSA	4
rs615720541,2	C	--	74395888(+)	TCCAT-/CCAT           GCATC	1	--	int1		1		NA	2
rs113869471,2	C,	--	74408989(+)	CAATTA/-AAAAA	1	--	int1		1		CSA	2
rs344593211,2	C	--	74426093(+)	GAGAC-/AAAAAA	1	--	int1		1		NA	2
rs633262601,2	C	--	74443966(+)	TCTTA-/AAAGAAGA	1	--	int1		0	--	--	--	--
rs711297441,2	C	--	74455927(+)	ACACACA/-TACAA	1	--	int1		1		NA	2
rs342542621,2	C,	--	74477610(+)	TTAACAT/-GTGTG	1	--	int1		2		NA CSA	4

HapMap Linkage Disequilibrium report for CNTN3 (74311719 - 74561719 bp, first 250kb of CNTN3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CNTN3
     3 CNVs: 91361 91360 4340

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNTN3

DNA2.0 Custom Variant and Variant Library Synthesis for CNTN3

Disorders / Diseases
for CNTN3 gene

Publications
for CNTN3 gene

PubMed articles for CNTN3 gene, integrated from 9 sources (see all 18): (articles sorted by number of sources associating them with CNTN3)

Utopia: connect your pdf to the dynamic world of online information

1. Plasmacytoma-associated neuronal glycoprotein, Pang, maps to mouse chromosome 6 and human chromosome 3. (PubMed id 8661054)^{1, 3, 9} Mock B.A....Marcu K.B. (1996)
2. Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members. (PubMed id 11013081)^{1, 2, 9} Kamei Y....Watanabe K. (2000)
3. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)^{1, 2} Muzny D.M....Gibbs R.A. (2006)
4. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{1, 2} Liu T.... Smith R.D. (2005)
5. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)^{1, 2} Nagase T.... Ohara O. (2000)
6. Overlapping and differential expression of BIG-2, BIG-1, TAG-1, and F3: four members of an axon-associated cell adhesion molecule subgroup of the immunoglobulin superfamily. (PubMed id 8586965)^{1, 3} Yoshihara Y....Mori K. (1995)
7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
8. Specific functions of BIG1 and BIG2 in endomembrane o rganization. (PubMed id 20360857)¹ Boal F. and Stephens D.J. (2010)
9. Identification of a genetic variant associated with a bdominal aortic aneurysms on chromosome 3p12.3 by genome wide association. (PubMed id 19497516)¹ Elmore J.R....Carey D.J. (2009)
10. Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. (PubMed id 18272596)¹ Osterfield M....Flanagan J.G. (2008)

External Searches for CNTN3 gene

Genome Databases showing CNTN3 gene

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Specialized Databases showing CNTN3 gene

Products
for CNTN3 gene